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Author Andrew A Wagner

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Upstaging and Survival Outcomes for Non-Muscle Invasive Bladder Cancer After Radical Cystectomy: Results from the International Robotic Cystectomy Consortium.

Umar Iqbal, Ahmed S Elsayed, Zhe Jing, Michael Stoeckle, Carl Wijburg, Peter Wiklund, Abolfazl Hosseini, Prokar Dasgupta, Muhammad Shamim Khan, Ashok Hemal, Eric H Kim, Andrew A Wagner, Franco Gaboardi, Koon Ho Rha, Thomas Maatman, Derya Balbay, Qiang Li, Ahmed Hussein, Khurshid A Guru,

<h4>Introduction</h4>We sought to describe the incidence, risk factors, and survival outcomes associated with pathological upstaging from non-muscle invasive bladder cancer (NMIBC) to muscle invasive bladder cancer (MIBC) after robot-assisted radical cystectomy (RARC).<h4>Methods</h4>We reviewed the International Robotic Cystectomy Consortium database between 2004 and 2020. Upstaging was defined as ≥pT2 or pN+ ... Read more >>

J Endourol (Journal of endourology)
[2021, :]

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Reducing postoperative opioid pill prescribing via a quality improvement approach.

Kristian D Stensland, Peter Chang, David Jiang, David Canes, Aaron Berkenwald, Adrian Waisman, Kortney Robinson, Gabriel Brat, Catrina Crociani, Kyle Mcanally, Sarah Hyde, Brian Holliday, Jodi Mechaber, Analesa Baraka, Alireza Moinzadeh, Andrew A Wagner,

<h4>Background</h4>The opioid epidemic has been fueled by prescribing unnecessary quantities of opioid pills for postoperative use. While evidence mounts that postoperative opioids can be reduced or eliminated, implementing such changes within various institutions can be met with many barriers to adoption.<h4>Objective</h4>To address excess opioid prescribing within our institutions, we applied ... Read more >>

Int J Qual Health Care (International journal for quality in health care : journal of the International Society for Quality in Health Care)
[2021, 33(3):]

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Radical prostatectomy versus external beam radiation therapy for high-grade, clinically localized prostate cancer: Emulation of a target clinical trial.

Chanan Reitblat, Aaron Fleishman, Irving A Kaplan, Kristian D Stensland, Anthony V D'Amico, Aria F Olumi, Andrew A Wagner, Peter K Chang, Simon P Kim, Ruslan Korets, Boris Gershman,

<h4>Purpose</h4>The comparative effectiveness of surgery and radiation therapy for high-grade, clinically localized prostate cancer remains a seminal, open question in urologic oncology, with no randomized controlled trials to inform management. We therefore emulated a hypothetical target clinical trial of radical prostatectomy (RP) versus external beam radiotherapy (EBRT) for high-grade, clinically ... Read more >>

Urol Oncol (Urologic oncology)
[2021, :]

Cited: 0 times

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Results of a Randomized Phase II Trial of Intense Androgen Deprivation Therapy prior to Radical Prostatectomy in Men with High-Risk Localized Prostate Cancer.

Rana R McKay, Wanling Xie, Huihui Ye, Fiona M Fennessy, Zhenwei Zhang, Rosina Lis, Carla Calagua, Dana Rathkopf, Vincent P Laudone, Glenn J Bubley, David J Einstein, Peter K Chang, Andrew A Wagner, J Kellogg Parsons, Mark A Preston, Kerry Kilbridge, Steven L Chang, Atish D Choudhury, Mark M Pomerantz, Quoc-Dien Trinh, Adam S Kibel, Mary-Ellen Taplin,

<h4>Purpose</h4>This multicenter randomized phase 2 trial investigates the impact of intense androgen deprivation on radical prostatectomy pathologic response and radiographic and tissue biomarkers in localized prostate cancer (NCT02903368).<h4>Materials and methods</h4>Eligible patients had a Gleason score ≥4+3=7, prostate specific antigen >20 ng/mL or T3 disease and lymph nodes <20 mm. In ... Read more >>

J Urol (The Journal of urology)
[2021, 206(1):80-87]

Cited: 1 time

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Reply by Authors.

Meredith R Metcalf, Joseph G Cheaib, Michael J Biles, Hiten D Patel, Vanessa N Peña, Peter Chang, Andrew A Wagner, James M McKiernan, Phillip M Pierorazio,

J Urol (The Journal of urology)
[2021, 205(5):1293]

Cited: 0 times

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Misaligned Incentives in Benign Prostatic Enlargement Surgery: More Complex and Efficacious Procedures Are Earning Fewer Relative Value Units.

Da David Jiang, Mitchell Hayes, Kyle A Gillis, Ruslan Korets, Andrew A Wagner, Jason C Hedges, Nicholas H Chakiryan,

<b><i>Background:</i></b> Relative value units (RVUs) are the measure of value used in US Medicare reimbursement. Medicare determines physician work RVUs (wRVUs) from the Relative Value Update Committee (RUC) for a procedure based on operative time, technical skill and effort, mental effort and judgment, and stress. In theory, work RVUs should ... Read more >>

J Endourol (Journal of endourology)
[2021, 35(6):835-839]

Cited: 0 times

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Outcomes of Active Surveillance for Young Patients with Small Renal Masses: Prospective Data from the DISSRM Registry.

Meredith R Metcalf, Joseph G Cheaib, Michael J Biles, Hiten D Patel, Vanessa N Peña, Peter Chang, Andrew A Wagner, James M McKiernan, Phillip M Pierorazio,

<h4>Purpose</h4>A paradigm shift in the management of small renal masses has increased utilization of active surveillance. However, questions remain regarding safety and durability in younger patients.<h4>Materials and methods</h4>Patients aged 60 or younger at diagnosis were identified from the Delayed Intervention and Surveillance for Small Renal Masses registry. The active surveillance, ... Read more >>

J Urol (The Journal of urology)
[2021, 205(5):1286-1293]

Cited: 3 times

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Tailoring Intensity of Active Surveillance for Low-Risk Prostate Cancer Based on Individualized Prediction of Risk Stability.

Matthew R Cooperberg, Yingye Zheng, Anna V Faino, Lisa F Newcomb, Kehao Zhu, Janet E Cowan, James D Brooks, Atreya Dash, Martin E Gleave, Frances Martin, Todd M Morgan, Peter S Nelson, Ian M Thompson, Andrew A Wagner, Peter R Carroll, Daniel W Lin,

<h4>Importance</h4>Active surveillance is increasingly recognized as the preferred standard of care for men with low-risk prostate cancer. However, active surveillance requires repeated assessments, including prostate-specific antigen tests and biopsies that may increase anxiety, risk of complications, and cost.<h4>Objective</h4>To identify and validate clinical parameters that can identify men who can safely ... Read more >>

JAMA Oncol (JAMA oncology)
[2020, 6(10):e203187]

Cited: 2 times

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Portuguese version of the Expanded Prostate Cancer Index Composite for Clinical Practice (EPIC-CP): psychometric validation and prospective application for early functional outcomes at a single institution.

Danilo B Lourenço, Breno Santos Amaral, Wladimir Alfer-Junior, Ana Vasconcellos, Fernanda Russo, Rafael Sanchez-Salas, Bianca Bianco, Andrew A Wagner, Peter Chang, Marcio Covas Moschovas, Gustavo Caserta Lemos, Arie Carneiro,

<h4>Background</h4>The Expanded Prostate Index Composite for Clinical Practice (EPIC-CP) is a short version of the original EPIC, developed to facilitate the instrument's use in routine care. This study aimed to validate the EPIC-CP Portuguese version, and evaluate its role in presenting early functional outcomes of surgically treated prostate cancer patients ... Read more >>

BMC Urol (BMC urology)
[2020, 20(1):163]

Cited: 1 time

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Rates and Patterns of Recurrences and Survival Outcomes after Robot-Assisted Radical Cystectomy: Results from the International Robotic Cystectomy Consortium.

Ahmed S Elsayed, Sean Gibson, Zhe Jing, Carl Wijburg, Andrew A Wagner, Alexandre Mottrie, Prokar Dasgupta, James Peabody, Ahmed A Hussein, Khurshid A Guru,

<h4>Purpose</h4>There have been concerns about higher incidence of local and retroperitoneal recurrences after robot-assisted radical cystectomy compared to open radical cystectomy. We report and detail relapses following robot-assisted radical cystectomy using a multinational database.<h4>Materials and methods</h4>A retrospective review of the International Robotic Cystectomy Consortium was performed. Data were reviewed for ... Read more >>

J Urol (The Journal of urology)
[2021, 205(2):407-413]

Cited: 1 time

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Comparison of the Comprehensive Complication Index and Clavien-Dindo systems in predicting perioperative outcomes following radical nephroureterectomy.

Scott Geiger, Neil Kocher, Dan Illinsky, Evanguelos Xylinas, Peter Chang, Lauren Dewey, Andrew A Wagner, Firas Petros, Surena F Matin, Conrad Tobert, Chad Tracy, Pierre-Marie Patard, Mathieu Roumiguie, Leonardo Lima Monteiro, Wassim Kassouf, Jay D Raman,

<h4>Background</h4>Complications can occur following radical nephroureterectomy (RNU) in 20-40% of patients. The Comprehensive Complication Index (CCI) is an alternative grading system to the Clavien-Dindo (CD) grading system that aggregates all complications experienced by a patient on a continuous (as opposed to categorical) scale. We investigate whether the cumulative nature of ... Read more >>

Transl Androl Urol (Translational andrology and urology)
[2020, 9(4):1780-1785]

Cited: 1 time

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Patient-Reported Quality of Life and Convalescence After Minimally Invasive Kidney Cancer Surgery.

Adam B Althaus, Peter Chang, Jialin Mao, Kola Olugbade, Kimberly Taylor, Lauren Dewey, Andrew Percy, Catrina Crociani, Kyle McNally, Andrew A Wagner,

<h4>Objective</h4>To better characterize recovery after minimally invasive kidney surgery, we present a study describing patient-reported health-related quality of life (HRQOL) following minimally invasive radical nephrectomy (RN) and partial nephrectomy (PN).<h4>Methods</h4>Patients who underwent minimally invasive PN or RN for renal cancer were invited to enroll in a prospective, patient-reported HRQOL study ... Read more >>

Urology (Urology)
[2020, 144:123-129]

Cited: 1 time

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Magnetic Resonance Imaging for the Detection of High Grade Cancer in the Canary Prostate Active Surveillance Study.

Michael A Liss, Lisa F Newcomb, Yingye Zheng, Michael P Garcia, Christopher P Filson, Hilary Boyer, James D Brooks, Peter R Carroll, Matthew R Cooperberg, William J Ellis, Martin E Gleave, Frances M Martin, Todd Morgan, Peter S Nelson, Andrew A Wagner, Ian M Thompson, Daniel W Lin,

PURPOSE:We investigated the ability of prostate magnetic resonance imaging to detect Gleason Grade Group 2 or greater cancer in a standardized, multi-institutional active surveillance cohort. MATERIALS AND METHODS:We evaluated men enrolled in Canary Prostate Active Surveillance Study with Gleason Grade Group less than 2 and who underwent biopsy within 12 ... Read more >>

J Urol (The Journal of urology)
[2020, 204(4):701-706]

Cited: 4 times

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17-Gene Genomic Prostate Score Test Results in the Canary Prostate Active Surveillance Study (PASS) Cohort.

Daniel W Lin, Yingye Zheng, Jesse K McKenney, Marshall D Brown, Ruixiao Lu, Michael Crager, Hilary Boyer, Maria Tretiakova, James D Brooks, Atreya Dash, Michael D Fabrizio, Martin E Gleave, Suzanne Kolb, Michael Liss, Todd M Morgan, Ian M Thompson, Andrew A Wagner, Athanasios Tsiatis, Andrea Pingitore, Peter S Nelson, Lisa F Newcomb,

<h4>Purpose</h4>The 17-gene Onco<i>type</i> DX Genomic Prostate Score (GPS) test predicts adverse pathology (AP) in patients with low-risk prostate cancer treated with immediate surgery. We evaluated the GPS test as a predictor of outcomes in a multicenter active surveillance cohort.<h4>Materials and methods</h4>Diagnostic biopsy tissue was obtained from men enrolled at 8 ... Read more >>

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2020, 38(14):1549-1557]

Cited: 9 times

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Reply by Authors.

Jeannette M Schenk, Lisa F Newcomb, Yingye Zheng, Anna V Faino, Kehao Zhu, Yaw A Nyame, James D Brooks, Peter R Carroll, Matthew R Cooperberg, Atreya Dash, Christopher P Filson, Martin E Gleave, Michael Liss, Francis M Martin, Todd M Morgan, Peter S Nelson, Ian M Thompson, Andrew A Wagner, Daniel W Lin,

J Urol (The Journal of urology)
[2020, 203(4):733]

Cited: 0 times

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Nonlinear microscopy for detection of prostate cancer: analysis of sensitivity and specificity in radical prostatectomies.

Lucas C Cahill, Yubo Wu, Tadayuki Yoshitake, Cecilia Ponchiardi, Michael G Giacomelli, Andrew A Wagner, Seymour Rosen, James G Fujimoto,

Intraoperative evaluation of specimens during radical prostatectomy using frozen sections can be time and labor intensive. Nonlinear microscopy (NLM) is a fluorescence microscopy technique that can rapidly generate images that closely resemble H&E histology in freshly excised tissue, without requiring freezing or microtome sectioning. Specimens are stained with nuclear and ... Read more >>

Mod Pathol (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2020, 33(5):916-923]

Cited: 2 times

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The incidence, predictors, and survival of disappearing small renal masses on active surveillance.

Arnav Srivastava, Hiten D Patel, Mohit Gupta, Gregory A Joice, Zeyad Schwen, Ridwan Alam, Michael A Gorin, Michael H Johnson, Bruce J Trock, Peter Chang, Andrew A Wagner, James M McKiernan, Mohamad E Allaf, Phillip M Pierorazio,

<h4>Objective</h4>To evaluate the incidence, predictors, and survival for those small renal masses (SRM, solid mass ≤4 cm suspicious for a clinical T1a renal cell carcinoma) that disappear on imaging while undergoing active surveillance (AS).<h4>Subjects/patients and methods</h4>The Delayed Intervention and Surveillance for SRM registry prospectively enrolled 739 patients with SRMs. Patients ... Read more >>

Urol Oncol (Urologic oncology)
[2020, 38(2):42.e1-42.e6]

Cited: 0 times

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African American Race is Not Associated with Risk of Reclassification during Active Surveillance: Results from the Canary Prostate Cancer Active Surveillance Study.

Jeannette M Schenk, Lisa F Newcomb, Yingye Zheng, Anna V Faino, Kehao Zhu, Yaw A Nyame, James D Brooks, Peter R Carroll, Matthew R Cooperberg, Atreya Dash, Christopher P Filson, Martin E Gleave, Michael Liss, Francis M Martin, Todd M Morgan, Peter S Nelson, Ian M Thompson, Andrew A Wagner, Daniel W Lin,

<h4>Purpose</h4>In a large, prospective, multi-institutional active surveillance cohort we evaluated whether African American men are at higher risk for reclassification.<h4>Materials and methods</h4>The Canary PASS (Prostate Active Surveillance Study) is a protocol driven, active surveillance cohort with a prespecified prostate specific antigen and surveillance biopsy regimen. Men included in this study ... Read more >>

J Urol (The Journal of urology)
[2020, 203(4):727-733]

Cited: 5 times

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AUTHOR REPLY.

Joan C Delto, Peter Chang, Sara Hyde, Kyle McAnally, Catrina Crociani, Andrew A Wagner,

Urology (Urology)
[2019, 132:135]

Cited: 0 times

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Neoadjuvant Chemotherapy is Not Associated with Adverse Perioperative Outcomes after Robot-Assisted Radical Cystectomy: A Case for Increased Use from the IRCC.

Naif A Aldhaam, Ahmed S Elsayed, Zhe Jing, Lee Richstone, Andrew A Wagner, Koon Ho Rha, Bertram Yuh, Juan Palou, Muhammad Shamim Khan, Mani Menon, Morgan Roupret, Derya Balbay, Abolfazl Hosseini, Peter Wiklund, Franco Gaboardi, Thomas J Maatman, Alexandre Mottrie, Carl Wijburg, Michael Stöckle, Ashok Hemal, Eric Kim, Jihad Kaouk, Ahmed A Hussein, Khurshid A Guru,

<h4>Purpose</h4>We sought to determine the trend of neoadjuvant chemotherapy use for nonmetastatic muscle invasive urothelial bladder cancer and whether it is associated with adverse perioperative morbidity after robot-assisted radical cystectomy.<h4>Materials and methods</h4>We retrospectively reviewed the IRCC (International Robotic Cystectomy Consortium) database between 2006 and 2017. After excluding patients with nonmuscle ... Read more >>

J Urol (The Journal of urology)
[2020, 203(1):57-61]

Cited: 1 time

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Reducing Pseudoaneurysm and Urine Leak After Robotic Partial Nephrectomy: Results Using the Early Unclamping Technique.

Joan C Delto, Peter Chang, Sara Hyde, Kyle McAnally, Catrina Crociani, Andrew A Wagner,

OBJECTIVE:To present our experience using the early unclamping technique for robotic partial nephrectomy with particular attention to delayed complications, namely pseudoaneurysm and urine leak. We hypothesized that early hilar unclamping allows for improved control of end arteries and renorrhaphy after tumor resection, reducing overall delayed complications after partial nephrectomy with ... Read more >>

Urology (Urology)
[2019, 132:130-135]

Cited: 1 time

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Editorial: The urologist's role in the opioid epidemic.

Kristian D Stensland, Peter Chang, Andrew A Wagner,

Curr Opin Urol (Current opinion in urology)
[2019, 29(4):466-468]

Cited: 0 times

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Comparing histologic evaluation of prostate tissue using nonlinear microscopy and paraffin H&E: a pilot study.

Lucas C Cahill, James G Fujimoto, Michael G Giacomelli, Tadayuki Yoshitake, Yubo Wu, Douglas I Lin, Huihui Ye, Oscar M Carrasco-Zevallos, Andrew A Wagner, Seymour Rosen,

Rapid histological assessment of large areas of prostate tissue is required for many intraoperative consultation scenarios such as margin evaluation. Nonlinear microscopy (NLM) enables imaging of large (whole mount) specimens without freezing or cryotoming. This study demonstrates rapid histological imaging of unsectioned prostate cancer surgical specimens using nonlinear microscopy and compares ... Read more >>

Mod Pathol (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2019, 32(8):1158-1167]

Cited: 9 times

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Selecting Patients with Small Renal Masses for Active Surveillance: A Domain Based Score from a Prospective Cohort Study.

Ayodeji E Sotimehin, Hiten D Patel, Ridwan Alam, Michael A Gorin, Michael H Johnson, Peter Chang, Andrew A Wagner, James M McKiernan, Mohamad E Allaf, Phillip M Pierorazio,

PURPOSE:We sought to identify predictors of active surveillance in a prospective cohort study of patients with a small renal mass demonstrating favorable outcomes. We generated a summary score to discriminate patients selected for active surveillance or primary intervention. MATERIALS AND METHODS:We analyzed the records of 751 patients from 2009 to ... Read more >>

J Urol (The Journal of urology)
[2019, 201(5):886-892]

Cited: 3 times

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Evaluation of Intense Androgen Deprivation Before Prostatectomy: A Randomized Phase II Trial of Enzalutamide and Leuprolide With or Without Abiraterone.

Rana R McKay, Huihui Ye, Wanling Xie, Rosina Lis, Carla Calagua, Zhenwei Zhang, Quoc-Dien Trinh, Steven L Chang, Lauren C Harshman, Ashley E Ross, Kenneth J Pienta, Daniel W Lin, William J Ellis, Bruce Montgomery, Peter Chang, Andrew A Wagner, Glenn J Bubley, Adam S Kibel, Mary-Ellen Taplin,

<h4>Purpose</h4>Patients with locally advanced prostate cancer have an increased risk of cancer recurrence and mortality. In this phase II trial, we evaluate neoadjuvant enzalutamide and leuprolide (EL) with or without abiraterone and prednisone (ELAP) before radical prostatectomy (RP) in men with locally advanced prostate cancer.<h4>Patients and methods</h4>Eligible patients had a ... Read more >>

J Clin Oncol (Journal of clinical oncology : official journal of the American Society of Clinical Oncology)
[2019, 37(11):923-931]

Cited: 16 times

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