Full Text Journal Articles by
Author Angela Dittmer

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BCL3 expression is strongly associated with the occurrence of breast cancer relapse under tamoxifen treatment in a retrospective cohort study.

Piotr Czapiewski, Maximilian Cornelius, Roland Hartig, Thomas Kalinski, Johannes Haybaeck, Angela Dittmer, Jürgen Dittmer, Atanas Ignatov, Norbert Nass,

Patients with estrogen receptor positive breast cancer are usually receiving an anti-estrogen therapy by either aromatase inhibitors or selective estrogen receptor mediators such as tamoxifen. Nevertheless, acquired resistance to tamoxifen under treatment frequently hampers therapy. One proposed explanation for this phenomenon is the interaction of the tumor cells with cells ... Read more >>

Virchows Arch (Virchows Archiv : an international journal of pathology)
[2022, 480(3):529-541]

Cited: 0 times

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Carcinoma-Associated Fibroblasts Promote Growth of Sox2-Expressing Breast Cancer Cells.

Angela Dittmer, Jürgen Dittmer,

CAFs (Carcinoma-associated fibroblasts) play an important role in cancer progression. For instance, they promote resistance to anti-estrogens, such as fulvestrant. Here, we show that, in ERα-positive breast cancer cell lines, the cocktail of factors secreted by CAFs (CAF-CM) induce the expression of the embryonal stem cell transcription factor Sox2 (sex ... Read more >>

Cancers (Basel) (Cancers)
[2020, 12(11):E3435]

Cited: 3 times

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