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Author Alexandre De la Taille

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Urology surgical activity and COVID-19: risk assessment at the epidemic peak: a Parisian multicentre experience.

Alexandre Ingels, Steeven Bibas, Maher Abdessater, Thomas Tabourin, Morgan Roupret, Emmanuel Chartier-Kastler, Gwendolyn Barker, Nouha Tobbal, Steeve Doizi, Olivier Cussenot, Doriane Prost, Francois Desgrandchamps, Idir Ouzaid, Paul Rollin, Jean-Francois Hermieu, Francois Audenet, Mickael Userovici, Arnaud Mejean, Julien Anract, Sabine Roux, Michael Peyromaure, Nicolas Couteau, Cédric Lebacle, Jacques Irani, Dimitri Vordos, René Yiou, Andras Hoznek, Cecile M Champy, Jose Batista Da Costa, Alexandre de la Taille,

BJU Int (BJU international)
[2020, 126(4):436-440]

Cited: 3 times

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Restaging the Biochemical Recurrence of Prostate Cancer with [68Ga]Ga-PSMA-11 PET/CT: Diagnostic Performance and Impact on Patient Disease Management.

Aloÿse Fourquet, Lucien Lahmi, Timofei Rusu, Yazid Belkacemi, Gilles Créhange, Alexandre de la Taille, Georges Fournier, Olivier Cussenot, Mathieu Gauthé,

<h4>Background</h4>Detection rates of [<sup>68</sup>Ga]Ga-PSMA-11 PET/CT on the restaging of prostate cancer (PCa) patients presenting with biochemical recurrence (BCR) have been well documented, but its performance and impact on patient management have not been evaluated as extensively.<h4>Methods</h4>Retrospective analysis of PCa patients presenting with BCR and referred for [<sup>68</sup>Ga]Ga-PSMA-11 PET/CT. Pathological foci ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(7):]

Cited: 0 times

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Comorbidity and frailty assessment in renal cell carcinoma patients.

Jean Courcier, Alexandre De La Taille, Nathalie Lassau, Alexandre Ingels,

<h4>Purpose</h4>Renal cell carcinoma (RCC) incidence has considerably increased during the last decades without any real impact on age-standardized mortality. It questions the relevance of aggressive treatments carrying potential side effects. Conservative management should be considered for frail patients. Comorbidity and frailty assessment in RCC patients is paramount before engaging a ... Read more >>

World J Urol (World journal of urology)
[2021, :]

Cited: 0 times

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Neoadjuvant treatment with androgen receptor signaling inhibitors prior to radical prostatectomy: a systematic review.

Gaëtan Devos, Bram Vansevenant, Gert De Meerleer, Andries Clinckaert, Wout Devlies, Frank Claessens, Markus Graefen, Thomas Steuber, Alberto Briganti, Alexandre de la Taille, Hendrik Van Poppel, Steven Joniau,

<h4>Context</h4>There is an urgent need to develop novel treatment strategies in patients with unfavorable intermediate- and high-risk localized prostate cancer (PCa) to optimize the outcome of these patients. Androgen receptor signaling inhibitors (ARSI) have demonstrated a survival benefit in metastatic hormonesensitive and castration-resistant PCa. A similar benefit might be expected ... Read more >>

World J Urol (World journal of urology)
[2021, :]

Cited: 0 times

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Impact of the COVID-19 pandemic on oncological and functional robotic-assisted surgical procedures.

Thomas Blanc, Ugo Pinar, Julien Anract, Jalal Assouad, François Audenet, Bruno Borghese, Alexandre De La Taille, Alaa El Ghoneimi, Pierre Mongiat-Artus, Pierre Mordant, Christophe Penna, Morgan Roupret,

The COVID-19 pandemic led to a decrease in surgical activity to avoid nosocomial contamination. Robotic-assisted surgery safety is uncertain, since viral dissemination could be facilitated by gas environment. We assessed the impact and safety of the COVID-19 pandemic on robotic-assisted surgery. Data were collected prospectively during lockdown (March 16th-April 30th ... Read more >>

J Robot Surg (Journal of robotic surgery)
[2021, :]

Cited: 0 times

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A comparison of perioperative outcomes of laparoscopic versus open nephroureterectomy for upper tract urothelial carcinoma: a propensity score matching analysis.

Luca Afferi, Mohammad Abufaraj, Francesco Soria, David D'Andrea, Evanguelos Xylinas, Thomas Seisen, Morgan Roupret, Chiara Lonati, Alexandre De la Taille, Benoit Peyronnet, Ekaterina Laukhtina, Benjamin Pradere, Andrea Mari, Wojciech Krajewski, Mario Alvarez-Maestro, Eiji Kikuchi, Keisuke Shigeta, Piotr Chlosta, Francesco Montorsi, Alberto Briganti, Giuseppe Simone, Paola I Ornaghi, Maria Angela Cerruto, Alessandro Antonelli, Kazumasa Matsumoto, Pierre I Karakiewicz, Livio Mordasini, Agostino Mattei, Shahrokh F Shariat, Marco Moschini,

<h4>Background</h4>Radical nephroureterectomy (RNU) with the concomitant excision of the distal ureter and bladder cuff is the current standard of care for the treatment of muscle invasive and/or high-risk upper tract urothelial carcinoma (UTUC). In small uncontrolled studies, laparoscopic RNU has been suggested to be associated with better perioperative outcomes compared ... Read more >>

Minerva Urol Nefrol (Minerva urologica e nefrologica = The Italian journal of urology and nephrology)
[2021, :]

Cited: 0 times

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Oncological outcomes of salvage radical prostatectomy for recurrent prostate cancer in the contemporary era: A multicenter retrospective study.

Giancarlo Marra, Robert Jeffrey Karnes, Giorgio Calleris, Marco Oderda, Paolo Alessio, Anna Palazzetti, Antonino Battaglia, Francesca Pisano, Stefania Munegato, Fernando Munoz, Claudia Filippini, Umberto Ricardi, Estefania Linares, Rafael Sanchez-Salas, Sanchia Goonewardene, Prokar Dasgupta, Ben Challacombe, Rick Popert, Declan Cahill, David Gillatt, Raj Persad, Juan Palou, Steven Joniau, Salvatore Smelzo, Thierry Piechaud, Alexandre De La Taille, Morgan Roupret, Simone Albisinni, Roland van Velthoven, Alessandro Morlacco, Sharma Vidit, Giorgio Gandaglia, Alexander Mottrie, Joseph Smith, Shreyas Joshi, Gabriel Fiscus, Andre Berger, Monish Aron, Andre Abreu, Inderbir S Gill, Henk Van Der Poel, Derya Tilki, Declan Murphy, Nathan Lawrentschuk, John Davis, Paolo Gontero,

<h4>Background</h4>Salvage radical prostatectomy (sRP) historically yields poor functional outcomes and high complication rates. However, recent reports on robotic sRP show improved results. Our objectives were to evaluate sRP oncological outcomes and predictors of positive margins and biochemical recurrence (BCR).<h4>Methods</h4>We retrospectively collected data of sRP for recurrent prostate cancer after local ... Read more >>

Urol Oncol (Urologic oncology)
[2021, 39(5):296.e21-296.e29]

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Functional outcomes after robot-assisted pyeloplasty for ureteropelvic junction obstruction: A bi-centre experience.

Marie-Bérénice Popelin, Ugo Pinar, Daniel Benamran, Alexandre Ingels, Jérome Parra, Christophe Vaessen, Thomas Seisen, Alexandre de La Taille, Morgan Roupret,

<h4>Background</h4>Robot-assisted pyeloplasty (RALP) for patients with clinically symptomatic ureteropelvic junction obstruction (UPJO) is increasing and needs assessment.<h4>Methods</h4>Patients who underwent RALP for UPJO in two academic centres were included. Demographic and perioperative data were collected retrospectively. UPJO was evaluated by imaging pre- and post-surgery. Patients had follow-up consultations 3,6 and 12 ... Read more >>

Int J Med Robot (The international journal of medical robotics + computer assisted surgery : MRCAS)
[2021, 17(2):e2201]

Cited: 0 times

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A European Registry Evaluating Symptomatic Effectiveness of Pharmacologically Treated Patients with Lower Urinary Tract Symptoms due to Benign Prostatic Enlargement: Lessons Learned.

Andrea Tubaro, Mark Speakman, Alexandre de la Taille, Louis Martínez-Piñeiro, Richard Berges, Anup Patel, Anders Bjartell, Christien Caris, Wim Witjes,

<h4>Purpose</h4>We evaluated unmet needs of lower urinary tract symptoms-benign prostatic enlargement pharmacological treatment by measuring symptom improvement, persistence and deterioration in real life. A prospective registry was conducted for 24 months in 5 European countries and analyzed by the European Association of Urology Research Foundation.<h4>Materials and methods</h4>Previously untreated and treated ... Read more >>

J Urol (The Journal of urology)
[2021, 205(4):1145-1152]

Cited: 0 times

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Prognostic Impact of pT3 Subclassification in a Multicentre Cohort of Patients with Urothelial Carcinoma of the Renal Pelvicalyceal System Undergoing Radical Nephroureterectomy: A Propensity Score-weighted Analysis After Central Pathology Review.

Thomas Seisen, Andrea Mari, Riccardo Campi, Benoit Peyronnet, Karim Bensalah, Nathalie Rioux-Leclercq, Christian Pfister, Françoise Gobet, Alexandre De La Taille, Yves Allory, Evanguelos Xylinas, Yann Neuzillet, Camelia Radulescu, Jean-Luc Descotes, Géraldine Saada-Sebag, Jacques Irani, Céline Delpech-Debiais, Pierre Bigot, Caroline Eymerit, Sebastien Crouzet, Florence Mege-Lechevallier, Alain Ruffion, Myriam Decaussin-Petrucci, Stéphane Droupy, Pascal Roger, Xavier Durand, Philippe Camparo, Olivier Cussenot, Eva Compérat, Morgan Rouprêt,

<h4>Background</h4>The current pathological tumour-node-metastasis (pTNM) classification for upper tract urothelial carcinoma (UTUC) does not include any risk stratification of pT3 renal pelvicalyceal tumours.<h4>Objective</h4>To assess the prognostic impact of pT3 subclassification in a multicentre cohort of patients with UTUC of the renal pelvicalyceal system undergoing radical nephroureterectomy (RNU).<h4>Design, setting, and participants</h4>Data ... Read more >>

Eur Urol Focus (European urology focus)
[2020, :]

Cited: 0 times

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Preliminary assessment of patient and physician satisfaction with the use of teleconsultation in urology during the COVID-19 pandemic.

Ugo Pinar, Julien Anract, Ophélie Perrot, Thomas Tabourin, Emmanuel Chartier-Kastler, Jerome Parra, Christophe Vaessen, Alexandre de La Taille, Morgan Roupret,

<h4>Purpose</h4>Lockdown during the COVID-19 pandemic compelled urologists to change access to healthcare, especially for oncology patients. Teleconsultation is a safe way to receive medical advice without a risk of infection, and was implemented urgently in our academic centres. Our purpose was to evaluate patient and physician satisfaction with teleconsultation set ... Read more >>

World J Urol (World journal of urology)
[2021, 39(6):1991-1996]

Cited: 4 times

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Carbonic Anhydrase IX in Renal Cell Carcinoma, Implications for Disease Management.

Jean Courcier, Alexandre de la Taille, Maya Nourieh, Ingrid Leguerney, Nathalie Lassau, Alexandre Ingels,

Carbonic Anhydrase IX (CAIX) is a well-described enzyme in renal cell carcinoma, with its expression being regulated by the hypoxia-inducible factor 1 alpha, it is known for interfering with hypoxia processes. Renal carcinoma encompasses a broad spectrum of histological entities and is also described as a heterogeneous malignant tumor. Recently, ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(19):]

Cited: 0 times

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Comparison of the iliac, vaginal and umbilical graft extraction in robot-assisted laparoscopic living donor nephrectomy.

Maher Abdessater, Cécile M Champy, José Batista da Costa, Jean Courcier, René Yiou, Andras Hoznek, Dimitri Vordos, Philippe Grimbert, Marie Matignon, Tiphanie Londero, Philippe le Corvoisier, Laurent Salomon, Alexandre De la Taille, Alexandre Ingels,

<h4>Purpose</h4>To compare different extractions routes for robot-assisted living donor nephrectomy in terms of post-operative pain and renal function recovery.<h4>Methods</h4>Live donor kidney transplantation data from our institution were reviewed from November 2011 to March 2017. Postoperative pain was estimated using cumulative painkillers consumption. Variables were compared between the 3 groups with ... Read more >>

World J Urol (World journal of urology)
[2020, :]

Cited: 0 times

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Comparing oncological outcomes of laparoscopic vs open radical nephroureterectomy for the treatment of upper tract urothelial carcinoma: A propensity score-matched analysis.

Marco Moschini, Stefania Zamboni, Luca Afferi, Benjamin Pradere, Mohammad Abufaraj, Francesco Soria, David D'Andrea, Morgan Roupret, Alexandre De la Taille, Claudio Simeone, Agostino Mattei, Romain Mathieu, Karim Bensalah, Manfred Peter Wirth, Francesco Montorsi, Alberto Briganti, Andrea Gallina, Giuseppe Simone, Michele Gallucci, Carlo Di Bona, Giancarlo Marra, Andrea Mari, Ettore Di Trapani, Mario Alvarez Maestro, Wojciech Krajewski, Shahrokh F Shariat, Evanguelos Xylinas, Philipp Baumeister,

<h4>Objectives</h4>To compare oncological outcomes of open (ORNU) and laparoscopic radical nephroureterectomy (LRNU) after controlling for preoperative patient-derived factors.<h4>Patients and methods</h4>We evaluated a multi-institutional collaborative database composed of 3984 patients diagnosed with upper tract urothelial carcinoma (UTUC) treated with RNU between 2006 and 2018. To adjust for potential selection bias, propensity ... Read more >>

Arab J Urol (Arab journal of urology)
[2020, 19(1):31-36]

Cited: 1 time

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Nonmetastatic, Castration-Resistant Prostate Cancer and Survival with Darolutamide.

Karim Fizazi, Neal Shore, Teuvo L Tammela, Albertas Ulys, Egils Vjaters, Sergey Polyakov, Mindaugas Jievaltas, Murilo Luz, Boris Alekseev, Iris Kuss, Marie-Aude Le Berre, Oana Petrenciuc, Amir Snapir, Toni Sarapohja, Matthew R Smith, ,

<h4>Background</h4>Darolutamide is a structurally distinct androgen-receptor inhibitor that is approved for the treatment of nonmetastatic, castration-resistant prostate cancer. In the planned primary analysis of a phase 3 trial, the median metastasis-free survival was significantly longer with darolutamide (40.4 months) than with placebo (18.4 months). The data for the analysis of ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 383(11):1040-1049]

Cited: 15 times

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Androgenic hormones and the excess male mortality observed in COVID-19 patients: new convergent data.

Pierre-Jean Lamy, Xavier Rébillard, Francis Vacherot, Alexandre de la Taille,

World J Urol (World journal of urology)
[2020, :]

Cited: 2 times

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Re: Systematic Review of Systemic Therapies and Therapeutic Combinations with Local Treatments for High-risk Localized Prostate Cancer.

Alexandre de la Taille, Alexandre Ingels,

Eur Urol (European urology)
[2020, 78(3):472-473]

Cited: 0 times

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Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer.

Neal D Shore, Fred Saad, Michael S Cookson, Daniel J George, Daniel R Saltzstein, Ronald Tutrone, Hideyuki Akaza, Alberto Bossi, David F van Veenhuyzen, Bryan Selby, Xiaolin Fan, Vicky Kang, Jackie Walling, Bertrand Tombal, ,

<h4>Background</h4>Injectable luteinizing hormone-releasing hormone agonists (e.g., leuprolide) are the standard agents for achieving androgen deprivation for prostate cancer despite the initial testosterone surge and delay in therapeutic effect. The efficacy and safety of relugolix, an oral gonadotropin-releasing hormone antagonist, as compared with those of leuprolide are not known.<h4>Methods</h4>In this phase ... Read more >>

N Engl J Med (The New England journal of medicine)
[2020, 382(23):2187-2196]

Cited: 26 times

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A Plea for the Evaluation of the Carbon Footprint of New Mini-invasive Surgical Technologies in Urology.

Vincent Misrai, Alexandre de la Taille, Kevin C Zorn, Laurie Marrauld, Dominique Pon, Shahrokh F Shariat, Morgan Rouprêt,

Eur Urol (European urology)
[2020, 78(3):474-476]

Cited: 0 times

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Pulmonary Vein Varix Mimicking Prostate Cancer Metastasis on 68Ga-Prostate Specific Membrane Antigen-11 PET/CT.

Brian Sgard, Françoise Montravers, Aloÿse Fourquet, Alexandre de la Taille, Mathieu Gauthé,

The use of PET/CT with prostate-specific membrane antigen radioligands for staging prostate cancer patients presenting a biochemical recurrence is increasing. As a consequence, the number of reports of diagnostic pitfall of this imaging modality is also increasing. A 75-year-old man referred for a second episode of biochemical recurrence of prostate ... Read more >>

Clin Nucl Med (Clinical nuclear medicine)
[2020, 45(1):e39-e40]

Cited: 1 time

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Human CCR6+ Th17 Lymphocytes Are Highly Sensitive to Radiation-Induced Senescence and Are a Potential Target for Prevention of Radiation-Induced Toxicity.

Hoang Quy Nguyen, Yazid Belkacemi, Carl Mann, Françoise Hoffschir, Stéphane Kerbrat, Mathieu Surenaud, Patricia Zadigue, Alexandre de La Taille, Paul-Henri Romeo, Sabine Le Gouvello,

<h4>Purpose</h4>This study addresses the sensitivity of different peripheral CD4<sup>+</sup> T-lymphocyte subsets to irradiation (IR) and identifies potential targets for the prevention or treatment of radiation-induced toxicity.<h4>Methods</h4>This study was performed on peripheral blood mononuclear cells or sorted peripheral memory lymphocytes of CCR6<sup>+</sup> mucosa-homing Th17/CCR6<sup>neg</sup>Th and regulatory T subtypes of healthy volunteers. ... Read more >>

Int J Radiat Oncol Biol Phys (International journal of radiation oncology, biology, physics)
[2020, 108(1):314-325]

Cited: 3 times

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Robotic versus open radical cystectomy throughout the learning phase: insights from a real-life multicenter study.

Louis Lenfant, Riccardo Campi, Jérôme Parra, Vivien Graffeille, Alexandra Masson-Lecomte, Dimitri Vordos, Alexandre de La Taille, Mathieu Roumiguie, Marine Lesourd, Lionel Taksin, Vincent Misraï, Benjamin Granger, Guillaume Ploussard, Christophe Vaessen, Gregory Verhoest, Morgan Rouprêt,

<h4>Background and objectives</h4>Robot-assisted radical cystectomy (RARC) has been shown to be non-inferior to open radical cystectomy (ORC) for the treatment of bladder cancer (BC). However, most data on RARC come from high-volume surgeons at high-volume centers. The objective of the study was to compare perioperative and mid-term oncologic outcomes of ... Read more >>

World J Urol (World journal of urology)
[2020, 38(8):1951-1958]

Cited: 3 times

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Reference-free transcriptome exploration reveals novel RNAs for prostate cancer diagnosis.

Marina Pinskaya, Zohra Saci, Mélina Gallopin, Marc Gabriel, Ha Tn Nguyen, Virginie Firlej, Marc Descrimes, Audrey Rapinat, David Gentien, Alexandre de la Taille, Arturo Londoño-Vallejo, Yves Allory, Daniel Gautheret, Antonin Morillon,

The use of RNA-sequencing technologies held a promise of improved diagnostic tools based on comprehensive transcript sets. However, mining human transcriptome data for disease biomarkers in clinical specimens are restricted by the limited power of conventional reference-based protocols relying on unique and annotated transcripts. Here, we implemented a blind reference-free ... Read more >>

Life Sci Alliance (Life science alliance)
[2019, 2(6):]

Cited: 3 times

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Complication rate after cystectomy following pelvic radiotherapy: an international, multicenter, retrospective series of 682 cases.

Paolo Gontero, Francesca Pisano, Joan Palou, Steven Joniau, Maarten Albersen, Renzo Colombo, Alberto Briganti, Federico Pellucchi, Oscar Rodriguez Faba, Bas W van Rhijn, Elies Fransen van de Putte, Marko Babjuk, Hanz Martin Fritsche, Roman Mayr, Peter Albers, Gunter Niegisch, Julien Anract, Alexandra Masson-Lecomte, Alexandre De la Taille, Morgan Roupret, Benoit Peyronnet, Tomaso Cai, Alfred J Witjes, Max Bruins, Jack Baniel, Roy Mano, Alberto Lapini, Francesco Sessa, Jaques Irani, Maurizio Brausi, Arnulf Stenzl, Jeffrey R Karnes, Douglas Scherr, Padraic O'Malley, Benjamin Taylor, Shahrokh F Shariat, Peter Black, Hamidreza Abdi, Vsevolod B Matveev, Olga Samuseva, Dipen Parekh, Mark Gonzalgo, Malte W Vetterlein, Atiqullah Aziz, Margit Fisch, James Catto, Karl H Pang, Evanguelos Xylinas, Michael Rink, ,

<h4>Purpose</h4>Conflicting evidence exists on the complication rates after cystectomy following previous radiation (pRTC) with only a few available series. We aim to assess the complication rate of pRTC for abdominal-pelvic malignancies.<h4>Methods</h4>Patients treated with radical cystectomy following any previous history of RT and with available information on complications for a minimum ... Read more >>

World J Urol (World journal of urology)
[2020, 38(8):1959-1968]

Cited: 4 times

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How many surgically-treated angiomyolipomas are related to tuberous sclerosis complex? Insights from a retrospective multicenter study.

Cécile M Champy, Riccardo Campi, Pietro Grande, Alexandre de la Taille, Arnaud Méjean, Benjamin Granger, Marc-Olivier Bitker, Morgan Rouprêt,

<h4>Background</h4>Patients with TSC - related renal angiomyolipoma (AML) are eligible for targeted therapy with mTOR inhibitors, avoiding the morbidity of interventional management. Despite clinical criteria for TSC diagnosis have been defined, their use in routine clinical practice is likely suboptimal, leading to potential misclassification of TSC-related AML. The study aims ... Read more >>

Minerva Urol Nefrol (Minerva urologica e nefrologica = The Italian journal of urology and nephrology)
[2020, 72(2):200-206]

Cited: 0 times

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