Full Text Journal Articles by
Author Alice Ryan

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Relationship Between Nutrition Intake and Outcome After Subarachnoid Hemorrhage: Results From the International Nutritional Survey.

Neeraj Badjatia, Alice Ryan, H Alex Choi, Gunjan Y Parikh, Xuran Jiang, Andrew G Day, Daren K Heyland,

<h4>Background</h4>A previous study suggested an association between low caloric intake(CI), negative nitrogen balance, and poor outcome after subarachnoid hemorrhage(SAH). Objective of this multinational, multicenter study was to investigate whether clinical outcomes vary by protein intake(PI) or CI in SAH patients adjusting for the nutritional risk as judged by the modified ... Read more >>

J Intensive Care Med (Journal of intensive care medicine)
[2021, 36(10):1141-1148]

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Depressive symptom heterogeneity among older adults after hip fracture.

Jennifer M Kirk, Jay Magaziner, Michelle D Shardell, Alice S Ryan, Ann L Gruber-Baldini, Denise Orwig, Marc C Hochberg, Alan M Rathbun,

<h4>Objective</h4>to evaluate patterns of depressive symptoms after hip fracture and examine their impact on functional recovery.<h4>Methods</h4>participants (n = 304) included older adults from the Baltimore Hip Studies 7th cohort who experienced a hip fracture. Depressive symptoms were measured at baseline or 2-, 6- or 12-month post-hip fracture using the 20-item Center for ... Read more >>

Age Ageing (Age and ageing)
[2021, :]

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Bone Mineral Density Changes during Weight Regain following Weight Loss with and without Exercise.

Monica C Serra, Alice S Ryan,

The purpose of this study was to compare changes in bone mineral density (BMD) over a 6 month follow up (period of weight regain) in overweight, postmenopausal women having previously completed a 6 month weight loss (WL) intervention with and without aerobic exercise (AEX). Women (BMI > 25 kg/m<sup>2</sup>) underwent ... Read more >>

Nutrients (Nutrients)
[2021, 13(8):]

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Low Healthy Eating Index-2015 Is Associated With Sarcopenia Among US Adult Population

Galya Bigman, Alice Ryan,

Abstract <h4>Objectives</h4> The Healthy Eating Index-2015 (HEI-2015), which is designed to reflect the 2015–2020 Dietary Guidelines for Americans (DGA), and its association with muscle function decline (i.e., sarcopenia) is less known in the U.S. Our study aim was to examine the associations between HEI-2015 component and total scores with sarcopenia ... Read more >>

Curr Dev Nutr (Current developments in nutrition)
[2021, 5(Suppl 2):395-395]

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Effects of exercise training with weight loss on skeletal muscle expression of angiogenic factors in overweight and obese older men.

William S Evans, Jacob B Blumenthal, James M Heilman, Alice S Ryan, Steven J Prior,

Low skeletal muscle capillarization is associated with impaired glucose tolerance (IGT); however, aerobic exercise training with weight loss (AEX + WL) increases skeletal muscle capillarization and improves glucose tolerance in adults with IGT. Given that the expression of angiogenic growth factors mediates skeletal muscle capillarization, we sought to determine whether ... Read more >>

J Appl Physiol (1985) (Journal of applied physiology (Bethesda, Md. : 1985))
[2021, 131(1):56-63]

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Telehealth Exercise Intervention in Older Adults With HIV: Protocol of a Multisite Randomized Trial.

Krisann K Oursler, Vincent C Marconi, Brandon C Briggs, John D Sorkin, Alice S Ryan, ,

<h4>Abstract</h4>People with HIV (PWH) have reduced cardiorespiratory fitness, but a high intensity, easily disseminated exercise program has not yet been successfully developed in older PWH. The purpose of this article is to describe a synchronous telehealth exercise intervention in older PWH, delivered from one medical center to two other centers. ... Read more >>

J Assoc Nurses AIDS Care (The Journal of the Association of Nurses in AIDS Care : JANAC)
[2021, :]

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CD31+ Circulating Angiogenic Cell Number and Subtypes are Reduced in Individuals with Chronic Stroke.

Rian Q Landers-Ramos, Katherine I Kim, Brent Hickey, Frederick M Ivey, Charlene E Hafer-Macko, Richard F Macko, Alice S Ryan, Steven J Prior,

<h4>Background and purpose</h4>Reduced number and function of CD31+ circulating angiogenic cells (CACs) may explain vascular complications associated with the chronic phase stroke. The purpose of this study was to quantify CD31+ CAC paracrine function, total number and number of various subtypes of CD31+ CACs in individuals with chronic stroke compared ... Read more >>

Curr Neurovasc Res (Current neurovascular research)
[2021, 18(1):113-122]

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Physical performance measures in older women with urinary incontinence: pelvic floor disorder or geriatric syndrome?

Tatiana V D Sanses, Sharee Pearson, Derik Davis, Chi Chiung Grace Chen, Soren Bentzen, Jack Guralnik, Holly E Richter, Alice S Ryan,

<h4>Introduction and hypothesis</h4>To evaluate physical performance measures of mobility and functional impairments and assess their association with urinary incontinence (UI) severity and impact on quality of life among older women with UI.<h4>Methods</h4>In a cross-sectional pilot study, 20 women aged ≥ 70 years with UI completed UI questionnaires (Global Impression of Severity, ... Read more >>

Int Urogynecol J (International urogynecology journal)
[2021, 32(2):305-315]

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Insulin Resistance in Skeletal Muscle of Chronic Stroke.

Alice S Ryan, Charlene Hafer-Macko, Heidi K Ortmeyer,

A stroke can lead to reduced mobility affecting skeletal muscle mass and fatty infiltration which could lead to systemic insulin resistance, but this has not been examined and the mechanisms are currently unknown. The objective was to compare the effects of in vivo insulin on skeletal muscle glycogen synthase (GS) ... Read more >>

Brain Sci (Brain sciences)
[2020, 11(1):]

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Relationship Between Depression and Disease Activity in United States Veterans With Early Rheumatoid Arthritis Receiving Methotrexate.

Alan M Rathbun, Bryant R England, Ted R Mikuls, Alice S Ryan, Jennifer L Barton, Michelle D Shardell, Marc C Hochberg,

<h4>Objective</h4>Depression is common in patients with rheumatoid arthritis (RA), exacerbates disease activity, and may decrease response to first-line disease-modifying antirheumatic drugs. This study aimed to determine if depression affects disease activity among veterans with early RA prescribed methotrexate (MTX).<h4>Methods</h4>Participants included veterans enrolled in the Veterans Affairs Rheumatoid Arthritis (VARA) registry ... Read more >>

J Rheumatol (The Journal of rheumatology)
[2021, 48(6):813-820]

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Intramuscular Fat Influences Neuromuscular Activation of the Gluteus Medius in Older Adults.

Marcel B Lanza, Alice S Ryan, Vicki Gray, William J Perez, Odessa Addison,

The amount of tissue between the muscle and surface electromyography (sEMG) electrode influences the sEMG signals. Increased intramuscular adipose tissue (IMAT) of the hip abductor muscles negatively impacts balance in older individuals, but it is unknown if this is related to the ability to activate the muscles. The aim of ... Read more >>

Front Physiol (Frontiers in physiology)
[2020, 11:614415]

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Association between disease progression and depression onset in persons with radiographic knee osteoarthritis.

Alan M Rathbun, Michelle D Shardell, Alice S Ryan, Michelle S Yau, Joseph J Gallo, Megan S Schuler, Elizabeth A Stuart, Marc C Hochberg,

<h4>Objectives</h4>Osteoarthritis (OA) disease progression may lead to deteriorating psychosocial function, but it is unclear what aspects of disease severity are related to the onset of depression. This study assessed which components of OA disease progression cumulatively contribute to depression onset in persons with radiographic knee OA.<h4>Methods</h4>Osteoarthritis Initiative participants (n = 1651) with ... Read more >>

Rheumatology (Oxford) (Rheumatology (Oxford, England))
[2020, 59(11):3390-3399]

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Kinetic, muscle structure, and neuromuscular determinants of weight transfer phase prior to a lateral choice reaction step in older adults.

Marcel B Lanza, Odessa Addison, Alice S Ryan, William J Perez, Vicki Gray,

The present study aimed to investigate the association between rate of torque development (RTD), rate of activation (RoA), and muscle structure [muscle cross-sectional area (CSA), intramuscular fat (IMAT) and high density lean muscle (HDL)] with the weight transfer phase (WTP) during a choice reaction step test (CST) in older adults. ... Read more >>

J Electromyogr Kinesiol (Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology)
[2020, 55:102484]

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Neuromuscular Electrical Stimulation and High-Protein Supplementation After Subarachnoid Hemorrhage: A Single-Center Phase 2 Randomized Clinical Trial.

Neeraj Badjatia, Stephanie Sanchez, Gabriella Judd, Rachel Hausladen, David Hering, Melissa Motta, Gunjan Parikh, Wendy Chang, Nicholas Morris, J Marc Simard, John Sorkin, George F Wittenberg, Alice S Ryan,

<h4>Introduction</h4>Aneurysmal subarachnoid hemorrhage (SAH) survivors live with long-term residual physical and cognitive disability. We studied whether neuromuscular electrical stimulation (NMES) and high-protein supplementation (HPRO) in the first 2 weeks after SAH could preserve neuromotor and cognitive function as compared to standard of care (SOC) for nutrition and mobilization.<h4>Methods</h4>SAH subjects with ... Read more >>

Neurocrit Care (Neurocritical care)
[2021, 35(1):46-55]

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Evaluation of amikacin use and comparison of the models implemented in two Bayesian forecasting software packages to guide dosing.

Alice C Ryan, Jane E Carland, Robert C McLeay, Cindy Lau, Deborah J E Marriott, Richard O Day, Sophie L Stocker,

<h4>Aims</h4>Bayesian forecasting software can assist in guiding therapeutic drug monitoring (TDM)-based dose adjustments for amikacin to achieve therapeutic targets. This study aimed to evaluate amikacin prescribing and TDM practices, and to determine the suitability of the amikacin model incorporated into the DoseMeRx® software as a replacement for the previously available ... Read more >>

Br J Clin Pharmacol (British journal of clinical pharmacology)
[2021, 87(3):1422-1431]

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Feasibility and effects of high-intensity interval training in older adults living with HIV.

Brandon C Briggs, Alice S Ryan, John D Sorkin, Krisann K Oursler,

Adults with HIV on therapy can live a normal lifespan but exhibit advanced ageing which includes reduced cardiorespiratory fitness. Our objective was to determine the feasibility and effects of high-intensity interval training (HIIT) combined with resistance training (RT) in older adults with HIV. We conducted a cross-over pilot study within ... Read more >>

J Sports Sci (Journal of sports sciences)
[2021, 39(3):304-311]

Cited: 2 times

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Effect of Icosapent Ethyl on Gynoid Fat and Bone Mineral Health in the Metabolic Syndrome: A Preliminary Report.

Michael Miller, Alice Ryan, Robert M Reed, Claire Goggins, John Sorkin, Andrew P Goldberg,

<h4>Purpose</h4>The metabolic syndrome (MetS) is a systemic disorder associated with reduced atheroprotective gynoid fat and bone mineral content (BMC). The goal of this pilot study was to assess whether administration of icosapent ethyl (IPE), a purified formulation of eicosapentaenoic acid, would maintain gynoid fat and BMC over a 9-month treatment ... Read more >>

Clin Ther (Clinical therapeutics)
[2020, 42(11):2226-2230]

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Skeletal Muscle Angiopoietin-Like Protein 4 and Glucose Metabolism in Older Adults after Exercise and Weight Loss.

Guoyan Li, Hefang Zhang, Alice S Ryan,

Angiopoietin-like protein 4 (ANGPTL4) is an adipokine that plays an important role in energy homoeostasis and lipid and lipoprotein metabolism. This study was designed to determine the effect of an exercise plus weight loss intervention on ANGPTL4 expression and its relationship with metabolic health. Thirty-five obese sedentary men (<i>n</i> = ... Read more >>

Metabolites (Metabolites)
[2020, 10(9):]

Cited: 1 time

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Augmented exercise pressor response during maximal treadmill exercise is not related to systemic inflammation in stroke survivors.

Justin D Sprick, Monica C Serra, Alice S Ryan, Yunxiao Li, Jeanie Park,

<h4>Background</h4>Stroke survivors have exercise intolerance that contributes to reduced quality of life and survival. While exaggerated blood pressure responses during exercise have been documented in other chronic diseases, whether stroke patients have abnormal hemodynamic responses during aerobic exercise remains unexplored.<h4>Objectives</h4>This cross-sectional study aimed to examine whether stroke survivors have exaggerated ... Read more >>

Top Stroke Rehabil (Topics in stroke rehabilitation)
[2021, 28(4):251-257]

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Role of Skeletal Muscle Mitochondrial Dysfunction in CKD.

Alice S Ryan,

Clin J Am Soc Nephrol (Clinical journal of the American Society of Nephrology : CJASN)
[2020, 15(7):912-913]

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FoodFoto: A Systems Thinking Approach to Dietary Intake Collection, Storage and Analysis.

Mary Regan, Seon-Yoon Chung, Tonia Sofoluke, Zahra Rahmaty, G Man Zhang, Tracy Zvenyach, Alice S Ryan, Carla L Storr, Mary Johantgen, Colin Hunter,

Comput Inform Nurs (Computers, informatics, nursing : CIN)
[2020, 38(6):265-272]

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Depression Subtypes in Individuals With or at Risk for Symptomatic Knee Osteoarthritis.

Alan M Rathbun, Megan S Schuler, Elizabeth A Stuart, Michelle D Shardell, Michelle S Yau, Joseph J Gallo, Alice S Ryan, Marc C Hochberg,

<h4>Objective</h4>The present study was undertaken to identify depression subtypes in individuals with or at risk for symptomatic knee osteoarthritis (OA) and to evaluate differences in pain and disability trajectories between groups.<h4>Methods</h4>Participants (n = 4,486) were enrolled in the Osteoarthritis Initiative. Latent class analysis was applied to the 20-item Center for ... Read more >>

Arthritis Care Res (Hoboken) (Arthritis care & research)
[2020, 72(5):669-678]

Cited: 4 times

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Dietary and Serum Omega-6/Omega-3 Fatty Acids Are Associated with Physical and Metabolic Function in Stroke Survivors.

Monica C Serra, Alice S Ryan, Charlene E Hafer-Macko, Manuel Yepes, Fadi B Nahab, Thomas R Ziegler,

The purpose of this study was to quantify habitual dietary and systemic omega-6 and omega-3 fatty acids and their ratios and to determine their relationship with physical and metabolic function in a cohort of chronic adult stroke survivors. Twenty-five older chronic stroke survivors (age: 63 ± 8 years; BMI: 31 ... Read more >>

Nutrients (Nutrients)
[2020, 12(3):]

Cited: 1 time

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Dietary Quality Among Older Overweight or Obese Veterans With Dysmobility

Elizabeth Parker, Lauren Bergamo, Will Perez, Leslie Katzel, Alice Ryan, Steven Prior, Monica Serra, Odessa Addison,

Abstract Older adults have unique dietary challenges due to a myriad of factors including age-related taste and smell changes and lack of nutrition knowledge that increase the risk for poor dietary quality. Healthier dietary quality is associated with higher muscle mass, strength and physical performance which may reduce the development ... Read more >>

Innov Aging (Innovation in aging)
[2020, 4(Suppl 1):230-230]

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Age-Dependent Changes in Nuclear Mechanotransduction as a Driver of Sarcopenia

Shama Iyer, Christopher Ward, Joseph Stains, Alice Ryan, Eric Folker, Richard Lovering,

Abstract Informed by evidence that dysregulated nuclear dynamics and nuclear transport may contribute to atrophy in diseased skeletal muscle, the purpose of this study was to assess nuclear deformability, permeability, transport, and mechano-signaling outputs (YAP/TAZ, a marker of mechano-responsiveness, and their downstream genes) in aging skeletal muscle. We hypothesized that ... Read more >>

Innov Aging (Innovation in aging)
[2020, 4(Suppl 1):129-129]

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