Full Text Journal Articles by
Author Alexander L Eastman

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PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients.

Robert V O'Toole, Deborah M Stein, Katherine P Frey, Nathan N O'Hara, Daniel O Scharfstein, Gerard P Slobogean, Tara J Taylor, Bryce E Haac, Anthony R Carlini, Theodore T Manson, Kuladeep Sudini, C Daniel Mullins, Stephen T Wegener, Reza Firoozabadi, Elliott R Haut, Michael J Bosse, Rachel B Seymour, Martha B Holden, Ida Leah Gitajn, Samuel Z Goldhaber, Alexander L Eastman, Gregory J Jurkovich, Heather A Vallier, Joshua L Gary, Conor P Kleweno, Joseph Cuschieri, Debra Marvel, Renan C Castillo, ,

<h4>Introduction</h4>Patients who sustain orthopaedic trauma are at an increased risk of venous thromboembolism (VTE), including fatal pulmonary embolism (PE). Current guidelines recommend low-molecular-weight heparin (LMWH) for VTE prophylaxis in orthopaedic trauma patients. However, emerging literature in total joint arthroplasty patients suggests the potential clinical benefits of VTE prophylaxis with aspirin. ... Read more >>

BMJ Open (BMJ open)
[2021, 11(3):e041845]

Cited: 0 times

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Removal of the Prehospital Tourniquet in the Emergency Department.

Matthew J Levy, Jason Pasley, Kyle N Remick, Alexander L Eastman, Asa M Margolis, Nelson Tang, Craig A Goolsby,

<h4>Background</h4>Life-threatening hemorrhage from extremity injuries can be effectively controlled in the prehospital environment through direct pressure, wound packing, and the use of tourniquets. Early tourniquet application has been prioritized for rapid control of severe extremity hemorrhage and is a cornerstone of prehospital trauma resuscitation guidelines. Emergency physicians must be knowledgeable ... Read more >>

J Emerg Med (The Journal of emergency medicine)
[2021, 60(1):98-102]

Cited: 0 times

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2019 Recommended Limb Tourniquets in Tactical Combat Casualty Care.

Harold R Montgomery, Rick Hammesfahr, Andrew D Fisher, Jeffrey S Cain, Dominique J Greydanus, Frank K Butler, Craig Goolsby, Alexander L Eastman,

Military and civilian trauma can be distinctly different but the leading cause of preventable trauma deaths in the prehospital environment, extremity hemorrhage, does not discriminate. The current paper is the most comprehensive review of limb tourniquets employable in the tactical combat casualty care environment and provides the first update to ... Read more >>

J Spec Oper Med (Journal of special operations medicine : a peer reviewed journal for SOF medical professionals)
[2019, 19(4):27-50]

Cited: 0 times

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A comparison of cholecystitis grading scales.

Tarik D Madni, Paul A Nakonezny, Jonathan B Imran, Luis Taveras, Holly B Cunningham, Ryan Vela, Audra T Clark, Christian T Minshall, Alexander L Eastman, Stephen Luk, Herb A Phelan, Michael W Cripps,

<h4>Background</h4>Previously, our group developed the Parkland grading scale for cholecystitis (PGS) to stratify gallbladder (GB) disease severity that can be determined immediately when performing laparoscopic cholecystectomy (LC). In prior studies, PGS demonstrated excellent interrater reliability and was internally validated as an accurate measure of LC outcomes. Here, we compare PGS ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2019, 86(3):471-478]

Cited: 0 times

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Trauma and emergency general surgery patients should be extubated with an open abdomen.

Luis R Taveras, Jonathan B Imran, Holly B Cunningham, Tarik D Madni, Roberto Taarea, Allison Tompeck, Audra T Clark, Natalie Provenzale, Folarin M Adeyemi, Christian T Minshall, Alexander L Eastman, Michael W Cripps,

<h4>Background</h4>Open abdomen (OA) and temporary abdominal closure (TAC) are common techniques to manage several surgical problems in trauma and emergency general surgery (EGS). Patients with an OA are subjected to prolonged mechanical ventilation. This can lead to increased rates of ventilator-associated pneumonia (VAP). We hypothesized that patients who were extubated ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2018, 85(6):1043-1047]

Cited: 1 time

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Inability to predict subprophylactic anti-factor Xa levels in trauma patients receiving early low-molecular-weight heparin.

Jonathan B Imran, Tarik D Madni, Audra T Clark, Paul Rizk, Emily Huang, Christian T Minshall, Luis R Taveras, Holly B Cunningham, Alexander L Eastman, Jojo P Koshy, Cory D Kacir, Michael W Cripps,

<h4>Background</h4>Standard low-molecular-weight heparin dosing may be suboptimal for venous thromboembolism prophylaxis. We aimed to identify independent predictors of subprophylactic Xa (subXa) levels in trauma patients treated under a novel early chemoprophylaxis algorithm.<h4>Methods</h4>A retrospective analysis of trauma patients from July 2016 to June 2017 who received enoxaparin 40 mg twice daily ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2018, 85(5):867-872]

Cited: 1 time

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Prospective validation of the Parkland Grading Scale for Cholecystitis.

Tarik D Madni, Paul A Nakonezny, Evan Barrios, Jonathan B Imran, Audra T Clark, Luis Taveras, Holly B Cunningham, Alana Christie, Alexander L Eastman, Christian T Minshall, Stephen Luk, Joseph P Minei, Herb A Phelan, Michael W Cripps,

<h4>Background</h4>The Parkland Grading Scale for Cholecystitis (PGS) was developed as an intraoperative grading scale to stratify gallbladder (GB) disease severity during laparoscopic cholecystectomy (LC). We aimed to prospectively validate this scale as a measure of LC outcomes.<h4>Methods</h4>Eleven surgeons took pictures of and prospectively graded the initial view of 317 GBs using ... Read more >>

Am J Surg (American journal of surgery)
[2019, 217(1):90-97]

Cited: 1 time

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Post-Mortem Evaluation of Potentially Survivable Hemorrhagic Death in a Civilian Population.

Craig Goolsby, Elizabeth Rouse, Luis Rojas, Eric Goralnick, Matthew J Levy, Thomas Kirsch, Alexander L Eastman, Arthur Kellermann, Kandra Strauss-Riggs, Nicole Hurst,

<h4>Background</h4>Although the survivability of military extremity hemorrhage is well documented, equivalent civilian data are limited. We analyzed statewide autopsy records in Maryland to determine the number of hemorrhagic deaths that might have been potentially survivable with prompt hemorrhage control. Similar analyses of battlefield deaths led to life-saving changes in military ... Read more >>

J Am Coll Surg (Journal of the American College of Surgeons)
[2018, 227(5):502-506]

Cited: 3 times

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Active-Shooter Response at a Health Care Facility.

Kenji Inaba, Alexander L Eastman, Lenworth M Jacobs, Kenneth L Mattox,

N Engl J Med (The New England journal of medicine)
[2018, 379(6):583-586]

Cited: 2 times

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Determining suicide risk in trauma patients using a universal screening program.

Jonathan B Imran, Robyn E Richmond, Tarik D Madni, Kimberly Roaten, Audra T Clark, Emily Y Huang, Ali A Mokdad, Luis R Taveras, Kareem R Abdelfattah, Michael W Cripps, Alexander L Eastman,

BACKGROUND:Trauma patients may be at elevated risk for subsequent suicide; however, it is unclear whether patients at risk can be identified during their initial presentation following injury. The objectives of this study were to evaluate the use of a standardized clinical decision support system for suicide risk screening developed by ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2018, 85(1):182-186]

Cited: 1 time

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Can CT imaging of the chest, abdomen, and pelvis identify all vertebral injuries of the thoracolumbar spine without dedicated reformatting?

Jonathan B Imran, Tarik D Madni, Jeffrey H Pruitt, Canon Cornelius, Madhu Subramanian, Audra T Clark, Ali A Mokdad, Paul Rizk, Joseph P Minei, Michael W Cripps, Alexander L Eastman,

<h4>Background</h4>The main objective of this study was to compare detection rates of clinically significant thoracolumbar spine (TLS) fracture between computed tomography (CT) imaging of the chest, abdomen, and spine (CT CAP) and CT for the thoracolumbar spine (CT TL).<h4>Methods</h4>We retrospectively identified patients at our institution with a TLS fracture over ... Read more >>

Am J Surg (American journal of surgery)
[2018, 216(1):52-55]

Cited: 1 time

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Improvised vs Commercial Tourniquets.

Matthew J Levy, Craig Goolsby, Alexander L Eastman,

JAMA (JAMA)
[2017, 318(6):575]

Cited: 1 time

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Pneumothorax.

Jonathan B Imran, Alexander L Eastman,

JAMA (JAMA)
[2017, 318(10):974]

Cited: 7 times

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The Parkland grading scale for cholecystitis.

Tarik D Madni, David E Leshikar, Christian T Minshall, Paul A Nakonezny, Canon C Cornelius, Jonathan B Imran, Audra T Clark, Brian H Williams, Alexander L Eastman, Joseph P Minei, Herb A Phelan, Michael W Cripps,

<h4>Background</h4>Gallbladders (GBs) with severe inflammation have longer operative times and an increased risk for complications. We propose a grading system using intraoperative images to better stratify GB inflammation.<h4>Methods</h4>After reviewing the intraoperative images of GBs obtained during several hundred laparoscopic cholecystectomies, we developed a five-tiered grading system based on anatomy and ... Read more >>

Am J Surg (American journal of surgery)
[2018, 215(4):625-630]

Cited: 3 times

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Cannabis Use Has Negligible Effects Following Severe Traumatic Injury.

Kareem R AbdelFattah, Courtney R Edwards, Michael W Cripps, Christian T Minshall, Herb A Phelan, Joseph P Minei, Alexander L Eastman,

Nearly half of all states have legalized medical marijuana or recreational-use marijuana. As more states move toward legalization, the effects on injured patients must be evaluated. This study sought to determine effects of cannabis positivity at the time of severe injury on hospital outcomes compared with individuals negative for illicit ... Read more >>

J Trauma Nurs (Journal of trauma nursing : the official journal of the Society of Trauma Nurses)
[2017, 24(2):141-145]

Cited: 1 time

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Evaluating Pre Burn Center Intubation Practices: An Update.

Anthony R Cai, Erica I Hodgman, Puneet B Kumar, Alvand J Sehat, Alexander L Eastman, Steven E Wolf,

A significant proportion of patients appeared to arrive at our American Burn Association-verified burn center intubated without clear benefit. The current study aims to evaluate regional prehospital intubation practices and their outcomes. All consecutive admissions from November 2012 to June 2014 were reviewed for data points associated with intubation. Demographics ... Read more >>

J Burn Care Res (Journal of burn care & research : official publication of the American Burn Association)
[2017, 38(1):e23-e29]

Cited: 2 times

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Maternal Death Due to Clostridium novyi in an Injection Drug User.

Christina Herrera, Ryan Meehan, Varsha Podduturi, Alexander L Eastman, David B Nelson,

<h4>Background</h4>Soft-tissue infections in women with subcutaneous injection drug use are often polymicrobial.<h4>Case</h4>A 21-year-old nulliparous woman presented at 14-15 weeks of gestation with several gluteal abscesses related to subcutaneous injection of heroin. She was well appearing, afebrile, and without findings of systemic illness. After empiric broad-spectrum intravenous antibiotics, same-day incision and ... Read more >>

Obstet Gynecol (Obstetrics and gynecology)
[2016, 128(4):876-879]

Cited: 3 times

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Hemorrhage control saves lives no matter the wounding pattern.

Matthew D Sztajnkrycer, Alexander L Eastman, Frank K Butler,

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2016, 81(4):806-807]

Cited: 0 times

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Improving national preparedness for intentional mass casualty events: A seamless system of evidence-based care.

Alexander L Eastman, William Fabbri, Kathryn Brinsfield, Lenworth Jacobs,

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2016, 81(5 Suppl 2 Proceedings of the 2015 Military Health Syste):S77-S80]

Cited: 0 times

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American Association for the Surgery of Trauma statement on firearm injuries.

Erik Streib, David Blake, A Britton Christmas, Keith Clancy, Christine Cocanour, Carnell Cooper, Robert P Driscoll, Alexander L Eastman, Akpofure Peter Ekeh, Richard Gonzalez, James G Hinsdale, Kimberly Joseph, Deborah A Kuhls, Scott G Thomas, Zara Cooper, ,

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2016, 80(6):849]

Cited: 4 times

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SURVIVAL MINDSET.

Alexander L Eastman, Julie Chase, Bruce J Stark,

JEMS (JEMS : a journal of emergency medical services)
[2016, 41(4):35-37]

Cited: 0 times

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The continuing threat of active shooter and intentional mass casualty events: Local law enforcement and hemorrhage control.

Alexander L Eastman,

Bull Am Coll Surg (Bulletin of the American College of Surgeons)
[2015, 100(1 Suppl):56-58]

Cited: 0 times

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A multi-institutional analysis of prehospital tourniquet use.

Rebecca Schroll, Alison Smith, Norman E McSwain, John Myers, Kristin Rocchi, Kenji Inaba, Stefano Siboni, Gary A Vercruysse, Irada Ibrahim-Zada, Jason L Sperry, Christian Martin-Gill, Jeremy W Cannon, Seth R Holland, Martin A Schreiber, Diane Lape, Alexander L Eastman, Cari S Stebbins, Paula Ferrada, Jinfeng Han, Peter Meade, Juan C Duchesne,

<h4>Background</h4>Recent military studies demonstrated an association between prehospital tourniquet use and increased survival. The benefits of this prehospital intervention in a civilian population remain unclear. The aims of our study were to evaluate tourniquet use in the civilian population and to compare outcomes to previously published military experience. We hypothesized ... Read more >>

J Trauma Acute Care Surg (The journal of trauma and acute care surgery)
[2015, 79(1):10-4; discussion 14]

Cited: 25 times

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The continuing threat of active shooter and intentional mass casualty events. Local and law enforcement and hemorrhage control.

Alexander L Eastman,

J Spec Oper Med (Journal of special operations medicine : a peer reviewed journal for SOF medical professionals)
[2015, 15(4):146-148]

Cited: 0 times

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The Hartford Consensus: THREAT, a medical disaster preparedness concept.

Lenworth M Jacobs, David S Wade, Norman E McSwain, Frank K Butler, William P Fabbri, Alexander L Eastman, Michael Rotondo, John Sinclair, Karyl J Burns,

J Am Coll Surg (Journal of the American College of Surgeons)
[2013, 217(5):947-953]

Cited: 10 times

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