Full Text Journal Articles by
Author Aki Nakamura

Advertisement

Find full text journal articles






A Method Enabling Comprehensive Isolation of Arabidopsis Mutants Exhibiting Unusual Root Mechanical Behavior.

Hiroshi Tojo, Aki Nakamura, Ali Ferjani, Yusuke Kazama, Tomoko Abe, Hidetoshi Iida,

Root penetration into soils is fundamental for land plants to support their own aboveground parts and forage water and nutrients. To elucidate the molecular mechanisms underlying root mechanical penetration, mutants defective in this behavior need to be comprehensively isolated; however, established methods are currently scarce. We herein report a method ... Read more >>

Front Plant Sci (Frontiers in plant science)
[2021, 12:646404]

Cited: 0 times

View full text PDF listing >>



Anti-inflammatory effects of ozenoxacin, a topical quinolone antimicrobial agent.

Keisuke Tabara, Rie Tamura, Aki Nakamura, Sachi Mori, Takamichi Kitano, Koki Fujikawa, Mika Fujikawa, Kazuaki Okamoto, Shoji Kanayama, Hideya Uratsuji, Fumiaki Ikeda, Tatsumi Matsumoto,

Ozenoxacin is a topical quinolone showing potent antimicrobial activities against Gram-negative and Gram-positive bacteria and is widely used for the treatment of inflammatory acne. However, the anti-inflammatory activities of ozenoxacin have not been examined so far. In the present study, we investigated the in vitro and in vivo anti-inflammatory effects ... Read more >>

J Antibiot (Tokyo) (The Journal of antibiotics)
[2020, 73(4):247-254]

Cited: 2 times

View full text PDF listing >>



Advertisement

Anti-inflammatory effect of lanoconazole on 12-O-tetradecanoylphorbol-13-acetate- and 2,4,6-trinitrophenyl chloride-induced skin inflammation in mice.

Aki Nakamura, Hideya Uratsuji, Yoshihito Yamada, Kei Hashimoto, Naoki Nozawa, Tatsumi Matsumoto,

<h4>Background</h4>Lanoconazole (LCZ) is a topical antifungal agent clinically used to treat fungal infections such as tinea pedis. LCZ has not only antifungal effects but also anti-inflammatory effects, which have the potential to provide additional clinical benefits. However, the characteristic features of the inhibitory effects of LCZ on skin inflammation remain ... Read more >>

Mycoses (Mycoses)
[2020, 63(2):189-196]

Cited: 1 time

View full text PDF listing >>



Chaperonin TRiC/CCT supports mitotic exit and entry into endocycle in Drosophila.

Yuya Ohhara, Aki Nakamura, Yuki Kato, Kimiko Yamakawa-Kobayashi,

Endocycle is a commonly observed cell cycle variant through which cells undergo repeated rounds of genome DNA replication without mitosis. Endocycling cells arise from mitotic cells through a switch of the cell cycle mode, called the mitotic-to-endocycle switch (MES), to initiate cell growth and terminal differentiation. However, the underlying regulatory ... Read more >>

PLoS Genet (PLoS genetics)
[2019, 15(4):e1008121]

Cited: 2 times

View full text PDF listing >>



Ca2+-permeable mechanosensitive channels MCA1 and MCA2 mediate cold-induced cytosolic Ca2+ increase and cold tolerance in Arabidopsis.

Kendo Mori, Na Renhu, Maho Naito, Aki Nakamura, Hayato Shiba, Tsuyoshi Yamamoto, Takuya Suzaki, Hidetoshi Iida, Kenji Miura,

Cold shock triggers an immediate rise in the cytosolic free calcium concentration ([Ca2+]cyt) in Arabidopsis thaliana and this cold-induced elevation of [Ca2+]cyt is inhibited by lanthanum or EGTA. It is suggested that intracellular calcium mainly contributes to the cold-induced [Ca2+]cyt response by entering into the cytosol. Two calcium-permeable mechanosensitive channels, ... Read more >>

Sci Rep (Scientific reports)
[2018, 8(1):550]

Cited: 18 times

View full text PDF listing >>



Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice.

Yoshihito Yamada, Yuhki Ueda, Aki Nakamura, Shoji Kanayama, Rie Tamura, Kei Hashimoto, Tatsumi Matsumoto, Ritsuko Ishii,

Atopic dermatitis (AD)-like dermatitis can be induced by repeated topical application of an ointment containing Dermatophagoides farinae body (Dfb) extract in NC/Nga mice. This AD-like murine model also exhibits a biphasic increase in the number of scratching behaviour after topical application of Dfb ointment. In this study, we investigated the ... Read more >>

Exp Dermatol (Experimental dermatology)
[2018, 27(4):418-426]

Cited: 0 times

View full text PDF listing >>



Biphasic increase in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice.

Yoshihito Yamada, Yuhki Ueda, Aki Nakamura, Shoji Kanayama, Rie Tamura, Kei Hashimoto, Hiroko Kido, Tatsumi Matsumoto, Ritsuko Ishii,

Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by severe itching and eczematous lesion. In this study, we applied an ointment containing Dermatophagoides farinae body (Dfb) extract repeatedly on the dorsal skin of NC/Nga mice with barrier disruption to investigate the characteristics of this murine model of human ... Read more >>

Exp Dermatol (Experimental dermatology)
[2016, 25(8):611-617]

Cited: 6 times

View full text PDF listing >>



Anti-inflammatory activity of lanoconazole, a topical antifungal agent.

Hideya Uratsuji, Aki Nakamura, Yoshihito Yamada, Kei Hashimoto, Tatsumi Matsumoto, Fumiaki Ikeda, Ritsuko Ishii,

Topical antifungal agents which have anti-inflammatory effects have the potential to provide additional clinical benefits. Therefore, an anti-inflammatory activity of lanoconazole (LCZ), a topical antifungal agent, was investigated against in vitro and in vivo models of inflammation. The release of interleukin-8 (IL-8) from human epidermal keratinocytes stimulated by the addition ... Read more >>

Mycoses (Mycoses)
[2015, 58(4):197-202]

Cited: 2 times

View full text PDF listing >>



Association of short sleep duration with impaired glucose tolerance or diabetes mellitus.

Sayuri Katano, Yasuyuki Nakamura, Aki Nakamura, Yoshitaka Murakami, Taichiro Tanaka, Toru Takebayashi, Akira Okayama, Katsuyuki Miura, Tomonori Okamura, Hirotsugu Ueshima, ,

<h4>Unlabelled</h4>Aims/Introduction:  To examine the cross-sectional relationship between sleep duration and impaired glucose tolerance (IGT), including diabetes mellitus (DM), we analyzed a large-scale healthy workers database in Japan.<h4>Materials and methods</h4>  We examined the baseline database of 4143 participants (3415 men and 728 women) aged 19-69 years. Sleep duration of participants was categorized ... Read more >>

J Diabetes Investig (Journal of diabetes investigation)
[2011, 2(5):366-372]

Cited: 4 times

View full text PDF listing >>



Pioglitazone-induced body weight gain is prevented by combined administration with the lipoprotein lipase activator NO-1886.

Masataka Kusunoki, Kazuhiko Tsutsumi, Daisuke Sato, Aki Nakamura, Satoshi Habu, Yuichi Mori, Munehiko Morishita, Takayuki Yonemoto, Tetsuro Miyata, Yutaka Nakaya, Takao Nakamura,

Pioglitazone improves insulin resistance in diabetics but often causes body weight gain. The lipoprotein lipase activator NO-1886 has been shown to exert both anti-obesity and anti-insulin-resistance effects. In this study, we investigated the effect of the combined administration of pioglitazone with NO-1886 (pioglitazone+NO-1886) in preventing body weight gain in insulin-resistant, ... Read more >>

Eur J Pharmacol (European journal of pharmacology)
[2011, 668(3):486-491]

Cited: 5 times

View full text PDF listing >>



Relationship between health-related quality of life and clustering of metabolic syndrome diagnostic components.

Sayuri Katano, Yasuyuki Nakamura, Aki Nakamura, Yoshimi Suzukamo, Yoshitaka Murakami, Taichiro Tanaka, Akira Okayama, Katsuyuki Miura, Tomonori Okamura, Shunichi Fukuhara, Hirotsugu Ueshima, ,

<h4>Purpose</h4>To examine the association of the number of metabolic syndrome diagnostic components (MetS-DC) with health-related quality of life (HR-QOL).<h4>Methods</h4>We examined the baseline data from 4,480 healthy workers in Japan (3,668 men and 812 women) aged 19-69 years. We assessed HR-QOL based on scores for five scales of the SF-36. We ... Read more >>

Qual Life Res (Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation)
[2012, 21(7):1165-1170]

Cited: 10 times

View full text PDF listing >>



Relationship between sleep duration and clustering of metabolic syndrome diagnostic components.

Sayuri Katano, Yasuyuki Nakamura, Aki Nakamura, Yoshitaka Murakami, Taichiro Tanaka, Toru Takebayashi, Akira Okayama, Katsuyuki Miura, Tomonori Okamura, Hirotsugu Ueshima, ,

<h4>Objective</h4>To examine the relation between sleep duration and metabolic syndrome (MetS).<h4>Methods</h4>We examined the baseline data from 4356 healthy workers (3556 men and 800 women) aged 19-69 years. The physical activity of each participant was classified according to the International Physical Activity Questionnaire (IPAQ). We defined four components of MetS diagnostic ... Read more >>

Diabetes Metab Syndr Obes (Diabetes, metabolic syndrome and obesity : targets and therapy)
[2011, 4:119-125]

Cited: 18 times

View full text PDF listing >>



Relationship among physical activity, smoking, drinking and clustering of the metabolic syndrome diagnostic components.

Sayuri Katano, Yasuyuki Nakamura, Aki Nakamura, Yoshitaka Murakami, Taichiro Tanaka, Hideaki Nakagawa, Toru Takebayashi, Hiroshi Yamato, Akira Okayama, Katsuyuki Miura, Tomonori Okamura, Hirotsugu Ueshima, ,

<h4>Aim</h4>To examine the relation between lifestyle and the number of metabolic syndrome (MetS) diagnostic components in a general population, and to find a means of preventing the development of MetS components.<h4>Methods</h4>We examined baseline data from 3,365 participants (2,714 men and 651 women) aged 19 to 69 years who underwent a ... Read more >>

J Atheroscler Thromb (Journal of atherosclerosis and thrombosis)
[2010, 17(6):644-650]

Cited: 23 times

View full text PDF listing >>



Enhancement of reaction efficiency by functionalized alcohols on gold(I)-catalyzed intermolecular hydroalkoxylation of unactivated olefins.

Toshifumi Hirai, Akiyuki Hamasaki, Aki Nakamura, Makoto Tokunaga,

Intermolecular hydroalkoxylation of unactivated olefins catalyzed by the combination of gold(I) and electron deficient phosphine ligands has been developed. Although pairings of unactivated olefins and common aliphatic alcohols gave unsatisfactory results in gold catalyzed hydroalkoxylations, the use of alcohol substrates bearing coordination functionalities such as halogen or alkoxy groups showed ... Read more >>

Org Lett (Organic letters)
[2009, 11(23):5510-5513]

Cited: 9 times

View full text PDF listing >>



[A successful case of advanced nasal adenocarcinoma treated with tumor dormancy therapy with S -1 alone].

Hiroyoshi Iguchi, Taichi Uyama, Akimori Kanazawa, Hisao Amatsu, Hideo Yamane, Makoto Kusuki, Aki Nakamura,

We report a 65-year-old female case of low-grade non-intestinal type adenocarcinoma of the nasal cavity with bilateral metastases to the cervical lymph nodes(T3N2cM0: Stage IV A). Chemoradiotherapy administered as first-line therapy yielded only a partial response in the primary tumor and metastatic lesions, and subsequent chemotherapy with S-1(at a dose ... Read more >>

Gan To Kagaku Ryoho (Gan to kagaku ryoho. Cancer & chemotherapy)
[2008, 35(13):2389-2391]

Cited: 0 times

View full text PDF listing >>



NO-1886, a lipoprotein lipase activator, attenuates contraction of rat intestinal ring preparations.

Qishisan Wu, Nagakatsu Harada, Aki Nakamura, Masaki Yoshida, Kazuaki Mawatari, Atsushi Hattori, Qinkai Li, Takaaki Shimohata, Yinhua, Xin Lian, Masayuki Nakano, Toshio Hosaka, Akira Takahashi, Yutaka Nakaya,

Various intestinal symptoms or diseases are closely associated with intestinal motility, which may be altered by metabolic disturbances associated with diabetes and obesity. It is therefore important that drugs used in the treatment of metabolic disorders should not have any adverse effects on the intestine. In the present study, we ... Read more >>

J Med Invest (The journal of medical investigation : JMI)
[2008, 55(1-2):61-70]

Cited: 2 times

View full text PDF listing >>



Identification of cis-acting promoter sequences required for expression of the glycerol-3-phosphate acyltransferase 1 gene in mice.

Masaki Yoshida, Nagakatsu Harada, Hironori Yamamoto, Yutaka Taketani, Tadahiko Nakagawa, Yunjie Yin, Atsushi Hattori, Tomoe Zenitani, Sayuri Hara, Haruka Yonemoto, Aki Nakamura, Masayuki Nakano, Kazuaki Mawatari, Kiyoshi Teshigawara, Hidekazu Arai, Toshio Hosaka, Akira Takahashi, Katsuhiko Yoshimoto, Yutaka Nakaya,

Glycerol-3-phosphate acyltransferase 1 (GPAT1) is a rate limiting enzyme in de novo glycerophospholipid synthesis. The murine GPAT1 promoter sequence (the "classical" sequence) was reported previously. However, the organization of this DNA sequence does not fully match the mouse genome sequences on NCBI/GenBank. Here we have identified net cis-acting promoter sequences ... Read more >>

Biochim Biophys Acta (Biochimica et biophysica acta)
[2009, 1791(1):39-52]

Cited: 6 times

View full text PDF listing >>



Laryngeal myxoma.

Aki Nakamura, Hiroyoshi Iguchi, Makoto Kusuki, Hideo Yamane, Miki Matsuda, Shigeto Osako,

Myxoma is a rare benign tumor, and occurs most commonly in the mandible and maxilla in the head and neck region. Myxoma of the larynx is extremely rare and is frequently misdiagnosed as a vocal polyp. We present the first female case of myxoma on a vocal cord and review ... Read more >>

Acta Otolaryngol (Acta oto-laryngologica)
[2008, 128(1):110-112]

Cited: 6 times

View full text PDF listing >>



Insulin activates ATP-sensitive potassium channels via phosphatidylinositol 3-kinase in cultured vascular smooth muscle cells.

Sonoko Yasui, Kazuaki Mawatari, Takashi Kawano, Ran Morizumi, Akiko Hamamoto, Hiroko Furukawa, Kei Koyama, Aki Nakamura, Atsushi Hattori, Masayuki Nakano, Nagakatsu Harada, Toshio Hosaka, Akira Takahashi, Shuzo Oshita, Yutaka Nakaya,

The effects of insulin on the vasculature are significant because insulin resistance is associated with hypertension. To increase the understanding of the effects of insulin on the vasculature, we analyzed changes in potassium ion transport in cultured vascular smooth muscle cells (VSMCs). Using the potential-sensitive fluorescence dye bis-(1,3-dibutylbarbituric acid)trimethine oxonol ... Read more >>

J Vasc Res (Journal of vascular research)
[2008, 45(3):233-243]

Cited: 11 times

View full text PDF listing >>



A three-year-follow-up study on the change in physical and mental functions of the aged by the level ofADL. Evaluation of data from the Japanese elderly care insurance certification of long-term care need.

Aki Nakamura, Yosuke Ooe, Yuko Ohno, Takashi Nakamura,

Using the value in which the physical and mental condition of elderly persons was converted into the amount of care required time, this paper estimates the average change of physical and mental functions according to the subject's sex and independence level of primary ADL (Activities of Daily Living) over a ... Read more >>

Jpn Hosp (Japan-hospitals : the journal of the Japan Hospital Association)
[2007, (26):41-52]

Cited: 0 times

View full text PDF listing >>



NO-1886, a lipoprotein lipase activator, attenuates vascular smooth muscle contraction in rat aorta.

Aki Nakamura, Nagakatsu Harada, Akira Takahashi, Kazuaki Mawatari, Masayuki Nakano, Kazuhiko Tsutsumi, Yutaka Nakaya,

The chemical compound [4-(4-bromo-2-cyano-phenylcarbamoyl)-benzyl]-phosphonic acid diethyl ester (NO-1886) is a lipoprotein lipase activator having beneficial effects on both diabetes control and the cardiovascular system. Preventing accumulation of lipids in the cell wall, in addition to improving insulin actions on vasculature, may indirectly contribute to the reducing effect of NO-1886 on ... Read more >>

Eur J Pharmacol (European journal of pharmacology)
[2007, 554(2-3):183-190]

Cited: 3 times

View full text PDF listing >>



Inhibitory effects of alendronate on cholinergic responses in rat lower esophageal sphincter.

Tadayoshi Takeuchi, Aki Nakamura, Hidemitsu Nakajima, Yasu-Taka Azuma, Fumiaki Hata,

Alendronate is a potent inhibitor of osteoclast-mediated bone resorption, but its use results in serious esophageal damage. In order to clarify the latter, we examined the effects of alendronate on electrical field stimulation-induced responses in the rat lower esophageal sphincter. Electrical field stimulation induced atropine-sensitive contraction. Alendronate inhibited electrical field ... Read more >>

Eur J Pharmacol (European journal of pharmacology)
[2006, 537(1-3):155-159]

Cited: 1 time

View full text PDF listing >>



Transmucosal coil migration after endovascular management for carotid artery pseudoaneurysm: a late complication.

Hiroyoshi Iguchi, Masahiro Takayama, Makoto Kusuki, Aki Nakamura, Akimori Kanazawa, Kazutaka Hachiya, Hideo Yamane,

Acta Otolaryngol (Acta oto-laryngologica)
[2007, 127(4):447-448]

Cited: 6 times

View full text PDF listing >>



Intramasseteric schwannoma in a child.

Aki Nakamura, Hiroyoshi Iguchi, Makoto Kusuki, Takashi Zushi, Hideo Yamane, Kenichi Wakasa,

Schwannoma arising in muscle is rare. We treated a very unusual case of schwannoma originating in the masseter muscle in a 12-year-old boy, who presented with a 1-year history of a painless left cheek mass. CT and MRI revealed that the mass existed in the masseter muscle. It was extirpated ... Read more >>

Auris Nasus Larynx (Auris, nasus, larynx)
[2006, 33(3):347-350]

Cited: 9 times

View full text PDF listing >>



Carotid artery pseudoaneurysm as a rare sequela of surgery for laryngeal cancer.

Hiroyoshi Iguchi, Masahiro Takayama, Makoto Kusuki, Aki Nakamura, Akimori Kanazawa, Kazutaka Hachiya, Hideo Yamane,

Formation of carotid artery pseudoaneurysm is uncommon after intensive treatment for head and neck cancer. We encountered a case of postoperative formation of pseudoaneurysm at the left carotid bifurcation in a diabetic man. The risk factors for carotid artery pseudoaneurysm in the patient included diabetes mellitus, previous radiotherapy to the ... Read more >>

Acta Otolaryngol (Acta oto-laryngologica)
[2006, 126(5):557-560]

Cited: 4 times

View full text PDF listing >>



Advertisement


Disclaimer

1.1113 s