Full Text Journal Articles by
Author Alessandro Franchi

Advertisement

Find full text journal articles






Emerging Entities and New Diagnostic Markers for Head and Neck Soft Tissue and Bone Tumors.

Alessandro Franchi, Lester D R Thompson, Juan C Hernandez-Prera, Abbas Agaimy, Michelle D Williams, Lauge H Mikkelsen, Justin A Bishop, Stefan M Willems, Henrik Hellquist, Alfio Ferlito,

Bone and soft tissue tumors of the head and neck are relatively uncommon tumors that often represent a diagnostic challenge because of the wide range of entities that must be considered in the differential diagnosis. Over the past few years, classification of bone and soft tissue tumors has evolved primarily ... Read more >>

Adv Anat Pathol (Advances in anatomic pathology)
[2021, 28(3):139-149]

Cited: 0 times

View full text PDF listing >>



High-grade Transformation/Dedifferentiation in Salivary Gland Carcinomas: Occurrence Across Subtypes and Clinical Significance.

Alena Skalova, Ilmo Leivo, Henrik Hellquist, Abbas Agaimy, Roderick H W Simpson, Göran Stenman, Vincent Vander Poorten, Justin A Bishop, Alessandro Franchi, Juan C Hernandez-Prera, David Slouka, Stefan M Willems, Kerry D Olsen, Alfio Ferlito,

High-grade transformation (HGT) or dedifferentiation has been described in a variety of salivary gland carcinomas, including acinic cell carcinoma, secretory carcinoma, adenoid cystic carcinoma, epithelial-myoepithelial carcinoma, polymorphous adenocarcinoma, low-grade mucoepidermoid carcinoma, and hyalinizing clear cell carcinoma. High-grade (HG) transformed tumors are composed of a conventional low-grade component characterized by specific ... Read more >>

Adv Anat Pathol (Advances in anatomic pathology)
[2021, 28(3):107-118]

Cited: 0 times

View full text PDF listing >>



Advertisement

Acral Dedifferentiated Chondrosarcoma: Report of a Case Arising in the Proximal Phalanx of the Fourth Finger.

Raffaele Gaeta, Giacomo Aringhieri, Virna Zampa, Antonio D'Arienzo, Lorenzo Andreani, Rodolfo Capanna, Katia Zavaglia, Alessandro Franchi,

Dedifferentiated chondrosarcoma is a well-recognized entity, but its occurrence in the distal extremities is exceedingly rare. We present the case of a 49-year-old woman who experienced local recurrence of an "enchondroma" of the proximal phalanx of the fourth finger of the left hand, which had been initially treated with intralesional ... Read more >>

Int J Surg Pathol (International journal of surgical pathology)
[2021, :10668969211010221]

Cited: 0 times

View full text PDF listing >>



Recurrent novel HMGA2-NCOR2 fusions characterize a subset of keratin-positive giant cell-rich soft tissue tumors.

Abbas Agaimy, Michael Michal, Robert Stoehr, Fulvia Ferrazzi, Pavel Fabian, Michal Michal, Alessandro Franchi, Florian Haller, Andrew L Folpe, Kemal Kösemehmetoğlu,

Giant cell tumors of soft tissue (GCT-ST) are rare low-grade neoplasms that were at one time thought to represent the soft tissue counterparts of GCT of bone (GCT-B) but are now known to lack the H3F3 mutations characteristic of osseous GCT. We present six distinctive giant cell-rich soft tissue neoplasms ... Read more >>

Mod Pathol (Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Analysis of a Preliminary microRNA Expression Signature in a Human Telangiectatic Osteogenic Sarcoma Cancer Cell Line.

Gaia Palmini, Cecilia Romagnoli, Simone Donati, Roberto Zonefrati, Gianna Galli, Francesca Marini, Teresa Iantomasi, Alessandra Aldinucci, Gigliola Leoncini, Alessandro Franchi, Giovanni Beltrami, Domenico Andrea Campanacci, Rodolfo Capanna, Maria Luisa Brandi,

Telangiectatic osteosarcoma (TOS) is an aggressive variant of osteosarcoma (OS) with distinctive radiographic, gross, microscopic features, and prognostic implications. Despite several studies on OS, we are still far from understanding the molecular mechanisms of TOS. In recent years, many studies have demonstrated not only that microRNAs (miRNAs) are involved in ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2021, 22(3):]

Cited: 0 times

View full text PDF listing >>



Distrectual osteosarcopenia in limb disuse: case report and mini literature review.

Gabriele Filoni, Michele Di Lonardo, Giovanni Mandile, Lorenzo Andreani, Francesca Falossi, Alessandro Franchi, Vanna Bottai, Rodolfo Capanna,

Osteosarcopenia is a new concept of association of osteoporosis and sarcopenia. Both of these pathologies are more frequent in old people and general affects all the skeleton with increased risk of falls and fractures, loss of global function, fragility, and mortality, but also surgical failures. The coexistence of these condition ... Read more >>

Acta Biomed (Acta bio-medica : Atenei Parmensis)
[2020, 91(14-S):e2020005]

Cited: 0 times

View full text PDF listing >>



Pleomorphic Adenoma: The Great Mimicker of Malignancy.

Juan C Hernandez-Prera, Alena Skálová, Alessandro Franchi, Alessandra Rinaldo, Vincent Vander Poorten, Peter Zbären, Alfio Ferlito, Bruce M Wenig,

Pleomorphic adenoma is the most common salivary gland neoplasm and its diagnosis is straightforward in majority of cases. However; not infrequently PA exhibits unusual and uncommon histological findings that can erroneously be confused with malignancy. The diagnostic difficulties of PA arise from its ability of mimic invasion, show atypical or ... Read more >>

Histopathology (Histopathology)
[2020, :]

Cited: 0 times

View full text PDF listing >>



[The new ReNaTuNS operating manual for nasal sinus tumor case management].

Carolina Mensi, Alessandra Binazzi, Lucia Miligi, Alessandro Franchi, Roberto Calisti, Paolo Galli, Elisa Romeo, Jana Zajacovà, Alessandro Marinaccio,

<h4>Summary</h4>No abstract available. ... Read more >>

G Ital Med Lav Ergon (Giornale italiano di medicina del lavoro ed ergonomia)
[2020, 42(4):242-243]

Cited: 0 times

View full text PDF listing >>



Papillary-cystic neoplasms of the middle ear are distinct from endolymphatic sac tumours.

Cecilia Taverna, Federica Pollastri, Rudi Pecci, Beatrice Giannoni, Caterina Fattorini, Marco Santucci, Sarina K Mueller, Robert Stoehr, Alessandro Franchi, Abbas Agaimy,

<h4>Aims</h4>Papillary neoplasms of the middle and inner ear are rare and poorly characterised. The current World Health Organization classification divides them into two major subtypes: aggressive papillary tumours (APTs) and endolymphatic sac tumours (ELSTs). The aim of this article is to present two papillary neoplasms of the middle ear that ... Read more >>

Histopathology (Histopathology)
[2020, :]

Cited: 1 time

View full text PDF listing >>



MUC4 is a valuable marker for distinguishing secretory carcinoma of the salivary glands from its mimics.

Cecilia Taverna, Martina Baněčková, Monica Lorenzon, Annarita Palomba, Alessandro Franchi, Alena Skalova, Abbas Agaimy,

<h4>Aims</h4>Secretory carcinoma (SC) (synonym: mammary analogue secretory carcinoma) is a low-grade salivary gland tumour that occurs in both major and minor salivary glands. SC is known for its wide morphological, architectural and immunohistochemical spectrum, which overlaps with those of several salivary gland neoplasms, including acinic cell carcinoma (AciCC) and intercalated ... Read more >>

Histopathology (Histopathology)
[2020, :]

Cited: 0 times

View full text PDF listing >>



A New MEN2 Syndrome with Clinical Features of Both MEN2A and MEN2B Associated with a New RET Germline Deletion.

Carlotta Giani, Teresa Ramone, Cristina Romei, Raffaele Ciampi, Alessia Tacito, Laura Valerio, Laura Agate, Clara Ugolini, Michele Marinò, Fulvio Basolo, Alessandro Franchi, Simona Borsari, Angela Michelucci, Cesare Selli, Gabriele Materazzi, Filomena Cetani, Rossella Elisei,

Background:Multiple endocrine neoplasia type 2 (MEN2) is a hereditary cancer syndrome caused by RET proto-oncogene mutation. Two different clinical variants of MEN2 are known (MEN2A and MEN2B): medullary thyroid carcinoma (MTC) almost always present and associated with pheochromocytoma (Pheo), and primary hyperparathyroidism (HPTH) in MEN2A and with Pheo and other ... Read more >>

Case Rep Endocrinol (Case reports in endocrinology)
[2020, 2020:4147097]

Cited: 0 times

View full text PDF listing >>



Synovial chondrosarcoma: a single-institution experience with molecular investigations and review of the literature.

Marco Gambarotti, Marina Pacheco, Poosit Ruengwanichayakun, Brayan Silvino Vega Jiménez, Stefania Benini, Giuseppe Bianchi, Marta Sbaraglia, Daniel Vanel, Elisa Carretta, Franco Bertoni, Alessandro Franchi, Angelo P Dei Tos, Alberto Righi,

AIMS:To evaluate the available diagnostic histological criteria for synovial chondrosarcoma and to screen for the presence of IDH1/IDH2 mutations in a series of cases of this malignant cartilaginous neoplasm. METHODS AND RESULTS:Ten cases of synovial chondrosarcoma diagnosed at our institute were reviewed. At presentation, all tumours occurred in adults (median ... Read more >>

Histopathology (Histopathology)
[2020, 77(3):391-401]

Cited: 1 time

View full text PDF listing >>



Enostosis, hyperostosis corticalis generalisata and possible overlap syndrome in a 7000 years old mummy from Libya.

Luca Ventura, Raffaele Gaeta, Virna Zampa, Giacomo Aringhieri, Gino Fornaciari, Savino Di Lernia, Mary Anne Tafuri, Giorgio Manzi, Alessandro Franchi,

Eur J Radiol (European journal of radiology)
[2020, 130:109183]

Cited: 0 times

View full text PDF listing >>



Precision medicine in rare tumors and the need for multicenter trials and international collaboratives: Sinonasal cancer as paradigm.

Paolo Bossi, Mario Hermsen, Matt Lechner, Alessandro Franchi,

Oral Oncol (Oral oncology)
[2020, 109:104737]

Cited: 0 times

View full text PDF listing >>



Dedifferentiated soft tissue leiomyosarcoma with heterologous osteosarcoma component: case report and review of the literature.

Raffaele Gaeta, Davide Matera, Francesco Muratori, Giuliana Roselli, Giacomo Baldi, Domenico Andrea Campanacci, Alessandro Franchi,

Background:Soft tissue dedifferentiated leiomyosarcoma with heterologous osteosarcomatous component is an extremely rare entity described in only few cases in the literature. Case presentation:We report the case of a 65-year-old male patient who, after initial inadequate surgery of a tumor of the left forearm, developed local recurrence that was treated with ... Read more >>

Clin Sarcoma Res (Clinical sarcoma research)
[2020, 10:6]

Cited: 0 times

View full text PDF listing >>



Diffuse bone and soft tissue angiomatosis with GNAQ mutation.

Raffaele Gaeta, Francesca Lessi, Chiara Mazzanti, Martina Modena, Alberto Garaventa, Silvio Boero, Maria Beatrice Michelis, Rodolfo Capanna, Paolo Aretini, Alessandro Franchi,

We describe a unique case of skeletal and extraskeletal angiomatosis complicated by Kasabach-Merritt syndrome. The patient was a 3-year-old boy, who presented with involvement of both femurs and left tibia, as well as with soft tissue lesions of the left thigh. At birth, multiple hemangiomas of the soft tissues of ... Read more >>

Pathol Int (Pathology international)
[2020, 70(7):452-457]

Cited: 1 time

View full text PDF listing >>



Ameloblastic fibrosarcoma: clinicopathological and molecular analysis of seven cases highlighting frequent BRAF and occasional NRAS mutations.

Abbas Agaimy, Alena Skalova, Alessandro Franchi, Rana Alshagroud, Anthony J Gill, Robert Stoehr, Daniel Baumhoer, Sebastian Bauer,

<h4>Aims</h4>Ameloblastic fibrosarcoma (AFS) is an aggressive odontogenic neoplasm featuring malignant mesenchymal stroma in addition to an ameloblastic epithelial component, and is hence considered to be the malignant counterpart of ameloblastic fibroma (AF). AFS is exceedingly rare, with <110 cases having been reported so far. Although BRAF mutations are recognised driver ... Read more >>

Histopathology (Histopathology)
[2020, 76(6):814-821]

Cited: 2 times

View full text PDF listing >>



ZNF687 Mutations in an Extended Cohort of Neoplastic Transformations in Paget's Disease of Bone: Implications for Clinical Pathology.

Federica Scotto di Carlo, Laura Pazzaglia, Steven Mumm, Maria S Benassi, Annarosaria De Chiara, Alessandro Franchi, Antonina Parafioriti, Alberto Righi, Teresa Esposito, Michael P Whyte, Fernando Gianfrancesco,

Neoplastic transformation is a rare but serious complication of Paget's disease of bone (PDB), occurring in fewer than 1% of individuals with polyostotic disease. Their prognosis is poor, with less than 50% surviving 5 years. In 2016, the genetic alteration of giant cell tumor (GCT) complicating PDB was identified as a ... Read more >>

J Bone Miner Res (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research)
[2020, 35(10):1974-1980]

Cited: 0 times

View full text PDF listing >>



IDH2 Mutation Analysis in Undifferentiated and Poorly Differentiated Sinonasal Carcinomas for Diagnosis and Clinical Management.

Cristina Riobello, Alejandro López-Hernández, Virginia N Cabal, Rocío García-Marín, Laura Suárez-Fernández, Paula Sánchez-Fernández, Blanca Vivanco, Verónica Blanco, Fernando López, Alessandro Franchi, José L Llorente, Mario A Hermsen,

A large number of tumor types arise from the mucosa of the sinonasal cavities. Although presenting clinically distinct behavior, due to poorly differentiated histologic features, they can be difficult to classify correctly. Our aim was to investigate whether IDH2 and IDH1 mutations may be specific to a subset of undifferentiated ... Read more >>

Am J Surg Pathol (The American journal of surgical pathology)
[2020, 44(3):396-405]

Cited: 1 time

View full text PDF listing >>



Sinonasal Undifferentiated Carcinoma (SNUC): From an Entity to Morphologic Pattern and Back Again-A Historical Perspective.

Abbas Agaimy, Alessandro Franchi, Valerie J Lund, Alena Skálová, Justin A Bishop, Asterios Triantafyllou, Simon Andreasen, Douglas R Gnepp, Henrik Hellquist, Lester D R Thompson, Alessandra Rinaldo, Alfio Ferlito,

Since the first description of sinonasal undifferentiated carcinoma (SNUC) as a distinctive highly aggressive sinonasal neoplasm with probable origin from the sinonasal mucosa (Schneiderian epithelium), SNUC has been the subject of ongoing study and controversy. In particular, the SNUC category gradually became a "wastebasket" for any undifferentiated or unclassifiable sinonasal ... Read more >>

Adv Anat Pathol (Advances in anatomic pathology)
[2020, 27(2):51-60]

Cited: 0 times

View full text PDF listing >>



Contribution of Raman Spectroscopy to Diagnosis and Grading of Chondrogenic Tumors.

Mario D'Acunto, Raffaele Gaeta, Rodolfo Capanna, Alessandro Franchi,

In the last decade, Raman Spectroscopy has demonstrated to be a label-free and non-destructive optical spectroscopy able to improve diagnostic accuracy in cancer diagnosis. This is because Raman spectroscopic measurements can reveal a deep molecular understanding of the biochemical changes in cancer tissues in comparison with non-cancer tissues. In this ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):2155]

Cited: 1 time

View full text PDF listing >>



Nomograms predictive for oncological outcomes in malignant parotid tumours: recurrence and mortality rates of 228 patients from a single institution.

Giuditta Mannelli, Franchi Alessandro, Fasolati Martina, Cecconi Lorenzo, Alessandra Bettiol, Alfredo Vannacci, Gallo Oreste,

<h4>Purpose</h4>Malignant parotid tumours are rare and multiple prognostic factors exist.<h4>Methods</h4>Through a retrospective study we aimed to identify nomograms predicting recurrence and mortality rates in 228 primary parotid cancers. Patients clinical, treatment and tumour characteristics were retrospectively collected between 1980 and 2005 at our Institution. Factors predictive of disease-free-specific-survival (DSS) and ... Read more >>

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2019, :]

Cited: 1 time

View full text PDF listing >>



Immunohistochemical profiling of mucins in sinonasal adenocarcinomas.

Cecilia Taverna, Giandomenico Maggiore, Angelo Cannavicci, Pierluigi Bonomo, Marco Santucci, Alessandro Franchi,

In this study we investigated the expression of mucins (MUC1, MUC2, MUC4, MUC5AC and MUC6) in a series of 66 sinonasal adenocarcinomas, in order to establish their distribution and the possible correlation with clinicopathological and prognostic parameters. The series included 51 intestinal type adenocarcinomas, 4 non-intestinal type adenocarcinomas, and 11 ... Read more >>

Pathol Res Pract (Pathology, research and practice)
[2019, 215(7):152439]

Cited: 0 times

View full text PDF listing >>



Data Set for the Reporting of Mucosal Melanomas of the Head and Neck: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting.

Michelle D Williams, Alessandro Franchi, Tim Helliwell, Susan Müller, Lester D R Thompson,

Standardized pathologic reporting for cancers allows for improved communication for patient care and prognostic determination. If used universally, synoptic reporting enhances comparing data globally for scientific leverage. The International Collaboration on Cancer Reporting is a nonprofit organization whose mission is to develop evidence-based, universally available surgical pathology reporting data sets. ... Read more >>

Arch Pathol Lab Med (Archives of pathology & laboratory medicine)
[2019, 143(5):603-609]

Cited: 0 times

View full text PDF listing >>



Data Set for the Reporting of Carcinomas of the Nasal Cavity and Paranasal Sinuses: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting.

Alessandro Franchi, Justin A Bishop, Hedley Coleman, Uta Flucke, Lisa F Licitra, José Luis Llorente Pendás, Edward B Stelow, Mary Toner, Ilan Weinreb, Bruce M Wenig, Lester D R Thompson,

The International Collaboration on Cancer Reporting was established to internationally unify and standardize the pathologic reporting of cancers based on collected evidence, as well as to allow systematic multi-institutional intercountry data collection to guide cancer care in the future. This data set has been developed by the collaborative efforts of ... Read more >>

Arch Pathol Lab Med (Archives of pathology & laboratory medicine)
[2019, 143(4):424-431]

Cited: 1 time

View full text PDF listing >>



Advertisement

Disclaimer
1.0691 s