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Prevalence and Clinical Implications of COVID-19 Myocarditis

Cristina Chimenti, Michele Magnocavallo, Federico Ballatore, Federico Bernardini, Maria Alfarano, Domenico Giovanni Della Rocca, Paolo Severino, Carlo Lavalle, Fedele Francesco, Andrea Frustaci,

Synopsis The clinical manifestations of COVID-19 are widely variable and may involve several districts. Although the clinical course is mostly characterized by respiratory involvement, up to 30% of hospitalized patients have evidence of myocardial injury due to acute coronary syndrome, cardiac arrhythmias, myocarditis, and cardiogenic shock. In particular, myocarditis is ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2021, :]

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Myocardial Aldosterone Receptor and Aquaporin 1 Up-Regulation Is Associated with Cardiomyocyte Remodeling in Human Heart Failure

Andrea Frustaci, Claudio Letizia, Cristina Chimenti, Romina Verardo, Maria Alfarano, Rossella Scialla, Giulia Bagnato, Fabio Miraldi, Luigi Sansone, Matteo Antonio Russo,

Background: Abnormal aldosterone signaling is a recognized source of cardiovascular damage. Its influence on cardiomyocyte structure, function, and hormonal receptors when associated with heart failure is still unreported. Methods: Twenty-six consecutive patients with heart failure (LVEF < 40%) and normal coronaries and valves underwent left ventricular endomyocardial biopsy (EMB) for ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(21):]

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Myocardial Aldosterone Receptor and Aquaporin 1 Up-Regulation Is Associated with Cardiomyocyte Remodeling in Human Heart Failure.

Andrea Frustaci, Claudio Letizia, Cristina Chimenti, Romina Verardo, Maria Alfarano, Rossella Scialla, Giulia Bagnato, Fabio Miraldi, Luigi Sansone, Matteo Antonio Russo,

<h4>Background</h4>Abnormal aldosterone signaling is a recognized source of cardiovascular damage. Its influence on cardiomyocyte structure, function, and hormonal receptors when associated with heart failure is still unreported.<h4>Methods</h4>Twenty-six consecutive patients with heart failure (LVEF < 40%) and normal coronaries and valves underwent left ventricular endomyocardial biopsy (EMB) for evaluation of myocardial ... Read more >>

J Clin Med (Journal of clinical medicine)
[2021, 10(21):]

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Pemphigus-associated cardiomyopathy: report of autoimmune myocarditis and review of literature.

Andrea Frustaci, Marco Francone, Romina Verardo, Rossella Scialla, Giulia Bagnato, Maria Alfarano, Cristina Chimenti, Emanuela Frustaci, Luigi Sansone, Matteo Russo,

Pemphigus is a rare disease characterized by bullous lesions of the skin and mucous membranes. The aetiology is autoimmune and related to the formation of IgG autoantibodies against desmogleins, which are structural proteins of desmosomes that ensure the stability of contacts between cells. Cardiac involvement in patients with pemphigus is ... Read more >>

ESC Heart Fail (ESC heart failure)
[2021, 8(5):3690-3695]

Cited: 1 time

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Virus-Negative Necrotizing Coronary Vasculitis with Aneurysm Formation in Human SARS-CoV-2 Infection.

Andrea Frustaci, Marco Francone, Romina Verardo, Maria Rosaria Capobianchi, Cristina Chimenti,

We report a case of myopericarditis associated to SARS-CoV-2 infection with necrotizing coronary vasculitis of intramural vessels, giving rise to biventricular apical microaneurysms and to electrical instability. Negativity of myocardial polymerase chain reaction for the most common cardiotropic viruses and for SARS-CoV-2 suggested an immune-mediated myocardial and pericardial inflammatory disease. ... Read more >>

Infect Dis Rep (Infectious disease reports)
[2021, 13(3):597-601]

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Prophylactic heparin and risk of orotracheal intubation or death in patients with mild or moderate COVID-19 pneumonia.

Alessandra Vergori, Patrizia Lorenzini, Alessandro Cozzi-Lepri, Davide Roberto Donno, Gina Gualano, Emanuele Nicastri, Fabio Iacomi, Luisa Marchioni, Paolo Campioni, Vincenzo Schininà, Stefania Cicalini, Chiara Agrati, Maria Rosaria Capobianchi, Enrico Girardi, Giuseppe Ippolito, Francesco Vaia, Nicola Petrosillo, Andrea Antinori, Fabrizio Taglietti, ,

Prophylactic low molecular weight heparin (pLMWH) is currently recommended in COVID-19 to reduce the risk of coagulopathy. The aim of this study was to evaluate whether the antinflammatory effects of pLMWH could translate in lower rate of clinical progression in patients with COVID-19 pneumonia. Patients admitted to a COVID-hospital in ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):11334]

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False-positive bone scintigraphy denoting transthyretin amyloid in elderly hypertrophic cardiomyopathy.

Cristina Chimenti, Maria Alfarano, Viviana Maestrini, Nicola Galea, Giuseppe De Vincentis, Romina Verardo, Francesco Fedele, Andrea Frustaci,

A positive nuclear scintigraphy with hydroxy bisphosphonate bone tracer (99mTc-HPD) is believed to have high sensitivity (>99%) and specificity (91%) for the diagnosis of transthyretin amyloid cardiomyopathy. We report the case of an 85-year-old man with increased thickness of ventricular walls and a positive bone scintigraphy, who was unexpectedly found ... Read more >>

ESC Heart Fail (ESC heart failure)
[2021, 8(4):3387-3391]

Cited: 1 time

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Hypertrophy of unaffected cardiomyocytes correlates with severity of cardiomyopathy in female patients with Fabry disease.

Cristina Chimenti, Romina Verardo, Andrea Frustaci,

<h4>Aim</h4>To investigate the contribution of unaffected cardiomyocytes in Fabry disease cardiomyopathy.<h4>Findings</h4>Left ventricular (LV) endomyocardial biopsies from twenty-four females (mean age 53 ± 11 ys) with Fabry disease cardiomyopathy were studied. Diagnosis of FD was based on the presence of pathogenic GLA mutation, Patients were divided in four groups according with LV maximal ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2021, 16(1):169]

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Myocarditis-associated necrotizing coronary vasculitis: incidence, cause, and outcome.

Andrea Frustaci, Maria Alfarano, Romina Verardo, Chiara Agrati, Rita Casetti, Fabio Miraldi, Nicola Galea, Claudio Letizia, Cristina Chimenti,

<h4>Aims</h4>Necrotizing coronary vasculitis (NCV) is a rare entity usually associated to myocarditis which incidence, cause, and response to therapy is unreported.<h4>Methods and results</h4>Among 1916 patients with biopsy-proven myocarditis, 30 had NCV. Endomyocardial samples were retrospectively investigated with immunohistochemistry for toll-like receptor 4 (TLR4) and real-time polymerase chain reaction (PCR) for ... Read more >>

Eur Heart J (European heart journal)
[2021, 42(16):1609-1617]

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Risk and predictive factors of prolonged viral RNA shedding in upper respiratory specimens in a large cohort of COVID-19 patients admitted to an Italian reference hospital.

Annalisa Mondi, Patrizia Lorenzini, Concetta Castilletti, Roberta Gagliardini, Eleonora Lalle, Angela Corpolongo, Maria Beatrice Valli, Fabrizio Taglietti, Stefania Cicalini, Laura Loiacono, Francesco Di Gennaro, Gianpiero D'Offizi, Fabrizio Palmieri, Emanuele Nicastri, Chiara Agrati, Nicola Petrosillo, Giuseppe Ippolito, Francesco Vaia, Enrico Girardi, Maria Rosaria Capobianchi, Andrea Antinori, Sara Zito, Maria Alessandra Abbonizio, Amina Abdeddaim, Elisabetta Agostini, Chiara Agrati, Fabrizio Albarello, Gioia Amadei, Alessandra Amendola, Andrea Antinori, Maria Assunta Antonica, Mario Antonini, Tommaso Ascoli Bartoli, Francesco Baldini, Raffaella Barbaro, Barbara Bartolini, Rita Bellagamba, Martina Benigni, Nazario Bevilacqua, Gianluigi Biava, Michele Bibas, Licia Bordi, Veronica Bordoni, Evangelo Boumis, Marta Branca, Rosanna Buonomo, Donatella Busso, Marta Camici, Paolo Campioni, Flaminia Canichella, Maria Rosaria Capobianchi, Alessandro Capone, Cinzia Caporale, Emanuela Caraffa, Ilaria Caravella, Fabrizio Carletti, Concetta Castilletti, Adriana Cataldo, Stefano Cerilli, Carlotta Cerva, Roberta Chiappini, Pierangelo Chinello, Maria Assunta Cianfarani, Carmine Ciaralli, Claudia Cimaglia, Nicola Cinicola, Veronica Ciotti, Stefania Cicalini, Francesca Colavita, Angela Corpolongo, Massimo Cristofaro, Salvatore Curiale, Alessandra D'Abramo, Cristina Dantimi, Alessia De Angelis, Giada De Angelis, Maria Grazia De Palo, Federico De Zottis, Virginia Di Bari, Rachele Di Lorenzo, Federica Di Stefano, Gianpiero D'Offizi, Davide Donno, Francesca Evangelista, Francesca Faraglia, Anna Farina, Federica Ferraro, Lorena Fiorentini, Andrea Frustaci, Matteo Fusetti, Vincenzo Galati, Roberta Gagliardini, Paola Gallì, Gabriele Garotto, Ilaria Gaviano, Saba Gebremeskel Tekle, Maria Letizia Giancola, Filippo Giansante, Emanuela Giombini, Guido Granata, Maria Cristina Greci, Elisabetta Grilli, Susanna Grisetti, Gina Gualano, Fabio Iacomi, Marta Iaconi, Giuseppina Iannicelli, Carlo Inversi, Giuseppe Ippolito, Eleonora Lalle, Maria Elena Lamanna, Simone Lanini, Daniele Lapa, Luciana Lepore, Raffaella Libertone, Raffaella Lionetti, Giuseppina Liuzzi, Laura Loiacono, Andrea Lucia, Franco Lufrani, Manuela Macchione, Gaetano Maffongelli, Alessandra Marani, Luisa Marchioni, Andrea Mariano, Maria Cristina Marini, Micaela Maritti, Annelisa Mastrobattista, Ilaria Mastrorosa, Giulia Matusali, Valentina Mazzotta, Paola Mencarini, Silvia Meschi, Francesco Messina, Sibiana Micarelli, Giulia Mogavero, Annalisa Mondi, Marzia Montalbano, Chiara Montaldo, Silvia Mosti, Silvia Murachelli, Maria Musso, Michela Nardi, Assunta Navarra, Emanuele Nicastri, Martina Nocioni, Pasquale Noto, Roberto Noto, Alessandra Oliva, Ilaria Onnis, Sandrine Ottou, Claudia Palazzolo, Emanuele Pallini, Fabrizio Palmieri, Giulio Palombi, Carlo Pareo, Virgilio Passeri, Federico Pelliccioni, Giovanna Penna, Antonella Petrecchia, Ada Petrone, Nicola Petrosillo, Elisa Pianura, Carmela Pinnetti, Maria Pisciotta, Pierluca Piselli, Silvia Pittalis, Agostina Pontarelli, Costanza Proietti, Vincenzo Puro, Paolo Migliorisi Ramazzini, Alessia Rianda, Gabriele Rinonapoli, Silvia Rosati, Dorotea Rubino, Martina Rueca, Alberto Ruggeri, Alessandra Sacchi, Alessandro Sampaolesi, Francesco Sanasi, Carmen Santagata, Alessandra Scarabello, Silvana Scarcia, Vincenzo Schininà, Paola Scognamiglio, Laura Scorzolini, Giulia Stazi, Giacomo Strano, Fabrizio Taglietti, Chiara Taibi, Giorgia Taloni, Tetaj Nardi, Roberto Tonnarini, Simone Topino, Martina Tozzi, Francesco Vaia, Francesco Vairo, Maria Beatrice Valli, Alessandra Vergori, Laura Vincenzi, Ubaldo Visco-Comandini, Serena Vita, Pietro Vittozzi, Mauro Zaccarelli, Antonella Zanetti, Sara Zito, ,

<h4>Background</h4>Limited data are available about the predictors and outcomes associated with prolonged SARS-CoV-2 RNA shedding (VS).<h4>Methods</h4>A retrospective study including COVID-19 patients admitted to an Italian hospital between March 1 and July 1, 2020. Predictors of viral clearance (VC) and prolonged VS from the upper respiratory tract were assessed by Poisson ... Read more >>

Int J Infect Dis (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2021, 105:532-539]

Cited: 3 times

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Down Syndrome patients with COVID-19 pneumonia: A high-risk category for unfavourable outcome.

Serena Vita, Virginia Di Bari, Angela Corpolongo, Delia Goletti, Joaquin Espinosa, Sebastiano Petracca, Fabrizio Palmieri, Emanuele Nicastri, ,

We report two cases of Corona Virus Disease-19 (COVID-19) in patients with Down Syndrome (DS) and describe the identification, diagnosis, clinical course and management of the infection. Down Syndrome, which is caused by trisomy 21, is characterized by immune dysregulation, anatomical differences in the upper respiratory tract and higher rate ... Read more >>

Int J Infect Dis (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2021, 103:607-610]

Cited: 2 times

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[ANMCO/SIC Consensus document on the management of myocarditis].

Manlio Cipriani, Marco Merlo, Domenico Gabrielli, Enrico Ammirati, Camillo Autore, Cristina Basso, Alida Caforio, Pasquale Caldarola, Paolo Camici, Andrea Di Lenarda, Andrea Frustaci, Massimo Imazio, Fabrizio Oliva, Patrizia Pedrotti, Martina Perazzolo Marra, Claudio Rapezzi, Stefano Urbinati, Massimo Zecchin, Pasquale Perrone Filardi, Furio Colivicchi, Ciro Indolfi, Maria Frigerio, Gianfranco Sinagra,

Myocarditis is an inflammatory heart disease that can occur acutely, as in acute myocarditis, or persistently, as in chronic myocarditis or chronic inflammatory cardiomyopathy. Different agents can induce myocarditis, with viruses being the most common triggers. Generally, acute myocarditis affects relatively young people and men more than women. Myocarditis has ... Read more >>

G Ital Cardiol (Rome) (Giornale italiano di cardiologia (2006))
[2020, 21(12):969-989]

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Use of the new Lake Louise Criteria improves CMR detection of atypical forms of acute myocarditis.

Giulia Cundari, Nicola Galea, Gianluca De Rubeis, Andrea Frustaci, Francesco Cilia, Giuseppe Mancuso, Livia Marchitelli, Federica Catapano, Iacopo Carbone, Carlo Catalano, Marco Francone,

The purpose of our study was to compare diagnostic performance of old and new Lake Louise Criteria (oLLC and nLLC) among different clinical presentations: infarct-like (IL), cardiomyopathic (CM) and arrhythmic (AR). 102 patients with clinical suspicion of acute myocarditis underwent cardiac magnetic resonance (CMR) on a 1.5 T scanner. Protocol included cine-SSFP, ... Read more >>

Int J Cardiovasc Imaging (The international journal of cardiovascular imaging)
[2021, 37(4):1395-1404]

Cited: 2 times

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Inflammation of Conduction Tissue in Patients with Arrhythmic Phenotype of Myocarditis.

Andrea Frustaci, Romina Verardo, Maria Alfarano, Cristina Chimenti,

<h4>Background</h4>Myocarditis can manifest with lone ventricular tachyarrhythmias (LVT). Elective inflammation of conduction tissue (CT) is supposed but unproved.<h4>Methods</h4>Forty-two of 420 patients with biopsy proven myocarditis presented with LVT. Twelve of them included CT sections in endomyocardial biopsies. Real-time polymerase chain reaction (PCR) for viral genomes, immunohistochemistry for viral antigens and ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(11):]

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Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: findings from the opinion-based PREDICT-FD modified Delphi consensus initiative.

Derralynn A Hughes, Patricio Aguiar, Patrick B Deegan, Fatih Ezgu, Andrea Frustaci, Olivier Lidove, Aleš Linhart, Jean-Claude Lubanda, James C Moon, Kathleen Nicholls, Dau-Ming Niu, Albina Nowak, Uma Ramaswami, Ricardo Reisin, Paula Rozenfeld, Raphael Schiffmann, Einar Svarstad, Mark Thomas, Roser Torra, Bojan Vujkovac, David G Warnock, Michael L West, Jack Johnson, Mark J Rolfe, Sandro Feriozzi,

<h4>Objectives</h4>The PRoposing Early Disease Indicators for Clinical Tracking in Fabry Disease (PREDICT-FD) initiative aimed to reach consensus among a panel of global experts on early indicators of disease progression that may justify FD-specific treatment initiation.<h4>Design and setting</h4>Anonymous feedback from panellists via online questionnaires was analysed using a modified Delphi consensus ... Read more >>

BMJ Open (BMJ open)
[2020, 10(10):e035182]

Cited: 3 times

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Myocarditis and intramural coronary vasculitis in polyarteritis nodosa: an unusual treatable form of heart failure.

Cristina Chimenti, Maria Alfarano, Federica Toto, Francesca Fanisio, Romina Verardo, Nicola Galea, Luciano Agati, Andrea Frustaci,

We describe an uncommon cardiac presentation of polyarteritis nodosa. A 68-year-old woman, with a history of fatigue, weight loss, and myalgia of the lower extremities, was admitted for congestive heart failure. Coronary arteries were normal. Endomyocardial biopsy showed active lymphocytic myocarditis with associated intramural small vessels necrotizing vasculitis. The overexpression ... Read more >>

ESC Heart Fail (ESC heart failure)
[2020, :]

Cited: 0 times

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Pharmacokinetics of remdesivir and GS-441524 in two critically ill patients who recovered from COVID-19.

Massimo Tempestilli, Priscilla Caputi, Valeria Avataneo, Stefania Notari, Olindo Forini, Laura Scorzolini, Luisa Marchioni, Tommaso Ascoli Bartoli, Concetta Castilletti, Eleonora Lalle, Maria R Capobianchi, Emanuele Nicastri, Antonio D'Avolio, Giuseppe Ippolito, Chiara Agrati, ,

<h4>Background</h4>Remdesivir is a prodrug of the nucleoside analogue GS-441524 and is under evaluation for treatment of SARS-CoV-2-infected patients.<h4>Objectives</h4>To evaluate the pharmacokinetics of remdesivir and GS-441524 in plasma, bronchoalveolar aspirate (BAS) and CSF in two critically ill COVID-19 patients.<h4>Methods</h4>Remdesivir was administered at 200 mg loading dose on the first day followed by ... Read more >>

J Antimicrob Chemother (The Journal of antimicrobial chemotherapy)
[2020, 75(10):2977-2980]

Cited: 32 times

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Virological Characterization of the First 2 COVID-19 Patients Diagnosed in Italy: Phylogenetic Analysis, Virus Shedding Profile From Different Body Sites, and Antibody Response Kinetics.

Francesca Colavita, Daniele Lapa, Fabrizio Carletti, Eleonora Lalle, Francesco Messina, Martina Rueca, Giulia Matusali, Silvia Meschi, Licia Bordi, Patrizia Marsella, Emanuele Nicastri, Luisa Marchioni, Andrea Mariano, Laura Scorzolini, Tommaso Ascoli Bartoli, Antonino Di Caro, Giuseppe Ippolito, Maria Rosaria Capobianchi, Concetta Castilletti, ,

<h4>Background</h4>The pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains unclear. We report the detection of viral RNA from different anatomical districts and the antibody profile in the first 2 COVID-19 cases diagnosed in Italy.<h4>Methods</h4>We tested for SARS-CoV-2 RNA clinical samples, either respiratory and nonrespiratory (ie, saliva, serum, ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(10):ofaa403]

Cited: 5 times

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Undiagnosed Fabry disease: the importance of screening for Fabry disease before transcutaneous patent foramen ovale closure in a young patient with cryptogenic stroke.

Cristina Chimenti, Maria Alfarano, Nicola Galea, Romina Verardo, Claudia Grande, Andrea Frustaci,

J Cardiovasc Med (Hagerstown) (Journal of cardiovascular medicine (Hagerstown, Md.))
[2020, 21(9):711-713]

Cited: 0 times

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ESC EORP Cardiomyopathy Registry: real-life practice of genetic counselling and testing in adult cardiomyopathy patients.

Tiina Heliö, Perry Elliott, Juha W Koskenvuo, Juan R Gimeno, Luigi Tavazzi, Michal Tendera, Juan Pablo Kaski, Nicolas Mansencal, Zofia Bilińska, Gerry Carr-White, Thibaud Damy, Andrea Frustaci, Ingrid Kindermann, Tomas Ripoll-Vera, Jelena Čelutkienė, Anna Axelsson, Massimiliano Lorenzini, Aly Saad, Aldo P Maggioni, Cécile Laroche, Alida L P Caforio, Philippe Charron, ,

<h4>Aims</h4>Cardiomyopathies comprise a heterogeneous group of diseases, often of genetic origin. We assessed the current practice of genetic counselling and testing in the prospective European Society of Cardiology EURObservational Research Programme Cardiomyopathy Registry.<h4>Methods and results</h4>A total of 3208 adult patients from 69 centres in 18 countries were enrolled. Genetic counselling ... Read more >>

ESC Heart Fail (ESC heart failure)
[2020, 7(5):3013-3021]

Cited: 3 times

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Kappa-light Chain Amyloid Overlapping Hypertrophic Cardiomyopathy With Myocardial Noncompaction.

Andrea Frustaci, Nicola Galea, Romina Verardo, Marco Francone, Maria Alfarano, Matteo Antonio Russo, Cristina Chimenti,

Circ Cardiovasc Imaging (Circulation. Cardiovascular imaging)
[2020, 13(7):e010379]

Cited: 0 times

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Cardiomyopathies and Adrenal Diseases.

Luigi Petramala, Antonio Concistrè, Federica Olmati, Vincenza Saracino, Cristina Chimenti, Andrea Frustaci, Matteo A Russo, Claudio Letizia,

Cardiomyopathies are myocardial disorders in which heart muscle is structurally and/or functionally abnormal. Previously, structural cardiomyocyte disorders due to adrenal diseases, such as hyperaldosteronism, hypercortisolism, and hypercatecholaminism, were misunderstood, and endomyocardial biopsy (EMB) was not performed because was considered dangerous and too invasive. Recent data confirm that, if performed in ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(14):]

Cited: 2 times

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Fabry cardiomyopathy: Gb3-induced auto-reactive panmyocarditis requiring heart transplantation.

Andrea Frustaci, Maurizio Scarpa, Rosalia Maria da Riol, Chiara Agrati, Nicoletta Finato, Romina Verardo, Claudia Grande, Cristina Chimenti, Concetta Di Nora, Matteo Antonio Russo, Ugolini Livi,

Resistance to enzyme replacement therapy (ERT) is a major therapeutic challenge in Fabry disease (FD). Recent reports attribute to immune-mediated inflammation a main role in promoting disease progression and resistance to ERT. Aim of the study is to report a Gb3-induced auto-reactive panmyocarditis causing inefficacy of ERT and severe electrical ... Read more >>

ESC Heart Fail (ESC heart failure)
[2020, 7(3):1331-1337]

Cited: 4 times

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Infarct-like myocarditis with coronary vasculitis and aneurysm formation caused by Epstein-Barr virus infection

Cristina Chimenti, Romina Verardo, Claudia Grande, Marco Francone, Andrea Frustaci,

Myocardial infection by Epstein-Barr virus (EBV) may manifest with inflammatory cardiomyopathy, coronary syndrome X, and rarely with infarct-like myocarditis. The aim of the report is to describe a case of myocardial EBV infection causing acute myocarditis with heart failure, necrotizing coronary vasculitis, and multiple left ventricular (LV) aneurysms. A 67-year-old ... Read more >>

ESC Heart Fail (ESC heart failure)
[2020, 7(3):938-941]

Cited: 2 times

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2019-novel Coronavirus severe adult respiratory distress syndrome in two cases in Italy: An uncommon radiological presentation.

Fabrizio Albarello, Elisa Pianura, Federica Di Stefano, Massimo Cristofaro, Ada Petrone, Luisa Marchioni, Claudia Palazzolo, Vincenzo Schininà, Emanuele Nicastri, Nicola Petrosillo, Paolo Campioni, Petersen Eskild, Alimuddin Zumla, Giuseppe Ippolito, ,

<h4>Introduction</h4>Several recent case reports have described common early chest imaging findings of lung pathology caused by 2019 novel Coronavirus (SARS-COV2) which appear to be similar to those seen previously in SARS-CoV and MERS-CoV infected patients.<h4>Objective</h4>We present some remarkable imaging findings of the first two patients identified in Italy with COVID-19 ... Read more >>

Int J Infect Dis (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2020, 93:192-197]

Cited: 65 times

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