Full Text Journal Articles by
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FIGO good practice recommendations for reducing preterm birth and improving child outcomes.

Bo Jacobsson, Joe Leigh Simpson, ,

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):1-4]

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FIGO good practice recommendations on cervical cerclage for prevention of preterm birth.

Andrew Shennan, Lisa Story, Bo Jacobsson, William A Grobman, ,

Cervical cerclage is an intervention which when given to the right women can prevent preterm birth and second-trimester fetal losses. A history-indicated cerclage should be offered to women who have had three or more preterm deliveries and/or mid-trimester losses. An ultrasound-indicated cerclage should be offered to women with a cervical ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):19-22]

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FIGO good practice recommendations on progestogens for prevention of preterm delivery.

Andrew Shennan, Natalie Suff, Joe Leigh Simpson, Bo Jacobsson, Ben W Mol, William A Grobman, ,

Women at high risk of preterm birth (either a previous spontaneous preterm birth and/or sonographic short cervix) with a singleton gestation should be offered daily vaginal progesterone or weekly 17-OHPC treatment to prevent preterm birth. Benefit is most significant in those with prior history of preterm birth and a short ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):16-18]

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FIGO good practice recommendations on the use of pessary for reducing the frequency and improving outcomes of preterm birth.

William A Grobman, Jane Norman, Bo Jacobsson, ,

A pessary is a device made of synthetic material that is placed in the vagina and has been used for prevention of preterm birth. It has been suggested that a potential mechanism of the pessary is alteration of the cervico-uterine angle to a more posterior position, which reduces cervical compression ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):23-25]

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FIGO good practice recommendations on the importance of registry data for monitoring rates and health systems performance in prevention and management of preterm birth.

J Frederik Frøen, Ana Bianchi, Ann-Beth Moller, Bo Jacobsson, ,

FIGO calls for strengthening of health information systems for reproductive, maternal, newborn, and child health services, co-designed with users, to ensure the timely accessibility of actionable high-quality data for all stakeholders engaged in preventing and managing preterm birth consequences. FIGO calls for strengthening of investments and capacity for implementing digital ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):5-7]

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FIGO good practice recommendations on reduction of preterm birth in pregnancies conceived by assisted reproductive technologies.

Ben W Mol, Bo Jacobsson, William A Grobman, Kelle Moley, ,

FIGO (the International Federation of Gynecology and Obstetrics) supports assisted reproductive technologies (ART) to achieve pregnancy and supports their availability in all nations. However, the increased frequency of preterm birth must be taken into account. Therefore, before in vitro fertilization (IVF) is started, other approaches, including expectant management, should be ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):13-15]

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FIGO good practice recommendations on the use of prenatal corticosteroids to improve outcomes and minimize harm in babies born preterm.

Jane Norman, Andrew Shennan, Bo Jacobsson, Sarah J Stock, ,

For women with a singleton or a multiple pregnancy in situations where active neonatal care is appropriate, and for whom preterm birth is anticipated between 24 and 34 weeks of gestation, one course of prenatal corticosteroids should ideally be offered 18 to 72 h before preterm birth is expected to improve outcomes ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):26-30]

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Validation of the BPro radial pulse waveform acquisition device in pregnancy and gestational hypertensive disorders.

Adam Jakes, Julie Wade, Zoe Vowles, Paul T Seed, Andrew H Shennan, Lucy C Chappell, Diane Nzelu,

<h4>Objective</h4>To validate the BPro blood pressure (BP) wrist device for use in pregnancy and preeclampsia according to the Universal Standard protocol.<h4>Participants and methods</h4>BP was measured sequentially in 45 pregnant women (including 15 with preeclampsia, 15 with gestational hypertension and 15 who remained normotensive) alternating between a mercury sphygmomanometer and BPro ... Read more >>

Blood Press Monit (Blood pressure monitoring)
[2021, 26(5):380-384]

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FIGO good practice recommendations on delayed umbilical cord clamping.

Ana Bianchi, Bo Jacobsson, Ben W Mol, ,

Delayed cord clamping in the first minute in preterm infants born before 34 weeks of gestation improves neonatal hematologic measures and may reduce mortality without increasing any other morbidity. In term-born babies, it also seems to improve both the short- and long-term outcomes and shows favorable scores in fine motor and ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):34-36]

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FIGO good practice recommendations on modifiable causes of iatrogenic preterm birth.

Catalina M Valencia, Ben W Mol, Bo Jacobsson, ,

Iatrogenic preterm birth is a planned delivery that occurs before 37 weeks of gestation due to maternal and/or fetal causes. However, in some cases, such deliveries also occur with no apparent medical indication. The increasing numbers of iatrogenic preterm deliveries worldwide have led researchers to identify modifiable causes that allow the ... Read more >>

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 155(1):8-12]

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Cervicovaginal microbiota and metabolome predict preterm birth risk in an ethnically diverse cohort.

Flavia Flaviani, Natasha L Hezelgrave, Tokuwa Kanno, Erica M Prosdocimi, Evonne Chin-Smith, Alexandra E Ridout, Djuna K von Maydell, Vikash Mistry, William G Wade, Andrew H Shennan, Konstantina Dimitrakopoulou, Paul T Seed, A James Mason, Rachel M Tribe,

The syndrome of spontaneous preterm birth (sPTB) presents a challenge to mechanistic understanding, effective risk stratification, and clinical management. Individual associations between sPTB, self-reported ethnic ancestry, vaginal microbiota, metabolome, and innate immune response are known but not fully understood, and knowledge has yet to impact clinical practice. Here, we used ... Read more >>

JCI Insight (JCI insight)
[2021, 6(16):]

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A prognostic model, including quantitative fetal fibronectin, to predict preterm labour: the QUIDS meta-analysis and prospective cohort study.

Sarah J Stock, Margaret Horne, Merel Bruijn, Helen White, Robert Heggie, Lisa Wotherspoon, Kathleen Boyd, Lorna Aucott, Rachel K Morris, Jon Dorling, Lesley Jackson, Manju Chandiramani, Anna David, Asma Khalil, Andrew Shennan, Gert-Jan van Baaren, Victoria Hodgetts-Morton, Tina Lavender, Ewoud Schuit, Susan Harper-Clarke, Ben Mol, Richard D Riley, Jane Norman, John Norrie,

<h4>Background</h4>The diagnosis of preterm labour is challenging. False-positive diagnoses are common and result in unnecessary, potentially harmful treatments (e.g. tocolytics, antenatal corticosteroids and magnesium sulphate) and costly hospital admissions. Measurement of fetal fibronectin in vaginal fluid is a biochemical test that can indicate impending preterm birth.<h4>Objectives</h4>To develop an externally validated ... Read more >>

Health Technol Assess (Health technology assessment (Winchester, England))
[2021, 25(52):1-168]

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Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension.

Gianfranco Parati, George S Stergiou, Grzegorz Bilo, Anastasios Kollias, Martino Pengo, Juan Eugenio Ochoa, Rajiv Agarwal, Kei Asayama, Roland Asmar, Michel Burnier, Alejandro De La Sierra, Cristina Giannattasio, Philippe Gosse, Geoffrey Head, Satoshi Hoshide, Yutaka Imai, Kazuomi Kario, Yan Li, Efstathios Manios, Jonathan Mant, Richard J McManus, Thomas Mengden, Anastasia S Mihailidou, Paul Muntner, Martin Myers, Teemu Niiranen, Angeliki Ntineri, Eoin O'Brien, José Andres Octavio, Takayoshi Ohkubo, Stefano Omboni, Paul Padfield, Paolo Palatini, Dario Pellegrini, Nicolas Postel-Vinay, Agustin J Ramirez, James E Sharman, Andrew Shennan, Egle Silva, Jirar Topouchian, Camilla Torlasco, Ji Guang Wang, Michael A Weber, Paul K Whelton, William B White, Giuseppe Mancia, ,

The present paper provides an update of previous recommendations on Home Blood Pressure Monitoring from the European Society of Hypertension (ESH) Working Group on Blood Pressure Monitoring and Cardiovascular Variability sequentially published in years 2000, 2008 and 2010. This update has taken into account new evidence in this field, including ... Read more >>

J Hypertens (Journal of hypertension)
[2021, 39(9):1742-1767]

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Multicenter Cohort Study, With a Nested Randomized Comparison, to Examine the Cardiovascular Impact of Preterm Preeclampsia.

Fergus P McCarthy, Jamie M O'Driscoll, Paul T Seed, Anna Placzek, Carolyn Gill, Jenie Sparkes, Lucilla Poston, Mike Marber, Andrew H Shennan, Basky Thilaganathan, Paul Leeson, Lucy C Chappell,

This study evaluated whether planned early delivery would ameliorate cardiovascular dysfunction 6 months postpartum, compared with usual care with expectant management, in women with late preterm preeclampsia. We conducted a mechanistic observational study in women with preterm preeclampsia between 34<sup>+0</sup> and 36<sup>+6</sup> weeks' gestation, nested within a randomized controlled trial ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2021, :HYPERTENSIONAHA12117171]

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Erratum: Randomized Trials of Retosiban versus Placebo or Atosiban in Spontaneous Preterm Labor.

George Saade, Andrew Shennan, Kathleen J Beach, Eran Hadar, Barbara V Parilla, Jerry Snidow, Marcy Powell, Timothy H Montague, Feng Liu, Yosuke Komatsu, Laura McKain, Steven Thornton,

Am J Perinatol (American journal of perinatology)
[2021, 38(S 01):e370]

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Development and validation of a risk prediction model of preterm birth for women with preterm labour symptoms (the QUIDS study): A prospective cohort study and individual participant data meta-analysis.

Sarah J Stock, Margaret Horne, Merel Bruijn, Helen White, Kathleen A Boyd, Robert Heggie, Lisa Wotherspoon, Lorna Aucott, Rachel K Morris, Jon Dorling, Lesley Jackson, Manju Chandiramani, Anna L David, Asma Khalil, Andrew Shennan, Gert-Jan van Baaren, Victoria Hodgetts-Morton, Tina Lavender, Ewoud Schuit, Susan Harper-Clarke, Ben W Mol, Richard D Riley, Jane E Norman, John Norrie,

<h4>Background</h4>Timely interventions in women presenting with preterm labour can substantially improve health outcomes for preterm babies. However, establishing such a diagnosis is very challenging, as signs and symptoms of preterm labour are common and can be nonspecific. We aimed to develop and externally validate a risk prediction model using concentration ... Read more >>

PLoS Med (PLoS medicine)
[2021, 18(7):e1003686]

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Blood pressure thresholds in pregnancy for identifying maternal and infant risk: a secondary analysis of Community-Level Interventions for Pre-eclampsia (CLIP) trial data.

Jeffrey N Bone, Laura A Magee, Joel Singer, Hannah Nathan, Rahat N Qureshi, Charfudin Sacoor, Esperança Sevene, Andrew Shennan, Mrutyunjaya B Bellad, Shivaprasad S Goudar, Ashalata A Mallapur, Khátia Munguambe, Marianne Vidler, Zulfiqar A Bhutta, Peter von Dadelszen, ,

<h4>Background</h4>Blood pressure measurement is a marker of antenatal care quality. In well resourced settings, lower blood pressure cutoffs for hypertension are associated with adverse pregnancy outcomes. We aimed to study the associations between blood pressure thresholds and adverse outcomes and the diagnostic test properties of these blood pressure cutoffs in ... Read more >>

Lancet Glob Health (The Lancet. Global health)
[2021, 9(8):e1119-e1128]

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A literature review and best practice advice for second and third trimester risk stratification, monitoring, and management of pre-eclampsia: Compiled by the Pregnancy and Non-Communicable Diseases Committee of FIGO (the International Federation of Gynecology and Obstetrics).

Liona C Poon, Laura A Magee, Stefan Verlohren, Andrew Shennan, Peter von Dadelszen, Eyal Sheiner, Eran Hadar, Gerard Visser, Fabricio Da Silva Costa, Anil Kapur, Fionnuala McAuliffe, Amala Nazareth, Muna Tahlak, Anne B Kihara, Hema Divakar, H David McIntyre, Vincenzo Berghella, Huixia Yang, Roberto Romero, Kypros H Nicolaides, Nir Melamed, Moshe Hod,

Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
[2021, 154 Suppl 1:3-31]

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The Arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: the STOPPIT 2 RCT.

Jane E Norman, John Norrie, Graeme MacLennan, David Cooper, Sonia Whyte, Sushila Chowdhry, Sarah Cunningham-Burley, Aileen R Neilson, Xue W Mei, Joel Be Smith, Andrew Shennan, Stephen C Robson, Steven Thornton, Mark D Kilby, Neil Marlow, Sarah J Stock, Philip R Bennett, Jane Denton,

<h4>Background</h4>Preterm birth is common in twins and accounts for significant mortality and morbidity. There are no effective preventative treatments. Some studies have suggested that, in twin pregnancy complicated by a short cervix, the Arabin pessary, which fits around the cervix and can be inserted as an outpatient procedure, reduces preterm ... Read more >>

Health Technol Assess (Health technology assessment (Winchester, England))
[2021, 25(44):1-66]

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Evaluating the use of the QUiPP app and its impact on the management of threatened preterm labour: A cluster randomised trial.

Helena A Watson, Naomi Carlisle, Paul T Seed, Jenny Carter, Katy Kuhrt, Rachel M Tribe, Andrew H Shennan,

<h4>Background</h4>Preterm delivery (before 37 weeks of gestation) is the single most important contributor to neonatal death and morbidity, with lifelong repercussions. However, the majority of women who present with preterm labour (PTL) symptoms do not deliver imminently. Accurate prediction of PTL is needed in order ensure correct management of those ... Read more >>

PLoS Med (PLoS medicine)
[2021, 18(7):e1003689]

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Planned early delivery for late preterm pre-eclampsia in a low- and middle-income setting: a feasibility study.

Alice Beardmore-Gray, Nicola Vousden, Sergio A Silverio, Umesh Charantimath, Geetanjali Katageri, Mrutyunjaya Bellad, Sebastian Chinkoyo, Bellington Vwalika, Shivaprasad Goudar, Jane Sandall, Lucy C Chappell, Andrew H Shennan,

<h4>Background</h4>Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity globally. Planned delivery between 34<sup>+0</sup> and 36<sup>+6</sup> weeks may reduce adverse pregnancy outcomes but is yet to be evaluated in a low and middle-income setting. Prior to designing a randomised controlled trial to evaluate this in India and Zambia, ... Read more >>

Reprod Health (Reproductive health)
[2021, 18(1):110]

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Maternal and fetal incidental findings on antenatal magnetic resonance imaging.

Lisa Story, Caroline L Knight, Alison Ho, Sophie Arulkumaran, Jacqueline Matthews, Holly Lovell, Laura McCabe, Megan Byrne, Alexia Egloff, Audrey E T Jacques, Jim Carmichael, Jo Hajnal, Andrew Shennan, Mary Rutherford,

<h4>Background</h4>Magnetic resonance imaging (MRI) examinations are increasingly used in antenatal clinical practice. Incidental findings are a recognized association with imaging and although in some circumstances their identification can alter management, they are often associated with increased anxiety, for both patient and clinician, as well as increased health care costs.<h4>Objective</h4>This study ... Read more >>

Pediatr Radiol (Pediatric radiology)
[2021, 51(10):1839-1847]

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The ability and safety of community-based health workers to safely initiate lifesaving therapies for pre-eclampsia in Ogun State, Nigeria: An analysis of 260 community treatments with MgSO4 and/or methyldopa.

Akinmade A Adepoju, Marianne Vidler, Adebayo A Akadri, Ebun Jaiyesimi, Chimaobi C Nwankpa, Oluwafayokemi O Odubena, Sumedha Sharma, Larry Li, Domena Tu, Sharla Drebit, Beth Payne, David O Akeju, Zulfiqar Bhutta, Laura A Magee, Hannah L Nathan, Andrew H Shennan, John Sotunsa, Olalekan O Adetoro, Peter von Dadelszen, Olukayode A Dada, Olaokun Soyinka, ,

<h4>Objectives</h4>To evaluate community-based health workers' ability to identify cases of hypertension in pregnancy, safely deliver methyldopa and magnesium sulphate and make referrals when appropriate.<h4>Study design</h4>This was part of Nigeria Community-Level Interventions for Pre-eclampsia (CLIP) cluster randomized controlled trial (NCT01911494). Community-based Health Workers (CHW) recruited pregnant women from five Local Government ... Read more >>

Pregnancy Hypertens (Pregnancy hypertension)
[2021, 25:179-184]

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A prognostic model to guide decision-making on timing of delivery in late preterm pre-eclampsia: the PEACOCK prospective cohort study.

Kate Duhig, Paul T Seed, Anna Placzek, Jenie Sparkes, Carolyn Gill, Anna Brockbank, Andrew Shennan, Shakila Thangaratinam, Lucy C Chappell,

<h4>Background</h4>Pre-eclampsia affects around 2-3% of all pregnancies, and is associated with potential serious complications for the woman and the baby. Once diagnosed, progression of the syndrome can be unpredictable, and decisions around timing of delivery need to take into account evolving maternal complications and perinatal morbidity. Novel prognostic models and ... Read more >>

Health Technol Assess (Health technology assessment (Winchester, England))
[2021, 25(30):1-32]

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Development and rapid rollout of The QUiPP App Toolkit for women who arrive in threatened preterm labour.

Naomi Carlisle, Helena A Watson, Andrew H Shennan,

<h4>Background</h4>Often the first opportunity for clinicians to assess risk of preterm birth is when women present with threatened preterm labour symptoms (such as period-like pain, tightening's or back ache). However, threatened preterm labour symptoms are not a strong predictor of imminent birth. Clinicians are then faced with a complex clinical ... Read more >>

BMJ Open Qual (BMJ open quality)
[2021, 10(2):]

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