Full Text Journal Articles by
Author Alpay Azap

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Does SARS-CoV-2 reach peritoneal effluent?

Rezzan Eren Sadioglu, Merve Aktar, Ezgi Gulten, Sahin Eyupoglu, Zeynep Ceren Karahan, Alpay Azap, Sule Sengul, Kenan Ates, Sim Kutlay,

Perit Dial Int (Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis)
[2020, 40(5):520-521]

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Pattern of systemic antibiotic use and potential drug interactions: Evaluations through a point prevalence study in Ankara University Hospitals.

İrem Akdemİr Kalkan, GÜle Çinar, Aysel Pehlİvanli, Fatİh Ürkmez, İzel Ezgİ TopaloĞlu, BÜŞra Akyol, Arzu BeŞİkcİ, Alpay Azap, Kemal Osman MemİkoĞlu,

Background/Aim Most of the hospitalized patients are on a number of drugs for comorbidities and/or to prevent nosocomial infections. This necessitates a careful consideration of drug interactions not only to avoid possible toxicities but also to reach the highest efficiency with drug treatment. We aimed to investigate drug interactions related ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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[Management of obstructive sleep apnea during COVID-19 pandemic].

Banu Gülbay, Alpay Azap, Akın Kaya, Turan Acıcan,

Coronavirus disease 2019 (COVID-19) is an infectious disease that causes important mortality and morbidity all over the world caused by SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), which started in China at the end of 2019. It spreads rapidly, mainly through droplets, and especially for all healthcare workers involved in ... Read more >>

Tuberk Toraks (Tuberkuloz ve toraks)
[2020, 68(2):135-140]

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Clinical course of COVID-19 infection in elderly patient with melanoma on nivolumab.

Emre Yekedüz, Bengü Dursun, Güle Ç Aydın, Satı C Yazgan, Halis H Öztürk, Alpay Azap, Güngör Utkan, Yüksel Ürün,

Outbreak of the new type coronavirus infection, known as coronavirus infection 2019 (COVID-19), has begun in December 2019, in Wuhan, China. As of today, 3 April 2020, 972,640 people affected and 50,325 people died from Severe Acute Respiratory Syndrome-Coronavirus 2. There is not any standard treatment for coronavirus infection 2019; ... Read more >>

J Oncol Pharm Pract (Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners)
[2020, 26(5):1289-1294]

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Regulatory consideration on preparation and clinical use of COVID-19 convalescent plasma.

Soner Yılmaz, Nigar Ertuğrul Örüç, Osman İlhami Özcebe, Alpay Azap, Ahmet Türker Çetin, İdil Yenicesu, Abdullah Öztürk, Mehmet Gündüz, Ahmet Tekin,

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease (COVID-19), spreading from Wuhan to worldwide has been emerged since December 2019. Although scientists and researchers have been racing to develop specific therapeutic agents or vaccines against SARS-CoV-2 since the identification of the agent, either a drug or ... Read more >>

Transfus. Apher. Sci. (Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis)
[2020, :102846]

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Medical mask or N95 respirator: When and how to use?

Alpay Azap, F Şebnem Erdinç,

COVID-19 pandemic is now a global threat to human health reaching up to 2 million infected people all around the world. Since its first recognition in Wuhan, many topics were discussed intensively about COVID-19, both in ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2020, 50(SI-1):633-637]

Cited: 1 time

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Stage I-laparoscopy partial ALPPS procedure for perihilar cholangiocarcinoma.

Deniz Balci, Elvan Onur Kirimker, Evren Üstüner, Ali Abbas Yilmaz, Alpay Azap,

The treatment for perihilar cholangiocarcinoma (PHC) is a challenge for the surgeon requiring complex resections with a reported perioperative mortality rate between 15% and 48%. In PHC patients with future liver remnant (FLR) less than 30%, it is advised that hepatectomy can be safely performed after the FLR is modified. ... Read more >>

J Surg Oncol (Journal of surgical oncology)
[2020, 121(6):1022-1026]

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Carbapenemase-Producing Bacterial Infections in Patients With Liver Transplant.

Gule Cinar, İrem Akdemir Kalkan, Alpay Azap, Onur Elvan Kirimker, Deniz Balci, Onur Keskin, Cihan Yuraydin, Necati Ormeci, Abdulkadir Dokmeci,

Carbapenemase-producing Enterobacteriacea (CPE) cause serious and life-threatening infections. They are resistant to carbapenems and many other classes of commonly used antimicrobial agents; therefore, managing infections caused by them poses a substantial challenge in clinical practice. They can also cause morbidity and mortality in patients with liver transplant. A retrospective analysis ... Read more >>

Transplant. Proc. (Transplantation proceedings)
[2019, 51(7):2461-2465]

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Effect of Pretransplant Infections on Clinical Outcomes in Live-Donor Liver Transplant Recipients.

Gule Cinar, İrem Akdemir Kalkan, Alpay Azap, Onur Elvan Kirimker, Deniz Balci, Onur Keskin, Cihan Yuraydin, Necati Ormeci, Abdulkadir Dokmeci,

Owing to impaired immune function, surgical procedures, and multiple hospitalizations, patients with end-stage liver disease are at risk for numerous infectious complications while waiting for transplantation. Infection in transplant recipients remains the main cause of mortality and morbidity, despite advances in surgical techniques and the development of new repressive agents. ... Read more >>

Transplant. Proc. (Transplantation proceedings)
[2019, 51(7):2434-2438]

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Vaccination of adults with heart failure and chronic heart conditions: Expert opinion.

Ahmet Çelik, Hakan Altay, Alpay Azap, Yüksel Çavuşoğlu, Sanem Nalbantgil, Esin Şenol, Ahmet Temizhan, Mehmet Birhan Yılmaz,

Turk Kardiyol Dern Ars (Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir)
[2018, 46(8):723-734]

Cited: 0 times

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Impact of the ST101 clone on fatality among patients with colistin-resistant Klebsiella pneumoniae infection.

Fusun Can, Sirin Menekse, Pelin Ispir, Nazli Atac, Ozgur Albayrak, Tuana Demir, Doruk Can Karaaslan, Salih Nafiz Karahan, Mahir Kapmaz, Ozlem Kurt Azap, Funda Timurkaynak, Serap Simsek Yavuz, Seniha Basaran, Fugen Yoruk, Alpay Azap, Safiye Koculu, Nur Benzonana, Nathan A Lack, Mehmet Gönen, Onder Ergonul,

Objectives:We describe the molecular characteristics of colistin resistance and its impact on patient mortality. Methods:A prospective cohort study was performed in seven different Turkish hospitals. The genotype of each isolate was determined by MLST and repetitive extragenic palindromic PCR (rep-PCR). Alterations in mgrB were detected by sequencing. Upregulation of pmrCAB, ... Read more >>

J. Antimicrob. Chemother. (The Journal of antimicrobial chemotherapy)
[2018, 73(5):1235-1241]

Cited: 5 times

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An Unexpected Fatal CCHF Case and Management of Exposed Health Care Workers.

Goksel Guven, Leyla Talan, Neriman Defne Altintas, Kemal Osman Memikoglu, Fugen Yoruk, Alpay Azap,

Crimean-Congo hemorrhagic fever (CCHF) is a tick borne viral disease which can also be transmitted by direct contact with blood or tissue specimens of infected animals or humans. We present a fatal case of CCHF, who was diagnosed after death, and describe the post-exposure management plan for the health care ... Read more >>

Int. J. Infect. Dis. (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2017, 55:118-121]

Cited: 3 times

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Diagnosis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-2).

Sevtap Arıkan Akdağlı, Alpay Azap, Figen Başaran Demirkazık, Beyza Ener, Sibel Aşcıoğlu Hayran, Özlem Özdemir Kumbasar, Gökhan Metan, Zekaver Odabaşı, Ömrüm Uzun, Hamdi Akan,

One of the most problematic issues in hematological malignancies is the diagnosis of invasive fungal diseases. Especially, the difficulty of mycological diagnosis and the necessity of immediate intervention in molds have led to the adoption of "surrogate markers" that do not verify but rather strongly suggest fungal infection. The markers ... Read more >>

Turk J Haematol (Turkish journal of haematology : official journal of Turkish Society of Haematology)
[2014, 31(4):342-356]

Cited: 0 times

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D-index: A New Scoring System in Febrile Neutropenic Patients for Predicting Invasive Fungal Infections.

Gülden Yılmaz, Belgin Coşkun, Atilla Elhan, Alpay Azap, Hamdi Akan,

Neutropenia is a critical risk factor for invasive fungal infections (IFIs). We retrospectively performed this study to assess the performance of the D-index, a new test that combines both the duration and the severity of neutropenia, in predicting IFIs among patients with acute myelogenous leukemia. 
Fifteen patients with IFIs and ... Read more >>

Turk J Haematol (Turkish journal of haematology : official journal of Turkish Society of Haematology)
[2016, 33(2):102-106]

Cited: 0 times

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How Does Influenza A (H1N1) Infection Proceed in Allogeneic Stem Cell Transplantation Recipients?

Sinem Civriz Bozdağ, Gülden Bozkurt, Pervin Topçuoğlu, Alpay Azap, Muhit Ozcan, Nahide Konuk, Onder Arslan,

The clinical course of influenza A (H1N1) infection in allogeneic hematopoietic stem cell transplantation (AHSCT)recipients is not clearly known. We report 3 AHSCT recipients that were infected with influenza A (H1N1). Each of thepatients had a different hematological disease and was at a different post-transplantation stages. All the patients weretreated ... Read more >>

Turk J Haematol (Turkish journal of haematology : official journal of Turkish Society of Haematology)
[2012, 29(1):63-66]

Cited: 0 times

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Secondary infections in cancer patients with febrile neutropenia.

Alpay Azap, Gülden Yılmaz Bozkurt, Meltem Kurt Yüksel, Hakan Kutlu, Pervin Topçuoğlu, Adalet Aypak, Hamdi Akan,

OBJECTIVE: Patients with neutropenia due to cancer chemotherapy are prone to severe infections. Cancer patients canexperience >1 infectious episode during the same period of neutropenia. This study aimed to determine the etiologicaland clinical characteristics of secondary infectious episodes in cancer patients with febrile neutropenia and to identifythe factors associated with ... Read more >>

Turk J Haematol (Turkish journal of haematology : official journal of Turkish Society of Haematology)
[2012, 29(3):254-258]

Cited: 1 time

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The impact of a nationwide antibiotic restriction program on antibiotic usage and resistance against nosocomial pathogens in Turkey.

Adalet Altunsoy, Cenk Aypak, Alpay Azap, Önder Ergönül, Ismail Balık,

PURPOSE:Antimicrobial resistance among microorganisms is a global concern. In 2003, a nationwide antibiotic restriction program (NARP) was released in Turkey. In this study we evaluated the effect of NARP on antibiotic consumption, antimicrobial resistance, and cost. MATERIALS AND METHODS:The data obtained from all of the four university hospitals, and one ... Read more >>

Int J Med Sci (International journal of medical sciences)
[2011, 8(4):339-344]

Cited: 13 times

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Vaccination against pandemic influenza A H1N1 among health care workers. Lessons for the next pandemic.

Alpay Azap, Gülden Y Bozkurt, Fehminaz Temel, Banu Çakir, Sebahat Tezcan,

Saudi Med J (Saudi medical journal)
[2011, 32(8):858-860]

Cited: 0 times

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A case of brucellosis presenting with multiple hypodense splenic lesions and bilateral pleural effusions.

Emine Dilek Eruz, Serhat Birengel, Alpay Azap, Gulden Yilmaz Bozkurt,

Brucellosis is a zoonotic infectious disease, which mainly present with lymphoreticular system invovement. However any organ system can be attacked by the microorganism. In this paper we present a 52-year-old female patient who was admitted to the Infectious Diseases Department with complaints of fatigue, arthralgias, fever, and weight loss. In ... Read more >>

(Case reports in medicine)
[2011, 2011:614546]

Cited: 5 times

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A case of brucellar monoarthritis and review of the literature.

Ethem Turgay Cerit, Murat Aydın, Alpay Azap,

Brucellosis is a systemic infectious disease, which constitutes a public health problem in Turkey. Brucellosis has a broad spectrum of clinical manifestations. Osteoarthicular manifestations are often seen in brucellosis but most of the brucellar monoarthritis cases are reactive rather than being septic. We report a case of brucellar (septic) monoarthritis ... Read more >>

Rheumatol. Int. (Rheumatology international)
[2012, 32(5):1465-1468]

Cited: 6 times

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Tuberculosis of the breast in a patient undergoing hemodialysis.

Ozan Yazici, Pinar Mescigil, Ilknur Kepenekci, Pinar Celepli, Sule Sengul, Alpay Azap, Sehsuvar Ertürk,

A 61-year-old female patient with diabetes undergoing maintenance hemodialysis presented with fever and swelling of her right breast. She had been unresponsive to nonspecific antimicrobial therapies. Breast tuberculosis and tuberculous lymphadenitis were diagnosed by excision biopsy and tissue culture. A combination antituberculous treatment including isoniazid, rifampin, ethambutol, and pyrazinamide was ... Read more >>

Int Urol Nephrol (International urology and nephrology)
[2011, 43(1):241-244]

Cited: 1 time

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[Mupirocin resistance in methicillin-resistant Staphylococcus aureus strains isolated from wound infections].

Istar Dolapçi, Z Ceren Karahan, Alper Tekeli, Esra Koyuncu, Alpay Azap, Riza Adaleti,

Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as an important pathogen in community-acquired and nosocomial infections. The unique bactericidal action of mupirocin makes it one of the few antibiotics still effective against MRSA. The purpose of this study was to investigate the mupirocin resistance in MRSA strains isolated from wound infections ... Read more >>

Mikrobiyol Bul (Mikrobiyoloji bulteni)
[2007, 41(3):435-440]

Cited: 1 time

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Meningoencephalitis, pancytopenia, pulmonary insufficiency and splenic abscess in a patient with brucellosis.

Fugen Cokca, Gulden Yilmaz-Bozkurt, Alpay Azap, Osman Memikoglu, Emin Tekeli,

A complicated case of brucellosis with some rare features is reported. Brucellosis is a multisystemic disease. However, disseminated brucellosis with cerebral, pulmonary, hematopoietic and splenic involvement in an otherwise healthy patient is a rare event. In this article, we report a case of disseminated brucellosis who was initially diagnosed as ... Read more >>

Saudi Med J (Saudi medical journal)
[2006, 27(4):539-541]

Cited: 3 times

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The effect of a nationwide antibiotic restriction policy on antibiotic usage in a stem cell transplantation unit.

Alpay Azap, Pervin Topçuoğlu, Ayşegül Yeşilkaya, Mutlu Arat, Osman Memikoğlu, Özay Akan, Halil Kurt, Emin Tekeli, Hamdi Akan,

The Turkish Ministry of Health has released a regulation in February 2003 in order to decrease, first the antibiotic expenses and second, inappropriate use of antimicrobial agents. The aim of this study is to assess the impact of this nationwide antibiotic restriction (NAR) in the most active stem cell transplantation ... Read more >>

Turk J Haematol (Turkish journal of haematology : official journal of Turkish Society of Haematology)
[2005, 22(2):87-90]

Cited: 2 times

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Revised definition of 'fever of unknown origin': limitations and opportunities.

Onder Ergönül, Ayşe Willke, Alpay Azap, Emin Tekeli,

AIM: The limitations and opportunities of revised definition of fevers of unknown origin (FUO) in comparison to conventional definition were investigated, and prehospital characteristics of the patients were detailed. METHOD: The patients were grouped according to both revised and classic definitions of FUO. RESULTS: Fifty-nine of the 80 patients (74%) ... Read more >>

J. Infect. (The Journal of infection)
[2005, 50(1):1-5]

Cited: 25 times

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