Full Text Journal Articles by
Author Andrew Georgiou

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Variation in electronic test results management and its implications for patient safety: A multisite investigation.

Judith Thomas, Maria R Dahm, Julie Li, Peter Smith, Jacqui Irvine, Johanna I Westbrook, Andrew Georgiou,

OBJECTIVE:The management and follow-up of diagnostic test results is a major patient safety concern. The aim of this qualitative study was to explore how clinicians manage test results on an everyday basis (work-as-done) in a health information technology-enabled emergency department setting. The objectives were to identify (1) variations in work-as-done ... Read more >>

J Am Med Inform Assoc (Journal of the American Medical Informatics Association : JAMIA)
[2020, :]

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Barriers to patient, provider, and caregiver adoption and use of electronic personal health records in chronic care: a systematic review.

Zahra Niazkhani, Esmaeel Toni, Mojgan Cheshmekaboodi, Andrew Georgiou, Habibollah Pirnejad,

BACKGROUND:Electronic personal health records (ePHRs) are defined as electronic applications through which individuals can access, manage, and share health information in a private, secure, and confidential environment. Existing evidence shows their benefits in improving outcomes, especially for chronic disease patients. However, their use has not been as widespread as expected ... Read more >>

BMC Med Inform Decis Mak (BMC medical informatics and decision making)
[2020, 20(1):153]

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Social Participation Among Older Adults Receiving Community Care Services.

Joyce Siette, Helen Berry, Mikaela Jorgensen, Lindsey Brett, Andrew Georgiou, Tom McClean, Johanna Westbrook,

Aged care services have the potential to support social participation for the growing number of adults aging at home, but little is known about the types of social activities older adults in community care are engaged in. We used cluster analysis to examine the current profiles of social participation across ... Read more >>

J Appl Gerontol (Journal of applied gerontology : the official journal of the Southern Gerontological Society)
[2020, :733464820938973]

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Publisher Correction: A clonal expression biomarker associates with lung cancer mortality.

Dhruva Biswas, Nicolai J Birkbak, Rachel Rosenthal, Crispin T Hiley, Emilia L Lim, Krisztian Papp, Stefan Boeing, Marcin Krzystanek, Dijana Djureinovic, Linnea La Fleur, Maria Greco, Balázs Döme, János Fillinger, Hans Brunnström, Yin Wu, David A Moore, Marcin Skrzypski, Christopher Abbosh, Kevin Litchfield, Maise Al Bakir, Thomas B K Watkins, Selvaraju Veeriah, Gareth A Wilson, Mariam Jamal-Hanjani, Judit Moldvay, Johan Botling, Arul M Chinnaiyan, Patrick Micke, Allan Hackshaw, Jiri Bartek, Istvan Csabai, Zoltan Szallasi, Javier Herrero, Nicholas McGranahan, Charles Swanton, ,

An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Nat. Med. (Nature medicine)
[2020, 26(7):1148]

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Barriers to patient, provider, and caregiver adoption and use of electronic personal health records in chronic care: a systematic review 

Zahra Niazkhani, Esmaeel Toni, Mojgan Cheshmekaboodi, Andrew Georgiou, Habibollah Pirnejad,

Abstract Background: Electronic personal health records (ePHRs) are defined as electronic applications through which individuals can access, manage, and share health information in a private, secure, and confidential environment. Existing evidence shows their benefits in improving outcomes, especially for chronic disease patients. However, their use has not been as widespread ... Read more >>

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Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.

Kroopa Joshi, Marc Robert de Massy, Mazlina Ismail, James L Reading, Imran Uddin, Annemarie Woolston, Emine Hatipoglu, Theres Oakes, Rachel Rosenthal, Thomas Peacock, Tahel Ronel, Mahdad Noursadeghi, Virginia Turati, Andrew J S Furness, Andrew Georgiou, Yien Ning Sophia Wong, Assma Ben Aissa, Mariana Werner Sunderland, Mariam Jamal-Hanjani, Selvaraju Veeriah, Nicolai J Birkbak, Gareth A Wilson, Crispin T Hiley, Ehsan Ghorani, José Afonso Guerra-Assunção, Javier Herrero, Tariq Enver, Sine R Hadrup, Allan Hackshaw, Karl S Peggs, Nicholas McGranahan, Charles Swanton, , Sergio A Quezada, Benny Chain,

An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Nat. Med. (Nature medicine)
[2020, 26(7):1148]

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Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.

Francesca Chemi, Dominic G Rothwell, Nicholas McGranahan, Sakshi Gulati, Chris Abbosh, Simon P Pearce, Cong Zhou, Gareth A Wilson, Mariam Jamal-Hanjani, Nicolai Birkbak, Jackie Pierce, Chang Sik Kim, Saba Ferdous, Deborah J Burt, Daniel Slane-Tan, Fabio Gomes, David Moore, Rajesh Shah, Maise Al Bakir, Crispin Hiley, Selvaraju Veeriah, Yvonne Summers, Philip Crosbie, Sophia Ward, Barbara Mesquita, Marek Dynowski, Dhruva Biswas, Jonathan Tugwood, Fiona Blackhall, Crispin Miller, Allan Hackshaw, Ged Brady, Charles Swanton, Caroline Dive, ,

An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Read more >>

Nat. Med. (Nature medicine)
[2020, 26(7):1147]

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Barriers to patient, provider, and caregiver adoption and use of electronic personal health records in chronic care: a systematic review

Zahra Niazkhani, Esmaeel Toni, Mojgan Cheshmekaboodi, Andrew Georgiou, Habibollah Pirnejad,

Abstract Background Electronic personal health records (ePHRs) are defined as electronic applications through which individuals can access, manage, and share health information in a private, secure, and confidential environment. Existing evidence shows their benefits in improving outcomes, especially for chronic disease patients. However, their use has not been as widespread ... Read more >>

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Does health information technology improve acknowledgement of radiology results for discharged Emergency Department patients? A before and after study.

Julie Li, Richard Paoloni, Ling Li, Joanne Callen, Johanna I Westbrook, William B Runciman, Andrew Georgiou,

BACKGROUND:The inadequate follow-up of test results is a key patient safety concern, carrying severe consequences for care outcomes. Patients discharged from the emergency department are at particular risk of having test results pending at discharge due to their short lengths of stay, with many hospitals acknowledging that they do not ... Read more >>

BMC Med Inform Decis Mak (BMC medical informatics and decision making)
[2020, 20(1):100]

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Social networks and cognitive function in older adults receiving home- and community-based aged care.

Joyce Siette, Andrew Georgiou, Carol Brayne, Johanna I Westbrook,

OBJECTIVES:Social engagement has been linked to preserved cognitive functioning in later life. Yet, little is known about the specific network factors that best predict cognitive function in older adults. This study aimed to (i) characterize the quality and quantity of interpersonal relationships and (ii) explore the relationship between social network ... Read more >>

Arch Gerontol Geriatr (Archives of gerontology and geriatrics)
[2020, 89:104083]

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Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.

Khalid AbdulJabbar, Shan E Ahmed Raza, Rachel Rosenthal, Mariam Jamal-Hanjani, Selvaraju Veeriah, Ayse Akarca, Tom Lund, David A Moore, Roberto Salgado, Maise Al Bakir, Luis Zapata, Crispin T Hiley, Leah Officer, Marco Sereno, Claire Rachel Smith, Sherene Loi, Allan Hackshaw, Teresa Marafioti, Sergio A Quezada, Nicholas McGranahan, John Le Quesne, , Charles Swanton, Yinyin Yuan,

Remarkable progress in molecular analyses has improved our understanding of the evolution of cancer cells toward immune escape1-5. However, the spatial configurations of immune and stromal cells, which may shed light on the evolution of immune escape across tumor geographical locations, remain unaddressed. We integrated multiregion exome and RNA-sequencing (RNA-seq) ... Read more >>

Nat. Med. (Nature medicine)
[2020, 26(7):1054-1062]

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Harnessing the potential of electronic general practice pathology data in Australia: An examination of the quality use of pathology for type 2 diabetes patients.

Chisato Imai, Rae-Anne Hardie, Guilherme Saffi Franco, Gorkem Sezgin, Kathy Tepper, Adam McLeod, Christopher Pearce, Johanna Westbrook, Andrew Georgiou,

BACKGROUND:Despite the importance of pathology testing in diagnosis and disease monitoring, there is little in-depth research about pathology test ordering in general practice and how it impacts patient outcomes. This is in part due to the limited availability of high-quality data. With the now-widespread use of electronic software in general ... Read more >>

Int J Med Inform (International journal of medical informatics)
[2020, 141:104189]

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Improving Patients' Medication Adherence and Outcomes in Non-Hospital Settings through eHealth: A Systematic Review of Randomized Controlled Trials.

Zoie Sy Wong, Braylien Siy, Katharina Da Silva Lopes, Andrew Georgiou,

BACKGROUND:eHealth refers to the use of information and communication technologies (ICT) for health. It plays an increasingly important role in patients' medication management. OBJECTIVE:To assess evidence on (1) whether eHealth for patients' medication management can improve drug adherence and health outcomes in non-hospital settings and (2) which eHealth functions are ... Read more >>

J. Med. Internet Res. (Journal of medical Internet research)
[2020, :]

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Exploring information technology (IT) sophistication in New South Wales residential aged care facilities.

Gregory L Alexander, Andrew Georgiou, Joyce Siette, Richard Madsen, Anne Livingstone, Johanna Westbrook, Chelsea Deroche,

Objective The aim of this study was to determine baseline information technology (IT) sophistication in New South Wales (NSW), Australia, residential aged care facilities. Method IT sophistication measures IT capabilities, extent of IT use and IT integration in two domains, resident care and clinical support. A survey was administered to ... Read more >>

Aust Health Rev (Australian health review : a publication of the Australian Hospital Association)
[2020, 44(2):288-296]

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Managing Uncertainty During the Communication of Diagnostic Test Information Between Patients and Clinicians in Australian Emergency Care.

Melissa Miao, Maria R Dahm, Julie Li, Judith Thomas, Andrew Georgiou,

We sought (a) an inductive understanding of patient and clinician perspectives and experiences of the communication of diagnostic test information and (b) a normative understanding of the management of uncertainty that occurs during the clinical encounter in emergency care. Between 2016 and 2018, 58 interviews were conducted with patients and ... Read more >>

Qual Health Res (Qualitative health research)
[2020, 30(8):1287-1300]

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Differentiating Experience From Cue Utilization in Radiological Assessments.

Ann J Carrigan, John Magnussen, Andrew Georgiou, Kim M Curby, Thomas J Palmeri, Mark W Wiggins,

OBJECTIVE:This research was designed to examine the contribution of self-reported experience and cue utilization to diagnostic accuracy in the context of radiology. BACKGROUND:Within radiology, it is unclear how task-related experience contributes to the acquisition of associations between features with events in memory, or cues, and how they contribute to diagnostic ... Read more >>

Hum Factors (Human factors)
[2020, :18720820902576]

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Under-detection of acute kidney injury in hospitalised patients: a retrospective, multi-site, longitudinal study.

Craig A Campbell, Ling Li, Sradha Kotwal, Andrew Georgiou, Andrea R Horvath, Johanna Westbrook, Zoltan Endre,

BACKGROUND:Acute kidney injury (AKI) is a rapid deterioration of renal function, often caused by a variety of co-existing morbidities complicating its recognition and treatment, leading to short- and long-term adverse clinical outcomes. There are limited data on the incidence of AKI in Australia using the Kidney Disease Improving Global Outcomes ... Read more >>

Intern Med J (Internal medicine journal)
[2020, 50(3):307-314]

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Advancing health information technology roadmaps in long term care.

Gregory L Alexander, Andrew Georgiou, Kevin Doughty, Andrew Hornblow, Anne Livingstone, Michelle Dougherty, Stephen Jacobs, Malcolm J Fisk,

BACKGROUND:Our purpose is to provide evidence that health information technology should be a mainstay of all future health and social support services for older people globally, both within and across community and residential care services. METHODS:This work was conducted in two phases. In phase I, the authors conducted a focused ... Read more >>

Int J Med Inform (International journal of medical informatics)
[2020, 136:104088]

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Measuring the prevalence of 60 health conditions in older Australians in residential aged care with electronic health records: a retrospective dynamic cohort study

Kimberly Lind, Magdalena Raban, Lindsey Brett, Mikaela Jorgensen, Andrew Georgiou, Johanna Westbrook,

Abstract Background : The number of older Australians using aged care services is increasing, yet there is an absence of reliable data on their health. Multimorbidity in this population has not been well described. A clear picture of the health status of people using aged care is essential for informing ... Read more >>

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The effect of home care package allocation reforms on service uptake, use and cessation at a large Australian aged care provider.

Mikaela Jorgensen, Joyce Siette, Andrew Georgiou, Johanna I Westbrook,

OBJECTIVE:To utilise routinely collected data to examine changes in the client profile of a large aged care provider before and after commencement of the 2017 policy reforms, whereby home care packages were allocated to individuals rather than providers. METHODS:Interrupted time series analysis was used to measure changes in service uptake ... Read more >>

Australas J Ageing (Australasian journal on ageing)
[2020, 39(2):e210-e214]

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A comparative study of the utilisation of an electronic test-result management system in emergency and intensive care settings.

Judith Thomas, Maria R Dahm, Julie Li, Johanna I Westbrook, Andrew Georgiou,

The purpose of this qualitative study was to identify differences in the utilisation of an electronic medical record test-result management system between two acute care departments. Field observations (130 min) and semi-structured interviews (n = 24) were conducted in the Intensive Care Unit and Emergency Department of an Australian hospital. Work processes identified ... Read more >>

Health Informatics J (Health informatics journal)
[2019, :1460458219889223]

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At the grassroots of home and community-based aged care: strategies for successful consumer engagement.

Lindsey Brett, Joyce Siette, Amy Nguyen, Mikaela Jorgensen, Melissa Miao, Johanna Westbrook, Winifred Lee, Edwina Gow, Fleur Hourihan, Andrew Georgiou,

OBJECTIVES:(1) To describe the processes used to plan and conduct a stakeholder forum in aged care as a means of informing future uptake of consumer participatory research. (2) To discuss how capturing and drawing on stakeholders' experiences of aged care can generate new research ideas and inform the delivery of ... Read more >>

BMJ Open (BMJ open)
[2019, 9(11):e028754]

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Interaction and innovation: practical strategies for inclusive consumer-driven research in health services.

Maria R Dahm, Anthony Brown, Dean Martin, Maureen Williams, Brian Osborne, Jocelyne Basseal, Mary Potter, Rae-Anne Hardie, Julie Li, Judith Thomas, Andrew Georgiou,

INTRODUCTION:Despite advances in the co-creation of clinical research involving consumers in the last few decades, consumer engagement in health services research generally remains inconsistent and is too often treated as a perfunctory exercise. OBJECTIVE:Drawing on a health services study on diagnostic test result management, communication and follow-up, we: (1) outline ... Read more >>

BMJ Open (BMJ open)
[2019, 9(12):e031555]

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Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse.

Francesca Chemi, Dominic G Rothwell, Nicholas McGranahan, Sakshi Gulati, Chris Abbosh, Simon P Pearce, Cong Zhou, Gareth A Wilson, Mariam Jamal-Hanjani, Nicolai Birkbak, Jackie Pierce, Chang Sik Kim, Saba Ferdous, Deborah J Burt, Daniel Slane-Tan, Fabio Gomes, David Moore, Rajesh Shah, Maise Al Bakir, Crispin Hiley, Selvaraju Veeriah, Yvonne Summers, Philip Crosbie, Sophia Ward, Barbara Mesquita, Marek Dynowski, Dhruva Biswas, Jonathan Tugwood, Fiona Blackhall, Crispin Miller, Allan Hackshaw, Ged Brady, Charles Swanton, Caroline Dive, ,

Approximately 50% of patients with early-stage non-small-cell lung cancer (NSCLC) who undergo surgery with curative intent will relapse within 5 years1,2. Detection of circulating tumor cells (CTCs) at the time of surgery may represent a tool to identify patients at higher risk of recurrence for whom more frequent monitoring is ... Read more >>

Nat. Med. (Nature medicine)
[2019, 25(10):1534-1539]

Cited: 5 times

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A clonal expression biomarker associates with lung cancer mortality.

Dhruva Biswas, Nicolai J Birkbak, Rachel Rosenthal, Crispin T Hiley, Emilia L Lim, Krisztian Papp, Stefan Boeing, Marcin Krzystanek, Dijana Djureinovic, Linnea La Fleur, Maria Greco, Balázs Döme, János Fillinger, Hans Brunnström, Yin Wu, David A Moore, Marcin Skrzypski, Christopher Abbosh, Kevin Litchfield, Maise Al Bakir, Thomas B K Watkins, Selvaraju Veeriah, Gareth A Wilson, Mariam Jamal-Hanjani, Judit Moldvay, Johan Botling, Arul M Chinnaiyan, Patrick Micke, Allan Hackshaw, Jiri Bartek, Istvan Csabai, Zoltan Szallasi, Javier Herrero, Nicholas McGranahan, Charles Swanton, ,

An aim of molecular biomarkers is to stratify patients with cancer into disease subtypes predictive of outcome, improving diagnostic precision beyond clinical descriptors such as tumor stage1. Transcriptomic intratumor heterogeneity (RNA-ITH) has been shown to confound existing expression-based biomarkers across multiple cancer types2-6. Here, we analyze multi-region whole-exome and RNA ... Read more >>

Nat. Med. (Nature medicine)
[2019, 25(10):1540-1548]

Cited: 2 times

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