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Author Athem Boulahdour


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Pharmacological profile of 6,12-dihydro-3-methoxy-1-benzopyrano[3,4-b] [1,4]benzothiazin-6-one, a novel human estrogen receptor agonist.

Yves Jacquot, Anny Cleeren, Ioanna Laios, Ma Yan, Athem Boulahdour, Laurent Bermont, Bernard Refouvelet, GĂ©rard Adessi, Guy Leclercq, Alain Xicluna,

Pharmacological studies were carried out to characterize further the endocrinological profile and the binding mode to the estrogen receptor (ER) of 6,12-dihydro-3-methoxy-1-benzopyrano[3,4-b][1,4]benzothiazin-6-one (1). Binding experiments were conducted with highly purified recombinant human estrogen receptors hERa and beta. Potent estrogenic activity of compound 1 was assessed by testing its ability to ... Read more >>

Biol. Pharm. Bull. (Biological & pharmaceutical bulletin)
[2002, 25(3):335-341]

Cited: 7 times

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