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Author Anja Busse

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Managing dual disorders: a statement by the Informal Scientific Network, UN Commission on Narcotic Drugs.

Nora D Volkow, Marta Torrens, Vladimir Poznyak, Elizabeth Sáenz, Anja Busse, Wataru Kashino, Dzmitry Krupchanka, Devora Kestel, Giovanna Campello, Gilberto Gerra,

World Psychiatry (World psychiatry : official journal of the World Psychiatric Association (WPA))
[2020, 19(3):396-397]

Cited: 0 times

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Reorganization of Substance Use Treatment and Harm Reduction Services during the COVID-19 Pandemic: A Global Survey

Seyed Ramin Radfar, Cornelis De Jong, Ali Farhoudian, Mohsen Ebrahimi, Parnian Rafei, Mehrnoosh Vahidi, Masud Yunesian, Christos Kouimtsidis, Shalini Arunogiri, Omid Massah, Abbas Deylamizadeh, Kathleen Brady, Anja Busse, Marc Potenza, Hamed Ekhtiari, Alexander Mario Baldacchino, ,

Background: The COVID-19 pandemic has impacted people with substance use disorders (SUDs) worldwide, and healthcare systems have reorganized their services in response to the pandemic. Methods: One week after the announcement of the COVID-19 as a pandemic, in a global survey, 177 addiction medicine professionals described COVID-19-related health responses in ... Read more >>

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COVID-19 and Substance Use Disorder: Study Protocol for the International Society of Addiction Medicine Practice and Policy Interest Group Global Survey.

Alexander Baldacchino, Seyed Ramin Radfar, Cornelis De Jong, Parnian Rafei, Masud Yunesian, Gilberto Gerra, Kathleen Brady, Mohsen Ebrahimi, Mehrnoosh Vahidi, Arash Khojasteh Zonoozi, Hossein Mohaddes Ardabili, Anja Busse, Elizabeth Saenz, Giovanna Campello, Kamran Niaz, Hamed Ekhtiari, Ali Farhoudian,

Introduction:As one of the major health problems in the present century, the COVID-19 pandemic affected all parts of the global communities and the health of substance users are potentially at a greater risk of harm. This global study has been designed and conducted by the International Society of Addiction Medicine ... Read more >>

(Basic and clinical neuroscience)
[2020, 11(2):155-162]

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Report on the International Workshop on Drug Prevention and Treatment in Rural Settings Organized by United Nation Office on Drugs and Crime (UNODC) and World Health Organization (WHO).

Giulia Milano, Elizabeth Saenz, Nicolas Clark, Anja Busse, John Gale, Giovanna Campello, Elizabeth Mattfeld, Wadih Maalouf, Hanna Heikkila, Antonietta Martelli, Brian Morales, Gilberto Gerra,

Very little evidence has been reported in literature regarding the misuse of substances in rural areas. Despite the common perception of rural communities as a protective and risk-mitigating environment, the scientific literature demonstrated the existence of many risk factors in rural communities. The Drug Prevention and Health Branch (DHB) of ... Read more >>

Subst Use Misuse (Substance use & misuse)
[2017, 52(13):1801-1807]

Cited: 2 times

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Novel mutation in Hermansky-Pudlak syndrome type 2 with mild immunological phenotype.

Karin Kurnik, Ingrid Bartsch, Andrea Maul-Pavicic, Stephan Ehl, Kirstin Sandrock-Lang, Christoph Bidlingmaier, Nina Rombach, Anja Busse, Bernd H Belohradsky, Josef Müller-Höcker, Charalampos Aslanidis, Gerd Schmitz, Barbara Zieger,

Patients with Hermansky-Pudlak syndrome type 2 (HPS2) present with oculocutaneous albinism, nystagmus, prolonged bleeding time, and increased susceptibility to infections. Twelve HPS2 patients with mutations in the β3A-subunit of the cytosolic adaptor-related protein complex 3 (AP3B1, also called HPS2) have been described so far. Here, we report on a patient ... Read more >>

Platelets (Platelets)
[2013, 24(7):538-543]

Cited: 6 times

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Voluntary treatment, not detention, in the management of opioid dependence.

Nicolas Clark, Anja Busse, Gilberto Gerra,

Bull. World Health Organ. (Bulletin of the World Health Organization)
[2013, 91(2):146-147]

Cited: 4 times

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Deletion of human GP1BB and SEPT5 is associated with Bernard-Soulier syndrome, platelet secretion defect, polymicrogyria, and developmental delay.

Ingrid Bartsch, Kirstin Sandrock, Francois Lanza, Paquita Nurden, Ina Hainmann, Anna Pavlova, Andreas Greinacher, Uta Tacke, Michael Barth, Anja Busse, Johannes Oldenburg, Martin Bommer, Brigitte Strahm, Andrea Superti-Furga, Barbara Zieger,

The bleeding disorder Bernard-Soulier syndrome (BSS) is caused by mutations in the genes coding for the platelet glycoprotein GPIb/IX receptor. The septin SEPT5 is important for active membrane movement such as vesicle trafficking and exocytosis in non-dividing cells (i.e. platelets, neurons). We report on a four-year-old boy with a homozygous ... Read more >>

Thromb. Haemost. (Thrombosis and haemostasis)
[2011, 106(3):475-483]

Cited: 19 times

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Lethal phenotype of mice carrying a Sept11 null mutation.

Sabrina Röseler, Kirstin Sandrock, Ingrid Bartsch, Anja Busse, Heymut Omran, Niki T Loges, Barbara Zieger,

Septins are cytoskeletal GTP-binding proteins involved in processes characterized by active membrane movement, such as cytokinesis, vesicle trafficking and exocytosis. Most septins are expressed ubiquitously, however, some septins accumulate in particular tissues. The ubiquitous SEPT11 also shows high expression levels in the central nervous system and in platelets. Here, SEPT11 ... Read more >>

Biol. Chem. (Biological chemistry)
[2011, 392(8-9):779-781]

Cited: 11 times

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Characterization of human septin interactions.

Kirstin Sandrock, Ingrid Bartsch, Susanne Bläser, Anja Busse, Eileen Busse, Barbara Zieger,

Septins constitute a group of GTP binding proteins that assemble into homo- and hetero-oligomeric complexes and filaments. These higher order septin structures are thought to function like scaffolds and/or diffusion barriers serving as spatial localizers for many proteins with key roles in cell polarity and cell cycle progression. In this ... Read more >>

Biol. Chem. (Biological chemistry)
[2011, 392(8-9):751-761]

Cited: 32 times

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United Nations Office on Drugs and Crime International Network of Drug Dependence Treatment and Rehabilitation Resource Centres: Treatnet.

Juana Tomás-Rosselló, Richard A Rawson, Maria J Zarza, Anne Bellows, Anja Busse, Elizabeth Saenz, Thomas Freese, Mansour Shawkey, Deni Carise, Robert Ali, Walter Ling,

Key to the dissemination of evidence-based addiction treatments is the exchange of experiences and mutual support among treatment practitioners, as well as the availability of accurate addiction training materials and effective trainers. To address the shortage of such resources, the United Nations Office on Drugs and Crime (UNODC) created Treatnet, ... Read more >>

Subst Abus (Substance abuse)
[2010, 31(4):251-263]

Cited: 4 times

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Human endothelial and platelet septin SEPT11: cloning of novel variants and characterisation of interaction partners.

Ingrid Bartsch, Susanne Bläser, Sabrina Röseler, Kirstin Sandrock, Anja Busse, Michael Huber, Hansjörg Rempp, Mareike Lieber, Julia Horn, Cornelia Brendle, Barbara Zieger,

Septins are cytoskeletal GTPases forming heteropolymeric complexes involved in processes characterised by active membrane movement such as cytokinesis, vesicle trafficking, and exocytosis. Septins are expressed in non-mitotic cells such as neurons and platelets. SEPT11 belongs to the SEPT6 group and was identified as interaction partner of SEPT5. We cloned and ... Read more >>

Thromb. Haemost. (Thrombosis and haemostasis)
[2010, 104(6):1201-1210]

Cited: 5 times

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Novel Mutation in Bernard-Soulier Syndrome.

Kirstin Sandrock, Ralf Knöfler, Andreas Greinacher, Birgitt Fürll, Sebastian Gerisch, Ulrich Schuler, Siegmund Gehrisch, Anja Busse, Barbara Zieger,

BACKGROUND: Bernard-Soulier syndrome (BSS) is a severe congenital bleeding disorder characterized by thrombocytopenia, thrombocytopathy and decreased platelet adhesion. BSS results from genetic alterations of the glycoprotein (GP) Ib/IX/V complex. METHODS: We report on a patient demonstrating typical BSS phenotype (thrombocytopenia with giant platelets, bleeding symptoms). However, BSS was not diagnosed ... Read more >>

(Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie)
[2010, 37(5):278-284]

Cited: 5 times

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[Mild cognitive impairment and development of dementia].

Tobias Luck, Anja Busse, Anke Hensel, Matthias C Angermeyer, Steffi G Riedel-Heller,

OBJECTIVE: In order to identify mildly cognitively impaired subjects, MILD COGNITIVE IMPAIRMENT: (MCI) represents a current and well-discussed concept. Prevalence and conversion rates, relative risks and data on the sensitivity and specifity of MCI for the development of dementia will be calculated. METHODS: 980 subjects aged 75 years and over ... Read more >>

Psychiatr Prax (Psychiatrische Praxis)
[2008, 35(7):331-336]

Cited: 6 times

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Mortality in individuals with mild cognitive impairment. Results of the Leipzig Longitudinal Study of the Aged (LEILA75+).

Uta Guehne, Tobias Luck, Anja Busse, Matthias C Angermeyer, Steffi G Riedel-Heller,

OBJECTIVE: This study aimed to investigate whether mortality is higher for individuals suffering from Mild Cognitive Impairment (MCI). METHODS: A community sample of 1,045 dementia-free individuals aged 75 years and over was examined using neuropsychological tests over a 4.5-year period. Data were analyzed with the Cox proportional hazards model after ... Read more >>

Neuroepidemiology (Neuroepidemiology)
[2007, 29(3-4):226-234]

Cited: 25 times

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Progression of mild cognitive impairment to dementia: a challenge to current thinking.

Anja Busse, Matthias C Angermeyer, Steffi G Riedel-Heller,

Studies of conversion from mild cognitive impairment to dementia suggest a linear progression over time. Conversion rates during lifetime may extend to 80-90%.This study examines the time-dependent evolution from mild cognitive impairment to dementia. Current assumptions regarding yearly and lifetime conversion rates are challenged.A community sample of 1045 dementia-free individuals ... Read more >>

Br J Psychiatry (The British journal of psychiatry : the journal of mental science)
[2006, 189:399-404]

Cited: 51 times

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The novel human platelet septin SEPT8 is an interaction partner of SEPT4.

Susanne Bläser, Julia Horn, Paul Würmell, Heike Bauer, Sandra Strümpell, Paquita Nurden, Axel Pagenstecher, Anja Busse, Daniela Wunderle, Ina Hainmann, Barbara Zieger,

Septins are a family of GTP-binding proteins, which are essential for active membrane movement such as cytokinesis and vesicle trafficking. In non-dividing cells (such as platelets and neurons) septins are implicated in exocytosis. Platelets from a SEPT5 knockout mouse showed an altered serotonin secretion and platelet aggregation, suggesting that SEPT5 ... Read more >>

Thromb Haemost (Thrombosis and haemostasis)
[2004, 91(5):959-966]

Cited: 17 times

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Human septin-septin interaction: CDCrel-1 partners with KIAA0202.

Susanne Bläser, Katrin Jersch, Ina Hainmann, Daniela Wunderle, Andrea Zgaga-Griesz, Anja Busse, Barbara Zieger,

Septins are evolutionary conserved cytoskeletal GTPases forming heteropolymer complexes involved in cytokinesis and other cellular processes. CDCrel-1 (cell division cycle related-1) is a recently cloned and characterized human septin which is highly expressed in non-dividing cells, such as neurons. Using a yeast two-hybrid system we demonstrate that CDCrel-1 partners with ... Read more >>

FEBS Lett. (FEBS letters)
[2002, 519(1-3):169-172]

Cited: 20 times

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Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202).

Susanne Bläser, Katrin Jersch, Ina Hainmann, Wolfgang Zieger, Daniela Wunderle, Anja Busse, Barbara Zieger,

SEPT8 (KIAA0202) is a member of the highly conserved septin family. Septins are membrane-associated GTPases which are involved in cytokinesis and cellular morphogenesis. Using the yeast two-hybrid system and the glutathione-S-transferase pull-down assay we previously had identified the SEPT8 (KIAA0202) as interaction partner of the human septin SEPT5 (cell division ... Read more >>

Gene (Gene)
[2003, 312:313-320]

Cited: 19 times

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Mild cognitive impairment: prevalence and incidence according to different diagnostic criteria. Results of the Leipzig Longitudinal Study of the Aged (LEILA75+).

Anja Busse, Jeannette Bischkopf, Steffi G Riedel-Heller, Matthias C Angermeyer,

Although mild cognitive impairment is associated with an increased risk of developing dementia, there has been little work on its incidence and prevalence.To report age-specific prevalence, incidence and predictive validities for four diagnostic concepts of mild cognitive impairment.A community sample of 1045 dementia-free individuals aged 75 years and over was ... Read more >>

Br J Psychiatry (The British journal of psychiatry : the journal of mental science)
[2003, 182:449-454]

Cited: 107 times

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[Prevalence and incidence of dementia among nursing home residents and residents in homes for the aged in comparison to private homes].

Anke Jakob, Anja Busse, Steffi G Riedel-Heller, Micaela Pavlicek, M C Angermeyer,

Based on a representative epidemiological study on dementia, prevalence and incidence rates of institutionalized individuals aged 75 years and older in comparison to those living in private homes are presented. The study was conducted between 1997 and 1999. Core component assessing cognitive function was the SIDAM (Structured Interview for the ... Read more >>

Z Gerontol Geriatr (Zeitschrift fur Gerontologie und Geriatrie)
[2002, 35(5):474-481]

Cited: 20 times

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Adaptation of dementia screening for vision-impaired older persons: administration of the Mini-Mental State Examination (MMSE).

Anja Busse, Astrid Sonntag, Jeannette Bischkopf, Herbert Matschinger, Matthias C Angermeyer,

In epidemiologic field studies on the prevalence and incidence of dementia the problems associated with the cognitive testing of visually impaired individuals are rarely discussed. In the Leipzig Longitudinal Study of the Aged (LEILA 75+) a version of the Mini-Mental State Examination for the visually impaired (MMSE-blind) was employed from ... Read more >>

J Clin Epidemiol (Journal of clinical epidemiology)
[2002, 55(9):909-915]

Cited: 47 times

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