Full Text Journal Articles by
Author Alexander Niessner

Advertisement

Find full text journal articles






Toll like receptor 2 and 9 expression on circulating neutrophils is associated with increased mortality in critically ill patients.

Max Lenz, Dominik F Draxler, Chao Zhang, Mona Kassem, Stefan P Kastl, Alexander Niessner, Kurt Huber, Johann Wojta, Gottfried Heinz, Walter S Speidl, Konstantin A Krychtiuk,

BACKGROUND:Toll-like receptors (TLRs) play an important role in inflammatory processes in critically ill patients by binding to pathogen-associated molecular patterns and danger-associated molecular patterns (DAMPs). Whether neutrophil or monocyte TLR expression patterns are associated with outcome in critical illness is unknown. OBJECTIVES:To answer this question, we conducted a prospective, observational ... Read more >>

Shock (Shock (Augusta, Ga.))
[2019, :]

Cited: 0 times

View full text PDF listing >>



2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes.

Juhani Knuuti, William Wijns, Antti Saraste, Davide Capodanno, Emanuele Barbato, Christian Funck-Brentano, Eva Prescott, Robert F Storey, Christi Deaton, Thomas Cuisset, Stefan Agewall, Kenneth Dickstein, Thor Edvardsen, Javier Escaned, Bernard J Gersh, Pavel Svitil, Martine Gilard, David Hasdai, Robert Hatala, Felix Mahfoud, Josep Masip, Claudio Muneretto, Marco Valgimigli, Stephan Achenbach, Jeroen J Bax, ,

Eur. Heart J. (European heart journal)
[2019, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Critical appraisal of the AUGUSTUS trial.

Thomas Gremmel, Patrick Sulzgruber, Alexander Niessner,

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2019, 5(4):187-188]

Cited: 0 times

View full text PDF listing >>



Bleeding and ischaemic outcomes in patients treated with dual or triple antithrombotic therapy: systematic review and meta-analysis.

Paul M Haller, Patrick Sulzgruber, Christoph Kaufmann, Bastiaan Geelhoed, Juan Tamargo, Sven Wassmann, Renate B Schnabel, Dirk Westermann, Kurt Huber, Alexander Niessner, Thomas Gremmel,

AIMS:The combination of oral anticoagulation with a P2Y12 inhibitor and aspirin in patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) is associated with a high bleeding risk. Dual antithrombotic therapy (DAT) with omission of aspirin is a promising option to reduce bleedings, but carries a yet unknown risk ... Read more >>

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2019, 5(4):226-236]

Cited: 0 times

View full text PDF listing >>



Antithrombotic Therapy and Major Adverse Limb Events in Patients With Chronic Lower Extremity Arterial Disease: Systematic Review and Meta-analysis from the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy in Collaboration with the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseases.

Gianluigi Savarese, Martin F Reiner, Alicia Uijl, Domenico D Amario, Stefan Agewall, Dan Atar, Iris Baumgartner, Claudio Borghi, Marco De Carlo, Heinz Drexel, Juan Carlos Kaski, Keld P Kjeldsen, Nils Kucher, Lars H Lund, Alexander Niessner, Anne Grete Semb, Thomas A Schmidt, Patrick Sulzgruber, Juan Tamargo, Cristiana Vitale, Sven Wassmann, Victor Aboyans, Basil S Lewis,

INTRODUCTION:The role and selection of antithrombotic therapy to improve limb outcomes in chronic lower extremity artery disease (LEAD) is still debated. We conducted a meta-analysis to examine the efficacy and safety of anti-thrombotic and more intense antithrombotic therapy on limb outcomes and limb salvage in patients with chronic LEAD. METHODS:Study ... Read more >>

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2019, :]

Cited: 0 times

View full text PDF listing >>



Discriminatory power of scoring systems for outcome prediction in patients with extracorporeal membrane oxygenation following cardiovascular surgery†.

Lore Schrutka, Felix Rohmann, Christina Binder, Thomas Haberl, Ben Dreyfuss, Gottfried Heinz, Irene M Lang, Alessia Felli, Barbara Steinlechner, Alexander Niessner, Günther Laufer, Georg Goliasch, Dominik Wiedemann, Klaus Distelmaier,

OBJECTIVES:Although extracorporeal membrane oxygenation (ECMO) represents a rapidly evolving treatment option in patients with refractory heart or lung failure, survival remains poor and appropriate risk stratification challenging because established risk prediction models have not been validated for this specific population. METHODS:This observational single-centre registry included a total of 240 patients ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2019, 56(3):534-540]

Cited: 1 time

View full text PDF listing >>



Oral Anticoagulation in patients with non-valvular atrial fibrillation and a CHA2DS2-VASc score of 1.

Patrick Sulzgruber, Sven Wassmann, Anne Grete Semb, Wolfram Doehner, Petr Widimsky, Thomas Gremmel, Juan Carlos Kaski, Gianluigi Savarese, Giuseppe M C Rosano, Claudio Borghi, Keld Kjeldsen, Christian Torp-Pedersen, Thomas Andersen Schmidt, Basil S Lewis, Heinz Drexel, Juan Tamargo, Dan Atar, Stefan Agewall, Alexander Niessner,

Eur. Heart J. (European heart journal)
[2019, 40(36):3010-3012]

Cited: 0 times

View full text PDF listing >>



Response to: Current opinion of the ESC Working Group on Cardiovascular Pharmacotherapy and ESC Council on Stroke.

Patrick Sulzgruber, Alexander Niessner,

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2019, :]

Cited: 0 times

View full text PDF listing >>



The age of RCT`s 3 Important Aspects of RCT`s in Cardiovascular Pharmacotherapy with examples from Lipid and Diabetes Trials.

Heinz Drexel, Giuseppe M C Rosano, Basil S Lewis, Kurt Huber, Alexander Vonbank, Jörn F Dopheide, Arthur Mader, Alexander Niessner, Gianluigi Savarese, Sven Wassmann, Stefan Agewall,

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2019, :]

Cited: 0 times

View full text PDF listing >>



Lipid management in rheumatoid arthritis: a position paper by the Cardiovascular Pharmacotherapy Working Group of European Society of Cardiology.

Ivana Hollan, Nicoletta Ronda, Patrick Dessein, Stefan Agewall, George Karpouzas, Juan Tamargo, Alexander Niessner, Gianluigi Savarese, Giuseppe Rosano, Juan Carlos Kaski, Sven Wassmann, Pier Luigi Meroni,

Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity, partly due to alterations in lipoprotein quantity, quality and cell cholesterol trafficking. Although cardiovascular disease significantly contributes to mortality excess in RA, cardiovascular prevention has been largely insufficient. Because of limited evidence, optimal strategies for lipid management (LM) in RA have ... Read more >>

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2019, :]

Cited: 0 times

View full text PDF listing >>



Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

Sonia Shah, Albert Henry, Carolina Roselli, Honghuang Lin, Garðar Sveinbjörnsson, Ghazaleh Fatemifar, Åsa Hedman, Jemma Wilk, Michael Morley, Mark Chaffin, Anna Helgadottir, Niek Verweij, Abbas Dehghan, Peter Almgren, Charlotte Andersson, Krishna Aragam, Johan Ärnlöv, Joshua Backman, Mary Biggs, Heather Bloom, Jeffrey Brandimarto, Michael Brown, Leonard Buckbinder, David Carey, Daniel Chasman, Xing Chen, Xu Chen, Jonathan Chung, William Chutkow, James Cook, Graciela Delgado, Spiros Denaxas, Alexander Doney, Marcus Dörr, Samuel Dudley, Michael Dunn, Gunnar Engström, Tõnu Esko, Stephan Felix, Chris Finan, Ian Ford, Mohsen Ghanbari, Sahar Ghasemi, Vilmantas Giedraitis, Franco Giulianini, John Gottdiener, Stefan Gross, Daníel Guðbjartsson, Rebecca Gutmann, Christopher Haggerty, Pim van der Harst, Craig Hyde, Erik Ingelsson, Wouter Jukema, Maryam Kavousi, Kay-Tee Khaw, Marcus Kleber, Lars Køber, Andrea Koekemoer, Claudia Langenberg, Lars Lind, Cecilia Lindgren, Barry London, Luca Lotta, Ruth Lovering, Jian’an Luan, Patrik Magnusson, Anubha Mahajan, Kenneth Margulies, Winfried März, Olle Melander, Ify Mordi, Thomas Morgan, Andrew Morris, Andrew Morris, Alanna Morrison, Michael Nagle, Christopher Nelson, Alexander Niessner, Teemu Niiranen, Michelle O’Donoghue, Anjali Owens, Colin Palmer, Helen Parry, Markus Perola, Eliana Portilla-Fernandez, Bruce Psaty, Kenneth Rice, Paul Ridker, Simon Romaine, Jerome Rotter, Perttu Salo, Veikko Salomaa, Jessica van Setten, Alaa Shalaby, Diane Smelser, Nicholas Smith, Steen Stender, David Stott, Per Svensson, Mari-Liis Tammesoo, Kent Taylor, Maris Teder-Laving, Alexander Teumer, Guðmundur Thorgeirsson, Unnur Thorsteinsdottir, Christian Torp-Pedersen, Stella Trompet, Benoit Tyl, Andre Uitterlinden, Abirami Veluchamy, Uwe Völker, Adriaan Voors, Xiaosong Wang, Nicholas Wareham, Dawn Waterworth, Peter Weeke, Raul Weiss, Kerri Wiggins, Heming Xing, Laura Yerges-Armstrong, Bing Yu, Faiez Zannad, Jing Hua Zhao, Harry Hemingway, Nilesh Samani, John J.V. McMurray, Jian Yang, Peter Visscher, Christopher Newton-Cheh, Anders Malarstig, Hilma Holm, Steven Lubitz, Naveed Sattar, Michael Holmes, Thomas Cappola, Folkert Asselbergs, Aroon Hingorani, Karoline Kuchenbaecker, Patrick Ellinor, Chim Lang, Kari Stefansson, Gustav Smith, Ramachandran Vasan, Daniel Swerdlow, Thomas Lumbers, , , ,

Abstract Heart failure (HF) is a leading cause of morbidity and mortality worldwide 1 . A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving the observed heritability of HF largely unexplained 2–4 . We report the ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Oral anticoagulation in patients with non-valvular atrial fibrillation and a CHA2DS2-VASc score of 1: a current opinion of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy and European Society of Cardiology Council on Stroke.

Patrick Sulzgruber, Sven Wassmann, Anne Grete Semb, Wolfram Doehner, Petr Widimsky, Thomas Gremmel, Juan Carlos Kaski, Gianluigi Savarese, Giuseppe M C Rosano, Claudio Borghi, Keld Kjeldsen, Christian Torp-Pedersen, Thomas Andersen Schmidt, Basil S Lewis, Heinz Drexel, Juan Tamargo, Dan Atar, Stefan Agewall, Alexander Niessner,

Oral anticoagulation in patients presenting with non-valvular atrial fibrillation and a CHA2DS2-VASc score of 1 (CHA2DS2-VASc of 2 in women) remains a challenging approach in clinical practice. Therapeutic decisions need to balance the individual benefit of reducing thromboembolic risk against the potential harm due to an increase in bleeding risk ... Read more >>

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2019, 5(3):171-180]

Cited: 0 times

View full text PDF listing >>



Correction to: Non-vitamin K antagonist oral anticoagulants in patients with an increased risk of bleeding.

Thomas Gremmel, Alexander Niessner, Hans Domanovits, Martin Frossard, Gürkan Sengölge, Barbara Steinlechner, Thomas Sycha, Michael Wolzt, Ingrid Pabinger,

Correction to: Wien Klin Wochenschr 2018 https://doi.org/10.1007/s00508-018-1381-5 Unfortunately, the original version of this article contained two mistakes.The text passage "It should be mentioned here that in the case of apixaban, dose adjustment is not based on GFR. A lower dosage of apixaban …. ... Read more >>

Wien. Klin. Wochenschr. (Wiener klinische Wochenschrift)
[2019, 131(5-6):135]

Cited: 0 times

View full text PDF listing >>



Aortic stenosis is an independent predictor for outcome in patients with in-hospital cardiac arrest.

Patrick Sulzgruber, Sebastian Schnaubelt, Marco Pesce, Thomas Uray, Jan Niederdöckl, Hans Domanovits, Raphael Rosenhek, Thomas Binder, Klaus Distelmaier, Christian Hengstenberg, Alexander Niessner, Georg Goliasch,

BACKGROUND:Prognostic tools for decision-making whether to continue advanced life support or limit life sustaining interventions in In-Hospital Cardiac Arrest (IHCA), remain scarce and inconclusive. In this regard it seems intuitive that the presence of aortic stenosis (AS) impacts on both central and peripheral perfusion during resuscitative attempts and might worsen ... Read more >>

Resuscitation (Resuscitation)
[2019, 137:156-160]

Cited: 0 times

View full text PDF listing >>



De-Ritis Ratio Improves Long-Term Risk Prediction after Acute Myocardial Infarction.

Matthias Steininger, Max-Paul Winter, Thomas Reiberger, Lorenz Koller, Feras El-Hamid, Stefan Forster, Sebastian Schnaubelt, Christian Hengstenberg, Klaus Distelmaier, Georg Goliasch, Johann Wojta, Aurel Toma, Alexander Niessner, Patrick Sulzgruber,

BACKGROUND:Recent evidence suggested levels of aspartate aminotransferase (AST), alanine transaminase (ALT), and AST/ALT ratio (De-Ritis ratio) were associated with a worse outcome after acute myocardial infarction (AMI). However, their value for predicting long-term prognosis remained unknown. Therefore, we investigated the prognostic potential of transaminases on patient outcome after AMI from ... Read more >>

J Clin Med (Journal of clinical medicine)
[2018, 7(12):]

Cited: 1 time

View full text PDF listing >>



Reasons for disparity in statin adherence rates between clinical trials and real-world observations: a review.

Alexander Vonbank, Heinz Drexel, Stefan Agewall, Basil S Lewis, Joern F Dopheide, Keld Kjeldsen, Claudio Ceconi, Gianluigi Savarese, Giuseppe Rosano, Sven Wassmann, Alexander Niessner, Thomas Andersen Schmidt, Christoph H Saely, Iris Baumgartner, Juan Tamargo,

With statins, the reported rate of adverse events differs widely between randomized clinical trials (RCTs) and observations in clinical practice, the rates being 1-2% in RCTs vs. 10-20% in the so-called real world. One possible explanation is the claim that RCTs mostly use a run-in period with a statin. This ... Read more >>

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2018, 4(4):230-236]

Cited: 3 times

View full text PDF listing >>



Critical appraisal of the COMPASS trial.

Alexander Niessner, Stefan Agewall,

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2018, 4(4):191-192]

Cited: 0 times

View full text PDF listing >>



Non-vitamin K antagonist oral anticoagulants in patients with an increased risk of bleeding.

Thomas Gremmel, Alexander Niessner, Hans Domanovits, Martin Frossard, Gürkan Sengölge, Barbara Steinlechner, Thomas Sycha, Michael Wolzt, Ingrid Pabinger,

The non-vitamin K antagonist oral anticoagulants (NOACs) have considerably changed clinical practice and are increasingly being used as an alternative to vitamin K antagonists (VKAs) for 3 main reasons: 1) an improved benefit-risk ratio (in particular lower rates of intracranial bleeding), 2) a more predictable effect without the need for routine monitoring, and 3) fewer food and ... Read more >>

Wien. Klin. Wochenschr. (Wiener klinische Wochenschrift)
[2018, 130(23-24):722-734]

Cited: 0 times

View full text PDF listing >>



Blood urea nitrogen has additive value beyond estimated glomerular filtration rate for prediction of long-term mortality in patients with acute myocardial infarction.

Bernhard Richter, Patrick Sulzgruber, Lorenz Koller, Matthias Steininger, Feras El-Hamid, David J Rothgerber, Stefan Forster, Georg Goliasch, Benjamin I Silbert, Elias L Meyer, Christian Hengstenberg, Johann Wojta, Alexander Niessner,

OBJECTIVES:Blood urea nitrogen (BUN) has been shown to independently predict short- and intermediate-term outcomes in patients with acute myocardial infarction (AMI). We aimed to assess the additive predictive value of BUN beyond estimated glomerular filtration rate (eGFR) in AMI patients with an 8.6-year follow-up. METHODS:This retrospective, observational single-centre study included ... Read more >>

Eur. J. Intern. Med. (European journal of internal medicine)
[2019, 59:84-90]

Cited: 0 times

View full text PDF listing >>



Research update for articles published in EJCI in 2016.

Christopher Adlbrecht, Alejandro Blanco-Verea, María C Bouzas-Mosquera, María Brion, Martin Burtscher, Federico Carbone, Ting-Ting Chang, Evangelia Charmandari, Jaw-Wen Chen, Liane Correia-Costa, Robin P F Dullaart, Makarios Eleftheriades, Beatriz Fernandez-Fernandez, Georg Goliasch, Thomas Gremmel, Menno Evert Groeneveld, Alexandrino Henrique, Martin Huelsmann, Christian Jung, Michael Lichtenauer, Fabrizio Montecucco, Nicolas C Nicolaides, Alexander Niessner, Carlos Palmeira, Markus Pirklbauer, Maria Dolores Sanchez-Niño, Alexandros Sotiriadis, Teresa Sousa, Patrick Sulzgruber, André P van Beek, Nicola Veronese, Max-Paul Winter, Kak Khee Yeung, Alberto Bouzas-Mosquera,

Eur. J. Clin. Invest. (European journal of clinical investigation)
[2018, 48(10):e13016]

Cited: 0 times

View full text PDF listing >>



The "Pectoral-Gap Phenomenon": A Hypothesis on Origin and Mechanism.

Sebastian Schnaubelt, Georgios Neophytou, Bernhard Richter, Hans Domanovits, Alexander Niessner, Patrick Sulzgruber,

Sports Med (Sports medicine (Auckland, N.Z.))
[2018, 48(8):1987-1988]

Cited: 0 times

View full text PDF listing >>



Oxygenation in post-resuscitation care-how much is too much?

Sebastian Schnaubelt, Hans Domanovits, Alexander Niessner, Patrick Sulzgruber,

J Thorac Dis (Journal of thoracic disease)
[2018, 10(Suppl 18):S2111-S2113]

Cited: 0 times

View full text PDF listing >>



Expert consensus document on the management of hyperkalaemia in patients with cardiovascular disease treated with renin angiotensin aldosterone system inhibitors: coordinated by the Working Group on Cardiovascular Pharmacotherapy of the European Society of Cardiology.

Giuseppe M C Rosano, Juan Tamargo, Keld P Kjeldsen, Mitja Lainscak, Stefan Agewall, Stefan D Anker, Claudio Ceconi, Andrew J S Coats, Heinz Drexel, Gerasimos Filippatos, Juan Carlos Kaski, Lars Lund, Alexander Niessner, Piotr Ponikowski, Gianluigi Savarese, Thomas A Schmidt, Petar Seferovic, Sven Wassmann, Thomas Walther, Basil S Lewis,

Renin angiotensin aldosterone system inhibitors/antagonists/blockers (RAASi) are a cornerstone in treatment of patients with cardiovascular diseases especially in those with heart failure (HF) due to their proven effect on surrogate and hard endpoints. Renin angiotensin aldosterone system inhibitors are also the basis in treatment of arterial hypertension, and they are ... Read more >>

Eur Heart J Cardiovasc Pharmacother (European heart journal. Cardiovascular pharmacotherapy)
[2018, 4(3):180-188]

Cited: 4 times

View full text PDF listing >>



Cardiac arrest as an age-dependent prognosticator for long-term mortality after acute myocardial infarction: the potential impact of infarction size.

Patrick Sulzgruber, Sebastian Schnaubelt, Lorenz Koller, Georg Goliasch, Jan Niederdöckl, Alexander Simon, Feras El-Hamid, David-Jonas Rothgerber, Johann Wojta, Alexander Niessner,

BACKGROUND::The development of cardiac arrhythmias resulting in cardiac arrest represents a severe complication in patients with acute myocardial infarction. While the worsening of the prognosis in this vulnerable patient collective is well known, less attention has been paid to its age-specific relevance from a long-term perspective. METHODS::Based on a clinical ... Read more >>

Eur Heart J Acute Cardiovasc Care (European heart journal. Acute cardiovascular care)
[2019, 8(2):153-160]

Cited: 0 times

View full text PDF listing >>



CD4+CD28null T Lymphocytes are Associated with the Development of Atrial Fibrillation after Elective Cardiac Surgery.

Patrick Sulzgruber, Barbara Thaler, Lorenz Koller, Johanna Baumgartner, Arnold Pilz, Matthias Steininger, Sebastian Schnaubelt, Tatjana Fleck, Günther Laufer, Barbara Steinlechner, Max-Paul Winter, Georg Goliasch, Johann Wojta, Alexander Niessner,

Post-operative atrial fibrillation (POAF) is postulated as a complex interaction of different pathogenic factors, suggesting inflammatory processes as a main trigger of this particular type of atrial fibrillation. Therefore, the study sought to assess the impact of cellular immunity on the development of POAF. Comparing patients developing POAF to individuals ... Read more >>

Sci Rep (Scientific reports)
[2018, 8(1):9624]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
2.9785 s