Full Text Journal Articles by
Author Ariel Roguin

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Historical Advancements and Evolution in Understanding Human Anatomy and Pathology: The Contribution of the Middle Ages.

Alon L Roguin, Ariel Roguin, Nathan Roguin,

Dissections and autopsies are critical for understanding human anatomy, pathology, and uncovering mechanisms of disease. This review presents an historical journey from ancient times until the late Middle Ages. The major steps and developments are summarized with key figures and events presented. ... Read more >>

Adv Anat Pathol (Advances in anatomic pathology)
[2021, 28(3):171-177]

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Acute myocardial infarction treated with novel Resolute Onyx and Orsiro stents in the randomized BIONYX trial.

Eline H Ploumen, Rosaly A Buiten, Paolo Zocca, Carine J M Doggen, Gillian A J Jessurun, Carl E Schotborgh, Ariel Roguin, Peter W Danse, Edouard Benit, Adel Aminian, Rutger L Anthonio, Samer Somi, Gerard C M Linssen, Marc Hartmann, Marlies M Kok, Clemens von Birgelen,

<h4>Objectives</h4>To compare 2-year outcome following treatment with drug-eluting stents (DES) for acute myocardial infarction (MI) versus non-MI clinical syndromes. In acute MI patients, a stent-level comparison was performed, comparing Resolute Onyx versus Orsiro stents.<h4>Background</h4>In patients presenting with acute MI, higher adverse event rates have been reported. So far, no clinical ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2021, :]

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Heart Team/Guidelines Discordance Is Associated With Increased Mortality: Data From a National Survey of Revascularization in Patients With Complex Coronary Artery Disease.

Guy Witberg, Amit Segev, Yaron D Barac, Ehud Raanani, Abid Assali, Ariel Finkelstein, Ariel Roguin, Gideon Sahar, Hana Vaknin-Assa, Gil Bolotin, Amnon Eitan, Robert Klempfner, Ilan Goldenberg, Ran Kornowski,

<h4>Background</h4>Practice guidelines emphasize the role of the SYNTAX score (SS; Synergy Between PCI With TAXUS and Cardiac Surgery) in choosing between percutaneous coronary intervention and coronary artery bypass graft surgery in cases of complex coronary artery disease. There is paucity of data on the implementation of these recommendations in daily ... Read more >>

Circ Cardiovasc Interv (Circulation. Cardiovascular interventions)
[2021, 14(1):e009686]

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Prognosis of Patients With Left Circumflex Artery Acute Myocardial Infarction in Relation to ST-Segment on Admission Electrocardiogram.

Ofer Kobo, Erez Marcusohn, Ariel Roguin, Robert Zukermann, Naama Amsalem, Eugenia Nikolsky, Simcha R Meisel,

<h4>Background</h4>Total thrombotic occlusion of the left circumflex (LCX) artery may present without ST-segment elevations; the clinical outcomes of such patients remain unclear.<h4>Objective</h4>To examine the difference in clinical outcomes between patients with acute myocardial infarction (MI) due to LCX occlusion or stenosis with and without ST-segment elevation.<h4>Methods</h4>The present study is based ... Read more >>

J Invasive Cardiol (The Journal of invasive cardiology)
[2021, 33(1):E20-E24]

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Impact of pre-existent vascular and poly-vascular disease on acute myocardial infarction management and outcomes: An analysis of 2 million patients from the National Inpatient Sample.

Ofer Kobo, Tahmeed Contractor, Mohamed O Mohamed, Purvi Parwani, Timir K Paul, Raktim K Ghosh, M Chadi Alraes, Brijesh Patel, Mohammed Osman, Josef Ludwig, Ariel Roguin, Mamas A Mamas,

<h4>Background</h4>Patients with pre-existing vascular disease are known to have worse outcomes after acute myocardial infarction (AMI). However, there is limited data for outcomes stratified by type and number of vascular territories involved.<h4>Methods</h4>Using the Nationwide Inpatient Sample (2015-2017), we examined outcomes of AMI in patients with pre-existent vascular disease stratified by ... Read more >>

Int J Cardiol (International journal of cardiology)
[2021, 327:1-8]

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Direct Admission of Patients With ST-Segment-Elevation Myocardial Infarction to the Catheterization Laboratory Shortens Pain-to-Balloon and Door-to-Balloon Time Intervals but Only the Pain-to-Balloon Interval Impacts Short- and Long-Term Mortality.

Simcha R Meisel, Michael Kleiner-Shochat, Rami Abu-Fanne, Aaron Frimerman, Asaf Danon, Sa'ar Minha, Yaniv Levi, Alex Blatt, Jameel Mohsen, Avraham Shotan, Ariel Roguin,

Background Shortening the pain-to-balloon (P2B) and door-to-balloon (D2B) intervals in patients with ST-segment-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PPCI) is essential in order to limit myocardial damage. We investigated whether direct admission of PPCI-treated patients with STEMI to the catheterization laboratory, bypassing the emergency department, expedites ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2021, 10(1):e018343]

Cited: 2 times

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Strategies to overcome challenges of transradial coronary angiography and intervention.

Kyriacos Papadopoulos, Arthur Kerner, Sergey Yalonetsky, Eugenia Nikolsky, Yair Feld, Ariel Roguin,

The transradial approach has become the preferred route for performing coronary angiography and interventions. Several studies reported that radial access is associated with significant reduction in vascular complications compared with the femoral access. This technique allows also early ambulation, improves the patient's well-being, and is less expensive. One important limitation ... Read more >>

Rev Cardiovasc Med (Reviews in cardiovascular medicine)
[2020, 21(4):501-505]

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Early Feasibility of Automated Artificial Intelligence Angiography Based Fractional Flow Reserve Estimation.

Ariel Roguin, Ala Abu Dogosh, Yair Feld, Maayan Konigstein, Amir Lerman, Edward Koifman,

Despite the evidence of improved patients' outcome, fractional flow reserve (FFR) is underused in current everyday practice. We aimed to evaluate the feasibility of a novel automated artificial intelligence angiography-based FFR software (AutocathFFR) as a decision supporting tool for interventional cardiologists. AutocathFFR was performed on angiographic images of patients who ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2021, 139:8-14]

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The impact of lockdown enforcement during the SARSCoV-2 pandemic on the timing of presentation and early outcomes of patients with ST-elevation myocardial infarction.

Ofer Kobo, Roi Efraim, Majdi Saada, Natalia Kofman, Ala Abu Dogosh, Yigal Abramowitz, Doron Aronson, Sa'ar Minha, Ariel Roguin, Simcha R Meisel,

<h4>Introduction</h4>Early reports described decreased admissions for acute cardiovascular events during the SarsCoV-2 pandemic. We aimed to explore whether the lockdown enforced during the SARSCoV-2 pandemic in Israel impacted the characteristics of presentation, reperfusion times, and early outcomes of ST-elevation myocardial infarction (STEMI) patients.<h4>Methods</h4>A multicenter prospective cohort comprising all STEMI patients ... Read more >>

PLoS One (PloS one)
[2020, 15(10):e0241149]

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The Degree of the Predischarge Pulmonary Congestion in Patients Hospitalized for Worsening Heart Failure Predicts Readmission and Mortality.

Michael Kleiner-Shochat, Daniel Kapustin, Marat Fudim, Andrew P Ambrosy, Juliya Glantz, Mark Kazatsker, Ilia Kleiner, Jean Marc Weinstein, Gurusher Panjrath, Ariel Roguin, Simcha R Meisel,

<h4>Background</h4>Prediction of readmission and death after hospitalization for heart failure (HF) is an unmet need.<h4>Aim</h4>We evaluated the ability of clinical parameters, NT-proBNP level and noninvasive lung impedance (LI), to predict time to readmission (TTR) and time to death (TTD).<h4>Methods and results</h4>The present study is a post hoc analysis of the ... Read more >>

Cardiology (Cardiology)
[2021, 146(1):49-59]

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Treating diabetic all-comers with contemporary drug-eluting stents: Prespecified comparisons from the BIO-RESORT and the BIONYX randomized trials.

Eline H Ploumen, Rosaly A Buiten, Marlies M Kok, Carine J M Doggen, Ariel Roguin, Gillian A J Jessurun, Carl E Schotborgh, Peter W Danse, Edouard Benit, Adel Aminian, K Gert van Houwelingen, Martin G Stoel, Martijn Scholte, Marc Hartmann, Gerard C M Linssen, Paolo Zocca, Clemens von Birgelen,

<h4>Background</h4>Patients with diabetes have more extensive coronary disease, resulting in higher risks of adverse clinical events following stenting. In all-comer patients, contemporary DES have shown excellent safety and efficacy, but data on diabetic patients are scarce. Separately for the BIO-RESORT and BIONYX trials, we assessed the 2-year clinical outcomes of ... Read more >>

Int J Cardiol (International journal of cardiology)
[2021, 325:37-44]

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Radiation protection in the cardiac catheterisation lab: best practice.

Ariel Roguin, James Nolan,

Heart (Heart (British Cardiac Society))
[2021, 107(1):76-82]

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Impact of coronary lesion complexity in percutaneous coronary intervention: one-year outcomes from the large, multicentre e-Ultimaster registry.

Mohamed O Mohamed, Jawed Polad, David Hildick-Smith, Olivier Bizeau, Ruslan K Baisebenov, Marco Roffi, Andrés Íñiguez-Romo, Bernard Chevalier, Clemens von Birgelen, Ariel Roguin, Adel Aminian, Michael Angioi, Mamas A Mamas,

<h4>Aims</h4>The present study sought to examine the prevalence, clinical characteristics and one-year outcomes of patients undergoing percutaneous coronary intervention (PCI) to complex lesions (multivessel PCI, ≥3 stents, ≥3 lesions, bifurcation with ≥2 stents, total stent length >60 mm or chronic total occlusion [CTO]) in a prospective multicentre registry.<h4>Methods and results</h4>Using ... Read more >>

EuroIntervention (EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology)
[2020, 16(7):603-612]

Cited: 2 times

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Adolf Eugen Fick (1829-1901) - The Man Behind the Cardiac Output Equation.

Ariel Roguin,

Adolf Fick was a German physiologist, born in Kassel in 1829, who studied medicine at the University of Marburg and graduated in 1851. He worked first in Zurich and then in Wurzburg. Most of his studies were based on physics and mathematics, and deep analysis, and only later were proven ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2020, 133:162-165]

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Morphine directly promotes thrombus formation in murine models of vascular thrombosis: A call for revisiting basic tenets.

Rami Abu Fanne, Emad Maraga, Simcha Ron Meisel, Shapira Maanit, Suhair Abdeen, Ariel Roguin, Abd-Alroof Higazi,

Thromb Res (Thrombosis research)
[2020, 193:204-206]

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Good, better or best - What to choose?

Ofer Kobo, Ariel Roguin,

Cardiovasc Revasc Med (Cardiovascular revascularization medicine : including molecular interventions)
[2020, :]

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Rapid rule out for suspected myocardial infarction: is the algorithm appropriate for all?

Erez Marcusohn, Danny Epstein, Ariel Roguin, Robert Zukermann,

AIMS:Patients presenting to the emergency department (ED) with cardiac chest pain and high-sensitive troponin I (HsTnI) less than 5 ng/L have very good prognosis and low risk for major adverse cardiovascular events. The 2015 European Society of Cardiology (ESC) guidelines for non-ST-elevation myocardial infarction (MI)/acute coronary syndrome (ACS) suggests that patients ... Read more >>

Eur Heart J Qual Care Clin Outcomes (European heart journal. Quality of care & clinical outcomes)
[2020, 6(3):193-198]

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Outcomes of Percutaneous Coronary Intervention in Patients With Crohn's Disease and Ulcerative Colitis (from a Nationwide Cohort).

Ofer Kobo, Mohamed O Mohamed, Adam D Farmer, Chadi M Alraies, Tejas Patel, Kamal Sharma, Jim Nolan, Rodrigo Bagur, Ariel Roguin, Mamas A Mamas,

Patients with inflammatory bowel disease (IBD) are at an increased risk of ischemic heart disease. However, there is limited evidence on how their outcomes after percutaneous coronary intervention (PCI) compare with those without IBD. All PCI-related hospitalizations from the National Inpatient Sample from 2004 to 2015 were included, stratified into ... Read more >>

Am J Cardiol (The American journal of cardiology)
[2020, 130:30-36]

Cited: 1 time

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New-generation drug-eluting coronary stents in octogenarians: Patient-level pooled analysis from the TWENTE I-IV trials.

Eline H Ploumen, Rosaly A Buiten, Carine J M Doggen, Martin G Stoel, K Gert van Houwelingen, Carl E Schotborgh, Gillian A J Jessurun, Ariel Roguin, Peter W Danse, Edouard Benit, Adel Aminian, Gerard C M Linssen, Frits H A F de Man, Marc Hartmann, Diedrik G Buiten, Marlies M Kok, Paolo Zocca, Clemens von Birgelen, ,

<h4>Background</h4>Patients aged ≥80 years are often treated with new-generation drug-eluting stents (DES), but data from randomized studies are scarce owing to underrepresentation in most trials. We assessed 1-year clinical outcome of octogenarians treated with new-generation DES versus younger patients.<h4>Methods</h4>We pooled patient-level data of 9,204 participants in the TWENTE, DUTCH PEERS, BIO-RESORT, ... Read more >>

Am Heart J (American heart journal)
[2020, 228:109-115]

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Ultrathin Bioresorbable-Polymer Sirolimus-Eluting Stents Versus Thin Durable-Polymer Everolimus-Eluting Stents for Coronary Revascularization: 3-Year Outcomes From the Randomized BIOFLOW V Trial.

David E Kandzari, Jacques J Koolen, Gheorghe Doros, Hector M Garcia-Garcia, Johan Bennett, Ariel Roguin, Elie G Gharib, Donald E Cutlip, Ron Waksman, ,

<h4>Objectives</h4>The aim of this study was to compare late-term clinical outcomes among patients treated with ultrathin-strut (60-μm) bioresorbable-polymer sirolimus-eluting stents (BP SES) and thin-strut (81μm) durable-polymer everolimus-eluting stents (DP EES).<h4>Background</h4>Emerging evidence from comparative studies of drug-eluting stents demonstrates improved safety and efficacy with ultrathin-strut drug-eluting stents, but limited insight exists ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2020, 13(11):1343-1353]

Cited: 4 times

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Thin Composite-Wire-Strut Zotarolimus-Eluting Stents Versus Ultrathin-Strut Sirolimus-Eluting Stents in BIONYX at 2 Years.

Rosaly A Buiten, Eline H Ploumen, Paolo Zocca, Carine J M Doggen, Gillian A J Jessurun, Carl E Schotborgh, Ariel Roguin, Peter W Danse, Edouard Benit, Adel Aminian, K Gert van Houwelingen, Alexander R Schramm, Martin G Stoel, Samer Somi, Marc Hartmann, Gerard C M Linssen, Clemens von Birgelen,

OBJECTIVES:The aim of this study was to assess 2-year safety and efficacy of the current-generation thin composite-wire-strut durable-polymer Resolute Onyx zotarolimus-eluting stent (ZES), compared with the ultrathin-strut biodegradable-polymer Orsiro sirolimus-eluting stent (SES) in all-comers and a pre-specified small-vessel subgroup analysis. BACKGROUND:The Resolute Onyx ZES is widely used in clinical practice, ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2020, 13(9):1100-1109]

Cited: 2 times

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Modern Stents: Where Are We Going?

Ofer Kobo, Majdi Saada, Simcha R Meisel, Elias Hellou, Aaron Frimerman, Rami Abu Fanne, Jameel Mohsen, Asaf Danon, Ariel Roguin,

Coronary artery stenting is the treatment of choice for patients requiring coronary angioplasty. We describe the major advancements with this technology. There have been significant developments in the design of stents and adjunctive medical therapies. Newer-generation drug-eluting stents (DES) have almost negligible restenosis rates and, when combined with proper anti-platelet ... Read more >>

Rambam Maimonides Med J (Rambam Maimonides medical journal)
[2020, 11(2):]

Cited: 1 time

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Coronary artery ectasia: prevalence, angiographic characteristics and clinical outcome.

Nadav Asher Willner, Scott Ehrenberg, Anees Musallam, Ariel Roguin,

<h4>Objective</h4>Determine coronary artery ectasia (CAE) prevalence and clinical outcome in a large cohort of patients underwent coronary angiography.<h4>Methods</h4>In an 11-year period, between 2006 and 2017, 20 455 coronary angiography studies were performed at a large university centre. Patients diagnosed with CAE based on procedure report were included in the final ... Read more >>

Open Heart (Open heart)
[2020, 7(1):]

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Proximal LAD Treated With Thin-Strut New-Generation Drug-Eluting Stents: A Patient-Level Pooled Analysis of TWENTE I-III.

Ariel Roguin, Rosaly A Buiten, Carine J M Doggen, Ofer Kobo, Paolo Zocca, Peter W Danse, Carl E Schotborgh, Gillian A J Jessurun, K Gert van Houwelingen, Martin G Stoel, R Melvyn Tjon Joe Gin, Gerard C M Linssen, Clemens von Birgelen,

OBJECTIVES:This study sought to assess 2-year clinical outcome following percutaneous coronary intervention (PCI) with thin-strut new-generation drug-eluting stents (DES) in patients treated in proximal left anterior descending artery (P-LAD) versus non-P-LAD lesions. BACKGROUND:In current revascularization guidelines, P-LAD coronary artery stenosis is discussed separately, mainly because of a higher adverse event ... Read more >>

JACC Cardiovasc Interv (JACC. Cardiovascular interventions)
[2020, 13(7):808-816]

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Proximal Left Anterior Descending Artery Treatment Using a Bioresorbable Polymer Coating Sirolimus-Eluting Stent: Real-World Outcomes From the Multicenter Prospective e-Ultimaster Registry.

Pablo Codner, Majdi Saada, Orazbek Sakhov, Jawed Polad, Fazila Tun-Nesa Malik, Shahzad Munir, Mamas Mamas, Jim Crowley, Jacques Monsegu, Luis Perez, Sasko Kedev, David Austin, Ariel Roguin, ,

Background Guidelines recommend heart team discussion and coronary artery bypass graft consideration in patients with proximal left anterior descending (LAD) artery stenosis. Evidence suggests that outcomes of proximal LAD angioplasty might not differ from treatment of nonproximal LAD locations. We aim to determine clinical outcomes of patients undergoing percutaneous coronary ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2019, 8(23):e013786]

Cited: 1 time

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