Full Text Journal Articles by
Author Antoni Torres

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Difficult to Treat Microorganisms in Patients Over 80 Years with Community-Acquired Pneumonia: The Prevalence of PES Pathogens.

Catia Cilloniz, Cristina Dominedo, Héctor José Peroni, Pierluigi Di Giannatale, Carolina Garcia-Vidal, Albert Gabarrus, Adamanthia Liapikou, Adrian Ceccato, Antoni Torres,

Eur. Respir. J. (The European respiratory journal)
[2020, :]

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COVID-19 as a cardiovascular disease: the potential role of chronic endothelial dysfunction.

Jesús F Bermejo-Martin, Raquel Almansa, Antoni Torres, Milagros González-Rivera, David J Kelvin,

Cardiovasc. Res. (Cardiovascular research)
[2020, :]

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Influenza management with new therapies.

Shane OʼSullivan, Antoni Torres, Alejandro Rodriguez, Ignacio Martin-Loeches,

PURPOSE OF REVIEW:Influenza represents a significant treatment burden to critical care services. A variety of treatment strategies exist, with more and more therapeutic avenues opening up as research progresses. We examined both pharmacological and supportive treatment strategies currently available to see how they might be applied in an ICU setting. ... Read more >>

Curr Opin Pulm Med (Current opinion in pulmonary medicine)
[2020, 26(3):215-221]

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Advances in molecular diagnostic tests for pneumonia.

Catia Cilloniz, Adamanthia Liapikou, Antoni Torres,

PURPOSE OF REVIEW:Pneumonia is the main global cause of sepsis, and has been associated with high morbidity and high short and long-term mortality rates. As it may be caused by a wide spectrum of microorganisms, microbial diagnosis is challenging and the choice of adequate therapy remains an important problem. This ... Read more >>

Curr Opin Pulm Med (Current opinion in pulmonary medicine)
[2020, 26(3):241-248]

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Cost-effectiveness Comparison of Ceftazidime/Avibactam Versus Meropenem in the Empirical Treatment of Hospital-acquired Pneumonia, Including Ventilator-associated Pneumonia, in Italy.

Eszter Tichy, Antoni Torres, Matteo Bassetti, Thitima Kongnakorn, Roberto Di Virgilio, Paurus Irani, Claudie Charbonneau,

PURPOSE:Ceftazidime/avibactam (CAZ-AVI) is a fixed-dose combination antibiotic approved in Europe and the United States for patients with hospital-acquired pneumonia, including ventilator-associated pneumonia (HAP/VAP). The economic benefits of a new drug such as CAZ-AVI are required to be assessed against those of available comparators, from the perspective of health care providers ... Read more >>

Clin Ther (Clinical therapeutics)
[2020, :]

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Community-Acquired Pneumonia.

Salvador Sialer, Leonardo F. Difrancesco, Teresa Foix Fabregas, Antoni Torres,

Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality in the world, with an annual incidence ranking from 1.6 to 10.6 per 1.000 people in Europe. The incidence is age related, peaking over 65 years. Up to 75 % of CAP patients with pulmonary diseases need hospitalization, and ... Read more >>

(Metabolism of Human Diseases)
[0, :227-231]

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The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database.

Jean-Louis Vincent, Andrew Ferguson, Peter Pickkers, Stephan M Jakob, Ulrich Jaschinski, Ghaleb A Almekhlafi, Marc Leone, Majid Mokhtari, Luis E Fontes, Philippe R Bauer, Yasser Sakr, ,

BACKGROUND:Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):171]

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Diagnosis of ventilator-associated pneumonia in critically ill adult patients-a systematic review and meta-analysis.

Shannon M Fernando, Alexandre Tran, Wei Cheng, Michael Klompas, Kwadwo Kyeremanteng, Sangeeta Mehta, Shane W English, John Muscedere, Deborah J Cook, Antoni Torres, Otavio T Ranzani, Alison E Fox-Robichaud, Waleed Alhazzani, Laveena Munshi, Gordon H Guyatt, Bram Rochwerg,

The accuracy of the signs and tests that clinicians use to diagnose ventilator-associated pneumonia (VAP) and initiate antibiotic treatment has not been well characterized. We sought to characterize and compare the accuracy of physical examination, chest radiography, endotracheal aspirate (ETA), bronchoscopic sampling cultures (protected specimen brush [PSB] and bronchoalveolar lavage ... Read more >>

Intensive Care Med (Intensive Care Medicine)
[2020, :]

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Are macrolides as effective as fluoroquinolones in Legionella pneumonia?: YES, but….

Antoni Torres, Catia Cillóniz,

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, :]

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Epidemiology of Acute Respiratory Failure in Patients with HM (ICU Only).

Carlos Agustí, Carmen Lucena, Antoni Torres,

Pulmonary complications are common in hematological patients, particularly those receiving a hematological stem cell transplant (HSCT), and a significant percentage of them will require intensive care unit (ICU) admission. Acute respiratory failure in these patients is a threatening event, with a very poor outcome, particularly when mechanical ventilation (MV) is ... Read more >>

(Pulmonary Involvement in Patients with Hematological Malignancies)
[0, :47-55]

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Exacerbation of Bronchiectasis.

Eva Polverino, Edmundo Rosales-Mayor, Antoni Torres,

Please check the hierarchy of the sections and correct if necessary. ... Read more >>

(Bronchiectasis)
[0, :205-222]

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Epidemiology, etiology, and risk factors of bacterial pneumonia.

Antoni Torres, Catia Cillóniz,

Hospital-acquired pneumonia (HAP) is the second most common nosocomial infection after urinary tract infections. The incidence of HAP ranges from 5 to 15 cases per 1000 hospital admissions, and is a frequent problem in general wards (incidence ranging from 1.6 to 3.67 cases per 1000 admissions). ... Read more >>

(Clinical Management of Bacterial Pneumonia)
[0, :7-28]

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Ventilator-associated pneumonia: new principles guiding empiric antibiotic therapy.

Cristina Dominedò, Adrian Ceccato, Antoni Torres,

PURPOSE OF REVIEW:Ventilator-associated pneumonia (VAP) is a serious event in critically ill patients. We aim to review the most recent evidences about VAP, including its cause, the main differences between the American and European guidelines in the definition of risk factors for multidrug-resistant pathogens, the main principles guiding empirical antibiotic ... Read more >>

Curr. Opin. Infect. Dis. (Current opinion in infectious diseases)
[2020, 33(2):182-188]

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The safety of antimicrobials for the treatment of community-acquired pneumonia.

Carla Bastida, Dolors Soy, Antoni Torres,

Introduction: Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide, and its prevalence continues to increase. Despite the efficacy of antimicrobials, their safety and tolerability remain topics of interest and concern for clinicians and patients alike.Areas covered: This review outlines the main antimicrobial classes recommended for the ... Read more >>

Expert Opin Drug Saf (Expert opinion on drug safety)
[2020, 19(5):577-587]

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A pooled analysis of patients with wound infections in the Phase 3 REVIVE trials: randomized, double-blind studies to evaluate the safety and efficacy of iclaprim versus vancomycin for treatment of acute bacterial skin and skin structure infections.

Stephanie Noviello, G Ralph Corey, Thomas L Holland, Thomas Lodise, William O'Riordan, Mark H Wilcox, Thomas M File, Matthew Dryden, Barbara Balser, Amy Scaramucci, Antoni Torres, David B Huang,

Introduction. Iclaprim is a diaminopyrimidine antibiotic for the treatment of acute bacterial skin and skin structure infections (ABSSSI) due to Gram-positive pathogens.Aim. This analysis evaluates patients with wound infections from two Phase 3 trials of ABSSSI.Methodology. Six-hundred-two patients with wound infections from two Phase 3, double-blinded, randomized, multicenter, active controlled ... Read more >>

J. Med. Microbiol. (Journal of medical microbiology)
[2020, :]

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Gender differences in community-acquired pneumonia.

Elena Barbagelata, Catia Cillóniz, Cristina Dominedò, Antoni Torres, Antonello Nicolini, Paolo Solidoro,

INTRODUCTION:Community-acquired pneumonia (CAP) is the most common type of lower respiratory tract infection and a major cause of morbidity and mortality in adults worldwide. Sex and gender play an active role in the incidence and outcomes of major infectious diseases, including CAP. EVIDENCE ACQUISITION:We searched the following electronic databases from ... Read more >>

Minerva Med. (Minerva medica)
[2020, 111(2):153-165]

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Lymphopenic community acquired pneumonia as signature of severe COVID-19 infection.

Jesús F Bermejo-Martin, Raquel Almansa, Rosario Menéndez, Raúl Mendez, David J Kelvin, Antoni Torres,

J. Infect. (The Journal of Infection)
[2020, 80(5):e23-e24]

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Community-Acquired Pneumonia. Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) Guidelines. 2020 Update.

Rosario Menéndez, Catia Cilloniz, Pedro Pablo España, Jordi Almirall, Ane Uranga, Raúl Méndez, David Rigau, Antoni Torres,

The guidelines for community-acquired pneumonia, last published in 2010, have been updated to provide recommendations based on a critical summary of the latest literature to help health professionals make the best decisions in the care of immunocompetent adult patients. The methodology was based on 6 PICO questions (on etiological studies, ... Read more >>

Arch. Bronconeumol. (Archivos de bronconeumologia)
[2020, 56 Suppl 1:1-10]

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Hospital-Acquired Pneumonia. Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) Guidelines. 2019 Update.

Antoni Torres, José Barberán, Adrian Ceccato, Ignacio Martin-Loeches, Miguel Ferrer, Rosario Menéndez, David Rigau,

Hospital-acquired pneumonia (HAP) is the second leading cause of nosocomial infection, and increases morbidity and mortality. It is currently classified into three groups: HAP not requiring artificial ventilation, HAP requiring artificial ventilation, and HAP acquired during artificial ventilation, also known as ventilator-acquired pneumonia (VAP). The latest guidelines for the management ... Read more >>

Arch. Bronconeumol. (Archivos de bronconeumologia)
[2020, 56 Suppl 1:11-19]

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Molecular characterization of methicillin-resistant Staphylococcus aureus clinical strains from the endotracheal tubes of patients with nosocomial pneumonia.

Roberto Cabrera, Laia Fernández-Barat, Anna Motos, Rubén López-Aladid, Nil Vázquez, Mauro Panigada, Francisco Álvarez-Lerma, Yuly López, Laura Muñoz, Pedro Castro, Jordi Vila, Antoni Torres,

BACKGROUND:Among all cases of nosocomial pneumonia, Staphylococcus aureus is the second most prevalent pathogen (17.8%). In Europe, 29.9% of the isolates are oxacillin-resistant. The changing epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) nosocomial infections and the decreasing susceptibility to first-line antibiotics leave clinicians with few therapeutic options. The objective of our ... Read more >>

Antimicrob Resist Infect Control (Antimicrobial resistance and infection control)
[2020, 9(1):43]

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Community-acquired pneumonia in critically ill very old patients: a growing problem.

Catia Cillóniz, Cristina Dominedò, Juan M Pericàs, Diana Rodriguez-Hurtado, Antoni Torres,

Very old (aged ≥80 years) adults constitute an increasing proportion of the global population. Currently, this subgroup of patients represents an important percentage of patients admitted to the intensive care unit. Community-acquired pneumonia (CAP) frequently affects very old adults. However, there are no specific recommendations for the management of critically ill ... Read more >>

Eur Respir Rev (European respiratory review : an official journal of the European Respiratory Society)
[2020, 29(155):]

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Reliability and Minimum Important Difference of Sputum Weight in Bronchiectasis.

Beatriz Herrero-Cortina, Victoria Alcaraz-Serrano, Antoni Torres, Eva Polverino,

BACKGROUND:Despite the widespread use of sputum weight to assess the effect of airway clearance interventions, its psychometric properties have not been evaluated. The purpose of this ad hoc analysis was to determine the test-retest reliability of 24-h sputum weight in clinically stable individuals with bronchiectasis. This study also aimed to ... Read more >>

Respir Care (Respiratory care)
[2020, :]

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How may we improve clinical outcomes for patients hospitalized with acute exacerbations of chronic obstructive pulmonary disease? A narrative review about possible therapeutic and preventive strategies.

Ernesto Crisafulli, Alessandra Manco, Antoni Torres,

Introduction: In a subset of chronic obstructive pulmonary disease (COPD)patients the course of the disease is complicated by a severe acute exacerbations (AECOPD) that may require hospitalization, at which time negative outcomes may occur up to 30 days after discharge. Several predictors of negative outcomes have been documented.Areas covered: We considered ... Read more >>

Expert Rev Respir Med (Expert review of respiratory medicine)
[2020, 14(5):493-500]

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Ceftaroline for severe community-acquired pneumonia: A real-world two-centre experience in Italy and Spain.

Matteo Bassetti, Alessandro Russo, Catia Cilloniz, Daniele Roberto Giacobbe, Antonio Vena, Rosanel Amaro, Elena Graziano, Alex Soriano, Antoni Torres,

BACKGROUND:Ceftaroline is one of latest additions to the armamentarium for treating community-acquired pneumonia (CAP). This study aimed to describe the outcome of severe CAP (SCAP) in a cohort of hospitalised patients treated with ceftaroline. METHODS:A retrospective, observational study of patients with SCAP treated with ceftaroline in two hospitals in Spain ... Read more >>

Int. J. Antimicrob. Agents (International Journal of Antimicrobial Agents)
[2020, 55(4):105921]

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Can Artificial Intelligence Improve the Management of Pneumonia.

Mariana Chumbita, Catia Cillóniz, Pedro Puerta-Alcalde, Estela Moreno-García, Gemma Sanjuan, Nicole Garcia-Pouton, Alex Soriano, Antoni Torres, Carolina Garcia-Vidal,

The use of artificial intelligence (AI) to support clinical medical decisions is a rather promising concept. There are two important factors that have driven these advances: the availability of data from electronic health records (EHR) and progress made in computational performance. These two concepts are interrelated with respect to complex ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(1):]

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