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Author Alessandra Tavani

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Coffee consumption and colorectal cancer risk: a multicentre case-control study from Italy and Spain.

Valentina Rosato, Valentina Guercio, Cristina Bosetti, Esther Gracia-Lavedan, Cristina M Villanueva, Jerry Polesel, Federica Toffoluti, Victor Moreno, Vicente Martin, Nuria Aragonés, Trinidad Dierssen-Sotos, Rocío Olmedo-Requena, Marcela Guevara, Pilar Amiano, Dolores Salas, Guillermo Fernandez-Tardon, Juan Alguacil, María Dolores Chirlaque López, Tania Fernandez-Villa, Beatriz Pérez-Gómez, Ines Gomez-Acebo, Jose J Jiménez-Moleón, Conchi Moreno-Iribas, Antonio José Molina, Gemma Castaño Vinyals, Marina Pollan, Manolis Kogevinas, Carlo La Vecchia, Alessandra Tavani,

<h4>Background</h4>Coffee contains many bioactive substances that can play a role on colorectal cancer. Epidemiological evidence of coffee intake and colorectal cancer is, however, inconsistent.<h4>Aim</h4>To provide further information on the risk of colorectal cancer in relation to coffee consumption.<h4>Methods</h4>Data derive from two companion case-control studies conducted in Italy and Spain within ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2021, 30(3):204-210]

Cited: 0 times

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Plasma levels of polychlorinated biphenyls (PCB) and the risk of soft tissue sarcoma.

Valentina Guercio, Francesca Donato, Claudio Pelucchi, Federica Verga, Valter Passini, Carlotta Galeone, Eva Negri, Giacomo Garzaro, Paolo Boffetta, Carlo La Vecchia, Alessandra Tavani, Enrico Pira,

<h4>Background</h4>Soft tissue sarcoma (STS) is a heterogeneous group of rare neoplasms whose aetiology is largely unknown. Dioxin and dioxin-like compounds, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) and polychlorinated biphenyls (PCBs), are potential risk factors for STS.<h4>Objectives</h4>To investigate the relation of 17 PCBs congeners, assessed in human plasma, with STS risk.<h4>Methods</h4>We conducted a case-control ... Read more >>

Med Lav (La Medicina del lavoro)
[2019, 110(5):342-352]

Cited: 0 times

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The Mediterranean Diet and Cardiovascular Disease: Gaps in the Evidence and Research Challenges.

Norman J Temple, Valentina Guercio, Alessandra Tavani,

In this article, we critically evaluate the evidence relating to the effects of the Mediterranean diet (MD) on the risk of cardiovascular disease (CVD). Strong evidence indicating that the MD prevents CVD has come from prospective cohort studies. However, there is only weak supporting evidence from randomized controlled trials (RCTs) ... Read more >>

Cardiol Rev (Cardiology in review)
[2019, 27(3):127-130]

Cited: 6 times

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Bladder cancer risk in users of selected drugs for cardiovascular disease prevention.

Valentina Guercio, Federica Turati, Cristina Bosetti, Jerry Polesel, Diego Serraino, Maurizio Montella, Massimo Libra, Antonio Galfano, Carlo La Vecchia, Alessandra Tavani,

The aim of this study was to investigate the relation between bladder cancer risk and the use of selected drugs for cardiovascular disease (CVD) prevention, such as aspirin, statins, and calcium channel blockers (CCBs). We analyzed data from a multicentric case-control study carried out in Italy between 2003 and 2014, ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2019, 28(2):76-80]

Cited: 2 times

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Adherence to the Traditional Mediterranean Diet and Human Milk Composition: Rationale, Design, and Subject Characteristics of the MEDIDIET Study.

Guido E Moro, Enrico Bertino, Francesca Bravi, Paola Tonetto, Alberto Gatta, Pasqua A Quitadamo, Gugliemo Salvatori, Claudio Profeti, Paola Di Nicola, Adriano Decarli, Monica Ferraroni, Alessandra Tavani, Bernd Stahl, Frank Wiens,

Introduction: Knowledge about how a lactating woman's diet influences the composition of her breast milk is still very limited. In particular, no study has evaluated the role of adherence to the Mediterranean diet on human milk characteristics. Aim: We carried out an observational study to investigate the influence of mother ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:66]

Cited: 5 times

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Coffee Drinking and the Risk of Endometrial Cancer: An Updated Meta-Analysis of Observational Studies.

Marko Lukic, Neela Guha, Idlir Licaj, Piet A van den Brandt, Leslie Thomas Stayner, Alessandra Tavani, Elisabete Weiderpass,

BACKGROUND:Several compounds contained in coffee have been found to suppress carcinogenesis in experimental studies. We conducted a dose-response meta-analysis to assess the impact of coffee consumption on the risk of endometrial cancer. MATERIALS AND METHODS:We searched MEDLINE and EMBASE databases for studies published up to August 2016. Using random effects ... Read more >>

Nutr Cancer (Nutrition and cancer)
[2018, 70(4):513-528]

Cited: 6 times

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Dietary inflammatory index and acute myocardial infarction in a large Italian case-control study.

Nitin Shivappa, Alessandra Tavani, James R Hébert, Valentina Rosato, Carlo La Vecchia,

<h4>Background</h4>Diet and inflammation have been implicated to play a role in the incidence of acute myocardial infarction (AMI).<h4>Methods</h4>In this Italian case-control study conducted between 1995 and 2003, we explored the association between the dietary inflammatory index (DIITM) and AMI. Cases were 760 patients, below age 79 years, with a first ... Read more >>

Eur J Public Health (European journal of public health)
[2018, 28(1):161-166]

Cited: 7 times

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Mediterranean diet and cardiovascular disease: a systematic review and meta-analysis of observational studies.

Valentina Rosato, Norman J Temple, Carlo La Vecchia, Giorgio Castellan, Alessandra Tavani, Valentina Guercio,

<h4>Purpose</h4>To provide evidence of the relationship of Mediterranean diet (MD) on incidence/mortality for cardiovascular disease (CVD), coronary/ischemic heart disease (CHD)/acute myocardial infarction (AMI) and stroke (ischemic/hemorrhagic) by sex, geographic region, study design and type of MD score (MDS).<h4>Methods</h4>We performed a systematic review and meta-analysis of observational studies. Pooled relative risks (RRs) ... Read more >>

Eur J Nutr (European journal of nutrition)
[2019, 58(1):173-191]

Cited: 50 times

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Associations of dietary carbohydrates, glycaemic index and glycaemic load with risk of bladder cancer: a case-control study.

Livia S A Augustin, Martina Taborelli, Maurizio Montella, Massimo Libra, Carlo La Vecchia, Alessandra Tavani, Anna Crispo, Maria Grimaldi, Gaetano Facchini, David J A Jenkins, Gerardo Botti, Diego Serraino, Jerry Polesel,

Carbohydrate foods with high glycaemic index (GI) and load (GL) may negatively influence cancer risk. We studied the association of dietary carbohydrates, GI, GL, intake of bread and pasta with risk of bladder cancer using data from an Italian case-control study. The study included 578 men and women with histologically ... Read more >>

Br J Nutr (The British journal of nutrition)
[2017, 118(9):722-729]

Cited: 6 times

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Coffee and the risk of hepatocellular carcinoma and chronic liver disease: a systematic review and meta-analysis of prospective studies.

Francesca Bravi, Alessandra Tavani, Cristina Bosetti, Paolo Boffetta, Carlo La Vecchia,

An inverse association has been reported between coffee drinking and the risk of hepatocellular carcinoma (HCC) and chronic liver disease (CLD), but its magnitude is still unclear. Thus, we carried out a systematic review and meta-analysis of prospective cohort studies that investigated the association between coffee consumption and the risk ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2017, 26(5):368-377]

Cited: 30 times

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Adherence to the World Cancer Research Fund/American Institute for Cancer Research recommendations and colorectal cancer risk.

Federica Turati, Francesca Bravi, Matteo Di Maso, Cristina Bosetti, Jerry Polesel, Diego Serraino, Michela Dalmartello, Attilio Giacosa, Maurizio Montella, Alessandra Tavani, Eva Negri, Carlo La Vecchia,

<h4>Background</h4>The World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) released in 2007 eight recommendations for cancer prevention on body fatness, diet and physical activity. Our aim is to evaluate the relation between adherence to these recommendations and colorectal cancer (CRC) risk.<h4>Methods</h4>We pooled data from two Italian ... Read more >>

Eur J Cancer (European journal of cancer (Oxford, England : 1990))
[2017, 85:86-94]

Cited: 24 times

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Coffee and cancer risk: a summary overview.

Gianfranco Alicandro, Alessandra Tavani, Carlo La Vecchia,

We reviewed available evidence on coffee drinking and the risk of all cancers and selected cancers updated to May 2016. Coffee consumption is not associated with overall cancer risk. A meta-analysis reported a pooled relative risk (RR) for an increment of 1 cup of coffee/day of 1.00 [95% confidence interval (CI): ... Read more >>

Eur J Cancer Prev (European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP))
[2017, 26(5):424-432]

Cited: 17 times

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Processed Meat and Colorectal Cancer Risk: A Pooled Analysis of Three Italian Case-Control Studies.

Valentina Rosato, Alessandra Tavani, Eva Negri, Diego Serraino, Maurizio Montella, Adriano Decarli, Carlo La Vecchia, Monica Ferraroni,

To add evidence to the limited data available from southern Europe, we assessed the association between processed meat consumption and colorectal cancer risk. We analyzed data from three case-control studies conducted between 1985 and 2010 in various Italian areas, including a total of 3745 incident cases and 6804 hospital-based controls. ... Read more >>

Nutr Cancer (Nutrition and cancer)
[2017, 69(5):732-738]

Cited: 4 times

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Family history of cancer and the risk of bladder cancer: A case-control study from Italy.

Federica Turati, Cristina Bosetti, Jerry Polesel, Diego Serraino, Maurizio Montella, Massimo Libra, Gaetano Facchini, Monica Ferraroni, Alessandra Tavani, Carlo La Vecchia, Eva Negri,

<h4>Background</h4>A family history of bladder cancer has been associated with the risk of bladder cancer, but quantification of the excess risk in different populations is still a relevant issue. Further, the role of a family history of other cancers on the risk of bladder cancer remains unclear.<h4>Methods</h4>We analyzed data from ... Read more >>

Cancer Epidemiol (Cancer epidemiology)
[2017, 48:29-35]

Cited: 7 times

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Frequency of Pregnancy Related Cancer: A Population Based Linkage Study in Lombardy, Italy.

Fabio Parazzini, Matteo Franchi, Alessandra Tavani, Eva Negri, Fedro Alessandro Peccatori,

<h4>Objectives</h4>The aims of this study were to estimate the occurrence of pregnancy-associated cancer overall and by site, to evaluate if the risk increases over time, and to investigate some major determinants.<h4>Methods</h4>This is a population-based linkage study using the regional hospital discharge forms [Scheda di Dimissione Ospedaliera (SDO)] database of Lombardy, ... Read more >>

Int J Gynecol Cancer (International journal of gynecological cancer : official journal of the International Gynecological Cancer Society)
[2017, 27(3):613-619]

Cited: 20 times

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Dietary water intake and bladder cancer risk: An Italian case-control study.

Matteo Di Maso, Cristina Bosetti, Martina Taborelli, Maurizio Montella, Massimo Libra, Antonella Zucchetto, Federica Turati, Maria Parpinel, Eva Negri, Alessandra Tavani, Diego Serraino, Monica Ferraroni, Carlo La Vecchia, Jerry Polesel,

Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based ... Read more >>

Cancer Epidemiol (Cancer epidemiology)
[2016, 45:151-156]

Cited: 7 times

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Type 2 Diabetes, Antidiabetic Medications, and Colorectal Cancer Risk: Two Case-Control Studies from Italy and Spain.

Valentina Rosato, Alessandra Tavani, Esther Gracia-Lavedan, Elisabet Guinó, Gemma Castaño-Vinyals, Cristina M Villanueva, Manolis Kogevinas, Jerry Polesel, Diego Serraino, Federica E Pisa, Fabio Barbone, Victor Moreno, Carlo La Vecchia, Cristina Bosetti,

<h4>Background</h4>Type 2 diabetes mellitus has been associated with an excess risk of colorectal cancer, although the time-risk relationship is unclear, and there is limited information on the role of antidiabetic medications.<h4>Aim</h4>We examined the association between type 2 diabetes, antidiabetic medications, and the risk of colorectal cancer, considering also duration of ... Read more >>

Front Oncol (Frontiers in oncology)
[2016, 6:210]

Cited: 10 times

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Mediterranean diet and colorectal cancer risk: a pooled analysis of three Italian case-control studies.

Valentina Rosato, Valentina Guercio, Cristina Bosetti, Eva Negri, Diego Serraino, Attilio Giacosa, Maurizio Montella, Carlo La Vecchia, Alessandra Tavani,

<h4>Background</h4>Adherence to the Mediterranean diet (MD) is associated with a reduced risk of several cancers. However, studies conducted in Mediterranean regions are scanty.<h4>Methods</h4>To investigate the relation between MD and colorectal cancer risk in Italy, we pooled data from three case-control studies, including a total of 3745 colorectal cancer cases and ... Read more >>

Br J Cancer (British journal of cancer)
[2016, 115(7):862-865]

Cited: 22 times

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Dietary antioxidant capacity and risk for stroke in a prospective cohort study of Swedish men and women.

Luca Colarusso, Mauro Serafini, Ylva Trolle Lagerros, Olof Nyren, Carlo La Vecchia, Marta Rossi, Weimin Ye, Alessandra Tavani, Hans-Olov Adami, Alessandra Grotta, Rino Bellocco,

<h4>Objective</h4>Both observational studies and randomized trials have shown that a diet rich in antioxidants can reduce systemic inflammation and oxidative stress, two conditions that, together with obesity and smoking, are established risk factors for stroke. However, the association between antioxidant intake and risk for stroke is poorly understood, particularly when ... Read more >>

Nutrition (Nutrition (Burbank, Los Angeles County, Calif.))
[2017, 33:234-239]

Cited: 7 times

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Colorectal Cancer and Long-Term Exposure to Trihalomethanes in Drinking Water: A Multicenter Case-Control Study in Spain and Italy.

Cristina M Villanueva, Esther Gracia-Lavedan, Cristina Bosetti, Elena Righi, Antonio José Molina, Vicente Martín, Elena Boldo, Nuria Aragonés, Beatriz Perez-Gomez, Marina Pollan, Ines Gomez Acebo, Jone M Altzibar, Ana Jiménez Zabala, Eva Ardanaz, Rosana Peiró, Adonina Tardón, Maria Dolores Chirlaque, Alessandra Tavani, Jerry Polesel, Diego Serraino, Federica Pisa, Gemma Castaño-Vinyals, Ana Espinosa, Nadia Espejo-Herrera, Margarita Palau, Victor Moreno, Carlo La Vecchia, Gabriella Aggazzotti, Mark J Nieuwenhuijsen, Manolis Kogevinas,

<h4>Background</h4>Evidence on the association between colorectal cancer and exposure to disinfection by-products in drinking water is inconsistent.<h4>Objectives</h4>We assessed long-term exposure to trihalomethanes (THMs), the most prevalent group of chlorination by-products, to evaluate the association with colorectal cancer.<h4>Methods</h4>A multicenter case-control study was conducted in Spain and Italy in 2008-2013. Hospital-based incident ... Read more >>

Environ Health Perspect (Environmental health perspectives)
[2017, 125(1):56-65]

Cited: 9 times

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Colorectal cancer risk and nitrate exposure through drinking water and diet.

Nadia Espejo-Herrera, Esther Gràcia-Lavedan, Elena Boldo, Nuria Aragonés, Beatriz Pérez-Gómez, Marina Pollán, Antonio J Molina, Tania Fernández, Vicente Martín, Carlo La Vecchia, Cristina Bosetti, Alessandra Tavani, Jerry Polesel, Diego Serraino, Inés Gómez Acebo, Jone M Altzibar, Eva Ardanaz, Rosana Burgui, Federica Pisa, Guillermo Fernández-Tardón, Adonina Tardón, Rosana Peiró, Carmen Navarro, Gemma Castaño-Vinyals, Victor Moreno, Elena Righi, Gabriella Aggazzotti, Xavier Basagaña, Mark Nieuwenhuijsen, Manolis Kogevinas, Cristina M Villanueva,

Ingested nitrate leads to the endogenous synthesis of N-nitroso compounds (NOCs), animal carcinogens with limited human evidence. We aimed to evaluate the risk of colorectal cancer (CRC) associated with nitrate exposure in drinking water and diet. A case-control study in Spain and Italy during 2008-2013 was conducted. Hospital-based incident cases ... Read more >>

Int J Cancer (International journal of cancer)
[2016, 139(2):334-346]

Cited: 19 times

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Dietary total antioxidant capacity and pancreatic cancer risk: an Italian case-control study.

Aimee L Lucas, Cristina Bosetti, Paolo Boffetta, Eva Negri, Alessandra Tavani, Mauro Serafini, Jerry Polesel, Diego Serraino, Carlo La Vecchia, Marta Rossi,

<h4>Background</h4>Pancreatic cancer is one of the leading causes of cancer mortality. Diet may be associated with pancreatic cancer, but it is unknown whether specific dietary components contribute to its risk. The potential differential role of dietary antioxidants warrants further investigation.<h4>Methods</h4>We analysed data from a case-control study of 326 pancreatic cancer ... Read more >>

Br J Cancer (British journal of cancer)
[2016, 115(1):102-107]

Cited: 10 times

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Dietary total antioxidant capacity in relation to endometrial cancer risk: a case-control study in Italy.

Marta Rossi, Alessandra Tavani, Valentina Ciociola, Monica Ferraroni, Maria Parpinel, Mauro Serafini, Rino Bellocco, Antonella Zucchetto, Maurizio Montella, Diego Serraino, Pagona Lagiou, Carlo La Vecchia,

<h4>Purpose</h4>To investigate the role of the overall antioxidant activity of diet, we estimated the relation between three dietary indices of total antioxidant capacity (TAC) and endometrial cancer risk<h4>Methods</h4>We analyzed data from an Italian case-control study including 454 women with incident, histologically confirmed endometrial cancer, and 908 frequency-matched controls admitted to ... Read more >>

Cancer Causes Control (Cancer causes & control : CCC)
[2016, 27(3):425-431]

Cited: 3 times

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Allium vegetables and upper aerodigestive tract cancers: a meta-analysis of observational studies.

Valentina Guercio, Federica Turati, Carlo La Vecchia, Carlotta Galeone, Alessandra Tavani,

<h4>Scope</h4>To provide updated quantitative overall estimations of the relation between total allium, garlic, and onion intake on the risk of cancer of the upper aerodigestive tract (UADT).<h4>Methods and results</h4>We combined data of published observational studies (21 case-control and four cohort studies), using a meta-analytic approach and random effects models. The ... Read more >>

Mol Nutr Food Res (Molecular nutrition & food research)
[2016, 60(1):212-222]

Cited: 7 times

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Coffee, Tea, Cola, and Bladder Cancer Risk: Dose and Time Relationships.

Federica Turati, Cristina Bosetti, Jerry Polesel, Antonella Zucchetto, Diego Serraino, Maurizio Montella, Massimo Libra, Antonio Galfano, Carlo La Vecchia, Alessandra Tavani,

<h4>Objective</h4>To further analyze the relation between coffee, tea, and energy drinks and bladder cancer risk, considering dose, duration, and other time-related factors.<h4>Methods and results</h4>A multicentric case-control study on 690 bladder cancer cases and 665 hospital controls was conducted in Italy between 2003 and 2014. Odds ratios (ORs) for bladder cancer ... Read more >>

Urology (Urology)
[2015, 86(6):1179-1184]

Cited: 9 times

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