Full Text Journal Articles by
Author Anna Perez

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Adults Born Preterm: Long-Term Health Risks of Former Very Low Birth Weight Infants.

Dominique Singer, Luise Pauline Thiede, Anna Perez,

<h4>Background</h4>Advances in neonatology now enable increasing numbers of very low birth weight neonates (<1500 g) to survive into early adulthood and beyond. What are the implications for their long-term care?<h4>Methods</h4>Selective literature search on the outcome of very low birth weight neonates in adulthood ("adults born preterm").<h4>Results</h4>Robust data are available on ... Read more >>

Dtsch Arztebl Int (Deutsches Arzteblatt international)
[2021, 118(Forthcoming):]

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Whole-Exome Sequencing in Critically Ill Neonates and Infants: Diagnostic Yield and Predictability of Monogenic Diagnosis.

Tasja Scholz, Martin Ernst Blohm, Fanny Kortüm, Tatjana Bierhals, Davor Lessel, Amelie T van der Ven, Jasmin Lisfeld, Theresia Herget, Katja Kloth, Dominique Singer, Anna Perez, Nadia Obi, Jessika Johannsen, Jonas Denecke, René Santer, Christian Kubisch, Philipp Deindl, Maja Hempel,

<h4>Introduction</h4>Monogenic diseases play an important role in critically ill neonates and infants treated in the intensive care unit. This study aimed to determine the diagnostic yield of whole-exome sequencing (WES) for monogenic diseases and identify phenotypes more likely associated with a genetic etiology.<h4>Methods</h4>From March 2017 to 2020, a comprehensive diagnostic ... Read more >>

Neonatology (Neonatology)
[2021, :1-8]

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Improving mental health and wellbeing in elderly people isolated at home due to architectural barriers: A community health intervention.

Ferran Daban, Irene Garcia-Subirats, Victoria Porthé, MªJosé López, Begoña de-Eyto, M Isabel Pasarín, Carme Borrell, Lucía Artazcoz, Anna Pérez, Elia Díez,

<h4>Objectives</h4>To explore the health effects of a community health intervention on older people who are isolated at home due to mobility problems or architectural barriers, to identify associated characteristics and to assess participants' satisfaction.<h4>Design</h4>Quasi-experimental before-after study.<h4>Setting</h4>Five low-income neighbourhoods of Barcelona during 2010-15.<h4>Participants</h4>147 participants, aged ≥59, living in isolation due to ... Read more >>

Aten Primaria (Atencion primaria)
[2021, 53(5):102020]

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Is hematopoietic stem cell transplantation a therapeutic option for mucolipidosis type II?

Luise Sophie Ammer, Sandra Pohl, Sandra Rafaela Breyer, Charlotte Aries, Jonas Denecke, Anna Perez, Martin Petzoldt, Johanna Schrum, Ingo Müller, Nicole Maria Muschol,

<h4>Background</h4>Mucolipidosis type II (MLII) is an ultra-rare lysosomal storage disorder caused by defective lysosomal enzyme trafficking. Clinical hallmarks are craniofacial dysmorphia, cardiorespiratory dysfunction, hepatosplenomegaly, skeletal deformities and neurocognitive retardation. Death usually occurs in the first decade of life and no cure exists. Hematopoietic stem cell transplantation (HSCT) has been performed ... Read more >>

Mol Genet Metab Rep (Molecular genetics and metabolism reports)
[2021, 26:100704]

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Lost in Transition: Health Care Experiences of Adults Born Very Preterm-A Qualitative Approach.

Anna Perez, Luise Thiede, Daniel Lüdecke, Chinedu Ulrich Ebenebe, Olaf von dem Knesebeck, Dominique Singer,

<b>Introduction:</b> Adults Born Very Preterm (ABP) are an underperceived but steadily increasing patient population. It has been shown that they face multiple physical, mental and emotional health problems as they age. Very little is known about their specific health care needs beyond childhood and adolescence. This article focuses on their ... Read more >>

Front Public Health (Frontiers in public health)
[2020, 8:605149]

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Barcelona Salut als Barris: Twelve years' experience of tackling social health inequalities through community-based interventions.

Ferran Daban, M Isabel Pasarín, Carme Borrell, Lucía Artazcoz, Anna Pérez, Ana Fernández, Victoria Porthé, Elia Díez, ,

Community health can reduce inequalities in health and improve the health of the most disadvantaged populations. In 2007, Barcelona Salut als Barris (Barcelona Health in the Neighbourhoods) was launched, a community health programme to reduce social inequalities in health. In 2018, this programme reached the 25 most disadvantaged neighbourhoods of ... Read more >>

Gac Sanit (Gaceta sanitaria)
[2021, 35(3):282-288]

Cited: 1 time

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Interleukin-6 elevation in healthy neonates.

Chinedu Ulrich Ebenebe, Andrea Boiger, Anna Perez, Franziska Lara Mathies, Kurt Hecher, Dominique Singer,

<h4>Objective</h4>This study aimed to identify peripartum and neonatal factors associated with elevated Interleukin-6 levels in the cord blood of neonates without clinical signs of an infection.<h4>Study design</h4>We conducted a prospective single-center study with healthy term and preterm neonates between March and November 2017. We investigated correlations between 21 peripartum factors ... Read more >>

J Perinatol (Journal of perinatology : official journal of the California Perinatal Association)
[2020, 40(2):294-298]

Cited: 1 time

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Mitochondrial Content, but Not Function, Is Altered With a Multimodal Resistance Training Protocol and Adequate Protein Intake in Leucine-Supplemented Pre/Frail Women.

Kathryn J Jacob, Vita Sonjak, Sally Spendiff, Russell T Hepple, Stéphanie Chevalier, Anna Perez, José A Morais,

<b>Background:</b> Frailty is a clinical condition associated with loss of muscle mass and strength (sarcopenia). Mitochondria are centrally implicated in frailty and sarcopenia. Leucine (Leu) can alter mitochondrial content in myocytes, while resistance training (RT) is the strongest stimulus to counteract sarcopenia and may enhance mitochondrial biogenesis. <b>Objective:</b> We determined ... Read more >>

Front Nutr (Frontiers in nutrition)
[2020, 7:619216]

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Reduced Mitochondrial Content, Elevated Reactive Oxygen Species, and Modulation by Denervation in Skeletal Muscle of Prefrail or Frail Elderly Women.

Vita Sonjak, Kathryn J Jacob, Sally Spendiff, Madhusudanarao Vuda, Anna Perez, Kayla Miguez, Fabio C Minozzo, Carole Spake, José A Morais, Russell T Hepple,

Denervation and mitochondrial impairment are implicated in age-related skeletal muscle atrophy and may play a role in physical frailty. We recently showed that denervation modulates muscle mitochondrial function in octogenarian men, but this has not been examined in elderly women. On this basis, we tested the hypothesis that denervation plays ... Read more >>

J Gerontol A Biol Sci Med Sci (The journals of gerontology. Series A, Biological sciences and medical sciences)
[2019, 74(12):1887-1895]

Cited: 6 times

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Target Body Temperature in Very Low Birth Weight Infants: Clinical Consensus in Place of Scientific Evidence.

Anna Perez, Frauke van der Meer, Dominique Singer,

<b>Background:</b> Although thermal care is part of the daily routine in Neonatal Intensive Care Units (NICUs), scientific evidence on what is the appropriate body temperature for very low birth weight infants (VLBWI) is largely lacking. <b>Aim:</b> To find out to what extent the standards of thermal care vary among high-level ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:227]

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Pivotal Role of AKT2 during Dynamic Phenotypic Change of Breast Cancer Stem Cells.

Petra Gener, Diana Rafael, Joaquin Seras-Franzoso, Anna Perez, Luis Alamo Pindado, Glòria Casas, Diego Arango, Yolanda Fernández, Zamira V Díaz-Riascos, Ibane Abasolo, Simó Schwartz,

Therapeutic resistance seen in aggressive forms of breast cancer remains challenging for current treatments. More than half of the patients suffer from a disease relapse, most of them with distant metastases. Cancer maintenance, resistance to therapy, and metastatic disease seem to be sustained by the presence of cancer stem cells ... Read more >>

Cancers (Basel) (Cancers)
[2019, 11(8):]

Cited: 4 times

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Community intervention to reduce social isolation in older adults in disadvantaged urban areas: study protocol for a mixed methods multi-approach evaluation.

María José López, Carolina Lapena, Alba Sánchez, Xavier Continente, Ana Fernández, ,

<h4>Background</h4>The proportion of older people has dramatically increased in recent decades. Moreover, social and demographic trends show a global increase of older people at risk of loneliness and lack of social relationships. The objective of this study was to evaluate the process, the effectiveness and the cost-effectiveness of a planned ... Read more >>

BMC Geriatr (BMC geriatrics)
[2019, 19(1):44]

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[Community prioritization in Barcelona Salut als Barris program].

Esther Sánchez-Ledesma, Anna Pérez, Noelia Vázquez, Irene García-Subirats, Ana Fernández, Ana M Novoa, Ferran Daban, ,

Prioritizing corresponds to the process of selecting and managing health needs identified after diagnosing the community's health needs and assets. Recently, the health needs assessment has been reinforced with the community perspective, providing multiple benefits: it sensitizes and empowers the community about their health, encourages mutual support among its members ... Read more >>

Gac Sanit (Gaceta sanitaria)
[2018, 32(2):187-192]

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Multiple lifestyle risk behaviours and excess weight among adolescents in Barcelona, Spain.

Xavier Continente, Anna Pérez, Albert Espelt, Carles Ariza, María José López,

<h4>Objective</h4>We aimed to analyse the prevalence of having multiple lifestyle risk behaviours (LRB) and the potential relationship between excess weight (including overweight and obesity) and cumulative multiple LRB among adolescents in Barcelona, Spain.<h4>Methods</h4>A cross-sectional study was performed among a representative sample of 3,114 secondary school students in Barcelona. Height and ... Read more >>

Gac Sanit (Gaceta sanitaria)
[2017, 31(4):332-335]

Cited: 1 time

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Adoption of Preventive Measures and Attitudes Toward the H1N1 Influenza Pandemic in Schools.

Anna Pérez, Tània Rodríguez, Maria José López, Xavier Continente, Manel Nebot,

<h4>Background</h4>This study describes the perceived impact of H1N1 influenza and the adoption of the recommended measures to address the pandemic in schools.<h4>Methods</h4>A cross-sectional self-reported survey was conducted in 433 schools in Barcelona addressed to the school principal or the H1N1 influenza designated person. A descriptive analysis was performed, stratifying by ... Read more >>

J Sch Health (The Journal of school health)
[2016, 86(7):534-542]

Cited: 1 time

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Patterns of physical activity and associated factors among teenagers from Barcelona (Spain) in 2012.

Alicia Ruiz-Trasserra, Anna Pérez, Xavier Continente, Kerry O'Brien, Montse Bartroli, Ester Teixidó-Compaño, Albert Espelt,

<h4>Objective</h4>To estimate the prevalence of moderate and vigorous physical activity (MVPA), as defined by the World Health Organisation (WHO), and associated factors among teenagers from Barcelona in 2012.<h4>Methods</h4>Cross-sectional survey to assess risk factors in a representative sample of secondary school students (aged 13-16 years, International Standard Classification of Education [ISCED] ... Read more >>

Gac Sanit (Gaceta sanitaria)
[2017, 31(6):485-491]

Cited: 1 time

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[A good investment: promoting health in cities and neighbourhoods].

Elia Díez, Dory Aviñó, Joan J Paredes-Carbonell, Javier Segura, Óscar Suárez, Maria Dolores Gerez, Anna Pérez, Ferran Daban, Lluís Camprubí,

Local administration is responsible for health-related areas, and evidence of the health impact of urban policies is available. Barriers and recommendations for the full implementation of health promotion in cities and neighbourhoods have been described. The barriers to the promotion of urban health are broad: the lack of leadership and ... Read more >>

Gac Sanit (Gaceta sanitaria)
[2016, 30 Suppl 1:74-80]

Cited: 2 times

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Failed reinnervation in aging skeletal muscle.

Sudhakar Aare, Sally Spendiff, Madhusudanarao Vuda, Daren Elkrief, Anna Perez, Qinghua Wu, Dominique Mayaki, Sabah N A Hussain, Stefan Hettwer, Russell T Hepple,

<h4>Background</h4>Skeletal muscle displays a marked accumulation of denervated myofibers at advanced age, which coincides with an acceleration of muscle atrophy.<h4>Methods</h4>In this study, we evaluated the hypothesis that the accumulation of denervated myofibers in advanced age is due to failed reinnervation by examining muscle from young adult (YA) and very old ... Read more >>

Skelet Muscle (Skeletal muscle)
[2016, 6(1):29]

Cited: 24 times

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Media devices, family relationships and sleep patterns among adolescents in an urban area.

Xavier Continente, Anna Pérez, Albert Espelt, Maria José López,

<h4>Objective</h4>This study aimed to describe sleep patterns and to examine the association between short sleep time and family relationships and the availability of media devices among adolescents.<h4>Methods</h4>A cross-sectional study based on a self-reported questionnaire was performed among a representative sample of adolescents (13-19 years old) enrolled during the 2011-2012 academic ... Read more >>

Sleep Med (Sleep medicine)
[2017, 32:28-35]

Cited: 2 times

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Trends in Inequalities in the Use of Condom by Urban Teenagers in Spain.

Laia Alvarez-Bruned, Xavier Garcia-Continente, Mercè Gotsens, Anna Pérez, Gloria Pérez,

Social and economic inequalities in condom use by adolescents have been reported previously. Also, condom use has declined during the last decade. The aim of the study was to describe trends in the use of condoms in our setting, and how these trends may differ between socioeconomic groups in boys, ... Read more >>

J Urban Health (Journal of urban health : bulletin of the New York Academy of Medicine)
[2015, 92(6):1065-1080]

Cited: 2 times

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Efficacy of memory training in healthy community-dwelling older people: study protocol for a randomized controlled trial.

Anna Pérez, Marta Roqué, Sara Domènech, Rosa Monteserín, Núria Soriano, Xavier Blancafort, Maria Bosom, Cristina Vidal, Montse Petit, Núria Hortal, Carles Gil, Albert Espelt, Maria José López,

<h4>Background</h4>There is limited evidence on the efficacy and social utility of cognitive training. To address this, we have designed a randomized controlled trial to assess the effectiveness of memory training workshops for healthy older people in terms of their short- and long-term impact on cognitive function, health-related quality of life, ... Read more >>

BMC Geriatr (BMC geriatrics)
[2015, 15:113]

Cited: 0 times

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[Tobacco use by adolescents in Barcelona (Spain) and trends in the last 20 years].

Carles Ariza, Xavier García-Continente, Joan Ramon Villalbí, Francesca Sánchez-Martínez, Anna Pérez, Manel Nebot,

<h4>Objectives</h4>Smoking is a preventable cause of early death and the habit starts in adolescence. The aim of this study was to describe tobacco consumption in secondary school students in 2008 and trends in the last 20 years in Barcelona.<h4>Material and methods</h4>We analyzed the trend in tobacco consumption by comparing data ... Read more >>

Gac Sanit (Gaceta sanitaria)
[2014, 28(1):25-33]

Cited: 4 times

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Long-term neurodevelopmental outcome with hypoxic-ischemic encephalopathy.

Anna Perez, Susanne Ritter, Barbara Brotschi, Helene Werner, Jon Caflisch, Ernst Martin, Beatrice Latal,

<h4>Objectives</h4>To determine the long-term neurodevelopmental outcome for children after hypoxic-ischemic encephalopathy (HIE) without major disability, and to examine neonatal injury patterns detected on cerebral magnetic resonance imaging (MRI) in relation to later deficits.<h4>Study design</h4>Prospectively enrolled children with HIE and neonatal cerebral MRI data (n = 68) were examined at a ... Read more >>

J Pediatr (The Journal of pediatrics)
[2013, 163(2):454-459]

Cited: 42 times

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Driving under the influence of alcohol or drugs among adolescents: the role of urban and rural environments.

Laia Font-Ribera, Xavier Garcia-Continente, Anna Pérez, Rosa Torres, Núria Sala, Albert Espelt, Manel Nebot,

This study aimed to describe driving under the influence of alcohol or drugs (DUIAD) and riding in a vehicle with a driver under the influence of alcohol or drugs (RDUIAD) and their associated factors among rural and urban adolescents in Spain. We performed a cross-sectional study including 2067 students from ... Read more >>

Accid Anal Prev (Accident; analysis and prevention)
[2013, 60:1-4]

Cited: 5 times

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Long-term effect of the influenza A/H1N1 pandemic: attitudes and preventive behaviours one year after the pandemic.

Xavier Garcia-Continente, Gemma Serral, María José López, Anna Pérez, Manel Nebot,

This study aimed to describe changes in attitudes and behaviours regarding influenza A infection 1 year after the end of the pandemic. A cross-sectional study was performed based on two population-based telephone surveys including 1027 (February, 2010) and 1000 (February, 2011) participants in Spain. The percentages of the respondents who ... Read more >>

Eur J Public Health (European journal of public health)
[2013, 23(4):679-681]

Cited: 1 time

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