Full Text Journal Articles by
Author Alain Michel


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Exposure of human fetal kidneys to mild analgesics interferes with early nephrogenesis.

Sabrina Leverrier-Penna, Alain Michel, Laetitia L Lecante, Nathalie Costet, Antonio Suglia, Christèle Desdoits-Lethimonier, Hugoline Boulay, Roselyne Viel, Jonathan M Chemouny, Emmanuelle Becker, Vincent Lavoué, Antoine D Rolland, Nathalie Dejucq-Rainsford, Cécile Vigneau, Séverine Mazaud-Guittot,

Acetaminophen, aspirin, and ibuprofen are mild analgesics commonly used by pregnant women, the sole current recommendation being to avoid ibuprofen from the fifth month of gestation. The nephrotoxicity of these three analgesics is well documented in adults, as is their interference with prostaglandins biosynthesis. Here we investigated the effect of ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2021, 35(7):e21718]

Cited: 0 times

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[ANCA-vasculitis with renal impairment treated by intravenous versus oral cyclophosphamide: Multicentric analysis of relapse free survival (VaReCyS)].

Jean-Baptiste Gouin, Thibault Dhalluin, Régine Perrichot, Cécile Vigneau, Alain Michel,

<h4>Introduction</h4>ANCA-vasculitis are associated with high morbidity and mortality. Large use of cyclophosphamide as induction immunosuppressive therapy is limited by its side effects. All recent literature trends in decreasing cumulative dose while optimizing maintenance therapy.<h4>Methods</h4>This retrospective multicentric analysis included ANCA-vasculitis patients with renal impairment and de novo diagnose followed in Rennes ... Read more >>

Nephrol Ther (Nephrologie & therapeutique)
[2020, 16(4):201-210]

Cited: 0 times

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[Hypokalemia with pseudo-hyperaldosteronism: Is it Lidl® syndrome?]

Gabriel Eustache, Alain Michel, Léonard Golbin, Cécile Vigneau,

INTRODUCTION:Intoxication induced by glycyrrhizin is a common cause of hypokalaemia by pseudo-hyperaldosteronism. OBSERVATION:We hereby present the observation of a 68-year old patient hospitalised following a full hip-prosthesis operation after a deep hypokalaemia at 2.5mM was observed, with ECG signs (flat T waves and appearance of U waves). The kaliuresis was ... Read more >>

Nephrol Ther (Nephrologie & therapeutique)
[2020, 16(4):225-231]

Cited: 0 times

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Antioxidant and Anti-Inflammatory Potential of Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Sporophores from Various Culture Conditions.

Ibrahima Diallo, Frédéric Boudard, Sylvie Morel, Manon Vitou, Caroline Guzman, Nathalie Saint, Alain Michel, Sylvie Rapior, Lonsény Traoré, Patrick Poucheret, Françoise Fons,

Lentinus edodes (= Lentinula edodes) is an edible mushroom grown and marketed for centuries due to its nutritional and medicinal properties. L. edodes has multiple pharmacological activities as an antioxidant and anti-inflammatory. Few studies were performed taking into account the influence of culture conditions to optimize the biological properties of ... Read more >>

Int J Med Mushrooms (International journal of medicinal mushrooms)
[2020, 22(6):535-546]

Cited: 0 times

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Correction to: Deleterious effects of dialysis emergency start, insights from the French REIN registry.

Alain Michel, Adelaide Pladys, Sahar Bayat, Cécile Couchoud, Thierry Hannedouche, Cécile Vigneau,

Following publication of the original article [1], the authors reported that all of the authors' names were processed incorrectly so that their given and family names were interchanged. ... Read more >>

BMC Nephrol (BMC nephrology)
[2018, 19(1):266]

Cited: 0 times

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Deleterious effects of dialysis emergency start, insights from the French REIN registry.

Alain Michel, Adelaide Pladys, Sahar Bayat, Cécile Couchoud, Thierry Hannedouche, Cécile Vigneau,

<h4>Background</h4>Emergency start (ES) of dialysis has been associated with worse outcome, but remains poorly documented. This study aims to compare the profile and outcome of a large cohort of patients starting dialysis as an emergency or as a planned step in France.<h4>Methods</h4>Data on all patients aged 18 years or older ... Read more >>

BMC Nephrol (BMC nephrology)
[2018, 19(1):233]

Cited: 5 times

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Pulmonary anti-inflammatory effects and spasmolytic properties of Costa Rican noni juice (Morinda citrifolia L.).

Emilie Dussossoy, Florence Bichon, Emilie Bony, Karine Portet, Pierre Brat, Fabrice Vaillant, Alain Michel, Patrick Poucheret,

<h4>Ethnopharmacological relevance</h4>Morinda citrifolia L. (Noni) is a medicinal plant used in Polynesia for many properties such as anti-inflammatory, anti-diabetic and antineoplastic effects. Recent studies showed that noni juice have anti-oxidant and acute anti-inflammatory activities likely due to polyphenols, iridoids and vitamin C content. The present study was undertaken to evaluate ... Read more >>

J Ethnopharmacol (Journal of ethnopharmacology)
[2016, 192:264-272]

Cited: 6 times

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Pasteurization of blackberry juice preserves polyphenol-dependent inhibition for lipid peroxidation and intracellular radicals

Gabriela Azofeifa, Silvia Quesada, Ana M Pérez, Fabrice Vaillant, Alain Michel,

Berries are commonly consumed as juice, and juice-processing conditions could affect their bioactive compounds. This study evaluated the effect of thermal treatments on the antioxidant capacity of blackberry juice polyphenols. Pasteurized blackberry juices were prepared at 75°C for 15s (JP75) and 92°C for 10s (JP92). Polyphenol analysis showed that for ... Read more >>

J Food Compost Anal (Journal of food composition and analysis : an official publication of the United Nations University, International Network of Food Data Systems)
[2015, 42:56-62]

Cited: 1 time

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Antioxidant and anti-inflammatory in vitro activities of phenolic compounds from tropical highland blackberry (Rubus adenotrichos).

Gabriela Azofeifa, Silvia Quesada, Frederic Boudard, Marion Morena, Jean-Paul Cristol, Ana M Pérez, Fabrice Vaillant, Alain Michel,

This study evaluates the antioxidant and anti-inflammatory activities in a polyphenol extract from blackberries. The antioxidant activity measured via oxygen radical absorbance capacity (ORAC) was higher for the blackberry extract (4339 ± 144 μM TE/g) than for quercetin and ellagic acid. The blackberry phenolic compounds protected liposomes and liver homogenates ... Read more >>

J Agric Food Chem (Journal of agricultural and food chemistry)
[2013, 61(24):5798-5804]

Cited: 7 times

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Chemical composition and anti-inflammatory properties of the unsaponifiable fraction from awara (Astrocaryum vulgare M.) pulp oil in activated J774 macrophages and in a mice model of endotoxic shock.

Emilie Bony, Frédéric Boudard, Emilie Dussossoy, Karine Portet, Pierre Brat, Jean Giaimis, Alain Michel,

Awara (Astrocaryum vulgare M.) pulp oil has been shown to possess anti-inflammatory properties in vivo, and contains an unsaponifiable matter rich in bioactive compounds. This study focused on the ethanolic unsaponifiable fraction (EUF) of awara pulp oil. Its chemical composition has been characterized: carotenoid, phytosterol, and tocopherol contents represent 125.7, ... Read more >>

Plant Foods Hum Nutr (Plant foods for human nutrition (Dordrecht, Netherlands))
[2012, 67(4):384-392]

Cited: 2 times

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Awara (Astrocaryum vulgare M.) pulp oil: chemical characterization, and anti-inflammatory properties in a mice model of endotoxic shock and a rat model of pulmonary inflammation.

Emilie Bony, Frédéric Boudard, Pierre Brat, Emilie Dussossoy, Karine Portet, Patrick Poucheret, Jean Giaimis, Alain Michel,

Awara (Astrocaryum vulgare M.) is a palm fruit mainly used in nutrition. We analysed the pulp oil for fatty acid, tocopherol, carotenoid, and phytosterol and we evaluated whether this oil may attenuate inflammation in vivo. In an endotoxic shock model, awara pulp oil treatment decreased pro-inflammatory cytokines and increased anti-inflammatory ... Read more >>

Fitoterapia (Fitoterapia)
[2012, 83(1):33-43]

Cited: 7 times

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Anti-inflammatory properties of desipramine and fluoxetine.

Caroline Roumestan, Alain Michel, Florence Bichon, Karine Portet, Maëlle Detoc, Corinne Henriquet, Dany Jaffuel, Marc Mathieu,

BACKGROUND: Antidepressants are heavily prescribed drugs and have been shown to affect inflammatory signals. We examined whether these have anti-inflammatory properties in animal models of septic shock and allergic asthma. We also analysed whether antidepressants act directly on peripheral cell types that participate in the inflammatory response in these diseases. ... Read more >>

Respir Res (Respiratory research)
[2007, 8:35]

Cited: 108 times

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Ventilation during air breathing and in response to hypercapnia in 5 and 16 month-old mdx and C57 mice.

Jerome Gayraud, Stefan Matecki, Karim Hnia, Dominique Mornet, Christian Prefaut, Jacques Mercier, Alain Michel, Michele Ramonatxo,

Previous studies have shown a blunted ventilatory response to hypercapnia in mdx mice older than 7 months. We test the hypothesis that in the mdx mice ventilatory response changes with age, concomitantly with the increased functional impairment of the respiratory muscles. We thus studied the ventilatory response to CO(2) in ... Read more >>

J Muscle Res Cell Motil (Journal of muscle research and cell motility)
[2007, 28(1):29-37]

Cited: 16 times

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Addressing suicidal ideations through the realization of meaningful personal goals.

Sylvie Lapierre, Micheline Dubé, Léandre Bouffard, Michel Alain,

A personal goal intervention program was offered to early retirees aged 50 to 65 years with the objective of increasing their subjective well-being. The program was aimed at helping the participants set, plan, pursue, and realize their personal goals. A subsample of 21 participants with suicidal ideas was identified from ... Read more >>

Crisis (Crisis)
[2007, 28(1):16-25]

Cited: 18 times

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A new peptidic vector for molecular imaging of apoptosis, identified by phage display technology.

Catherine Laumonier, Jérôme Segers, Sophie Laurent, Alain Michel, Frédérique Coppée, Alexandra Belayew, Luce Vander Elst, Robert N Muller,

Phosphatidylserine (PS) exposure on the cell surface is an early marker of apoptosis. To select PS binding peptides as vectors of contrast agents to image apoptosis, a phage library has been exposed to perfused mouse livers. Phages not retained on control livers during the first perfusions were used for selections ... Read more >>

J Biomol Screen (Journal of biomolecular screening)
[2006, 11(5):537-545]

Cited: 29 times

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Building extraction from stereoscopic aerial images.

Hélène Oriot, Alain Michel,

Three-dimensional models of urban objects are widely used in geographic information systems, telecommunications, or defense applications. The classic technique for obtaining such models is stereoscopy. Images are densely matched, and images of above-ground structures are delineated. We propose two semiautomatic methods based on the Hough transform and statistically active models ... Read more >>

Appl Opt (Applied optics)
[2004, 43(2):218-226]

Cited: 1 time

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The effect of respiratory muscle training with CO2 breathing on cellular adaptation of mdx mouse diaphragm.

Stefan Matecki, François Rivier, Gerald Hugon, Christelle Koechlin, Alain Michel, Christian Prefaut, Dominique Mornet, Michele Ramonatxo,

The aim of our study was to investigate the cellular mechanisms induced by hypercapnic stimulation of ventilation, during 6 weeks/30 min per day, in 10 mdx and 8 C57BL10 mice (10+/-0.2 months old). Ten mdx and eight C57BL10 mice served as control group. This respiratory training increases in vitro maximal ... Read more >>

Neuromuscul Disord (Neuromuscular disorders : NMD)
[2005, 15(6):427-436]

Cited: 7 times

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[Mental health through management of personal projects: an intervention with young retired people].

Micheline Dubé, Léandre Bouffard, Sylvie Lapierre, Michel Alain,

A personal goal-based intervention was offered to retired people aged 50 to 65 years with the objective of increasing their subjective well-being and their mental health. More specifically, the program presented here was aimed to promote the setting, planning, and realization of personal projects through a learning process based on ... Read more >>

Sante Ment Que (Sante mentale au Quebec)
[2005, 30(2):321-344]

Cited: 1 time

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Differential effects of sodium tungstate and vanadyl sulfate on vascular responsiveness to vasoactive agents and insulin sensitivity in fructose-fed rats.

Najim Al-Awwadi, Florence Bichon-Laurent, Théophile Dimo, Alain Michel, Karine Portet, Gérard Cros, Patrick Poucheret,

High fructose feeding induces insulin resistance, impaired glucose tolerance, and hypertension in rats and mimics most of the features of the metabolic syndrome X. The effects of a 6-week treatment with the transition metals administered in drinking water, vanadium (VOSO4.5H2O, 0.75 mg/mL) or tungsten (Na2O4W, 2 g/mL), were investigated on ... Read more >>

Can J Physiol Pharmacol (Canadian journal of physiology and pharmacology)
[2004, 82(10):911-918]

Cited: 4 times

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