Full Text Journal Articles by
Author Amit Mishra

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MyrliMax® and Low Back Pain: A Multicentric, Observational, Post-Marketing Surveillance Study in Indian Patients Suffering from Chronic Low Back Pain of Various Pain Intensity.

Varun Sureja, Dharmeshkumar Kheni, Divyanshu Prajapati, Mayank Rajawat, Ajit Magar, Asha Krishnaraj, Ashish Sirsikar, A Arun Prasath, Amit Mishra, Anil Singh Rajput, Balasubramanian Vijayakrishnan, Chetan Puram, D Manoj Kumar, Diwakar Agarwal, Girish Shiragambhi, Jitendra Patil, K Ravichandran, Kailash Nath Jain, M Thayaga Raju, Rajesh Arora, S Nawazish, Sachin Chhabra, Lakshminarayan Shyam, Sudarshan Is, Vinay Aggarwal,

<b>Background:</b> Chronic low back pain (LBP) is the most common musculoskeletal condition affecting a person's quality of life. Over the past decades, a lot of work was done in an attempt to reduce the negative impact of LBP, and help patients recover and maintain a better quality of life. Nevertheless, ... Read more >>

Maedica (Bucur) (Maedica)
[2021, 16(1):54-63]

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Immunoinformatics driven construction of multi-epitope vaccine candidate against Ascaris lumbricoides using its entire immunogenic epitopes.

Rimanpreet Kaur, Naina Arora, Suraj Singh Rawat, Anand Kumar Keshri, Neha Singh, Sumit Kumar Show, Pramod Kumar, Amit Mishra, Amit Prasad,

<h4>Objective</h4><i>Ascaris lumbricoides</i> infects 80 million people per year, causing malnutrition, stunted growth of children etc., but there is no vaccine available against it. We aimed to design a multimeric-subunit vaccine using comprehensive immunoinformatic approach.<h4>Research design and methods</h4>The T and B cell epitopes were shortlisted on antigenicity, allergenicity, and toxicity from ... Read more >>

Expert Rev Vaccines (Expert review of vaccines)
[2021, :1-13]

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Autophagy based cellular physiological strategies target oncogenic progression.

Prashant Kumar, Yuvraj Anandrao Jagtap, Som Mohanlal Patwa, Sumit Kinger, Ankur Rakesh Dubey, Vijay Kumar Prajapati, Rohan Dhiman, Krishna Mohan Poluri, Amit Mishra,

Evidence accumulated from past findings indicates that defective proteostasis may contribute to risk factors for cancer generation. Irregular assembly of abnormal proteins catalyzes the disturbance of cellular proteostasis and induces the ability of abnormal cellular proliferation. The autophagy mechanism plays a key role in the regular clearance of abnormal/poor lipids, proteins, and ... Read more >>

J Cell Physiol (Journal of cellular physiology)
[2021, :]

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A Case of Transient Monocular Vision Loss and Paracentral Acute Middle Maculopathy.

Devin M Betsch, Amit V Mishra, Paul R Freund,

<h4>Abstract</h4>A 77-year-old man with multiple cerebrovascular risk factors presented with a history of transient monocular vision loss and residual paracentral visual disturbance in the right eye. Carotid ultrasounds, erythrocyte sedimentation rate, and C-reactive protein were all within normal limits. He was found to have retinal whitening within the macula in ... Read more >>

J Neuroophthalmol (Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society)
[2021, 41(3):e360-e362]

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Vaccine for a neglected tropical disease Taenia solium cysticercosis: fight for eradication against all odds.

Rimanpreet Kaur, Naina Arora, Suraj S Rawat, Anand Kumar Keshri, Shubha Rani Sharma, Amit Mishra, Gagandeep Singh, Amit Prasad,

<h4>Introduction</h4><i>Taenia solium</i> infection is among the 17 most neglected tropical diseases identified by World Health Organization and to be eradicated by 2030. This parasite infects the central nervous system (Neurocysticercosis [NCC]) and intestine [Taeniasis]). NCC is the most frequent cause of acquired epilepsy in endemic regions and Taeniasis is responsible ... Read more >>

Expert Rev Vaccines (Expert review of vaccines)
[2021, :1-12]

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Gore-Tex suture exposure following transscleral fixation of an intraocular lens.

André S Pollmann, Amit V Mishra, R Rishi Gupta,

Can J Ophthalmol (Canadian journal of ophthalmology. Journal canadien d'ophtalmologie)
[2021, :]

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Integration of Different Disciplines in Medicine: A Vertical Integrated Teaching Session for Undergraduate Medical Students.

Amit Kumar Mishra, Roselin Mohandas, Manikandan Mani,

<h4>Introduction</h4>The medical course is very vast and disciplines are covered in different phases. Most of the teaching methods are didactic and conducted by individual disciplines; that's why students fail to see the relevance of different disciplines and do not develop the required skills such as critical thinking, problem solving, and ... Read more >>

J Adv Med Educ Prof (Journal of advances in medical education & professionalism)
[2020, 8(4):172-177]

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Mechanism for antiParkinsonian effect of resveratrol: Involvement of transporters, synaptic proteins, dendrite arborization, biochemical alterations, ER stress and apoptosis.

Ashish Singh, Arun Kumar Yadawa, Swati Chaturvedi, M Wahajuddin, Amit Mishra, Sarika Singh,

The present study was undertaken to evaluate the mechanism for antiParkinsonian effect of resveratrol employing 6-hydroxydopamine (6-OHDA) induced experimental model of Parkinson's disease (PD). Resveratrol treatment significantly protects the PD related pathological markers like level of tyrosine hydroxylase, dopamine and apoptotic proteins (Bax and cleaved caspase-3). Disease pathology involves significantly ... Read more >>

Food Chem Toxicol (Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association)
[2021, 155:112433]

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Wilms' Tumor in Adults-Conventional and Unconventional Presentations of a Rare Entity with a Review of Literature.

Sujata Tripathi, Amit Mishra, Vijay C Popat, Syed Altaf Husain,

Wilms' tumor (WT) in adults is a rare neoplasm. Only a few reports are available in the literature. The tumor often masquerades as renal cell carcinoma (RCC). For accurate reporting, histopathological examination (HPE) plays a vital role in early diagnosis and prompt administration of multimodality treatment helps to improve the ... Read more >>

J Kidney Cancer VHL (Journal of kidney cancer and VHL)
[2021, 8(2):40-48]

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Herpesviruses and the hidden links to Multiple Sclerosis neuropathology.

Shweta Jakhmola, Arun Upadhyay, Khushboo Jain, Amit Mishra, Hem Chandra Jha,

Herpesviruses like Epstein-Barr virus, human herpesvirus (HHV)-6, HHV-1, VZV, and human endogenous retroviruses, have an age-old clinical association with multiple sclerosis (MS). MS is an autoimmune disease of the nervous system wherein the myelin sheath deteriorates. The most popular mode of virus mediated immune system manipulation is molecular mimicry. Numerous ... Read more >>

J Neuroimmunol (Journal of neuroimmunology)
[2021, 358:577636]

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P2X7 receptor in multifaceted cellular signalling and its relevance as a potential therapeutic target in different diseases.

Abtar Mishra, Assirbad Behura, Ashish Kumar, Lincoln Naik, Ashapoorna Swain, Mousumi Das, Suman Sudha Sarangi, Puja Dokania, Vijaya R Dirisala, Sujit K Bhutia, Amit Mishra, Ramandeep Singh, Rohan Dhiman,

P2X7 receptor, a purinergic receptor family member, is abundantly expressed on many cells, including immune, muscle, bone, neuron, and glia. It acts as an ATP-activated cation channel that permits the influx of Ca<sup>2+</sup>, Na<sup>+</sup> and efflux of K<sup>+</sup> ions. The P2X7 receptor plays crucial roles in many physiological processes including ... Read more >>

Eur J Pharmacol (European journal of pharmacology)
[2021, 906:174235]

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Selection of nitrogen responsive root architectural traits in spinach using machine learning and genetic correlations.

Henry O Awika, Amit K Mishra, Haramrit Gill, James DiPiazza, Carlos A Avila, Vijay Joshi,

The efficient acquisition and transport of nutrients by plants largely depend on the root architecture. Due to the absence of complex microbial network interactions and soil heterogeneity in a restricted soilless medium, the architecture of roots is a function of genetics defined by the soilless matrix and exogenously supplied nutrients ... Read more >>

Sci Rep (Scientific reports)
[2021, 11(1):9536]

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Venoarterial extra corporeal membrane oxygenation and blood component usage in pediatric patients undergoing cardiac surgery: Single centre experience.

Jigar Surti, Imelda Jain, Amit Mishra, Trushar Gajjar, Atul Solanki, Jigar Patel, Jatin Shah, Sapna Shah,

<h4>Background</h4>Extra Corporeal Membrane Oxygenation (ECMO) is a well-known tool for providing life-saving support in patients developing post cardiotomy cardiogenic shock in post cardiac surgeries. The current study was designed to evaluate blood transfusion requirements and its relation to mortality in neonate and pediatric cardiac patients requiring venoarterial cardiac ECMO during ... Read more >>

Ann Card Anaesth (Annals of cardiac anaesthesia)
[2021, 24(2):203-208]

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Rivastigmine attenuates the Alzheimer's disease related protein degradation and apoptotic neuronal death signalling.

Parul Gupta, Shubhangini Tiwari, Abhishek Singh, Amit Pal, Amit Mishra, Sarika Singh,

Rivastigmine is a clinical drug for patients of Alzheimer's disease (AD) exerting its inhibitory effect on acetylcholinesterase activity however, its effect on other disease-related pathological mechanisms are not yet known. This study was conducted to evaluate the effect of rivastigmine on protein aggregation and degradation related mechanisms employing streptozotocin (STZ) ... Read more >>

Biochem J (The Biochemical journal)
[2021, 478(7):1435-1451]

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Anesthetic and intensive care management of left main coronary artery to main pulmonary artery fistula diagnosed in postoperative case of tetralogy of fallot.

Suvendu Panda, Hemang Gandhi, Jigar Surti, Amit Mishra, Bhavik Champaneri,

Cases of coronary to pulmonary artery fistula are seen in patients of pulmonary atresia with ventricular septal defect (VSD). These fistulas are rarely seen in patients of Tetralogy of Fallot (TOF). In this case report, we have presented ICU management of a postoperative case of TOF, with missed diagnosis of ... Read more >>

Ann Card Anaesth (Annals of cardiac anaesthesia)
[2021, 24(2):272-274]

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Unilateral benign yellow dot maculopathy.

Amit V Mishra, André S Pollmann, Netan Choudhry, Erin Demmings, R Rishi Gupta,

<h4>Purpose</h4>To describe a unique case of unilateral benign yellow dot maculopathy.<h4>Observations</h4>A 25-year-man was evaluated after incidental finding of yellow dots in the right macula. The findings of examination and multimodal imaging were in keeping with a diagnosis of benign yellow dot maculopathy.<h4>Conclusions and importance</h4>Benign yellow dot maculopathy is a recently ... Read more >>

Am J Ophthalmol Case Rep (American journal of ophthalmology case reports)
[2021, 22:101068]

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Proteome Linked Biochemical Targets: Can Repair Defective Cellular Physiological Mechanisms?

Ankur Rakesh Dubey, Amit Prasad, Krishna Mohan Poluri, Amit Kumar, Awanish Kumar, Amit Mishra,

Major cause of proteopathies is the accumulation of unwanted mutant and aberrant proteins. We know that imperfect ageing is one of chief risk factor for most neurodegenerative diseases. Neurodegenerative diseases are characterized by mutant misfolded protein aggregates developing neural stress and debilitating several neuronal processes. Reducing the levels of these ... Read more >>

Cell Physiol Biochem (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology)
[2021, 55(S2):49-70]

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Spontaneous Resolution of A Retinal Nerve Fiber Layer Cyst.

Amit V Mishra, André S Pollmann, Netan Choudhry, Rudra Rishi Gupta,

Retina (Retina (Philadelphia, Pa.))
[2021, 41(3):e32-e34]

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Early diagnosis of diaphragm palsy after pediatric cardiac surgery and outcome after diaphragm plication - A single-center experience.

Divyakant Parmar, Jigar Panchal, Neha Parmar, Pankaj Garg, Amit Mishra, Jigar Surti, Kartik Patel,

<h4>Objective</h4>The aims of our prospective observational study were to evaluate the (1) reliability of clinical signs in the early detection of diaphragm palsy (DP); (2) reliability of ultrasonography using echo machine as a bedside tool for the diagnosis of DP; and (3) does early diaphragm plication result in the improved ... Read more >>

Ann Pediatr Cardiol (Annals of pediatric cardiology)
[2021, 14(2):178-186]

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Lack of evidence of association between ZNF408 variant and ROP.

Amit V Mishra, Johane M Robitaille,

Ophthalmic Genet (Ophthalmic genetics)
[2021, :1]

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Ibuprofen-based advanced therapeutics: breaking the inflammatory link in cancer, neurodegeneration, and diseases.

Arun Upadhyay, Ayeman Amanullah, Vibhuti Joshi, Rohan Dhiman, Vijay Kumar Prajapati, Krishna Mohan Poluri, Amit Mishra,

Ibuprofen is a classical nonsteroidal anti-inflammatory drug (NSAID) highly prescribed to reduce acute pain and inflammation under an array of conditions, including rheumatoid arthritis, osteoarthritis, dysmenorrhea, and gout. Ibuprofen acts as a potential inhibitor for cyclooxygenase enzymes (COX-1 and COX-2). In the past few decades, research on this small molecule ... Read more >>

Drug Metab Rev (Drug metabolism reviews)
[2021, 53(1):100-121]

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Complex Inclusion Bodies and Defective Proteome Hubs in Neurodegenerative Disease: New Clues, New Challenges.

Arun Upadhyay, Naveen Sundaria, Rohan Dhiman, Vijay Kumar Prajapati, Amit Prasad, Amit Mishra,

A healthy physiological environment of cells represents the dynamic homeostasis of crowded molecules. A subset of cellular proteome forms protein quality control (PQC) machinery to maintain an uninterrupted synthesis of new polypeptides and targeted elimination of old or defective proteins. The process of PQC may get overwhelmed under specific genetic ... Read more >>

Neuroscientist (The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry)
[2021, :1073858421989582]

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Surgical management of anomalous origin of coronary artery from pulmonary artery.

Amit Mishra,

<h4>Background</h4>Anomalous origin of coronary artery from pulmonary artery (AOCAPA), as is evident from the name, is defined as abnormal origin of either coronary artery from the pulmonary artery. The consequences vary in most cases and these anomalies lead to severe coronary hypo-perfusion and ventricular dysfunction. The common variants of this ... Read more >>

Indian J Thorac Cardiovasc Surg (Indian journal of thoracic and cardiovascular surgery)
[2021, :1-13]

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Nature and sources of ionic species in rainwater during monsoon periods in and around sixteenth-seventeenth century CE monuments in Yamuna River basin, India.

Amit Kumar Mishra, Anshumali,

The nature and sources of ionic species were studied in the monsoon rainwater collected from two monuments of the sixteenth-seventeenth century CE in the Yamuna River basin from 2016 to 2018. The results showed the acidic pH of the rainwater with high dissolved SO<sub>4</sub><sup>-2</sup> and NO<sub>3</sub><sup>-</sup>, and soil-derived components (Ca<sup>+2</sup>, ... Read more >>

Environ Monit Assess (Environmental monitoring and assessment)
[2021, 193(2):86]

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Cardinal role of eukaryotic initiation factor 2 (eIF2α) in progressive dopaminergic neuronal death & DNA fragmentation: Implication of PERK:IRE1α:ATF6 axis in Parkinson's pathology.

Sonam Gupta, Amit Mishra, Sarika Singh,

The study was conducted to assess the role of eukaryotic initiation factor 2 (eIF2α) in progressive dopaminergic neuronal death employing various interventions (YM08, 4μ8C, AEBSF, salubrinal, ursolic acid) of endoplasmic reticulum (ER) stress signaling. The protein level of all the ER stress related signaling factors (GRP78, IRE1α, ATF6, eIF2α, ATF4, ... Read more >>

Cell Signal (Cellular signalling)
[2021, 81:109922]

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