Full Text Journal Articles by
Author Aleksandr Voskoboinik

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Ventricular arrhythmias in heart failure with reduced ejection fraction.

Aleksandr Voskoboinik, Joshua D Moss,

PURPOSE OF REVIEW:To provide a framework for approaching ventricular arrhythmias in the setting of cardiomyopathy, outline the latest evidence-based recommendations for catheter ablation and device therapy, and discuss novel treatment strategies. RECENT FINDINGS:Risk stratification of ventricular arrhythmias in systolic heart failure has evolved, with an increasing role for cardiac magnetic ... Read more >>

Curr. Opin. Cardiol. (Current opinion in cardiology)
[2020, 35(3):282-288]

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Alcohol Abstinence in Drinkers with Atrial Fibrillation. Reply.

Peter M Kistler, Aleksandr Voskoboinik,

N. Engl. J. Med. (The New England journal of medicine)
[2020, 382(18):1768-1769]

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Predictors of adverse outcome in patients with frequent premature ventricular complexes: The ABC-VT risk score.

Aleksandr Voskoboinik, Alexios Hadjis, Christina Alhede, Sung Il Im, Hansu Park, Joshua Moss, Gregory M Marcus, Henry Hsia, Byron Lee, Zian Tseng, Randall Lee, Melvin Scheinman, Vasanth Vedantham, Eric Vittinghoff, Kyoung-Min Park, Edward P Gerstenfeld,

BACKGROUND:No independently validated score currently exists for risk stratification of patients with frequent premature ventricular contractions (PVCs). OBJECTIVES:The purpose of this study was to develop a risk score to predict adverse events in patients with frequent PVCs. METHODS:We analyzed consecutive patients between 2012 and 2017 undergoing 14-day continuous monitoring with ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, :]

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Direct Thrombin Inhibitors as an Alternative to Heparin During Catheter Ablation: A Multicenter Experience.

Aleksandr Voskoboinik, Eric Butcher, Amneet Sandhu, Duy T Nguyen, Wendy Tzou, Domenico G Della Rocca, Andrea Natale, Erica S Zado, Francis E Marchlinski, Martin Aguilar, William Sauer, Usha B Tedrow, Edward P Gerstenfeld,

OBJECTIVES:The goal of this study was to report a multicenter series of left-sided catheter ablations performed by using intravenous direct thrombin inhibitors (DTIs) as an alternative to heparin. BACKGROUND:Amidst a looming worldwide shortage of heparin, there are insufficient data to guide nonheparin-based peri-procedural anticoagulation in patients undergoing catheter ablation. METHODS:This ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2020, 6(5):484-490]

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Arrhythmia recurrence is more common in females undergoing multiple catheter ablation procedures for persistent atrial fibrillation: Time to close the gender gap.

Hariharan Sugumar, Shane Nanayakkara, David Chieng, Geoffrey R Wong, Ramanathan Parameswaran, Robert D Anderson, Ahmed Al-Kaisey, Chrishan J Nalliah, Sonia Azzopardi, Sandeep Prabhu, Aleksandr Voskoboinik, Geoffrey Lee, Alex J McLellan, Liang-Han Ling, Joseph B Morton, Jonathan M Kalman, Peter M Kistler,

BACKGROUND:Female gender is associated with an increased recurrence of atrial fibrillation (AF) after catheter ablation (CA). Although AF is more common in men, women constitute a significant proportion with persistent atrial fibrillation (PsAF). OBJECTIVE:The purpose of this study was to determine whether multiple ablation procedures improves arrhythmia outcomes in females ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(5 Pt A):692-698]

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Alcohol Abstinence in Drinkers with Atrial Fibrillation.

Aleksandr Voskoboinik, Jonathan M Kalman, Anurika De Silva, Thomas Nicholls, Benedict Costello, Shane Nanayakkara, Sandeep Prabhu, Dion Stub, Sonia Azzopardi, Donna Vizi, Geoffrey Wong, Chrishan Nalliah, Hariharan Sugumar, Michael Wong, Emily Kotschet, David Kaye, Andrew J Taylor, Peter M Kistler,

BACKGROUND:Excessive alcohol consumption is associated with incident atrial fibrillation and adverse atrial remodeling; however, the effect of abstinence from alcohol on secondary prevention of atrial fibrillation is unclear. METHODS:We conducted a multicenter, prospective, open-label, randomized, controlled trial at six hospitals in Australia. Adults who consumed 10 or more standard drinks ... Read more >>

N. Engl. J. Med. (The New England journal of medicine)
[2020, 382(1):20-28]

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Anatomic Considerations for Epicardial and Endocardial Left Atrial Appendage Closure.

Aleksandr Voskoboinik, Randall J Lee,

Left atrial appendage closure is an increasingly used means of achieving thromboprophylaxis in atrial fibrillation, particularly in patients with contraindications to anticoagulation. Left atrial appendage anatomy is highly variable, and preprocedural imaging is critical to choosing the correct device and approach for left atrial appendage closure. This article reviews the ... Read more >>

Card Electrophysiol Clin (Cardiac electrophysiology clinics)
[2020, 12(1):39-45]

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The many faces of early repolarization syndrome: A single-center case series.

Aleksandr Voskoboinik, Henry Hsia, Joshua Moss, Vasanth Vedantham, Ronn E Tanel, Akash Patel, Julianne Wojciak, Natalie Downs, Melvin M Scheinman,

BACKGROUND:Early repolarization syndrome (ERS) is a rare but increasingly recognized cause of malignant ventricular arrhythmias. OBJECTIVE:The purpose of this study was to characterize the presentations and treatments of ERS at our institution. METHODS:We performed a retrospective chart review of all patients presenting to our institution between 2008 and 2019 with ... Read more >>

Heart Rhythm (Heart rhythm)
[2020, 17(2):273-281]

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Differentiating Right- and Left-Sided Outflow Tract Ventricular Arrhythmias: Classical ECG Signatures and Prediction Algorithms.

Robert D Anderson, Saurabh Kumar, Ramanathan Parameswaran, Geoffrey Wong, Aleksandr Voskoboinik, Hariharan Sugumar, Troy Watts, Paul B Sparks, Joseph B Morton, Alex McLellan, Peter M Kistler, Jonathan Kalman, Geoffrey Lee,

Idiopathic ventricular arrhythmias commonly originate from the right ventricular and left ventricular outflow tracts (OTs). Advances in real-time imaging have refined our understanding of the intimate anatomic structures implicated in the genesis of OT arrhythmias, making catheter ablation for arrhythmias beyond the right ventricular OT a feasible option for cure-indeed ... Read more >>

Circ Arrhythm Electrophysiol (Circulation. Arrhythmia and electrophysiology)
[2019, 12(6):e007392]

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Dynamic Atrial Substrate During High-Density Mapping of Paroxysmal and Persistent AF: Implications for Substrate Ablation.

Geoffrey R Wong, Chrishan J Nalliah, Geoffrey Lee, Aleksandr Voskoboinik, Sandeep Prabhu, Ramanathan Parameswaran, Hariharan Sugumar, Robert D Anderson, Alex McLellan, Liang-Han Ling, Joseph B Morton, Prashanthan Sanders, Peter M Kistler, Jonathan M Kalman,

OBJECTIVES:This study sought to determine the impact of rate and direction on left atrial (LA) substrate. BACKGROUND:The extent to which substrate mapped in sinus rhythm varies according to cycle length and direction of wave front propagation is unknown. METHODS:A total of 73 consecutive patients with atrial fibrillation (AF) underwent electroanatomic ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2019, 5(11):1265-1277]

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Author's reply: Caffeinated beverages and cardiovascular disease.

Aleksandr Voskoboinik, Peter M Kistler,

Trends Cardiovasc. Med. (Trends in cardiovascular medicine)
[2019, 29(8):484]

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Atrial Remodeling Following Catheter Ablation for Atrial Fibrillation-Mediated Cardiomyopathy: Long-Term Follow-Up of CAMERA-MRI Study.

Hariharan Sugumar, Sandeep Prabhu, Aleksandr Voskoboinik, Shane Young, Sarah J Gutman, Geoffrey R Wong, Ramanathan Parameswaran, Chrishan J Nalliah, Geoff Lee, Alex J McLellan, Andrew J Taylor, Liang-Han Ling, Jonathan M Kalman, Peter M Kistler,

OBJECTIVES:This study sought to determine the long-term right atrial (RA) electrical and structural changes in a subgroup from the CAMERA-MRI (Catheter Ablation Versus Medical Rate Control in Atrial Fibrillation and Systolic Dysfunction-Magnetic Resonance Imaging) study. BACKGROUND:Catheter ablation (CA) is successful in restoring ventricular function in patients with atrial fibrillation (AF) ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2019, 5(6):681-688]

Cited: 1 time

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RESPONSE TO LETTER TO EDITOR.

Aleksandr Voskoboinik, Peter M Kistler,

J. Cardiovasc. Electrophysiol. (Journal of cardiovascular electrophysiology)
[2019, 30(9):1764]

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Moderate alcohol consumption is associated with atrial electrical and structural changes: Insights from high-density left atrial electroanatomic mapping.

Aleksandr Voskoboinik, Geoffrey Wong, Geoff Lee, Chrishan Nalliah, Joshua Hawson, Sandeep Prabhu, Hariharan Sugumar, Liang-Han Ling, Alex McLellan, Joseph Morton, Jonathan M Kalman, Peter M Kistler,

BACKGROUND:Regular alcohol intake is an important modifiable risk factor associated with atrial fibrillation (AF) and left atrial (LA) dilation. OBJECTIVE:The purpose of this study was to determine the impact of different degrees of alcohol consumption on atrial remodeling using high-density electroanatomic mapping. METHODS:We enrolled 75 patients before AF ablation to ... Read more >>

Heart Rhythm (Heart rhythm)
[2019, 16(2):251-259]

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Reply to the Editor- Mediterranean diet and wine intake could improve atrial function in patients with atrial fibrillation.

Aleksandr Voskoboinik, Peter M Kistler,

Heart Rhythm (Heart rhythm)
[2019, 16(8):e55-e56]

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Pathophysiology of Atrial Fibrillation and Heart Failure: Dangerous Interactions.

Hariharan Sugumar, Shane Nanayakkara, Sandeep Prabhu, Aleksandr Voskoboinik, David M Kaye, Liang-Han Ling, Peter M Kistler,

Atrial fibrillation and heart failure (HF) frequently coexist and are associated with a significant increase in morbidity and mortality. Despite the shared common risk factors atrial fibrillation and HF subtypes exacerbate each other. This review provides an overview of the pathophysiologic relationship between atrial fibrillation and the two most common ... Read more >>

Cardiol Clin (Cardiology clinics)
[2019, 37(2):131-138]

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Reduction in mortality from implantable cardioverter-defibrillators in non-ischaemic cardiomyopathy patients is dependent on the presence of left ventricular scar.

Sarah J Gutman, Benedict T Costello, Stavroula Papapostolou, Aleksandr Voskoboinik, Leah Iles, Johnson Ja, James L Hare, Andris Ellims, Peter M Kistler, Thomas H Marwick, Andrew J Taylor,

Aims:In patients with non-ischaemic cardiomyopathy (NICM), the mortality benefit of a primary prevention implantable cardioverter-defibrillator (ICD) has been challenged. Left ventricular (LV) scar identified by cardiac magnetic resonance (CMR) imaging is associated with a high risk of malignant arrhythmia in NICM. We aimed to determine the impact of LV scar ... Read more >>

Eur. Heart J. (European heart journal)
[2019, 40(6):542-550]

Cited: 1 time

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A comparison of early versus delayed elective electrical cardioversion for recurrent episodes of persistent atrial fibrillation: A multi-center study.

Aleksandr Voskoboinik, Elana Kalman, George Plunkett, Jonathan Knott, Jeremy Moskovitch, Prashanthan Sanders, Peter M Kistler, Jonathan M Kalman,

BACKGROUND:Due to barriers to accessing timely elective electrical cardioversion (CV) for persistent AF (PeAF), we adopted a policy of instructing patients to present directly to the Emergency Department (ED) for CV. OBJECTIVE:We compare a strategy of Emergency CV (ED-CV) versus Elective CV (EL-CV) for treatment of symptomatic PeAF. METHODS:Between 2014 ... Read more >>

Int. J. Cardiol. (International journal of cardiology)
[2019, 284:33-37]

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Cardiac resynchronization therapy: a comprehensive review.

Jeremy Moskovitch, Aleksandr Voskoboinik,

Despite improved understanding of heart failure (HF) and advances in medical treatments, its prevalence continues to rise, and the role of implantable devices continues to evolve. While cardiac resynchronization therapy (CRT) is an accepted form of treatment for many suffering from HF, there is an ever-evolving body of evidence examining ... Read more >>

Minerva Med. (Minerva medica)
[2019, 110(2):121-138]

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Cardioversion of atrial fibrillation in obese patients: Results from the Cardioversion-BMI randomized controlled trial.

Aleksandr Voskoboinik, Jeremy Moskovitch, George Plunkett, Jason Bloom, Geoffrey Wong, Chrishan Nalliah, Sandeep Prabhu, Hariharan Sugumar, Ramanathan Paramasweran, Alex McLellan, Liang-Han Ling, Cheng-Yee Goh, Samer Noaman, Himawan Fernando, Michael Wong, Andrew J Taylor, Jonathan M Kalman, Peter M Kistler,

AIMS:Obesity is associated with higher electrical cardioversion (ECV) failure in persistent atrial fibrillation (PeAF). For ease-of-use, many centers prefer patches over paddles. We assessed the optimum modality and shock vector, as well as the safety and efficacy of the Manual Pressure Augmentation (MPA) technique. METHODS:Patients with obesity (BMI ≥ 30) and PeAF ... Read more >>

J. Cardiovasc. Electrophysiol. (Journal of cardiovascular electrophysiology)
[2019, 30(2):155-161]

Cited: 2 times

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Relation of Alcohol Consumption to Left Ventricular Fibrosis Using Cardiac Magnetic Resonance Imaging.

Aleksandr Voskoboinik, Benedict T Costello, Andre La Gerche, Sandeep Prabhu, Geoff Wong, Michael D Flannery, Chrishan Nalliah, Hariharan Sugumar, Fabian Springer, Jonathan M Kalman, Andrew J Taylor, Peter M Kistler,

Light-to-moderate regular alcohol consumption has been associated with reduced mortality, heart failure, and sudden death, with a well described "U-shaped" relationship. We sought to determine whether markers of diffuse ventricular fibrosis as assessed by cardiac magnetic resonance imaging (CMR) T1 mapping differ between nondrinkers and regular drinkers. We prospectively recruited ... Read more >>

Am. J. Cardiol. (The American journal of cardiology)
[2019, 123(3):460-465]

Cited: 0 times

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Absence of late gadolinium enhancement on cardiac magnetic resonance imaging in ventricular fibrillation and nonischemic cardiomyopathy.

Aleksandr Voskoboinik, Michael C G Wong, Jessica K Elliott, Benedict T Costello, Sandeep Prabhu, Justin A Mariani, Jonathan M Kalman, Peter M Kistler, Andrew J Taylor, Joseph B Morton,

INTRODUCTION:Cardiac magnetic resonance (CMR)-identified late gadolinium enhancement (LGE), representing regional fibrosis, is often used to predict ventricular arrhythmia risk in nonischemic cardiomyopathy (NICM). However, LGE is more closely correlated with sustained monomorphic ventricular tachycardia (SMVT) than ventricular fibrillation (VF). We characterized CMR findings of ventricular LGE in VF survivors. METHODS:We ... Read more >>

Pacing Clin Electrophysiol (Pacing and clinical electrophysiology : PACE)
[2018, 41(9):1109-1115]

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Regular Alcohol Consumption Is Associated With Impaired Atrial Mechanical Function in the Atrial Fibrillation Population: A Cross-Sectional MRI-Based Study.

Aleksandr Voskoboinik, Benedict T Costello, Elana Kalman, Sandeep Prabhu, Hariharan Sugumar, Geoff Wong, Chrishan Nalliah, Liang-Han Ling, Alex McLellan, Thushan Hettige, Fabian Springer, Andre La Gerche, Jonathan M Kalman, Andrew J Taylor, Peter M Kistler,

OBJECTIVES:This study sought to determine the impact of regular alcohol consumption on left atrial (LA) mechanical and reservoir function. BACKGROUND:Earlier studies suggest that regular alcohol intake is associated with increased atrial fibrillation (AF) and LA dilatation. METHODS:This study prospectively enrolled 160 patients with paroxysmal or persistent AF to undergo 3-T ... Read more >>

JACC Clin Electrophysiol (JACC. Clinical electrophysiology)
[2018, 4(11):1451-1459]

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Cardiovascular effects of caffeinated beverages.

Aleksandr Voskoboinik, Youlin Koh, Peter M Kistler,

Caffeine is the world's most popular 'drug', with tea and coffee a ubiquitous part of daily life. As a psychoactive stimulant, there are potential concerns regarding adverse cardiovascular squeal. Cardiovascular conditions, encompassing hypertension, coronary artery disease, rhythm disorders and heart failure affect billions of patients worldwide. We aim to provide ... Read more >>

Trends Cardiovasc. Med. (Trends in cardiovascular medicine)
[2019, 29(6):345-350]

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Clinical impact of rotor ablation in atrial fibrillation: a systematic review.

Ramanathan Parameswaran, Aleksandr Voskoboinik, Alexandra Gorelik, Geoffrey Lee, Peter M Kistler, Prashanthan Sanders, Jonathan M Kalman,

Aims:Rotor mapping and ablation have gained favour over the recent years as an emerging ablation strategy targeting drivers of atrial fibrillation (AF). Their efficacy, however, has been a topic of great debate with variable outcomes across centres. The aim of this study was to systematically review the recent medical literature ... Read more >>

Europace (Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology)
[2018, 20(7):1099-1106]

Cited: 7 times

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