Full Text Journal Articles by
Author Ayesha Farooq

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Catherine E Hagen, Ayesha Farooq,

Arch. Pathol. Lab. Med. (Archives of pathology & laboratory medicine)
[2020, 144(6):671-672]

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Inside the courtroom: An analysis of malpractice litigation in gallbladder surgery.

Ayesha Farooq, Junu Bae, Daniel Rice, Amika Moro, Anghela Z Paredes, Anna L Crisp, Monica Windholtz, Kota Sahara, Diamantis I Tsilimigras, J Madison Hyer, Katiuscha Merath, Rittal Mehta, Efthimios Parasidis, Timothy M Pawlik,

BACKGROUND:Cholecystectomy is one of the most commonly performed operations in the United States, yet it still carries up to a 6% risk of major morbidity. Lawsuits are a major source of emotional, financial, and personal stress for surgeons. We sought to characterize malpractice claims associated with gallbladder surgery as well ... Read more >>

Surgery (Surgery)
[2020, :]

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Health expenditures and financial burden among patients with major gastrointestinal cancers relative to other common cancers in the United States.

Daniel R Rice, Ayesha Farooq, J Madison Hyer, Anghela Z Paredes, Junu Bae, Diamantis I Tsilimigras, Timothy M Pawlik,

BACKGROUND:Gastrointestinal cancers contribute substantially to the cost of health care. We sought to quantify and compare the financial burden associated with treatment of gastrointestinal cancers versus other common nongastrointestinal cancers. METHODS:The Medical Expenditure Panel Survey from 2006 to 2015 was used to identify individuals with gastrointestinal cancer, other nongastrointestinal cancer ... Read more >>

Surgery (Surgery)
[2020, 167(6):985-990]

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The Impact of Preoperative CA19-9 and CEA on Outcomes of Patients with Intrahepatic Cholangiocarcinoma.

Amika Moro, Rittal Mehta, Kota Sahara, Diamantis I Tsilimigras, Anghela Z Paredes, Ayesha Farooq, J Madison Hyer, Itaru Endo, Feng Shen, Alfredo Guglielmi, Luca Aldrighetti, Matthew Weiss, Todd W Bauer, Sorin Alexandrescu, George A Poultsides, Shishir K Maithel, Hugo P Marques, Guillaume Martel, Carlo Pulitano, Olivier Soubrane, Bas G Koerkamp, Kazunari Sasaki, Timothy M Pawlik,

BACKGROUND:The objective of the current study was to assess the impact of serum CA19-9 and CEA and their combination on survival among patients undergoing surgery for intrahepatic cholangiocarcinoma (ICC). METHODS:Patients who underwent curative-intent resection of ICC between 1990 and 2016 were identified using a multi-institutional database. Patients were categorized into ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, :]

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Influence of hospital teaching status on the chance to achieve a textbook outcome after hepatopancreatic surgery for cancer among Medicare beneficiaries.

Rittal Mehta, Anghela Z Paredes, Diamantis I Tsilimigras, Amika Moro, Kota Sahara, Ayesha Farooq, Mary Dillhoff, Jordan M Cloyd, Allan Tsung, Aslam Ejaz, Timothy M Pawlik,

BACKGROUND:Assessing composite measures of quality such as textbook outcome may be superior to focusing on individual parameters when evaluating hospital performance. The aim of the current study was to assess the impact of teaching hospital status on the occurrence of a textbook outcome after hepatopancreatic surgery. METHODS:The Medicare Inpatient Standard ... Read more >>

Surgery (Surgery)
[2020, :]

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Induction-remission response in peadiatric acute lymphoblastic leukaemia, Lahore protocol versus UKALL 2011 interim guidelines.

Safia Khan, Saadia Anwar, Muhammad Farooq Latif, Ayesha Farooq, Mahwish Faizan,

OBJECTIVE:To compare the outcome of induction-remission in acute lymphoblastic leukaemia patients treated according to two different guidelines. METHODS:The descriptive retrospective cohort study was conducted at The Children's Hospital Lahore, Pakistan, and comprised clinical information sheets of acute lymphoblastic leukaemia patients from September 2014 to August 2015. Data regarding demographics, risk ... Read more >>

J Pak Med Assoc (JPMA. The Journal of the Pakistan Medical Association)
[2020, 70(4):591-596]

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Comparing textbook outcomes among patients undergoing surgery for cancer at U. S. News & World Report ranked hospitals.

Rittal Mehta, Diamantis I Tsilimigras, Anghela Z Paredes, Kota Sahara, Amika Moro, Ayesha Farooq, Susan White, Aslam Ejaz, Allan Tsung, Mary Dillhoff, Jordan M Cloyd, Timothy M Pawlik,

BACKGROUND:The objective of the current study was to define and compare rates of textbook outcomes (TO) among patients undergoing colorectal, lung, esophagus, liver, and pancreatic surgery for cancer at U.S. News & World Report (USNWR) ranked hospitals. METHODS:Medicare Inpatient Standard Analytic Files 2013-2015 were utilized to examine the relationship of ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2020, 121(6):927-935]

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Dengue and malaria infections in pregnancy : Maternal, fetal and neonatal outcomes at a tertiary care hospital.

Mujtaba Mubashir, Kaleem S Ahmed, Hadika Mubashir, Ayesha Quddusi, Ayesha Farooq, Sheikh Irfan Ahmed, Bushra Jamil, Rahat Qureshi,

BACKGROUND:Malaria and dengue cause major morbidity in developing nations and are more severe in pregnancy. Maternal, fetal, and neonatal outcomes in pregnant patients infected with dengue or malaria were studied. METHODS:The medical records of pregnant women admitted with either dengue or malaria infections from 2011-2015 to this hospital were reviewed. Clinical ... Read more >>

Wien. Klin. Wochenschr. (Wiener klinische Wochenschrift)
[2020, 132(7-8):188-196]

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Quality of Care Among Medicare Patients Undergoing Pancreatic Surgery: Safety Grade, Magnet Recognition, and Leapfrog Minimum Volume Standards-Which Quality Benchmark Matters?

Katiuscha Merath, Rittal Mehta, Diamantis I Tsilimigras, Ayesha Farooq, Kota Sahara, Anghela Z Paredes, Lu Wu, Amika Moro, Aslam Ejaz, Mary Dillhoff, Jordan Cloyd, Allan Tsung, Timothy M Pawlik,

BACKGROUND:The association of national quality benchmarking metrics with postoperative outcomes following complex surgery remains unknown. We assessed the relationship between the "quality trifactor" of Leapfrog minimum volume standards, Hospital Safety Grade A, and Magnet Recognition with outcomes of Medicare patients undergoing pancreatectomy. METHODS:The Standard Analytic Files (SAF) merged with Leapfrog ... Read more >>

J. Gastrointest. Surg. (Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract)
[2020, :]

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Exogenously Applied Ascorbic Acid-Mediated Changes in Osmoprotection and Oxidative Defense System Enhanced Water Stress Tolerance in Different Cultivars of Safflower (Carthamus tinctorious L.).

Ayesha Farooq, Shazia Anwer Bukhari, Nudrat A Akram, Muhammad Ashraf, Leonard Wijaya, Mohammed Nasser Alyemeni, Parvaiz Ahmad,

The present study was conducted to examine the effect of exogenously applied ascorbic acid (AsA) on osmoprotectants and the oxidative defense system in four cultivars (16171, 16183, 16207 and 16246) of safflower under well-watered and water deficit conditions. Water stress (60% field capacity) significantly decreased the shoot and root fresh ... Read more >>

Plants (Basel) (Plants (Basel, Switzerland))
[2020, 9(1):]

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How Safe Are Safety-Net Hospitals? Opportunities to Improve Outcomes for Vulnerable Patients Undergoing Hepatopancreaticobiliary Surgery.

Ayesha Farooq, Anghela Z Paredes, Katiuscha Merath, J Madison Hyer, Rittal Mehta, Kota Sahara, Diamantis I Tsilimigras, Amika Moro, Lu Wu, Jordan Cloyd, Aslam Ejaz, Timothy M Pawlik,

INTRODUCTION:Safety-net hospitals are critical to the US health system as they provide care to vulnerable patients. The effect of hospital safety-net burden on patient outcomes in hepatopancreaticobiliary (HPB) surgery was examined. METHODS:Discharge data between 2004 and 2014 from the National Inpatient Sample were utilized. Hospitals with a safety-net burden were ... Read more >>

J. Gastrointest. Surg. (Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract)
[2019, :]

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Hospital variation in Textbook Outcomes following curative-intent resection of hepatocellular carcinoma: an international multi-institutional analysis.

Diamantis I Tsilimigras, Rittal Mehta, Katiuscha Merath, Fabio Bagante, Anghela Z Paredes, Ayesha Farooq, Francesca Ratti, Hugo P Marques, Silvia Silva, Olivier Soubrane, Vincent Lam, George A Poultsides, Irinel Popescu, Razvan Grigorie, Sorin Alexandrescu, Guillaume Martel, Aklile Workneh, Alfredo Guglielmi, Tom Hugh, Luca Aldrighetti, Itaru Endo, Timothy M Pawlik,

BACKGROUND:Composite measures such as "Textbook Outcome" (TO) may be superior to individual quality metrics to assess surgical care and hospital performance. However, the incidence and factors associated with TO after resection of HCC remain poorly defined. METHODS:Hospital variation in the rates of TO, factors associated with achieving a TO and ... Read more >>

HPB (Oxford) (HPB : the official journal of the International Hepato Pancreato Biliary Association)
[2019, :]

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Evaluation of costs and outcomes of physician-owned hospitals across common surgical procedures.

Junu Bae, J Madison Hyer, Anghela Z Paredes, Ayesha Farooq, Daniel R Rice, Susan White, Diamantis I Tsilimigras, Aslam Ejaz, Timothy M Pawlik,

INTRODUCTION:The Affordable Care Act introduced restrictions on the creation of new physician-owned hospitals (POH). We sought to define whether POH status was associated with differences in care. METHODS:Patients undergoing one of ten surgical procedures were identified using Medicare Standard Analytic Files. Patient and hospital-level characteristics and outcomes between POH and ... Read more >>

Am. J. Surg. (American journal of surgery)
[2019, :]

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CMS Hospital Compare System of Star Ratings and Surgical Outcomes Among Patients Undergoing Surgery for Cancer: Do the Ratings Matter?

Rittal Mehta, Anghela Z Paredes, Diamantis I Tsilimigras, Ayesha Farooq, Kota Sahara, Katiuscha Merath, J Madison Hyer, Susan White, Aslam Ejaz, Allan Tsung, Mary Dillhoff, Jordan M Cloyd, Timothy M Pawlik,

BACKGROUND:The Centers for Medicare and Medicaid Services (CMS) Hospital Compare star rating system has been proposed as a means to assess hospital quality performance. The current study aimed to investigate outcomes and payments among patients undergoing surgery for colorectal, lung, esophageal, pancreatic, and liver cancer across hospital star rating groups. ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2019, :]

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Photodynamic therapy may provide a benefit over systemic chemotherapy among non-surgically managed patients with extrahepatic cholangiocarcinoma.

Lu Wu, Katiuscha Merath, Ayesha Farooq, J Madison Hyer, Diamantis I Tsilimigras, Anghela Z Paredes, Rittal Mehta, Kota Sahara, Feng Shen, Timothy M Pawlik,

BACKGROUND:Systemic chemotherapy is the standard treatment for patients with unresectable extrahepatic cholangiocarcinoma (ECC), however, the survival benefit of chemotherapy is limited. Photodynamic therapy (PDT) has been associated with improved survival among patients with advanced ECC, yet utilization of PDT remains low. We sought to compare the outcomes of patients with ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2019, :]

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Hepatopancreatobiliary Surgery: the Role of Clinical Resources and Variation in Performance of Hospitals Located in "Distressed" Communities.

Ayesha Farooq, Anghela Z Paredes, Katiuscha Merath, Rittal Mehta, Amika Moro, Lu Wu, Kota Sahara, J Madison Hyer, Diamantis I Tsilimigras, Adrian Diaz, Timothy M Pawlik,

INTRODUCTION:The USA has one of the largest known income-based health disparities, with low-income adults being up to five times more likely to report being in poor health. We evaluated the association of hospital zip-code-based distressed communities index (DCI) with post-surgical outcomes following hepatopancreatobiliary (HPB) surgery. METHODS:Adults undergoing HPB surgery were ... Read more >>

J. Gastrointest. Surg. (Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract)
[2019, :]

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Potential survival benefit of radiofrequency ablation for small solitary intrahepatic cholangiocarcinoma in nonsurgically managed patients: A population-based analysis.

Lu Wu, Diamantis I Tsilimigras, Ayesha Farooq, J Madison Hyer, Katiuscha Merath, Anghela Z Paredes, Rittal Mehta, Kota Sahara, Feng Shen, Timothy M Pawlik,

BACKGROUND:Little data regarding the selection of nonsurgical therapies for localized intrahepatic cholangiocarcinoma (ICC) are available. METHODS:A cohort of nonsurgically managed patients with American Joint Commission on Cancer clinical stage I/II ICC in the United States from 2004 to 2013 were identified in the National Cancer Database. Overall survival (OS) was ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2019, 120(8):1358-1364]

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Utilizing Machine Learning for Pre- and Postoperative Assessment of Patients Undergoing Resection for BCLC-0, A and B Hepatocellular Carcinoma: Implications for Resection Beyond the BCLC Guidelines.

Diamantis I Tsilimigras, Rittal Mehta, Dimitrios Moris, Kota Sahara, Fabio Bagante, Anghela Z Paredes, Ayesha Farooq, Francesca Ratti, Hugo P Marques, Silvia Silva, Olivier Soubrane, Vincent Lam, George A Poultsides, Irinel Popescu, Razvan Grigorie, Sorin Alexandrescu, Guillaume Martel, Aklile Workneh, Alfredo Guglielmi, Tom Hugh, Luca Aldrighetti, Itaru Endo, Timothy M Pawlik,

BACKGROUND:There is an ongoing debate about expanding the resection criteria for hepatocellular carcinoma (HCC) beyond the Barcelona Clinic Liver Cancer (BCLC) guidelines. We sought to determine the factors that held the most prognostic weight in the pre- and postoperative setting for each BCLC stage by applying a machine learning method. METHODS:Patients ... Read more >>

Ann. Surg. Oncol. (Annals of surgical oncology)
[2020, 27(3):866-874]

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U.S. News and World Report hospital ranking and surgical outcomes among patients undergoing surgery for cancer.

Rittal Mehta, Katiuscha Merath, Ayesha Farooq, Kota Sahara, Diamantis I Tsilimigras, Aslam Ejaz, J Madison Hyer, Anghela Z Paredes, Mary Dillhoff, Jordan M Cloyd, Timothy M Pawlik,

BACKGROUND:Despite the popularity of the U.S. News and World Report (USNWR) hospital rankings among the general public, the relationship between hospital rankings and actual patient outcomes for major cancers remains poorly investigated. METHODS:Medicare Inpatient Standard Analytic Files were queried from 2013-2015 to assess the relationship of postoperative outcomes and Medicare ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2019, 120(8):1327-1334]

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Dietary Patterns, Exercise, and the Metabolic Syndrome Among Young People in Urban Pakistan (Lahore).

Muhammad Saad Malik, Wahhaj Qayyum, Ayesha Farooq, Ahmed Waqas, Ahmed Bashir Sukhera, Muhammad Ali Khalid, Ammad Anwar Baig,

Background: Increasing urbanization, mechanization, and rural-to-urban migration has led to deranged sleeping patterns, surplus energy intake, and sedentary lifestyles in South Asian young people. This shift poses an insidious health risk for the development of metabolic syndrome (MetS). Early detection is needed because in the South Asian population, this syndrome ... Read more >>

Metab Syndr Relat Disord (Metabolic syndrome and related disorders)
[2020, 18(1):56-64]

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Routine Intensive Care Unit Admission Following Liver Resection: What Is the Value Proposition?

Katiuscha Merath, Marcelo Cerullo, Ayesha Farooq, Joseph K Canner, Jen He, Diamantis I Tsilimigras, Rittal Mehta, Anghela Z Paredes, Kota Sahara, Mary Dillhoff, Allan Tsung, Jordan Cloyd, Aslam Ejaz, Timothy M Pawlik,

INTRODUCTION:The value of routine ICU admission after elective surgery has been debated due to the lack of robust evidence supporting its benefit, as well as the increased incurred costs. We sought to analyze outcomes of patients undergoing hepatectomy who were routinely admitted to the intensive care unit (ICU) compared with ... Read more >>

J. Gastrointest. Surg. (Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract)
[2019, :]

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Impact of Surgeon Volume on Outcomes and Expenditure Among Medicare Beneficiaries Undergoing Liver Resection: the Effect of Minimally Invasive Surgery.

Kota Sahara, Katiuscha Merath, J Madison Hyer, Diamantis I Tsilimigras, Anghela Z Paredes, Ayesha Farooq, Rittal Mehta, Lu Wu, Eliza W Beal, Susan White, Itaru Endo, Timothy M Pawlik,

BACKGROUND:Although the role of annual surgeon volume on perioperative outcomes after liver resection (LR) has been investigated, there is a paucity of data regarding the impact of surgeon volume on outcomes of minimally invasive LR (MILR) versus open LR (OLR). METHODS:Patients undergoing LR between 2013 and 2015 were identified in ... Read more >>

J. Gastrointest. Surg. (Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract)
[2019, :]

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Histologic Evaluation of Malignant Polyps and Low-Stage Colorectal Carcinoma.

Catherine E Hagen, Ayesha Farooq,

CONTEXT.—:With widespread screening for colorectal cancer, the number of early-stage colorectal cancers is increasing. Local excision of pT1 tumors is associated with considerably less morbidity and mortality, but this must be weighed against risk of lymph node metastases. OBJECTIVE.—:To understand histologic prognostic factors associated with adverse outcome in malignant polyps. ... Read more >>

Arch. Pathol. Lab. Med. (Archives of pathology & laboratory medicine)
[2019, 143(12):1450-1454]

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A Woman with Pancreatitis and Hypertriglyceridemia.

Ayesha Farooq, Angela Treml, Jessica M Colón-Franco,

Clin. Chem. (Clinical chemistry)
[2019, 65(10):1216-1218]

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Discordance in prediction of prognosis among patients with intrahepatic cholangiocarcinoma: A preoperative vs postoperative perspective.

Amika Moro, Anghela Z Paredes, Ayesha Farooq, Kota Sahara, Diamantis I Tsilimigras, Rittal Mehta, Itaru Endo, Alfredo Guglielmi, Luca Aldrighetti, Sorin Alexandrescu, Hugo P Marques, Feng Shen, Bas G Koerkamp, Kazunari Sasaki, Timothy M Pawlik, ,

BACKGROUND:The objective of the current study was to characterize patients with intrahepatic cholangiocarcinoma (ICC) undergoing curative-intent surgery with discordant preoperative and postoperative prediction scores and determine factors associated with prediction discrepancy. METHODS:Patients who underwent hepatectomy for ICC between 1990 and 2016 were identified in a multi-institutional international database. Preoperative and ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2019, 120(6):946-955]

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