Full Text Journal Articles by
Author Akiko Komori

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Normal reference values for left atrial strains and strain rates in school children assessed using two-dimensional speckle-tracking echocardiography.

Shino Jimbo, Nobutaka Noto, Hirotsugu Okuma, Masataka Kato, Akiko Komori, Mamoru Ayusawa, Ichiro Morioka,

Left atrium (LA) function is a known predictive marker of heart failure in adults. Few reports of LA function analyses using LA strain (ɛ) and strain rate (SR) measurements in children exist. Thus, this study aimed to determine normal reference values for LA ɛ and SR in healthy school children ... Read more >>

Heart Vessels (Heart and vessels)
[2020, :]

Cited: 0 times

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Efficacy of primary treatment with immunoglobulin plus ciclosporin for prevention of coronary artery abnormalities in patients with Kawasaki disease predicted to be at increased risk of non-response to intravenous immunoglobulin (KAICA): a randomised controlled, open-label, blinded-endpoints, phase 3 trial.

Hiromichi Hamada, Hiroyuki Suzuki, Yoshihiro Onouchi, Ryota Ebata, Masaru Terai, Shigeto Fuse, Yoshitomo Okajima, Shunji Kurotobi, Katsuki Hirai, Takashi Soga, Yukiko Ishiguchi, Yoshiaki Okuma, Nobuyuki Takada, Masaaki Yanai, Junichi Sato, Mami Nakayashiro, Mamoru Ayusawa, Eiichi Yamamoto, Yuichi Nomura, Yuya Hashimura, Kazunobu Ouchi, Hiroshi Masuda, Shinichi Takatsuki, Keiichi Hirono, Tadashi Ariga, Takashi Higaki, Akio Otsuki, Moe Terauchi, Reiko Aoyagi, Takatoshi Sato, Yasuhisa Fujii, Tadami Fujiwara, Hideki Hanaoka, Akira Hata, ,

BACKGROUND:Genetic studies have indicated possible involvement of the upregulated calcium-nuclear factor of activated T cells pathway in the pathogenesis of Kawasaki disease. We aimed to assess safety and efficacy of ciclosporin, an immunosuppressant targeting this pathway, for protection of patients with Kawasaki disease against coronary artery abnormalities. METHODS:We did a ... Read more >>

Lancet (Lancet (London, England))
[2019, 393(10176):1128-1137]

Cited: 4 times

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Safety and accuracy of the Rhythmia mapping system in pediatric patients.

Hitoshi Mori, Shota Muraji, Naokata Sumitomo, Ritsushi Kato, Tomohiko Imamura, Akiko Komori, Noriyuki Iwashita, Toshiki Kobayashi, Kazuo Matsumoto,

BACKGROUND:A new mapping system (Rhythmia) using a 64 mini-electrode small basket array (Orion) was developed that enables rapid high-density mapping in a short time. However, there are few reports about the usefulness of this system in pediatric cases. OBJECTIVE:The purpose of this study was to investigate the safety and accuracy ... Read more >>

Heart Rhythm (Heart Rhythm)
[2019, 16(3):388-394]

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Appropriate use of a beta-blocker in paediatric coronary CT angiography.

Hirofumi Watanabe, Hiroshi Kamiyama, Masataka Kato, Akiko Komori, Yuriko Abe, Mamoru Ayusawa,

BACKGROUND:There is no standard dose or protocol for beta-blocker administration as preconditioning in children undergoing coronary CT angiography. METHODS:A total of 63 consecutive patients, with a mean age of 10.0±3.1 years, who underwent coronary CT angiography to assess possible coronary complications were enrolled in a single-centre, retrospective study. All patients ... Read more >>

Cardiol Young (Cardiology in the young)
[2018, 28(10):1148-1153]

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Association of Severity of Coronary Artery Aneurysms in Patients With Kawasaki Disease and Risk of Later Coronary Events.

Masaru Miura, Tohru Kobayashi, Tetsuji Kaneko, Mamoru Ayusawa, Ryuji Fukazawa, Naoya Fukushima, Shigeto Fuse, Kenji Hamaoka, Keiichi Hirono, Taichi Kato, Yoshihide Mitani, Seiichi Sato, Shinya Shimoyama, Junko Shiono, Kenji Suda, Hiroshi Suzuki, Jun Maeda, Kenji Waki, , Hitoshi Kato, Tsutomu Saji, Hiroyuki Yamagishi, Aya Ozeki, Masako Tomotsune, Makiko Yoshida, Yohei Akazawa, Kentaro Aso, Shouzaburoh Doi, Yoshi Fukasawa, Kenji Furuno, Yasunobu Hayabuchi, Miyuki Hayashi, Takafumi Honda, Norihisa Horita, Kazuyuki Ikeda, Masahiro Ishii, Satoru Iwashima, Masahiro Kamada, Masahide Kaneko, Hiroshi Katyama, Yoichi Kawamura, Atushi Kitagawa, Akiko Komori, Kenji Kuraishi, Hiroshi Masuda, Shinichi Matsuda, Satoshi Matsuzaki, Sayaka Mii, Tomoyuki Miyamoto, Yuji Moritou, Noriko Motoki, Kiyoshi Nagumo, Tsuneyuki Nakamura, Eiki Nishihara, Yuichi Nomura, Shohei Ogata, Hiroyuki Ohashi, Kenichi Okumura, Daisuke Omori, Tetsuya Sano, Eisuke Suganuma, Tsutomu Takahashi, Shinichi Takatsuki, Atsuhito Takeda, Masaru Terai, Manatomo Toyono, Kenichi Watanabe, Makoto Watanabe, Masaki Yamamoto, Kenichiro Yamamura,

Importance:Few studies with sufficient statistical power have shown the association of the z score of the coronary arterial internal diameter with coronary events (CE) in patients with Kawasaki disease (KD) with coronary artery aneurysms (CAA). Objective:To clarify the association of the z score with time-dependent CE occurrence in patients with ... Read more >>

JAMA Pediatr (JAMA pediatrics)
[2018, 172(5):e180030]

Cited: 3 times

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A Combination Therapy for Kawasaki Disease with Severe Complications: a Case Report.

Yuriko Abe, Mamoru Ayusawa, Kengo Kawamura, Ryuta Yonezawa, Masataka Kato, Akiko Komori, Ryutaro Kohira, Ichiro Morioka,

Kawasaki disease (KD) is a form of acute multisystem vasculitis that presents with various complications, including coronary artery aneurysm. Heart failure and brain damage are rare, but life-threatening complications are associated with KD. Here, we describe a 4-year-old girl who developed intravenous immunoglobulin-resistant KD with both left ventricular failure and ... Read more >>

Open Med (Wars) (Open medicine (Warsaw, Poland))
[2018, 15:8-13]

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Cardiac function on 3-D speckle tracking imaging and cytokines in Kawasaki disease.

Masataka Kato, Mamoru Ayusawa, Hirofumi Watanabe, Akiko Komori, Yuriko Abe, Takahiro Nakamura, Hiroshi Kamiyama, Shori Takahashi,

Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) tends to rise in acute phase Kawasaki disease (KD), but the cause of NT-proBNP elevation has not been clarified. In a previous study, cardiac function evaluated on 2-D echocardiography (2D-E) such as ejection fraction was normal, but this does not reflect subtle changes in ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2018, 60(4):342-348]

Cited: 2 times

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Recent updates on echocardiography and ultrasound for Kawasaki disease: beyond the coronary artery.

Nobutaka Noto, Akiko Komori, Mamoru Ayusawa, Shori Takahashi,

Kawasaki disease (KD) is a systemic vasculitis with a predilection for damage to the coronary arteries. In the acute phase, clinical decision making for KD relies on the measurements of the coronary z-score obtained by 2-dimensional echocardiography (2DE). In the convalescent phase, KD patients with coronary artery abnormalities (CAAs) eventually ... Read more >>

Cardiovasc Diagn Ther (Cardiovascular diagnosis and therapy)
[2018, 8(1):80-89]

Cited: 0 times

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Congenital complete atrioventricular block with pulmonary hypertension.

Akiko Komori, Mamoru Ayusawa, Masataka Kato, Takahiro Nakamura, Shori Takahashi,

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2017, 59(10):1095-1096]

Cited: 0 times

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Factors affecting N-terminal pro-brain natriuretic peptide elevation in the acute phase of Kawasaki disease.

Daisuke Yanagisawa, Mamoru Ayusawa, Masataka Kato, Hirofumi Watanabe, Akiko Komori, Yuriko Abe, Takahiro Nakamura, Hiroshi Kamiyama, Shori Takahashi,

The aim of this study was to investigate the clinical significance and factors that affect N-terminal pro-brain natriuretic peptide (NT-proBNP) elevation in the acute phase of Kawasaki disease (KD) despite the absence of apparent cardiac complications.The laboratory and echocardiography results of 44 KD patients in the acute and subacute phases ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2016, 58(11):1105-1111]

Cited: 3 times

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Idiopathic pulmonary hemosiderosis complicated by Down syndrome.

Hirofumi Watanabe, Mamoru Ayusawa, Masataka Kato, Ami Chou, Akiko Komori, Yuriko Abe, Masaharu Matsumura, Hiroshi Kamiyama, Hiroyuki Izumi, Shori Takahashi,

We report the case of a 9-year-old girl with Down syndrome (DS) diagnosed with idiopathic pulmonary hemosiderosis (IPH). Although acute pneumonia complicated by hemolytic anemia was suspected, IPH was finally diagnosed on bronchoscopy. Treatment with prednisolone achieved good clinical response. An association between IPH and DS was not able to ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2015, 57(5):1009-1012]

Cited: 1 time

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Efficacy of hemodynamic-based management of tachyarrhythmia after repair of tetralogy of Fallot.

Aya Miyazaki, Heima Sakaguchi, Hideo Ohuchi, Michio Matsuoka, Akiko Komori, Tetsuya Yamamoto, Kenji Yasuda, Kazuhiro Satomi, Takaya Hoashi, Shiro Kamakura, Osamu Yamada,

BACKGROUND:Supraventricular and ventricular tachyarrhythmias (SVT, VT) are major concerns after repair of tetralogy of Fallot (TOF). This study evaluated the impact of comprehensive treatment, including hemodynamic interventions such as surgery, catheter-based intervention and pacemaker implantation (PMI), on tachyarrhythmia in repaired TOF patients. METHODS AND RESULTS:Of 66 repaired TOF patients with ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2012, 76(12):2855-2862]

Cited: 7 times

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The follow-up evaluation of electrocardiogram and arrhythmias in children with fulminant myocarditis.

Rie Ichikawa, Naokata Sumitomo, Akiko Komori, Yuriko Abe, Takahiro Nakamura, Junji Fukuhara, Masaharu Matsumura, Michio Miyashita, Hiroshi Kanamaru, Mamoru Ayusawa, Hideo Mugishima,

BACKGROUND:Fulminant myocarditis involves various serious arrhythmias that sometimes have lethal consequences. The purpose of the present study was to investigate the electrocardiogram findings, arrhythmogenicity and abnormalities of the cardiac conduction system in children with fulminant myocarditis. METHODS AND RESULTS:Between 1999 and 2008, 7 consecutive patients (mean age: 7 years) who ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2011, 75(4):932-938]

Cited: 16 times

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Effects of miglitol, an alpha-glucosidase inhibitor, on glycaemic status and histopathological changes in islets in non-obese, non-insulin-dependent diabetic Goto-Kakizaki rats.

Toshinao Goda, Kazuhito Suruga, Akiko Komori, Sachi Kuranuki, Kazuki Mochizuki, Yumi Makita, Toshihiko Kumazawa,

Miglitol, a 1-deoxynojirimycin derivative, is an alpha-glucosidase inhibitor. In the present study, the effects of acute (single-dose) and chronic (8-week) oral administration of miglitol in Goto-Kakizaki (GK) rats, an animal model of type 2 diabetes, were investigated. Dose-dependent decreases in incremental blood glucose concentrations integrated over a period of 2 ... Read more >>

Br. J. Nutr. (The British journal of nutrition)
[2007, 98(4):702-710]

Cited: 13 times

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