Full Text Journal Articles by
Author Antonio L Rockwell

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Ubiquitous Knockdown of Mettl3 using TRiP.GL01126 Results in Spermatid Mislocalization During Drosophila Spermatogenesis.

Lauren Rowe, Antonio L Rockwell,

METTL3, the enzyme that catalyzes the m6A RNA modification in Drosophila is highly conserved and essential in various eukaryotic organisms. Mettl3 and its homologs have been linked to biological processes such as gametogenesis. We focused on characterizing the role of METTL3 in Drosophila spermatogenesis. We used the Gal4-UAS system to ... Read more >>

MicroPubl Biol (microPublication biology)
[2022, 2022:]

Cited: 0 times

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Dm Ime4 depletion affects permeability barrier and Chic function in Drosophila spermatogenesis.

Antonio L Rockwell, Cintia F Hongay,

Adenosine methylation of messenger RNA at the N<sup>6</sup> position (m<sup>6</sup>A) is a non-editing modification that can affect several aspects of mRNA metabolism. Dm Ime4, also known as METTL3, MTA, and MTA-70 in other organisms, is the catalytic subunit of the methyltransferase complex that adds this modification. Dm ime4 is evolutionarily ... Read more >>

Mech Dev (Mechanisms of development)
[2020, 164:103650]

Cited: 1 time

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