Full Text Journal Articles by
Author Alyssa Ziman

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To Reflex or Not to Reflex: A Time and Cost-Effectiveness Analysis of Autocontrol with Reflex DAT versus Direct DAT.

Trang Lollie, Voicu Suciu, Dawn C Ward, Alyssa Ziman, Andrea M McGonigle,

<h4>Objective</h4>Performing autocontrol with a reflex direct antiglobulin test (DAT) or directly performing IgG DAT only for alloantibody detection has been a matter of institutional preference. The aim of this study is to evaluate antibody identification (ABID), local cost, and staff time savings of both processes.<h4>Methods</h4>We retrospectively reviewed all positive indirect ... Read more >>

Lab Med (Laboratory medicine)
[2022, 53(1):53-57]

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IgM Warm Autoantibodies Causing Autoimmune Hemolytic Anemia in a Pediatric Patient.

Precious Fortes, Janet Baez, Andrea M McGonigle, Alyssa Ziman, Noah Federman, Dawn C Ward,

Most often, IgM-mediated autoimmune hemolytic anemia (AIHA) presents as cold agglutinin disease in the pediatric population. The IgM warm agglutinins are rare, with few reports in the literature. This case study describes a 5 year old girl with nausea, abdominal pain and jaundice, and a hemoglobin of 5.5 g/dL who ... Read more >>

Lab Med (Laboratory medicine)
[2021, :]

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Who donates? Patterns of blood donation and donor characteristics at a university-affiliated hospital-based donor center.

Mana Sheykhsoltan, Wesley Wu, Zhen Mei, Dawn C Ward, Alyssa Ziman,

<h4>Background</h4>Blood donors are a crucial element of the blood supply chain. Optimal recruitment strategies built upon the robust understanding of local donor behavior and demographics-specifically, the donor characteristics of our university-affiliated hospital-based donor center-improve outreach and retention of donors.<h4>Study design and methods</h4>This retrospective study analyzed blood donors' genders, ethnicities, and ... Read more >>

Transfusion (Transfusion)
[2021, :]

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Educational cost-effective intervention to reduce pathologist's peripheral blood smears reviews with non-contributory findings: an academic institution experience.

Trang K Lollie, Robyn Parks, Lissette Bakic, Alyssa Ziman, Sheeja Pullarkat,

Peripheral blood smear (PBS) review by a pathologist is a necessary and invaluable diagnostic tool. However, innovative highly sophisticated haematology analysers that flag peripheral blood abnormalities have decreased the need for a PBS review. Ordering practices including PBS reviews lumped as part of an 'order set' or with complete blood ... Read more >>

J Clin Pathol (Journal of clinical pathology)
[2021, :]

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International Forum on Home-Based Blood Transfusion: Responses.

Briony Shaw, Erica Wood, Zoe McQuilten, Jeannie Callum, Iñigo Romon, Pedro Sanroma, Dora Garcia, Philip Crispin, Lilian Castilho, Jose Mauro Kutner, Ana Paula Hitomi Yokoyama, Amalia Bravo, Emmanuel Fernandez Sanchez, Karla Maldonado Silva, Satyam Arora, Nita Radhakrishnan, Seema Dua, Alyssa Ziman, Agneta Wikman, Norbert Lubenow, Linda Bodecker Zingmark, Vernon Louw, Perry Loebenberg, Davinder Sidhu, Tara Redfern, Susan Nahirniak, Nancy Dunbar,

Vox Sang (Vox sanguinis)
[2021, :]

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Current state and positive impact of hospital-based blood donor centers in the United States.

Cyril Jacquot, Zhen Mei, Jenna Khan, Nancy Dunbar, Meghan Delaney, Alyssa Ziman,

<h4>Background</h4>The COVID-19 pandemic has brought tremendous challenges to the United States blood supply. Decreased collections have caused blood product shortages. The number of hospital-based donor centers (HBDCs) has decreased in the past decades, but they provide important support to their hospital systems.<h4>Materials/methods</h4>We identified 79 active HBDCs through an information request ... Read more >>

Transfusion (Transfusion)
[2021, :]

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False anemia due to total parenteral nutrition and lipid emulsion contamination.

Sofia Liou, Lissette Bakic, Bethelhem Manakelew, Floricel Guillermo, Andrea M McGonigle, Alyssa Ziman, Dawn C Ward, Zhen Mei,

Transfusion (Transfusion)
[2022, 62(1):14-15]

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International Forum on Home-Based Blood Transfusion: Summary.

Briony Shaw, Erica Wood, Zoe McQuilten, Jeannie Callum, Iñigo Romon, Pedro Sanroma, Dora Garcia, Philip J Crispin, Lilian Castilho, Jose Mauro Kutner, Ana Paula Hitomi Yokoyama, Amalia Bravo, Emmanuel Fernandez Sanchez, Karla Maldonado Silva, Satyam Arora, Nita Radhakrishnan, Seema Dua, Alyssa Ziman, Agneta Wikman, Norbert Lubenow, Linda Bodecker Zingmark, Vernon J Louw, Perry Loebenberg, Davinder Sidhu, Tara Redfern, Susan Nahirniak, Nancy Dunbar,

Vox Sang (Vox sanguinis)
[2021, :]

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A pilot study of stored low titer group O whole blood + component therapy versus component therapy only for civilian trauma patients.

Anaar E Siletz, Kevin J Blair, Richelle J Cooper, N Charity Nguyen, Scott J Lewis, Amy Fang, Dawn C Ward, Nicholas J Jackson, Tyler Rodriguez, Jonathan Grotts, Jonathan Hwang, Alyssa Ziman, Henry Magill Cryer,

<h4>Background</h4>This pilot assessed transfusion requirements during resuscitation with whole blood followed by standard component therapy (CT) versus CT alone, during a change in practice at a large urban Level I trauma center.<h4>Methods</h4>This was a single-center prospective cohort pilot study. Male trauma patients received up to 4 units of cold-stored low ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2021, 91(4):655-662]

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Pathogen-reduced platelets in pediatric and neonatal patients: Demographics, transfusion rates, and transfusion reactions.

Baia Lasky, Joseph Nolasco, Jazmin Graff, Dawn C Ward, Alyssa Ziman, Andrea M McGonigle,

<h4>Background</h4>Pathogen-reduced platelets (PR PLT) are the emerging standard for proactive transfusion-transmitted infection (TTI) mitigation. There is, however, continued hesitation to transfuse PR PLT in children due to limited published data. We report demographics, rates of transfusion, and transfusion reactions (TR) associated with FDA-approved PR PLT in pediatric and neonatal patients ... Read more >>

Transfusion (Transfusion)
[2021, 61(10):2869-2876]

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Too lean: Time to build back true resiliency in the national blood supply.

Sarah Barnhard, Ellen Klapper, Patricia Kopko, Minh-Ha Tran, Alyssa Ziman, ,

Transfusion (Transfusion)
[2021, 61(9):2768-2771]

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The safety of COVID-19 convalescent plasma donation: A multi-institutional donor hemovigilance study.

Joseph H Cho, Srijana Rajbhandary, Nancy L van Buren, Mark K Fung, Maha Al-Ghafry, Joy L Fridey, Beth A Dy, Alyssa Ziman, George B Schreiber, Richard R Gammon, Rita Reik, James R Stubbs, Camille M van Buskirk, Hany Kamel, Mary J Townsend, Michelle P Zeller, Jerome L Gottschall,

<h4>Background</h4>Although the safety and therapeutic efficacy of COVID-19 convalescent plasma (CCP) has been extensively evaluated, the safety of CCP donation has not been explored in a multi-institutional context.<h4>Study design and methods</h4>Nine blood collection organizations (BCOs) participated in a multi-institutional donor hemovigilance effort to assess the safety of CCP donation. Donor ... Read more >>

Transfusion (Transfusion)
[2021, 61(9):2668-2676]

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Macroscopic and microscopic visual inspection of a formed clot in a cryoprecipitate unit.

Zhen Mei, Andrea M McGonigle, Dawn Ward, Alyssa Ziman,

Transfusion (Transfusion)
[2021, 61(9):2526-2527]

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How do we implement pathogen reduction technology, while maintaining an adequate platelet inventory for our patients?

Jennifer T Nguyen, Jowin Rioveros, Alyssa Ziman, Andrea M McGonigle, Dawn C Ward,

Despite the significantly reduced infectious disease risk through robust and sensitive laboratory assays, comprehensive donor screening and good manufacturing practices, new and emerging infectious agents and bacterial contamination continue to pose a threat to the blood supply. Pathogen Reduction (PR) technology is an option to mitigate the risk of platelet ... Read more >>

Transfusion (Transfusion)
[2021, 61(4):1014-1022]

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Optimizing Inpatient Blood Utilization Using Real-Time Clinical Decision Support.

Shohei Ikoma, Meg Furukawa, Ashley Busuttil, Dawn Ward, Kevin Baldwin, Jeffrey Mayne, Robin Clarke, Alyssa Ziman,

<h4>Background</h4>Red blood cell (RBC) transfusion is a common medical procedure. While it offers clinical benefits for many, hemodynamically stable patients are often subjected to unwarranted transfusions, with the potential to lead to adverse consequences. We created a real-time clinical decision support (CDS) tool in the electronic health record system to ... Read more >>

Appl Clin Inform (Applied clinical informatics)
[2021, 12(1):49-56]

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Transfusion of blood components containing ABO-incompatible plasma does not lead to higher mortality in civilian trauma patients.

Jansen N Seheult, Nancy M Dunbar, John R Hess, Erin E Tuott, Mohammad Bahmanyar, Jessica Campbell, Magali Fontaine, Jenna Khan, Ara Ko, Jian Mi, Michael F Murphy, Tara Nykoluk, Jessica Poisson, Jay S Raval, Andrew Shih, Jason L Sperry, Julie Staves, Michelle Wong, Matthew T S Yan, Alyssa Ziman, Mark H Yazer, ,

<h4>Background</h4>This study investigated the effect on mortality of transfusing ABO-incompatible plasma from all sources during trauma resuscitation.<h4>Methods</h4>Demographic, transfusion, and survival data were retrospectively extracted on civilian trauma patients. Patients were divided by receipt of any quantity of ABO-incompatible plasma from any blood product (incompatible group) or receipt of solely ABO-compatible ... Read more >>

Transfusion (Transfusion)
[2020, 60(11):2517-2528]

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Red-blood-cell alloimmunization and prophylactic antigen matching for transfusion in patients with warm autoantibodies.

Meghan Delaney, Torunn Oveland Apelseth, Carolina Bonet Bub, Claudia S Cohn, Nancy M Dunbar, Jose Mauro Kutner, Michael Murphy, Iris Perelman, Kathleen Selleng, Julie Staves, Silvano Wendel, Alyssa Ziman, ,

<h4>Background</h4>Warm autoantibodies (WAA) are antibodies that react with an antigen on a patient's own red-blood-cells and can complicate compatibility testing whether or not they cause clinical haemolysis. The goal of this study was to understand the overall prevalence of WAA, the risk of RBC alloimmunization and determine whether RBC selection ... Read more >>

Vox Sang (Vox sanguinis)
[2020, 115(6):515-524]

Cited: 1 time

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Noninterruptive Clinical Decision Support Decreases Ordering of Respiratory Viral Panels during Influenza Season.

Cameron Escovedo, Douglas Bell, Eric Cheng, Omai Garner, Alyssa Ziman, Sitaram Vangala, Prabhu Gounder, Carlos Lerner,

<h4>Objective</h4>A growing body of evidence suggests that testing for influenza virus alone is more appropriate than multiplex respiratory viral panel (RVP) testing for general populations of patients with respiratory tract infections. We aimed to decrease the proportion of RVPs out of total respiratory viral testing ordered during influenza season.<h4>Methods</h4>We implemented ... Read more >>

Appl Clin Inform (Applied clinical informatics)
[2020, 11(2):315-322]

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Transfusion of Uncrossmatched Group O Erythrocyte-containing Products Does Not Interfere with Most ABO Typings.

Mark H Yazer, Philip C Spinella, Leilani Doyle, Richard M Kaufman, Robyn Dunn, John R Hess, Luiz Amorim Filho, Magali Fontaine, Birgit Gathof, Bryon Jackson, Michael F Murphy, Jeremiah Pasion, Jay S Raval, Kristin Rosinski, Jansen Seheult, Andrew W Shih, Jason Sperry, Julie Staves, Erin E Tuott, Alyssa Ziman, Darrell J Triulzi, ,

<h4>Background</h4>Group O erythrocytes and/or whole blood are used for urgent transfusions in patients of unknown blood type. This study investigated the impact of transfusing increasing numbers of uncrossmatched type O products on the recipient's first in-hospital ABO type.<h4>Methods</h4>This was a retrospective cohort study. Results of the first ABO type obtained ... Read more >>

Anesthesiology (Anesthesiology)
[2020, 132(3):525-534]

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Resolving Blocked Antigen Phenomenon in Hemolytic Disease of the Fetus and Newborn Due to Anti-K.

Mitchell Moosavi, Yao Ma, Janet Baez, Rebecca Jeffreys, Dawn C Ward, Alyssa Ziman, Andrea M McGonigle,

High-titer antibodies are a cause of false-negative reactions in red blood cell antigen phenotyping, an event referred to as blocked antigen phenomenon (BAP). In hemolytic disease of the fetus and newborn, BAP complicates laboratory workups as fetal phenotype is helpful in confirming the responsible antibody. Acid elution techniques, techniques using ... Read more >>

Transfus Med Rev (Transfusion medicine reviews)
[2020, 34(2):124-127]

Cited: 1 time

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How do you… decide which platelet bacterial risk mitigation strategy to select for your hospital-based transfusion service?

Wen Lu, Meghan Delaney, Willy A Flegel, Paul Ness, Nora Ratcliffe, Darrell J Triulzi, Mark H Yazer, Alyssa Ziman, Nancy M Dunbar,

The United States Food and Drug Administration Final Guidance for Industry titled, "Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion" provides nine strategies for platelet bacterial risk mitigation. Even if it is assumed all strategies are comparable ... Read more >>

Transfusion (Transfusion)
[2020, 60(4):675-681]

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Impact of Age of Packed RBC Transfusion on Oxygenation in Patients Receiving Extracorporeal Membrane Oxygenation.

Sumit Datta, Shelley Chang, Nicholas J Jackson, Alyssa Ziman, Myke Federman,

<h4>Objective</h4>To determine the effect of age of packed RBCs on tissue oxygenation in children receiving extracorporeal membrane oxygenation support.<h4>Design</h4>A retrospective study was done between March 2013 and August 2015. The following biomarkers were examined 6 hours before and 6 hours after the conclusion of a transfusion: serum and circuit hematocrits, ... Read more >>

Pediatr Crit Care Med (Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies)
[2019, 20(9):841-846]

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The BEST criteria improve sensitivity for detecting positive cultures in residual blood components cultured in suspected septic transfusion reactions.

Andrew W Shih, Claudia S Cohn, Meghan Delaney, Magali J Fontaine, Isabella Martin, Nancy M Dunbar, ,

<h4>Background</h4>Culturing residual blood components after suspected septic transfusion reactions guides management of patients and cocomponents. Current practice, accuracy of provider vital sign assessment, and performance of the AABB culture criteria are unknown. A multicenter international study was undertaken to investigate these issues and develop improved culture criteria.<h4>Study design and methods</h4>Retrospective ... Read more >>

Transfusion (Transfusion)
[2019, 59(7):2292-2300]

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Comparison of titer results obtained using immediate spin one-dilution techniques to a reference method.

Mark H Yazer, Nancy M Dunbar, Carolina Bonet Bub, Brittany E Condict, Robyn Dunn, Miloslava Janoušková, Jose Kutner, Ludmila Landová, Hana Lejdarová, Božena Nesvačilová, Rita Pacasová, Renata Procházková, Lenka Řehořová, Jay S Raval, Alyssa Ziman, Miloš Bohonĕk,

<h4>Background</h4>Many transfusion services determine the titer of potentially incompatible plasma-containing products by performing a one-dilution titer at their selected titer threshold. This study compared the results of immediate spin (IS) one-dilution titers determined by three methods with a reference standard method.<h4>Methods</h4>Plasma-containing products from group A and O donors were titered ... Read more >>

Transfusion (Transfusion)
[2019, 59(S2):1512-1517]

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Safety of blood donation by individuals over age 70 and their contribution to the blood supply in five developed countries: a BEST Collaborative group study.

Mindy Goldman, Marc Germain, Yves Grégoire, Ralph R Vassallo, Hany Kamel, Marjorie Bravo, David O Irving, Emanuele Di Angelantonio, Whitney R Steele, Sheila F O'Brien, ,

<h4>Background</h4>Some countries impose an upper age limit on whole blood and double RBC donation while others do not. We evaluated the safety of blood donation in older individuals (≥71 years), and their contribution to the blood supply of five countries.<h4>Study design and methods</h4>Twelve blood center members of the Biomedical Excellence ... Read more >>

Transfusion (Transfusion)
[2019, 59(4):1267-1272]

Cited: 4 times

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