Full Text Journal Articles by
Author Alexander Muacevic

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Virtual Residency Interviews: Optimization for Applicants

Alexander Muacevic, John R Adler, Benjamin A Sarac, Kevin Calamari, Jeffrey Janis,

Social distancing guidelines during the coronavirus disease 2019 (COVID-19) pandemic have created substantial changes in undergraduate medical education in the United States. Specifically, the Coalition for Physician Accountability recommended that all programs transition to online interviews and visits for the 2020-21 application cycle. Current literature lacks concrete recommendations with visual examples for ... Read more >>

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Laparoscopic Resection of a Gastric Diverticulum in an Adolescent

Alexander Muacevic, John R Adler, Jerry French, Arthur Meyers, Jennifer Mills, William Adamson, Tamarah Westmoreland,

Gastric diverticula rarely occur in adolescence. In adults, they are predominantly congenital, asymptomatic, and are located adjacent to the gastroesophageal junction on the posterior aspect of the stomach wall. In this report we present a 14-year-old female who underwent laparoscopic gastric diverticulectomy after incidental discovery on magnetic resonance urography. ... Read more >>

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Subacute Massive Pulmonary Embolism Treated With Streptokinase

Alexander Muacevic, John R Adler, Naisargee N Solanki, Narendra Tanwar, Nilesh D Solanki,

Subacute massive pulmonary embolism occurs insidiously over weeks, has a high mortality rate, and may be less amenable to systemic thrombolysis. It is associated with a high likelihood of the development of pulmonary hypertension. The subacute presentation makes it difficult to diagnose leading to treatment delays and poor clinical outcomes. ... Read more >>

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Perichondritis: Not All Ear Pain Is Otitis

Alexander Muacevic, John R Adler, Mark D Rivera-Morales, Jennifer L Rodríguez-Belén, Ariel Vera, Latha Ganti,

Acute auricular perichondritis is an infection and inflammatory disease of the external ear that can potentially cause serious complications if not diagnosed and treated promptly. Delays in treatment can lead to devastating focal cartilage necrosis and, subsequently, permanent deformities of the ear. We present the case of a two-year-old boy ... Read more >>

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Association Between Perioperative Hypothermia and Surgical Site Infection After Elective Abdominal Surgery: A Prospective Cohort Study

Alexander Muacevic, John R Adler, Tayyab Siddiqiui, K.M. Inam Pal, Fatima Shaukat, Hadika Mubashir, Alishah Akbar Ali, Muhammad Jehangir A Malik, Noman Shahzad,

Introduction Surgical site infections (SSIs) account for 14-16% of nosocomial infections and are one of the major causes of increased morbidity, hospital stay, cost of care, and even mortality. Hypothermia as a risk factor for SSI is debated but there is lack of conclusive evidence. The present study explores the ... Read more >>

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Implementation of Safe Sleep Practice Recommendations for Infants in Inpatient Wards

Alexander Muacevic, John R Adler, Mrouge Sobaihi, Maysaa A Banjari, Turki S Alahmadi,

Background Sudden infant death syndrome (SIDS) is defined as the sudden unexpected death of an infant, even after conducting thorough investigations and autopsy. SIDS is related to several factors, such as baby’s position and presence of pillows, blankets and objects in the crib. The implementation of safe sleep recommendations in ... Read more >>

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Endoscopic Findings in Patients With Uninvestigated Dyspepsia: A Retrospective Study From Qatar

Alexander Muacevic, John R Adler, Ahmad Badi, Vamanjore A Naushad, Nishan K Purayil, Prem Chandra, Hassan O Abuzaid, Firjith Paramba, Abdo Lutf, Mohamed Milad Abuhmaira, Abdel-Naser Y Elzouki,

Background and objective Dyspepsia is a common complaint encountered in general clinical practice. The prevalence of clinically significant endoscopy findings in dyspeptic subjects of various age groups and ethnicities in Qatar is not well studied. This study aimed to evaluate the prevalence of endoscopic findings in previously uninvestigated patients with dyspepsia. ... Read more >>

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A Curious Case of Colonic Perivascular Epithelioid Cell Tumor: A Unique Diagnosis With Variable Presentations

Alexander Muacevic, John R Adler, Joseph Bennett, Raquele Laury, Hongyan Dai, Charles Walde, Anup Kasi,

A 67-year-old female with a history of colon cancer underwent colonoscopy. An 8 mm semi-pedunculated, friable, and ulcerated lesion of the ascending colon was removed completely using a hot snare. Immunohistochemical staining showed strong positivity for transcription factor binding to IGHM enhancer 3 (TFE-3) and was partially positive for Human ... Read more >>

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Postcholecystectomy Duodenal Injury: Role of Conservative Management

Alexander Muacevic, John R Adler, Subhash Soni, Ashish Swami, Taruna Yadav, Kelu S Sreesanth, Vaibhav K Varshney,

Postcholecystectomy duodenal injuries are very rare complications. Early surgical intervention is a common practice due to its fatal consequences. Most of the patients with post laparoscopic cholecystectomy duodenal injury reported in literature have been successfully managed by early surgical repair. We present here a case of a 32-year-old female who ... Read more >>

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Disseminated Tuberculosis: A Case of Multiple Spread Mass

Alexander Muacevic, John R Adler, Mariana Formigo, Magda Costa, João Martins, Helena Sarmento, Jorge Cotter,

Disseminated tuberculosis is associated with significant morbidity and mortality. It results from a lymphohematogenous dissemination of mycobacterium tuberculosis (MT) and its atypical clinical presentation often delays the diagnosis. Diagnosis is established by identifying MT obtained from a biopsy sample in culture or acid-fast smear. Evidence suggests an initial two-month phase ... Read more >>

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Chemotherapy and Immunosuppressant Therapy-Induced Posterior Reversible Encephalopathy Syndrome

Alexander Muacevic, John R Adler, Gurleen Kaur, Ibtisam Ashraf, Mercedes Maria Peck, Ruchira Maram, Alaa Mohamed, Diego Ochoa Crespo, Bilal Haider Malik,

Posterior reversible encephalopathy syndrome (PRES) is an entity which is characterized by acute to subacute onset of neurological symptoms like altered mental status, seizures, headaches and other focal neurological deficits. It is diagnosed with the help of MRI findings which typically involve the subcortical white matter of parieto-occipital lobes. In ... Read more >>

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Immediate and Short-Term Outcome of Percutaneous Atrial Septal Defects Closure in Adult Patients

Alexander Muacevic, John R Adler, Muhammad A Khan, Hussain Korejo, Arshad Sohail, Abdul S Shaikh, Najma Patel,

Background Atrial septal defect secundum (ASD II) is the commonest of the congenital heart diseases in the adult population and the closure of ASD II causes a significant improvement in hemodynamics and the clinical status of the patient. However, it carries certain risks, especially the development of post-closure pulmonary edema ... Read more >>

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A Review of Interstitial Pneumonitis Caused by Elotuzumab Through Case Discussions and Academic Writings

Alexander Muacevic, John R Adler, Ghulam Ghous, Hafiz Muhammad Hassan Shoukat, Zahid Ijaz Tarar, Muhammad Usman Zafar,

Patients with relapsed or refractory multiple myeloma have undergone two or three previous therapies are now being treated with a humanized IgG1 monoclonal antibody elotuzumab (HuLuc63) that targets F7 signalling lymphocytic activation molecule F7 (SLAMF7)- a signalling lymphocytic activation molecule. It is combined with dexamethasone and lenalidomide/pomalidomide for therapy. Adverse ... Read more >>

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Antimicrobial Resistance Patterns: Review of the Antibiogram of a Surgical Unit in a Public Tertiary Care Hospital of Pakistan

Alexander Muacevic, John R Adler, Usama Muhammad Kathia, Talha Munir, Fatima Fateh, Adeel Ahmad, Awais Amjad, Muhammad Farooq Afzal,

Introduction Antimicrobial resistance (AMR) has become a challenge in modern-day medical practice. The pace at which microbes are becoming resistant to antibiotics is greater than the discovery of novel antimicrobial agents. There is a need to study these antimicrobial patterns and, for this purpose, antibiograms should be developed at the ... Read more >>

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Safety Concerns of Nasal Corticosteroids Usage in Patients With Allergic Rhinitis

Alexander Muacevic, John R Adler, Talal A Almutairi, Abdulaziz A Aldayel, Abdulrahman S Aldayel, Fahad Alotaibi, Hamad A Alhussain,

Background Intranasal corticosteroids (INCSs) are the first-line treatment for patients with moderate to severe conditions of allergic rhinitis (AR) as per current guidelines. However, patients' knowledge and practice towards the safety of such medications remains ambiguous. Therefore, this study was undertaken to identify the awareness of and knowledge about the ... Read more >>

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Middle-Aged Man With Unstable Angina and an Inaccessible Right Coronary Artery

Alexander Muacevic, John R Adler, Kameel Kassab, Neeraj Jolly, Aviral Vij,

Acute myocardial ischemia and infarction from retrograde dissection of the aortic root into the coronary ostia is a potentially fatal condition. Unrecognized type A aortic dissection at the time of angiography for acute coronary syndrome (ACS) carries a high burden of morbidity and mortality. Cardiac computed tomography angiography (CCTA) has ... Read more >>

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Extensive Thrombosis in a Severe COVID-19 Patient Despite Prophylactic Low Molecular Weight Heparin

Alexander Muacevic, John R Adler, Sherif Elkattawy, Sahitya Posimreddy, Nirmal Guragai, Mirette Habib, Fayez Shamoon,

D-dimer >1 mcg/L has been shown to be an independent predictor of mortality, and experts from China have recommended starting prophylactic doses of anticoagulation in severe coronavirus disease 2019 (COVID-19) unless contraindicated. We present a case of extensive intravascular thrombosis in an otherwise healthy patient with severe COVID-19 disease despite ... Read more >>

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“Get Me Off This Medication!”: A Comparison Between Gastroenterology and Primary Care Regarding Patient’s Perceptions of Proton Pump Inhibitor Therapy

Alexander Muacevic, John R Adler, Raja Samir Khan, Yousaf Hadi, Swapna Gayam,

Background Not much is known about patient perceptions regarding proton pump inhibitor (PPI) de-escalation. We sought to determine the knowledge of adverse effects (AEs) and willingness to de-escalate therapy among patients presenting to primary care and subspecialty clinics. Methods We conducted an anonymous survey of patients presenting to family medicine, ... Read more >>

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Matrix Regenerating Agent (RGTA) in a Neurotrophic Corneal Ulcer

Alexander Muacevic, John R Adler, Sara Pereira, Rui Resende, Pedro Coelho, Filipa Sampaio,

Neurotrophic keratopathy is a condition associated with corneal damage and impaired corneal healing. There are no specific treatments available for this disease and current treatments are not associated with improved visual function. Matrix regenerating agents (RGTA) are recent topical agents showing positive results in the treatment of several corneal conditions, ... Read more >>

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The Difficult Clinical Decision of Thrombolytic Therapy for Submassive Pulmonary Embolism in a Community Hospital

Alexander Muacevic, John R Adler, Qian Zhang, Jonathan Vayalumkal, John Ricely, Daniel L Gray, Ahmad Raza,

Submassive or intermediate-risk pulmonary embolism (PE) occurs when an acute PE episode is associated with radiographic evidence of right heart strain without hemodynamic instability. Further risk stratification is important in determining whether systemic thrombolytic therapy should be administered when weighing the risks and benefits. It includes the risk of death ... Read more >>

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Effect of Topical Capsaicin on Painful Sensory Peripheral Neuropathy in Patients with Type 2 Diabetes: A Double-Blind Placebo-Controlled Randomised Clinical Trial

Alexander Muacevic, John R Adler, Batakeh B. Agoons, Mesmin Dehayem Yefou, Jean-Claude Katte, Martine Claude Etoa Etoga, Dayawa D Agoons, Faustin Yepnjio, Anne Boli, Yves Wasnyo, Eugene Sobngwi, Jean-Claude Mbanya,

Objective The aim of this study was to evaluate the efficacy of capsaicin in inducing significant pain relief in a population of sub-Saharan African type 2 diabetic patients with painful peripheral neuropathy. Design This was a prospective double-blind placebo-controlled randomised clinical trial. Setting A single tertiary-level hospital diabetes center in ... Read more >>

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Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depression

Alexander Muacevic, John R Adler, Prerna Sangle, Osama Sandhu, Zarmeena Aftab, Adarsh Thomas Anthony, Safeera Khan,

Depression is a common mental health condition occurring across all ages, genders, and populations and is almost always multifaceted. It can manifest as a form of metabolic disorder, endocrine disorder, cardiovascular diseases, inflammatory disorders, deficiencies, or neurodegenerative disorders. Although there have been various treatment options available for the treatment of ... Read more >>

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Proprioception After Multiligament Knee Injury: Does Ligament Repair Lead to Better Proprioceptive Acuity Than Ligament Reconstruction?

Alexander Muacevic, John R Adler, Hannah L Burton, Jon R A. Phillips, Nitin P Badhe, Benjamin J Olliverre, Christopher G Moran,

Introduction Multiligament knee injuries are uncommon but serious injuries. There is ongoing debate on the optimal treatment of these injuries. We designed a study to establish the effects of repair or reconstruction on proprioceptive outcomes following multiligament injury to the knee. Materials and Methods A total of 34 patients were ... Read more >>

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A 15-Year-Old With Tetralogy of Fallot With Pulmonic Atresia, Multiple Aorticopulmonary Collateral Arteries and Bilateral Peripheral Pulmonary Stenosis

Alexander Muacevic, John R Adler, Julia D Katz, Sivan Elkarat,

Tetralogy of Fallot (TOF) is a congenital disorder comprised of four heart defects. It is considered a critical condition that requires surgical repair. TOF may be complicated by pulmonary valve atresia (PA) and the development of major aorticopulmonary collateral arteries (MAPCA). A 15-year-old girl from Jimma, Ethiopia, was admitted to ... Read more >>

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Difficulties Encountered While Using PPE Kits and How to Overcome Them: An Indian Perspective

Alexander Muacevic, John R Adler, Ankur Agarwal, Sheetal Agarwal, Poonam Motiani,

Background After a slow start due to an effective lockdown, the coronavirus disease 2019 (COVID-19) pandemic in India has been raging at a rapid pace, posing a formidable challenge to the healthcare system in the country. The personal protective equipment (PPE) undoubtedly provides a shield of protection for the healthcare workers (HCWs) ... Read more >>

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