Full Text Journal Articles by
Author Alexander Claus Langheinrich

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Effects of multi-deficiencies-diet on bone parameters of peripheral bone in ovariectomized mature rat.

Thaqif El Khassawna, Wolfgang Böcker, Parameswari Govindarajan, Nathalie Schliefke, Britta Hürter, Marian Kampschulte, Gudrun Schlewitz, Volker Alt, Katrin Susanne Lips, Miriam Faulenbach, Henriette Möllmann, Daniel Zahner, Lutz Dürselen, Anita Ignatius, Natali Bauer, Sabine Wenisch, Alexander Claus Langheinrich, Reinhard Schnettler, Christian Heiss,

Many postmenopausal women have vitamin D and calcium deficiency. Therefore, vitamin D and calcium supplementation is recommended for all patients with osteopenia and osteoporosis. We used an experimental rat model to test the hypothesis that induction of osteoporosis is more efficiently achieved in peripheral bone through combining ovariectomy with a ... Read more >>

PLoS One (PloS one)
[2013, 8(8):e71665]

Cited: 16 times

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In vitro evaluation of the sinus sagittalis superior thrombosis model in the rat using 3D micro- and nanocomputed tomography.

Alexander Claus Langheinrich, Mesut Yeniguen, Anne Ostendorf, Simone Marhoffer, Christian Dierkes, Susanne von Gerlach, Max Nedelmann, Marian Kampschulte, Georg Bachmann, Erwin Stolz, Tibo Gerriets,

<h4>Introduction</h4>Thrombosis of the cerebral veins and sinus are common causes of stroke. Animal models help us to understand the underlying pathophysiology of this condition. Therefore, the purpose of our study was to evaluate a well-established model for sinus sagittalis (SSS) thrombosis using micro- and nanocomputed tomography (CT) imaging.<h4>Methods</h4>SSS thrombosis was ... Read more >>

Neuroradiology (Neuroradiology)
[2010, 52(9):815-821]

Cited: 7 times

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Glomerular filtration rate measured by using triphasic helical CT with a two-point Patlak plot technique.

Nils Hackstein, Cornelia Wiegand, Wigbert Stefan Rau, Alexander Claus Langheinrich,

<h4>Purpose</h4>To determine the accuracy of the two-point Patlak plot in the calculation of glomerular filtration rate (GFR).<h4>Materials and methods</h4>Fifty patients without acute renal disorder were included. GFR was calculated by using a two-point Patlak plot technique. The computed tomography (CT) protocol consisted of a plain examination followed by two contrast ... Read more >>

Radiology (Radiology)
[2004, 230(1):221-226]

Cited: 37 times

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Effects of 3-deazaadenosine on homocysteine and atherosclerosis in apolipoprotein E-deficient mice.

Alexander Claus Langheinrich, Ruediger Christian Braun-Dullaeus, Gerhard Walker, Ina Jeide, Ralph Schilling, Kai Tammoscheit, Thomas Dreyer, Ludger Fink, Rainer Maria Bohle, Werner Haberbosch,

<h4>Objective</h4>In the past decade, elevated homocysteine concentration has achieved widespread recognition as an independent risk factor in the development of atherosclerosis. 3-Deazaadenosine (c3Ado) is a potent inhibitor and substrate for S-adenosylhomocysteine hydrolase and therefore may reduce homocysteine concentrations. The current study investigated the effect of c3Ado on serum homocysteine, atherosclerotic ... Read more >>

Atherosclerosis (Atherosclerosis)
[2003, 171(2):181-192]

Cited: 12 times

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Acute rat lung injury: feasibility of assessment with micro-CT.

Alexander Claus Langheinrich, Boris Leithäuser, Susanne Greschus, Susanne Von Gerlach, Andreas Breithecker, Fritz Reinhard Matthias, Wigbert Stephan Rau, Rainer Maria Bohle,

<h4>Purpose</h4>To evaluate the feasibility of micro-computed tomography (CT) for analysis of the lung fine structure and its alterations during endotoxin-induced lung injury.<h4>Materials and methods</h4>Intravital perfusion-fixed rat lungs with (n = 5) and without (n = 5) endotoxin perfusion were scanned with micro-CT. Three imaging modalities (conventional histology, intravital microscopy, and ... Read more >>

Radiology (Radiology)
[2004, 233(1):165-171]

Cited: 34 times

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Atherosclerotic lesions at micro CT: feasibility for analysis of coronary artery wall in autopsy specimens.

Alexander Claus Langheinrich, Rainer Maria Bohle, Susanne Greschus, Nils Hackstein, Gerhard Walker, Susanne von Gerlach, Wigbert Stephan Rau, Hans Hölschermann,

<h4>Purpose</h4>To evaluate the feasibility of micro computed tomography (CT) for analysis of the coronary artery wall.<h4>Materials and methods</h4>With micro CT, two-dimensional transverse images were generated from 10 human autopsy specimens of coronary arteries (2.5-3.5 cm long), with section thickness of 6 microm. Vessel wall perimeter, plaque area, calcified lesion area, ... Read more >>

Radiology (Radiology)
[2004, 231(3):675-681]

Cited: 47 times

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