Full Text Journal Articles by
Author Andrea R Horvath

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Katy Bell, Jenny Doust, Kevin McGeechan, Andrea R Horvath, Alexandra Barratt, Andrew Hayen, Christopher Semsarian, Les Irwig,

J Hypertens (Journal of hypertension)
[2021, 39(5):1045-1046]

Cited: 0 times

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Guidance for the design and reporting of studies evaluating the clinical performance of tests for present or past SARS-CoV-2 infection.

Jenny A Doust, Katy J L Bell, Mariska M G Leeflang, Jacqueline Dinnes, Sally J Lord, Sue Mallett, Janneke H H M van de Wijgert, Sverre Sandberg, Khosrow Adeli, Jonathan J Deeks, Patrick M Bossuyt, Andrea R Horvath,

BMJ (BMJ (Clinical research ed.))
[2021, 372:n568]

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How to use imperfect tests for COVID-19 (SARS-CoV-2) to make clinical decisions.

Katy Jl Bell, Fiona F Stanaway, Les M Irwig, Andrea R Horvath, Armando Teixeira-Pinto, Clement Loy,

Med J Aust (The Medical journal of Australia)
[2021, 214(2):69-73.e1]

Cited: 1 time

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IFCC Interim Guidelines on Biochemical/Hematological Monitoring of COVID-19 Patients.

Simon Thompson, Mary Kathryn Bohn, Nicasio Mancini, Tze Ping Loh, Cheng-Bin Wang, Matthias Grimmler, Kwok-Yung Yuen, Robert Mueller, David Koch, Sunil Sethi, William D Rawlinson, Massimo Clementi, Rajiv Erasmus, Marc Leportier, Gye Cheol Kwon, María Elizabeth Menezes, Maria-Magdalena Patru, Maurizio Gramegna, Krishna Singh, Osama Najjar, Maurizio Ferrari, Giuseppe Lippi, Khosrow Adeli, Andrea R Horvath, ,

Routine biochemical and hematological tests have been reported to be useful in the stratification and prognostication of pediatric and adult patients with diagnosed coronavirus disease (COVID-19), correlating with poor outcomes such as the need for mechanical ventilation or intensive care, progression to multisystem organ failure, and/or death. While these tests ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2020, 58(12):2009-2016]

Cited: 5 times

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Reference intervals for venous blood gas measurement in adults.

Kirsty L Ress, Gus Koerbin, Ling Li, Douglas Chesher, Phillip Bwititi, Andrea R Horvath,

<h4>Objectives</h4>Venous blood gas (VBG) analysis is becoming a popular alternative to arterial blood gas (ABG) analysis due to reduced risk of complications at phlebotomy and ease of draw. In lack of published data, this study aimed to establish reference intervals (RI) for correct interpretation of VBG results.<h4>Methods</h4>One hundred and 51 ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2021, 59(5):947-954]

Cited: 0 times

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IFCC Interim Guidelines on Molecular Testing of SARS-CoV-2 Infection.

Mary Kathryn Bohn, Nicasio Mancini, Tze Ping Loh, Cheng-Bin Wang, Matthias Grimmler, Maurizio Gramegna, Kwok-Yung Yuen, Robert Mueller, David Koch, Sunil Sethi, William D Rawlinson, Massimo Clementi, Rajiv Erasmus, Marc Leportier, Gye Cheol Kwon, María Elizabeth Menezes, Maria-Magdalena Patru, Krishna Singh, Maurizio Ferrari, Osama Najjar, Andrea R Horvath, Khosrow Adeli, Giuseppe Lippi,

The diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection globally has relied extensively on molecular testing, contributing vitally to case identification, isolation, contact tracing, and rationalization of infection control measures during the coronavirus disease 2019 (COVID-19) pandemic. Clinical laboratories have thus needed to verify newly developed molecular tests ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2020, 58(12):1993-2000]

Cited: 3 times

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Editorial and Executive Summary: IFCC Interim Guidelines on Clinical Laboratory testing during the COVID-19 Pandemic.

Giuseppe Lippi, Andrea R Horvath, Khosrow Adeli,

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2020, 58(12):1965-1969]

Cited: 0 times

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IFCC Interim Guidelines on Serological Testing of Antibodies against SARS-CoV-2.

Mary Kathryn Bohn, Tze Ping Loh, Cheng-Bin Wang, Robert Mueller, David Koch, Sunil Sethi, William D Rawlinson, Massimo Clementi, Rajiv Erasmus, Marc Leportier, Matthias Grimmler, K Y Yuen, Nicasio Mancini, Gye Cheol Kwon, María Elizabeth Menezes, Maria-Magdalena Patru, Maurizio Gramegna, Krishna Singh, Osama Najjar, Maurizio Ferrari, Andrea R Horvath, Giuseppe Lippi, Khosrow Adeli, ,

Serological testing for the detection of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is emerging as an important component of the clinical management of patients with coronavirus disease 2019 (COVID-19) as well as the epidemiological assessment of SARS-CoV-2 exposure worldwide. In addition to molecular testing for the detection ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2020, 58(12):2001-2008]

Cited: 7 times

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Biosafety measures for preventing infection from COVID-19 in clinical laboratories: IFCC Taskforce Recommendations.

Giuseppe Lippi, Khosrow Adeli, Maurizio Ferrari, Andrea R Horvath, David Koch, Sunil Sethi, Cheng-Bin Wang,

Coronavirus disease 2019 (COVID-19) is the third coronavirus outbreak that has emerged in the past 20 years, after severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). One important aspect, highlighted by many global health organizations, is that this novel coronavirus outbreak may be especially hazardous to healthcare ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2020, 58(7):1053-1062]

Cited: 6 times

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Under-detection of acute kidney injury in hospitalised patients: a retrospective, multi-site, longitudinal study.

Craig A Campbell, Ling Li, Sradha Kotwal, Andrew Georgiou, Andrea R Horvath, Johanna Westbrook, Zoltan Endre,

BACKGROUND:Acute kidney injury (AKI) is a rapid deterioration of renal function, often caused by a variety of co-existing morbidities complicating its recognition and treatment, leading to short- and long-term adverse clinical outcomes. There are limited data on the incidence of AKI in Australia using the Kidney Disease Improving Global Outcomes ... Read more >>

Intern Med J (Internal medicine journal)
[2020, 50(3):307-314]

Cited: 2 times

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Setting clinical performance specifications to develop and evaluate biomarkers for clinical use.

Sarah J Lord, Andrew St John, Patrick Mm Bossuyt, Sverre Sandberg, Phillip J Monaghan, Maurice O'Kane, Christa M Cobbaert, Ralf Röddiger, Lieselotte Lennartz, Cecilia Gelfi, Andrea R Horvath, ,

Ann Clin Biochem (Annals of clinical biochemistry)
[2019, 56(5):527-535]

Cited: 3 times

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An evidence- and risk-based approach to a harmonized laboratory alert list in Australia and New Zealand.

Craig A Campbell, Que Lam, Andrea R Horvath,

Individual laboratories are required to compose an alert list for identifying critical and significant risk results. The high-risk result working party of the Royal College of Pathologists of Australasia (RCPA) and the Australasian Association of Clinical Biochemists (AACB) has developed a risk-based approach for a harmonized alert list for laboratories ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2018, 57(1):89-94]

Cited: 1 time

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Patient groups, clinicians and healthcare professionals agree - all test results need to be seen, understood and followed up.

Maria R Dahm, Andrew Georgiou, Robert Herkes, Anthony Brown, Julie Li, Robert Lindeman, Andrea R Horvath, Graham Jones, Michael Legg, Ling Li, David Greenfield, Johanna I Westbrook,

Background Diagnostic testing provides integral information for the prevention, diagnosis, treatment and management of disease. Inadequate test result reporting and follow-up is a major risk to patient safety. Factors contributing to failure to follow-up test results include unclear delineation of responsibility about who is meant to act on a test ... Read more >>

Diagnosis (Berl) (Diagnosis (Berlin, Germany))
[2018, 5(4):215-222]

Cited: 1 time

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Practical guide for identifying unmet clinical needs for biomarkers.

Phillip J Monaghan, Sarah Robinson, Daniel Rajdl, Patrick M M Bossuyt, Sverre Sandberg, Andrew St John, Maurice O'Kane, Lieselotte Lennartz, Ralf Röddiger, Sarah J Lord, Christa M Cobbaert, Andrea R Horvath,

The development and evaluation of novel biomarkers and testing strategies requires a close examination of existing clinical pathways, including mapping of current pathways and identifying areas of unmet need. This approach enables early recognition of analytical and clinical performance criteria to guide evaluation studies, in a cyclical and iterative manner, ... Read more >>

EJIFCC (EJIFCC)
[2018, 29(2):129-137]

Cited: 7 times

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Delivering safe and effective test-result communication, management and follow-up: a mixed-methods study protocol.

Maria R Dahm, Andrew Georgiou, Johanna I Westbrook, David Greenfield, Andrea R Horvath, Denis Wakefield, Ling Li, Ken Hillman, Patrick Bolton, Anthony Brown, Graham Jones, Robert Herkes, Robert Lindeman, Michael Legg, Meredith Makeham, Daniel Moses, Dauda Badmus, Craig Campbell, Rae-Anne Hardie, Julie Li, Euan McCaughey, Gorkem Sezgin, Judith Thomas, Nasir Wabe,

INTRODUCTION:The failure to follow-up pathology and medical imaging test results poses patient-safety risks which threaten the effectiveness, quality and safety of patient care. The objective of this project is to: (1) improve the effectiveness and safety of test-result management through the establishment of clear governance processes of communication, responsibility and ... Read more >>

BMJ Open (BMJ open)
[2018, 8(2):e020235]

Cited: 7 times

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Guidance for Modifying the Definition of Diseases: A Checklist.

Jenny Doust, Per O Vandvik, Amir Qaseem, Reem A Mustafa, Andrea R Horvath, Allen Frances, Lubna Al-Ansary, Patrick Bossuyt, Robyn L Ward, Ina Kopp, Laragh Gollogly, Holger Schunemann, Paul Glasziou, ,

<h4>Importance</h4>No guidelines exist currently for guideline panels and others considering changes to disease definitions. Panels frequently widen disease definitions, increasing the proportion of the population labeled as unwell and potentially causing harm to patients. We set out to develop a checklist of issues, with guidance, for panels to consider prior ... Read more >>

JAMA Intern Med (JAMA internal medicine)
[2017, 177(7):1020-1025]

Cited: 26 times

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Sex steroid hormone stability in serum tubes with and without separator gels.

Sophie Hepburn, Michael J P Wright, Conchita Boyder, Renee C Sahertian, Ben Lu, Rui Zhang, Chris P White, Andrea R Horvath,

<h4>Background</h4>A pilot study showing a decrease in androstenedione concentration in serum collected into gel-containing serum tubes (STs) triggered an investigation of the effect of serum collection tube on steroid hormone stability.<h4>Methods</h4>In the main study, two tube types were examined: BD Vacutainer® SST™II Advance and BD Vacutainer® Serum Tube. Forty-seven serum ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2016, 54(9):1451-1459]

Cited: 3 times

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Biomarker development targeting unmet clinical needs.

Phillip J Monaghan, Sarah J Lord, Andrew St John, Sverre Sandberg, Christa M Cobbaert, Lieselotte Lennartz, Wilma D J Verhagen-Kamerbeek, Christoph Ebert, Patrick M M Bossuyt, Andrea R Horvath, ,

<h4>Background</h4>The introduction of new biomarkers can lead to inappropriate utilization of tests if they do not fill in existing gaps in clinical care. We aimed to define a strategy and checklist for identifying unmet needs for biomarkers.<h4>Methods</h4>A multidisciplinary working group used a 4-step process: 1/ scoping literature review; 2/ face-to-face ... Read more >>

Clin Chim Acta (Clinica chimica acta; international journal of clinical chemistry)
[2016, 460:211-219]

Cited: 10 times

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What Alert Thresholds Should Be Used to Identify Critical Risk Results: A Systematic Review of the Evidence.

Craig A Campbell, Andrew Georgiou, Johanna I Westbrook, Andrea R Horvath,

<h4>Background</h4>Pathology laboratories are required to immediately report results which indicate a patient is at critical risk, but there is little consensus about what values are deemed critical. The aim of this review was to systematically review the literature on alert thresholds for common chemistry and hematology tests in adults and ... Read more >>

Clin Chem (Clinical chemistry)
[2016, 62(11):1445-1457]

Cited: 7 times

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Biological variation of high sensitivity cardiac troponin-T in stable dialysis patients: implications for clinical practice.

Magid A Fahim, Andrew D Hayen, Andrea R Horvath, Goce Dimeski, Amanda Coburn, Ken-Soon Tan, David W Johnson, Jonathan C Craig, Scott B Campbell, Carmel M Hawley,

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2016, 54(5):e149-50]

Cited: 0 times

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Are Guidelines Guiding us on How to Utilize Laboratory Tests?

Andrea R Horvath,

Increasing patient risks and costs associated with the delivery of health care services have been related to inappropriate and uncontrolled use of biomarkers which make evidence-based guideline recommendations for best practice increasingly important. The translation of basic scientific discoveries into clinically meaningful studies and then to evidence-based clinical practice guidelines ... Read more >>

EJIFCC (EJIFCC)
[2015, 26(3):146-157]

Cited: 0 times

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Multiple reaction monitoring with multistage fragmentation (MRM3) detection enhances selectivity for LC-MS/MS analysis of plasma free metanephrines.

Michael J Wright, Rebecca L Thomas, Phoebe E Stanford, Andrea R Horvath,

<h4>Background</h4>LC-MS/MS with multiple reaction monitoring (MRM) is a powerful tool for quantifying target analytes in complex matrices. However, the technique lacks selectivity when plasma free metanephrines are measured. We propose the use of multistage fragmentation (MRM(3)) to improve the analytical selectivity of plasma free metanephrine measurement.<h4>Methods</h4>Metanephrines were extracted from plasma ... Read more >>

Clin Chem (Clinical chemistry)
[2015, 61(3):505-513]

Cited: 3 times

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Biological variation of high sensitivity cardiac troponin-T in stable dialysis patients: implications for clinical practice.

Magid A Fahim, Andrew D Hayen, Andrea R Horvath, Goce Dimeski, Amanda Coburn, Ken-Soon Tan, David W Johnson, Jonathan C Craig, Scott B Campbell, Carmel M Hawley,

<h4>Background</h4>Changes in high sensitivity cardiac troponin-T (hs-cTnT) concentrations may reflect either acute myocardial injury or biological variation. Distinguishing between these entities is essential to accurate diagnosis, however, the biological variation of hs-cTnT in dialysis population is currently unknown. We sought to estimate the within- and between-person coefficients of variation of ... Read more >>

Clin Chem Lab Med (Clinical chemistry and laboratory medicine)
[2015, 53(5):715-722]

Cited: 7 times

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Increased rates of infantile hypercalcaemia following guidelines for antenatal vitamin D3 supplementation

Lisa A Amato, Shihab Hameed, Kris A Neville, Wei Shern Quek, Andrea R Horvath, Chris P White, Charles F Verge, Helen J Woodhead, Jan L Walker,

Int J Pediatr Endocrinol (International journal of pediatric endocrinology)
[2015, 2015(Suppl 1):O42-O42]

Cited: 0 times

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N-terminal pro-B-type natriuretic peptide variability in stable dialysis patients.

Magid A Fahim, Andrew Hayen, Andrea R Horvath, Goce Dimeski, Amanda Coburn, David W Johnson, Carmel M Hawley, Scott B Campbell, Jonathan C Craig,

<h4>Background and objectives</h4>Monitoring N-terminal pro-B-type natriuretic peptide (NT-proBNP) may be useful for assessing cardiovascular risk in dialysis patients. However, its biologic variation is unknown, hindering the accurate interpretation of serial concentrations. The aims of this prospective cohort study were to estimate the within- and between-person coefficients of variation of NT-proBNP ... Read more >>

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2015, 10(4):620-629]

Cited: 14 times

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