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Prevalence, Outcomes, and Management of Ventricular Arrhythmias in COVID-19 Patients

Nicola Tarantino, Domenico G. Della Rocca, Fengwei Zou, Aung Lin, Andrea Natale, Luigi Di Biase,

Synopsis We review the current data on epidemiology, the clinical significance, the pathophysiologic mechanisms, and the treatment of VAs in the setting of COVID-19. VAs prevail in 0.15-8% of in hospitalized patients, but only sustained and rapid tachyarrhythmias are purportedly associated with a significant increase in mortality. Multiple factors can ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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Impact of left atrial posterior wall isolation on arrhythmia outcomes in patients with atrial fibrillation undergoing repeat ablation.

Naga Venkata K Pothineni, Aung Lin, David S Frankel, Gregory E Supple, Fermin C Garcia, David Lin, Matthew C Hyman, Ramanan Kumareswaran, Jeffrey Arkles, Michael Riley, Rajat Deo, Andrew E Epstein, Saman Nazarian, Robert D Schaller, David J Callans, Francis E Marchlinski, Pasquale Santangeli, Sanjay Dixit,

<h4>Background</h4>It remains unclear whether additional left atrial posterior wall isolation (LAPWI) beyond pulmonary vein reisolation (PVRI) is beneficial in atrial fibrillation (AF) patients undergoing repeat ablation.<h4>Objective</h4>We sought to assess impact of LAPWI on arrhythmia outcomes in patients undergoing repeat AF ablation.<h4>Methods</h4>All AF patients that underwent repeat ablation between January 2016 ... Read more >>

Heart Rhythm O2 (Heart rhythm O2)
[2021, 2(5):489-497]

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Race Does Not Provide Protection From New-Onset Atrial Fibrillation After Typical Flutter Ablation in Male Veteran Patients.

Aung N Lin, Gary Peng, Naga K Pothineni, Soe P Winn, Samantha N Hall, Rajat Deo, Michael Riley, Andrew E Epstein, Jeffery Arkles, Sanjay Dixit,

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, 7(10):1312-1314]

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Enhanced Fitness of a Helicobacter pylori babA Mutant in a Murine Model.

M Lorena Harvey, Aung Soe Lin, Lili Sun, Tatsuki Koyama, Jennifer H B Shuman, John T Loh, Holly M Scott Algood, Matthew B Scholz, Mark S McClain, Timothy L Cover,

Helicobacter pylori genomes encode over 60 predicted outer membrane proteins (OMPs). Several OMPs in the Hop family act as adhesins, but the functions of most Hop proteins are unknown. To identify <i>hop</i> mutant strains exhibiting differential fitness <i>in vivo</i> compared to <i>in vitro</i>, we used a genetic barcoding method that ... Read more >>

Infect Immun (Infection and immunity)
[2021, 89(10):e0072520]

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Implantable loop recorder for augmenting detection of new-onset atrial fibrillation after typical atrial flutter ablation.

Gary Peng, Aung N Lin, Edmond Obeng-Gyimah, Samantha N Hall, Ya-Wen Yang, Shiquan Chen, Michael Riley, Rajat Deo, Aasima Ali, Jeffery Arkles, Andrew E Epstein, Sanjay Dixit,

<h4>Background</h4>Patients with typical atrial flutter (AFL) undergoing successful cavotricuspid isthmus ablation remain at risk for future development of new-onset atrial fibrillation (AF). Conventional monitoring (CM) techniques have shown AF incidence rates of 18%-50% in these patients.<h4>Objectives</h4>To evaluate whether continuous monitoring using implantable loop recorders (ILRs) would enhance AF detection in ... Read more >>

Heart Rhythm O2 (Heart rhythm O2)
[2021, 2(3):255-261]

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Sex Chromosome Turnover in Bent-Toed Geckos (Cyrtodactylus).

Shannon E Keating, Madison Blumer, L Lee Grismer, Aung Lin, Stuart V Nielsen, Myint Kyaw Thura, Perry L Wood, Evan S H Quah, Tony Gamble,

Lizards and snakes (squamates) are known for their varied sex determining systems, and gecko lizards are especially diverse, having evolved sex chromosomes independently multiple times. While sex chromosomes frequently turnover among gecko genera, intrageneric turnovers are known only from <i>Gekko</i> and <i>Hemidactylus</i>. Here, we used RADseq to identify sex-specific markers ... Read more >>

Genes (Basel) (Genes)
[2021, 12(1):]

Cited: 2 times

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PRECAF Randomized Controlled Trial.

Ling Kuo, David S Frankel, Aung Lin, Jeffrey Arkles, Matthew Hyman, Pasquale Santangeli, Francis E Marchlinski, Saman Nazarian,

<h4>Background</h4>We have previously shown that the presence of dual muscular coronary sinus (CS) to left atrial (LA) connections, coupled with rate-dependent unidirectional block in one limb, is associated with atrial fibrillation (AF) induction. This study sought to examine whether ablation of distal CS to LA connections at a first AF ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2021, 14(1):e008993]

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AHA telemetry guidelines improve telemetry utilization in the inpatient setting.

Sima S Pendharkar, Ibrahim B Barry, Saikrishna Patibandla, Tiffany I Leung, Amol Gupta, Aung Naing Lin, James A Gasperino,

<h4>Objectives</h4>Overuse of telemetry among hospitalized patients results in poor patient care and wasted health care dollars. Guidelines addressing telemetry use have been developed by the American Heart Association (AHA) and are effective when applied to specific clinical practices and high-value care. The purpose of our intervention was to facilitate more ... Read more >>

Am J Manag Care (The American journal of managed care)
[2020, 26(11):476-481]

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Mitogenomic phylogeny of the Asian colobine genus Trachypithecus with special focus on Trachypithecus phayrei (Blyth, 1847) and description of a new species.

Christian Roos, Kristofer M Helgen, Roberto Portela Miguez, Naw May Lay Thant, Ngwe Lwin, Aung Ko Lin, Aung Lin, Khin Mar Yi, Paing Soe, Zin Mar Hein, Margaret Nyein Nyein Myint, Tanvir Ahmed, Dilip Chetry, Melina Urh, E Grace Veatch, Neil Duncan, Pepijn Kamminga, Marcus A H Chua, Lu Yao, Christian Matauschek, Dirk Meyer, Zhi-Jin Liu, Ming Li, Tilo Nadler, Peng-Fei Fan, Le Khac Quyet, Michael Hofreiter, Dietmar Zinner, Frank Momberg,

<i>Trachypithecus</i>, which currently contains 20 species divided into four groups, is the most speciose and geographically dispersed genus among Asian colobines. Despite several morphological and molecular studies, however, its evolutionary history and phylogeography remain poorly understood. Phayre's langur ( <i>Trachypithecus phayrei</i>) is one of the most widespread members of the ... Read more >>

Zool Res (Zoological research)
[2020, 41(6):656-669]

Cited: 1 time

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Periprocedural Acute Kidney Injury in Patients With Structural Heart Disease Undergoing Catheter Ablation of VT.

Ling Kuo, Daniele Muser, Yasuhiro Shirai, Aung Lin, Jackson Liang, Robert D Schaller, Matthew Hyman, Ramanan Kumareswaran, Jeffrey Arkles, Gregory E Supple, David S Frankel, Fermin Garcia, Cory Tschabrunn, Saman Nazarian, Sanjay Dixit, David Lin, Michael P Riley, David J Callans, Rajat Deo, Andrew Epstein, Erica S Zado, Francis E Marchlinski, Pasquale Santangeli,

<h4>Objectives</h4>This study sought to examine the impact of periprocedural acute kidney injury (AKI) in scar-related ventricular tachycardia (VT) patients undergoing radiofrequency catheter ablation (RFCA) on short- and long-term outcomes.<h4>Background</h4>The clinical significance of periprocedural AKI in patients with scar-related VT undergoing RFCA has not been previously investigated.<h4>Methods</h4>This study included 317 consecutive ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2021, 7(2):174-186]

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Strategies for Catheter Ablation of Left Ventricular Papillary Muscle Arrhythmias: An Institutional Experience.

Aung N Lin, Yasuhiro Shirai, Jackson J Liang, Shiquan Chen, Arshneel Kochar, Matthew C Hyman, Pasquale Santangeli, Robert D Schaller, David S Frankel, Jeffrey S Arkles, Ramanan Kumareswaran, Fermin C Garcia, Michael P Riley, Saman Nazarian, David Lin, Erica C Zado, David J Callans, Francis E Marchlinski, Gregory E Supple, Sanjay Dixit,

<h4>Objectives</h4>This study sought to address whether technological innovations such as contact force sensing (CFS) can improve acute and long-term ablation outcomes of left ventricular papillary muscle (LV PAP) ventricular arrhythmias (VAs).<h4>Background</h4>Catheter ablation of LV PAP VAs has been less efficacious than another focal VAs. It remains unclear whether technological innovations ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(11):1381-1392]

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Mapping and ablating ventricular arrhythmias within the coronary venous system.

Sanjay Dixit, Aung Lin,

Indian Pacing Electrophysiol J (Indian pacing and electrophysiology journal)
[2020, 20(4):164-165]

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Temporal Control of the Helicobacter pylori Cag Type IV Secretion System in a Mongolian Gerbil Model of Gastric Carcinogenesis.

Aung Soe Lin, Mark S McClain, Amber C Beckett, Rhonda R Caston, M Lorena Harvey, Beverly R E A Dixon, Anne M Campbell, Jennifer H B Shuman, Neha Sawhney, Alberto G Delgado, John T Loh, M Blanca Piazuelo, Holly M Scott Algood, Timothy L Cover,

The <i>Helicobacter pylori</i> Cag type IV secretion system (T4SS) translocates the effector protein CagA and nonprotein bacterial constituents into host cells. In this study, we infected Mongolian gerbils with an <i>H. pylori</i> strain in which expression of the <i>cagUT</i> operon (required for Cag T4SS activity) is controlled by a TetR/<i>tetO</i> ... Read more >>

mBio (mBio)
[2020, 11(3):]

Cited: 2 times

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Four new Burmese species of Hemiphyllodactylus Bleeker (Squamata: Gekkonidae) from distantly related parapatric clades from the Shan Plateau and Salween Basin.

L Lee Grismer, Perry L Jr Wood, Evan S H Quah, Myint Kyaw Thura, Jamie R Oaks, Aung Lin,

An integrative taxonomic analysis based on morphology, color pattern, and the mitochondrial gene ND2 recovered four new species of Hemiphyllodactylus Bleeker that are endemic to the Shan Plateau or Salween Basin in eastern Myanmar. Hemiphyllodactylus ngwelwini sp. nov. from the Shan Plateau is part of the earlier described "eastern Myanmar ... Read more >>

Zootaxa (Zootaxa)
[2020, 4758(1):zootaxa.4758.1.2]

Cited: 1 time

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Bacterial Energetic Requirements for Helicobacter pylori Cag Type IV Secretion System-Dependent Alterations in Gastric Epithelial Cells.

Aung Soe Lin, Samuel D R Dooyema, Arwen E Frick-Cheng, M Lorena Harvey, Giovanni Suarez, John T Loh, W Hayes McDonald, Mark S McClain, Richard M Peek, Timothy L Cover,

<i>Helicobacter pylori</i> colonizes the stomach in about half of the world's population. <i>H. pylori</i> strains containing the <i>cag</i> pathogenicity island (<i>cag</i> PAI) are associated with a higher risk of gastric adenocarcinoma or peptic ulcer disease than <i>cag</i> PAI-negative strains. The <i>cag</i> PAI encodes a type IV secretion system (T4SS) that ... Read more >>

Infect Immun (Infection and immunity)
[2020, 88(2):]

Cited: 5 times

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Clinical and procedural characteristics predicting need for chronotropic support and permanent pacing post-heart transplantation.

Tuna Ustunkaya, Jackson J Liang, Aung N Lin, Yasuhiro Shirai, Maria Molina, Anjali T Owens, Michael A Acker, Christian A Bermudez, Pasquale Santangeli, Saman Nazarian, Sanjay Dixit, Francis E Marchlinski, David J Callans,

<h4>Background</h4>Postoperative bradycardia can complicate orthotopic heart transplantation (OHT). Previous studies suggested donor age and surgical technique as possible risk factors. However, risk factors in the era of bicaval anastomosis have not been elucidated.<h4>Objective</h4>We sought to examine the association between donor/recipient characteristics with need for chronotropic support and permanent pacemaker (PPM) ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(7):1132-1138]

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Radiofrequency-Assisted Transseptal Access for Atrial Fibrillation Ablation Via a Superior Approach.

Jackson J Liang, Aung Lin, Sanghamitra Mohanty, Daniele Muser, David F Briceno, J David Burkhardt, Gregory E Supple, David J Callans, Sanjay Dixit, Rodney P Horton, Luigi Di Biase, Francis E Marchlinski, Andrea Natale, Pasquale Santangeli,

<h4>Objectives</h4>This study describes the technique and outcomes of atrial fibrillation (AF) ablation via a superior approach in patients with interrupted or absent inferior vena cavas (IVCs).<h4>Background</h4>In patients with interrupted or absent IVCs, transseptal access cannot be obtained via standard femoral venous access. In these patients, alternative strategies are necessary to ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(3):272-281]

Cited: 2 times

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Two new species of Cyrtodactylus Gray, 1827 (Squamata: Gekkonidae) from a karstic archipelago in the Salween Basin of southern Myanmar (Burma).

L Lee Grismer, Perry L Jr Wood, Evan S H Quah, Marta S Grismer, Myint Kyaw Thura, Jamie R Oaks, Aung Lin,

An integrative taxonomic analysis of the 10 species of the Cyrtodactylus sinyineensis group based on squamation, color pattern, and the mitochondrial gene NADH dehydrogenase subunit 2 (ND2) and its flanking tRNA regions, recovered the newly discovered populations from Datt Kyaik and Taung Wine Hills in Kayin State as the new ... Read more >>

Zootaxa (Zootaxa)
[2020, 4718(2):zootaxa.4718.2.1]

Cited: 1 time

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Incidence of Left Atrial Appendage Triggers in Patients With Atrial Fibrillation Undergoing Catheter Ablation.

Mohamed Al Rawahi, Jackson J Liang, Suraj Kapa, Aung Lin, Yasuhiro Shirai, Ling Kuo, Erica S Zado, Matthew C Hyman, Michael P Riley, Saman Nazarian, Fermin C Garcia, David Lin, Robert D Schaller, Jeffery S Arkles, David S Frankel, Gregory E Supple, Ramanan Kumareswaran, David J Callans, Francis E Marchlinski, Sanjay Dixit,

<h4>Objective</h4>This study sought to investigate incidence of left atrial appendage (LAA) triggers of atrial fibrillation (AF) and/or organized atrial tachycardias (OAT) in patients undergoing AF ablation and to evaluate outcomes after ablation.<h4>Background</h4>Although LAA isolation is being increasingly performed during AF ablation, the true incidence of LAA triggers for AF remains ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(1):21-30]

Cited: 2 times

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Discovery of the westernmost population of the genus Ansonia Stoliczka (Anura, Bufonidae) with the description of a new species from the Shan Plateau of eastern Myanmar.

Evan S H Quah, L Lee Grismer, Perry L Jr Wood, Myint Kyaw Thura, Jamie R Oaks, Aung Lin,

A new species of Ansonia is described from the Shan Plateau of Myanmar based on an integrative taxonomic analysis that differentiates it from all other congeners. Molecular phylogenetic analyses based on the mitochondrial genes 12S and 16S rRNA and tRNA-val recover A. kyaiktiyoensis sp. nov. as the sister species to ... Read more >>

Zootaxa (Zootaxa)
[2019, 4656(3):zootaxa.4656.3.11]

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A new species of Bent-toed Gecko (Squamata, Gekkonidae, Cyrtodactylus) from the Shan Plateau in eastern Myanmar (Burma).

L Lee Grismer, Perry L Jr Wood, Evan S H Quah, Myint Kyaw Thura, Jamie R Oaks, Aung Lin,

An integrative taxonomic analysis of the Cyrtodactylus linnwayensis group of the Shan Plateau recovered two new populations from isolated karst habitats near Pinlaung Town, Shan State as a new species, C. pinlaungensis sp. nov. Cyrtodactylus pinlaungensis sp. nov. is most closely related to a clade comprising C. linnwayensis and C. ... Read more >>

Zootaxa (Zootaxa)
[2019, 4624(3):zootaxa.4624.3.1]

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Two sides of the same coin – Wildmeat consumption and illegal wildlife trade at the crossroads of Asia

J F McEvoy, G Connette, Q Huang, Paing Soe, Khin Htet Htet Pyone, M Valitutto, Yan Lin Htun, Aung Naing Lin, Aung Lwin Thant, Wai Yan Htun, Kaung Htet Paing, Khine Khine Swe, Myint Aung, Sapai Min, M Songer, P Leimgruber,

Domestic trade and consumption of wildmeat is intricately linked with the international trade of wildlife and together they are driving a biodiversity crisis across Southeast Asia. Forming a key juncture between countries and bioregions, Myanmar is an important piece of this puzzle and acts as a source and a conduit ... Read more >>

Biol Conserv (Biological conservation.)
[2019, :Not Available]

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A new species of forest-dwelling Cyrtodactylus Gray (Squamata: Gekkonidae) from the Indawgyi Wildlife Sanctuary, Kachin State, Myanmar.

L Lee Grismer, Perry L Jr Wood, Evan S H Quah, Myint Kyaw Thura, Mark W Herr, Aung Ko Lin,

A herpetological survey of the Indawgyi Wildlife Sanctuary in Kachin State, Myanmar resulted in the discovery of a new species of Cyrtodactylus Gray along the eastern watershed of the Mokso Mountains. An integrative taxonomic analysis based on the mitochondrial ND2 gene, morphology, and color pattern recovered this new species, Cyrtodactylus ... Read more >>

Zootaxa (Zootaxa)
[2019, 4623(1):zootaxa.4623.1.1]

Cited: 1 time

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Clinical and electrophysiological characteristics of idiopathic ventricular arrhythmias originating from the slow pathway region.

David F Briceño, Jackson J Liang, Yasuhiro Shirai, Timothy M Markman, Andres Enriquez, Aung Lin, Pasquale Santangeli, Michael P Riley, Robert D Schaller, Saman Nazarian, David Lin, Ramanan Kumareswaram, Jeffery S Arkles, Mathew C Hyman, Gregory E Supple, David S Frankel, Fermin C Garcia, David J Callans, Francis E Marchlinski, Sanjay Dixit,

<h4>Background</h4>The slow pathway region (SPR) is commonly targeted during ablation of atrioventricular nodal reentrant tachycardia. However, its role in idiopathic ventricular arrhythmias (IVAs) remains unknown.<h4>Objective</h4>The purpose of this study was to describe the electrocardiographic and electrophysiological characteristics of IVAs that were successfully ablated from the SPR.<h4>Methods</h4>Medical records of consecutive patients ... Read more >>

Heart Rhythm (Heart rhythm)
[2019, 16(9):1421-1428]

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Electrocardiographic and Electrophysiologic Characteristics of Idiopathic Ventricular Arrhythmias Originating From the Basal Inferoseptal Left Ventricle.

Jackson J Liang, Yasuhiro Shirai, David F Briceño, Daniele Muser, Andres Enriquez, Aung Lin, Matthew C Hyman, Ramanan Kumareswaran, Jeffrey S Arkles, Pasquale Santangeli, Robert D Schaller, Gregory E Supple, David S Frankel, Rajat Deo, Andrew E Epstein, Fermin C Garcia, Michael P Riley, Saman Nazarian, David Lin, David J Callans, Francis E Marchlinski, Sanjay Dixit,

<h4>Objectives</h4>This study sought to characterize ventricular arrhythmia (VA) ablated from the basal inferoseptal left ventricular endocardium (BIS-LVe) and identify electrocardiographic characteristics to differentiate from inferobasal crux (IBC) VA.<h4>Background</h4>The inferior basal septum is an uncommon source of idiopathic VAs, which can arise from its endocardial or epicardial (crux) aspect. Because the ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2019, 5(7):833-842]

Cited: 1 time

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