Full Text Journal Articles by
Author Alberto Martini

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Salvage Robot-assisted Renal Surgery for Local Recurrence After Surgical Resection or Renal Mass Ablation: Classification, Techniques, and Clinical Outcomes.

Alberto Martini, Filippo Turri, Ravi Barod, Bernardo Rocco, Umberto Capitanio, Alberto Briganti, Francesco Montorsi, Alexandre Mottrie, Ben Challacombe, Brunolf W Lagerveld, Karim Bensalah, Ronney Abaza, Ketan K Badani, Reza Mehrazin, Maurizio Buscarini, Alessandro Larcher, ,

<h4>Background</h4>Salvage treatment for local recurrence after prior partial nephrectomy (PN) or local tumor ablation (LTA) for kidney cancer is, as of yet, poorly investigated.<h4>Objective</h4>To classify the treatments and standardize the nomenclature of salvage robot-assisted renal surgery, to describe the surgical technique for each scenario, and to investigate complications, renal function, ... Read more >>

Eur Urol (European urology)
[2021, :]

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Oncologic Surveillance for Variant Histology Bladder Cancer after Radical Cystectomy.

Alberto Martini, Luca Afferi, Stefania Zamboni, Julianne G Schultz, Chiara Lonati, Agostino Mattei, R Jeffrey Karnes, Matteo Soligo, Armando Stabile, Ettore Di Trapani, Ottavio De Cobelli, Giuseppe Simone, Claudio Simeone, Mario Alvarez-Maestro, Giorgio Gandaglia, Andrea Gallina, Renzo Colombo, Alberto Briganti, Francesco Montorsi, Evanguelos Xylinas, Shahrokh F Shariat, Marco Moschini,

<h4>Purpose</h4>Presently, major guidelines do not provide specific recommendations on oncologic surveillance for patients who harbor VH BCa at radical cystectomy. We aimed to create a personalized follow-up scheme that dynamically weighs OCM versus the risk of recurrence for VH BCa, and to compare it with a similar one for pUC.<h4>Methods</h4>Within ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001886]

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Time for change at PROJ in 2021.

Charles H Spencer, Alberto Martini,

Pediatr Rheumatol Online J (Pediatric rheumatology online journal)
[2021, 19(1):65]

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The effect of tumor location on overall survival for pT2-4 bladder and upper tract urothelial carcinoma following radical surgery.

Andrew W Tam, Christine Liaw, Eric Li, Andrew B Katims, Rollin K Say, Zeynep Gul, Jared S Winoker, Alberto Martini, Francois Audenet, John P Sfakianos,

<h4>Introduction</h4>Historically, staging and treatment for upper tract urothelial carcinoma were extrapolated from bladder urothelial carcinoma literature. However, embryological, genetic, and anatomical differences exist between them. We sought to explore the relationship between location of urothelial cancer and overall survival (OS).<h4>Methods</h4>Data was culled from the National Cancer Database from 2004-2015. Patients ... Read more >>

Can Urol Assoc J (Canadian Urological Association journal = Journal de l'Association des urologues du Canada)
[2021, 15(5):E248-E255]

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Publisher Correction: Biological classification of childhood arthritis: roadmap to a molecular nomenclature.

Peter A Nigrovic, Robert A Colbert, V Michael Holers, Seza Ozen, Nicolino Ruperto, Susan D Thompson, Lucy R Wedderburn, Rae S M Yeung, Alberto Martini,

Nat Rev Rheumatol (Nature reviews. Rheumatology)
[2021, 17(5):306]

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Reducing the Risk of Postoperative Complications After Robot-assisted Radical Prostatectomy in Prostate Cancer Patients: Results of an Audit and Feedback Intervention Following the Implementation of Prospective Data Collection.

Giuseppe Rosiello, Giorgio Gandaglia, Simone Scuderi, Francesco Barletta, Nicola Fossati, Armando Stabile, Andrea Gallina, Elio Mazzone, Luca Maria Vitale, Antony Pellegrino, Carlo Bravi, Alberto Martini, Vito Cucchiara, Pierre I Karakiewicz, Alexandre Mottrie, Alberto Briganti, Francesco Montorsi,

<h4>Background</h4>Prospective data collection for perioperative outcomes might increase awareness of surgical results obtained for patients with prostate cancer (PCa) undergoing robot-assisted radical prostatectomy (RARP). This would prompt the implementation of measures aimed at reducing the risk of adverse outcomes.<h4>Objective</h4>To assess the efficacy of an audit and feedback process aimed at ... Read more >>

Eur Urol Focus (European urology focus)
[2021, :]

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Metastatic hormone-sensitive prostate cancer: local treatment strategies.

Francesco Montorsi, Alberto Martini, Giorgio Gandaglia, Nicola Fossati, Armando Stabile, Federico Dehò, Andrea Salonia, Alberto Briganti,

World J Urol (World journal of urology)
[2021, :]

Cited: 1 time

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Biological classification of childhood arthritis: roadmap to a molecular nomenclature.

Peter A Nigrovic, Robert A Colbert, V Michael Holers, Seza Ozen, Nicolino Ruperto, Susan D Thompson, Lucy R Wedderburn, Rae S M Yeung, Alberto Martini,

Chronic inflammatory arthritis in childhood is heterogeneous in presentation and course. Most forms exhibit clinical and genetic similarity to arthritis of adult onset, although at least one phenotype might be restricted to children. Nevertheless, paediatric and adult rheumatologists have historically addressed disease classification separately, yielding a juvenile idiopathic arthritis (JIA) nomenclature ... Read more >>

Nat Rev Rheumatol (Nature reviews. Rheumatology)
[2021, 17(5):257-269]

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Predicting toxicity-related docetaxel discontinuation and overall survival in metastatic castration-resistant prostate cancer: a pooled analysis of open phase 3 clinical trial data.

Alberto Martini, Anish B Parikh, John P Sfakianos, Francesco Montorsi, Matthew D Galsky, William K Oh, Che-Kai Tsao,

<h4>Background</h4>Docetaxel is widely used in metastatic castration-resistant prostate cancer (mCRPC), however its optimal use remains unclear in the current treatment landscape. Biomarkers to predict Docetaxel toxicity may help optimize treatment selection. We aimed to create a predictive model for toxicity-related Docetaxel discontinuation (TRDD).<h4>Methods</h4>Through Project Data Sphere, we accessed individual patient ... Read more >>

Prostate Cancer Prostatic Dis (Prostate cancer and prostatic diseases)
[2021, :]

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Efficacy and Safety of Tocilizumab for Polyarticular-Course Juvenile Idiopathic Arthritis in the Open-Label Two-Year Extension of a Phase III Trial.

Hermine I Brunner, Nicolino Ruperto, Zbigniew Zuber, Rubén Cuttica, Vladimir Keltsev, Ricardo M Xavier, Ruben Burgos-Vargas, Inmaculada Calvo Penades, Earl D Silverman, Graciela Espada, Manuel Ferrandiz Zavaler, Yukiko Kimura, Carolina Duarte, Chantal Job-Deslandre, Rik Joos, Wendy Douglass, Sunethra Wimalasundera, Kamal N Bharucha, Chris Wells, Daniel J Lovell, Alberto Martini, Fabrizio de Benedetti, ,

<h4>Objective</h4>To report the 2-year efficacy and safety of tocilizumab (TCZ) in patients with polyarticular-course juvenile idiopathic arthritis (JIA).<h4>Methods</h4>Patients ages 2-17 years with active polyarticular-course JIA, in whom treatment with methotrexate was unsuccessful, received 16 weeks of open-label intravenous TCZ in part 1 (once every 4 weeks: 8 mg/kg or 10 ... Read more >>

Arthritis Rheumatol (Arthritis & rheumatology (Hoboken, N.J.))
[2021, 73(3):530-541]

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Re: Mathieu Rouanne, Dean F. Bajorin, Raquibul Hannan, et al. Rationale and Outcomes for Neoadjuvant Immunotherapy in Urothelial Carcinoma of the Bladder. Eur Urol Oncol 2020;3:728-38.

Francesco Montorsi, Alberto Martini,

Eur Urol Oncol (European urology oncology)
[2021, 4(2):336]

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Open-Label Phase 3 Study of Intravenous Golimumab in Patients With Polyarticular Juvenile Idiopathic Arthritis.

Nicolino Ruperto, Hermine I Brunner, César Pacheco-Tena, Ingrid Louw, Gabriel Vega-Cornejo, Alberto J Spindler, Daniel J Kingsbury, Heinrike Schmeling, Arturo Borzutzky, Rubén Cuttica, C J Inman, Victor Malievskiy, Christiaan Scott, Vladimir Keltsev, Maria Teresa Terreri, Diego Oscar Viola, Ricardo M Xavier, Taciana A Pedrosa Fernandes, María Del Rocío Maldonado Velázquez, Michael Henrickson, Michael B Clark, Karen A Bensley, Xiaoming Li, Kim Hung Lo, Jocelyn H Leu, Chyi-Hung Hsu, Elizabeth C Hsia, Zhenhua Xu, Alberto Martini, Daniel J Lovell, ,

<h4>Objectives</h4>Assess efficacy, pharmacokinetics (PK), and safety of intravenous (IV) golimumab in patients with polyarticular-course juvenile idiopathic arthritis (pc-JIA).<h4>Methods</h4>Children aged 2 to < 18 years with active pc-JIA despite methotrexate therapy for ≥2 months received 80 mg/m2 golimumab at Weeks 0, 4, then every 8 weeks through week 52 plus methotrexate weekly through week 28. The primary ... Read more >>

Rheumatology (Oxford) (Rheumatology (Oxford, England))
[2021, :]

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Subcutaneous dosing regimens of tocilizumab in children with systemic or polyarticular juvenile idiopathic arthritis.

Nicolino Ruperto, Hermine I Brunner, Athimalaipet V Ramanan, Gerd Horneff, Rubén Cuttica, Michael Henrickson, Jordi Anton, Alina Lucica Boteanu, Inmaculada Calvo Penades, Kirsten Minden, Heinrike Schmeling, Markus Hufnagel, Jennifer E Weiss, Manuela Pardeo, Kabita Nanda, Johannes Roth, Nadina Rubio-Pérez, Joy C Hsu, Sunethra Wimalasundera, Chris Wells, Kamal Bharucha, Wendy Douglass, Min Bao, Navita L Mallalieu, Alberto Martini, Daniel Lovell, Fabrizio De Benedetti, ,

<h4>Objectives</h4>To determine subcutaneous-tocilizumab (SC-TCZ) dosing regimens for systemic juvenile idiopathic arthritis (sJIA) and polyarticular JIA (pJIA).<h4>Methods</h4>In two 52-week phase 1 b trials, SC-TCZ (162 mg/dose) was administered to sJIA patients every week or every 2 weeks (every 10 days before interim analysis) and to pJIA patients every 2 weeks or every 3 weeks with body weight ... Read more >>

Rheumatology (Oxford) (Rheumatology (Oxford, England))
[2021, :]

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Absence of Association Between Abatacept Exposure and Initial Infection in Patients With Juvenile Idiopathic Arthritis.

Nicolino Ruperto, Hermine I Brunner, Nikolay Tzaribachev, Gabriel Vega-Cornejo, Ingrid Louw, Rolando Cimaz, Jason Dare, Graciela Espada, Enrique Faugier, Manuel Ferrandiz, Valeria Gerloni, Pierre Quartier, Clovis Artur Silva, Linda Wagner-Weiner, Yash Gandhi, Julie Passarell, Marleen Nys, Robert Wong, Alberto Martini, Daniel J Lovell, ,

<h4>Objective</h4>To assess the relationship between infection risk and abatacept (ABA) exposure levels in patients with polyarticular-course juvenile idiopathic arthritis (pJIA) following treatment with subcutaneous (SC) and intravenous (IV) ABA.<h4>Methods</h4>Data from 2 published studies (ClinicalTrials.gov: NCT01844518, NCT00095173) of ABA treatment in pediatric patients were analyzed. One study treated patients aged 2-17 ... Read more >>

J Rheumatol (The Journal of rheumatology)
[2021, :]

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Population-Attributable-Fraction":-application-in-cost-estimation.">On the use of the "Population Attributable Fraction": application in cost estimation.

Alberto Martini,

Transl Androl Urol (Translational andrology and urology)
[2021, 10(1):22-23]

Cited: 0 times

Population-Attributable-Fraction":-application-in-cost-estimation.">View full text PDF listing >>



Neoadjuvant and adjuvant immunotherapy in renal cell carcinoma.

Alberto Martini, Giuseppe Fallara, Francesco Pellegrino, Giuseppe Ottone Cirulli, Alessandro Larcher, Andrea Necchi, Francesco Montorsi, Umberto Capitanio,

<h4>Objective</h4>The treatment landscape for renal cell carcinoma (RCC) is rapidly evolving. The aim of this review is to summarize the randomized-controlled trials evaluating the role of immunotherapy in neoadjuvant or adjuvant setting.<h4>Materials and methods</h4>We searched PubMed, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov for studies including neoadjuvant or adjuvant ... Read more >>

World J Urol (World journal of urology)
[2021, 39(5):1369-1376]

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Tapering Canakinumab Monotherapy in Patients With Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results From a Phase IIIb/IV Open-Label, Randomized Study.

Pierre Quartier, Ekaterina Alexeeva, Tamàs Constantin, Vyacheslav Chasnyk, Nico Wulffraat, Karin Palmblad, Carine Wouters, Hermine I Brunner, Katherine Marzan, Rayfel Schneider, Gerd Horneff, Alberto Martini, Jordi Anton, Xiaoling Wei, Alan Slade, Nicolino Ruperto, Ken Abrams, ,

<h4>Objective</h4>To evaluate the efficacy and safety of 2 canakinumab monotherapy tapering regimens in order to maintain complete clinical remission in children with systemic juvenile idiopathic arthritis (JIA).<h4>Methods</h4>The study was designed as a 2-part phase IIIb/IV open-label, randomized trial. In the first part, patients received 4 mg/kg of canakinumab subcutaneously every ... Read more >>

Arthritis Rheumatol (Arthritis & rheumatology (Hoboken, N.J.))
[2021, 73(2):336-346]

Cited: 2 times

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RE: Validating the Martini Staging System for Rectourethral Fistula: A Meta-analysis of Postoperative Outcomes.

Alberto Martini, Giorgio Gandaglia, Giulio Nicita, Francesco Montorsi,

Urology (Urology)
[2021, 147:323]

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Editorial Comment from Dr Martini et al. to Independent external validation of a nomogram to define risk categories for a significant decline in estimated glomerular filtration rate after robotic-assisted partial nephrectomy.

Alberto Martini, Ugo Giovanni Falagario, Carlo Andrea Bravi, Ronney Abaza, Daniel D Eun, Akshay Bhandari, James R Porter, Umberto Capitanio, Francesco Montorsi, Ashok K Hemal, Ketan K Badani,

Int J Urol (International journal of urology : official journal of the Japanese Urological Association)
[2021, 28(1):80-81]

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Efficacy and Safety of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis With and Without Fever at Baseline: Results From an Open-Label, Active-Treatment Extension Study.

Hermine I Brunner, Pierre Quartier, Ekaterina Alexeeva, Tamàs Constantin, Isabelle Koné-Paut, Katherine Marzan, Rayfel Schneider, Nico M Wulffraat, Vyacheslav Chasnyk, Irit Tirosh, Tilmann Kallinich, Jasmin Kuemmerle-Deschner, Carine Wouters, Bernard Lauwerys, Irina Nikishina, Maria Trachana, Olga Vougiouka, Alberto Martini, Daniel J Lovell, Jeremy Levy, Eleni Vritzali, Nicolino Ruperto, ,

<h4>Objective</h4>To evaluate the long-term efficacy and safety of canakinumab and explore prediction of response in patients with systemic juvenile idiopathic arthritis (JIA) with or without fever at treatment initiation.<h4>Methods</h4>At enrollment, patients with active systemic JIA (ages 2 to <20 years) started open-label canakinumab (4 mg/kg every 4 weeks subcutaneously). Efficacy ... Read more >>

Arthritis Rheumatol (Arthritis & rheumatology (Hoboken, N.J.))
[2020, 72(12):2147-2158]

Cited: 2 times

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Abatacept: A Review of the Treatment of Polyarticular-Course Juvenile Idiopathic Arthritis.

Hermine I Brunner, Robert Wong, Marleen Nys, Tzuyung D Kou, Alyssa Dominique, Alberto Martini, Daniel J Lovell, Nicolino Ruperto, ,

Juvenile idiopathic arthritis (JIA) encompasses several forms of chronic inflammatory arthritis of unknown etiology presenting in children < 16 years of age, with a minimum symptom duration of 6 weeks. Approximately half of affected children have polyarticular-course JIA (pJIA), a functional concept related to several clinically and genetically heterogeneous JIA categories (systemic, extended oligoarthritis, ... Read more >>

Paediatr Drugs (Paediatric drugs)
[2020, 22(6):653-672]

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Hood Technique for Robotic Radical Prostatectomy-Preserving Periurethral Anatomical Structures in the Space of Retzius and Sparing the Pouch of Douglas, Enabling Early Return of Continence Without Compromising Surgical Margin Rates.

Vinayak G Wagaskar, Ankur Mittal, Stanislaw Sobotka, Parita Ratnani, Anna Lantz, Ugo Giovanni Falagario, Alberto Martini, Zach Dovey, Patrick-Julien Treacy, Prachee Pathak, Suit Nair, Berryhill Roy, Dimple Chakravarty, Sara Lewis, Kenneth Haines, Peter Wiklund, Ash Tewari,

<h4>Background</h4>A common side effect following radical prostatectomy is urinary incontinence. Here, we describe a novel surgical technique to reduce postoperative urinary incontinence and facilitate early return of continence.<h4>Objective</h4>To describe the novel "hood technique" for robotic-assisted radical prostatectomy (RARP).<h4>Design, setting, and participants</h4>This is an institutional review board-approved prospective study of 300 ... Read more >>

Eur Urol (European urology)
[2020, :]

Cited: 1 time

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How to Select the Optimal Candidates for Renal Mass Biopsy.

Alberto Martini, Alessandro Larcher, Carlo Andrea Bravi, Paolo Capogrosso, Ugo Giovanni Falagario, Giuseppe Fallara, Francesco Pellegrino, Fabio Muttin, Chiara Re, Alberto Briganti, Andrea Salonia, Roberto Bertini, Francesco Montorsi, Umberto Capitanio, ,

Surgical treatment of small renal masses (RMs) is still characterized by a non-negligible rate of benign histology, ultimately resulting in overtreatment. Since the risk of kidney cancer increases with age and the risk of malignancy usually increases with tumor size, we created a model based on patient age, RM size, ... Read more >>

Eur Urol Oncol (European urology oncology)
[2021, 4(3):506-509]

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Fused Omics Data Models Reveal Gut Microbiome Signatures Specific of Inactive Stage of Juvenile Idiopathic Arthritis in Pediatric Patients.

Pamela Vernocchi, Federico Marini, Giorgio Capuani, Alberta Tomassini, Giorgia Conta, Federica Del Chierico, Clara Malattia, Fabrizio De Benedetti, Alberto Martini, Bruno Dallapiccola, E H Pieter van Dijkhuizen, Alfredo Miccheli, Lorenza Putignani,

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. Herein, we evaluated the relationship between the gut microbiome (GM) and disease phenotype by an integrated omics fused approach. In a multicenter, observational cohort study, stools from Italian JIA patients were collected at baseline, active, and inactive disease ... Read more >>

Microorganisms (Microorganisms)
[2020, 8(10):]

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Using biomarkers in patients with positive multiparametric magnetic resonance imaging: 4Kscore predicts the presence of cancer outside the index lesion.

Ugo Giovanni Falagario, Anna Lantz, Ivan Jambor, Alberto Martini, Parita Ratnani, Vinayak Wagaskar, Patrick-Julien Treacy, Alessandro Veccia, Carlo Andrea Bravi, Hafis O Bashorun, Deron Phillip, Sara Lewis, Kenneth Haines, Luigi Cormio, Giuseppe Carrieri, Ash Tewari,

<h4>Objectives</h4>To evaluate if the blood biomarker, 4Kscore, in addition to multiparametric magnetic resonance imaging information could identify patients who would benefit from undergoing only a targeted biopsy.<h4>Methods</h4>We retrospectively analyzed a population of 256 men with positive multiparametric magnetic resonance imaging who underwent standard + targeted biopsy at Mount Sinai Hospital, New York, ... Read more >>

Int J Urol (International journal of urology : official journal of the Japanese Urological Association)
[2021, 28(1):47-52]

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