Full Text Journal Articles by
Author Akanksha Jain

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DNA fingerprinting of cultivated and wild genotypes of Curcuma species from agroclimatic regions of Chhattisgarh

Akanksha Jain, Parag Jain,

Abstract In the present study we had tried to investigate different genotypes of Curcuma isolated from different agroclimatic zones of Chattisgarh based on molecular fingerprinting as they contain varying range of Curcumin. Genetic fingerprints of 25 genotypes of Curcuma caesia, Curcuma longa and Curcuma aromatica by using 13 and 11 ... Read more >>

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COVID-19 Pandemic - Are We Heading From Health Crisis Towards An Unprecedented Nutrition Crisis?

Yogesh Kumar, Akanksha Jain,

Curr Top Med Chem (Current topics in medicinal chemistry)
[2020, :]

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Antioxidant Evaluation and Chemo-Profiling of Non-conventional Curcuma Species as Conservation of Drug Targeting Molecule

Akanksha Jain, Parag Jain,

Abstract The objective of the present study was to determine and compare antioxidant activities of different species of Curcuma i.e. Curcuma longa , Curcuma caesia and Curcuma aromatic and their chemoprofiling for conservation of highest yield plants. The functional group analysis of the plants extract were determined by FTIR and ... Read more >>

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Effect of scaling and root planing as monotherapy on glycemic control in patients of Type 2 diabetes with chronic periodontitis: A systematic review and meta-analysis.

Akanksha Jain, Jyoti Gupta, Dipika Bansal, Shaveta Sood, Shipra Gupta, Ashish Jain,

Background:There is enough evidence, which suggests that nonsurgical periodontal therapy (NSPT) improved the glycemic control in patients of Type 2 diabetes mellitus (T2DM) with chronic periodontitis (CP). This meta-analysis is aimed to explore the effect of NSPT, exclusively scaling and root planing (SRP) as monotherapy on glycemic control and periodontal ... Read more >>

J Indian Soc Periodontol (Journal of Indian Society of Periodontology)
[2019, 23(4):303-310]

Cited: 1 time

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Incidence, Risk Factors, and Outcome of Cardiac Arrhythmia Postcardiac Surgery in Children.

Akanksha Jain, Shahzad Alam, S Kiran Viralam, Tanzila Sharique, Saurabh Kapoor,

Objective:To study the incidence of postoperative cardiac arrhythmias in children undergoing cardiac surgery and to evaluate the risk factors and outcome of these patients. Materials and Methods:This retrospective observational study was conducted in the cardiac pediatric intensive care unit and included children <18 years of age. Children were monitored in ... Read more >>

Heart Views (Heart views : the official journal of the Gulf Heart Association)
[2019, 20(2):47-52]

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Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects.

Stefan Münster, Akanksha Jain, Alexander Mietke, Anastasios Pavlopoulos, Stephan W Grill, Pavel Tomancak,

During gastrulation, physical forces reshape the simple embryonic tissue to form the complex body plans of multicellular organisms1. These forces often cause large-scale asymmetric movements of the embryonic tissue2,3. In many embryos, the gastrulating tissue is surrounded by a rigid protective shell4. Although it is well-recognized that gastrulation movements depend ... Read more >>

Nature (Nature)
[2019, 568(7752):395-399]

Cited: 2 times

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Publisher Correction: Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects.

Stefan Münster, Akanksha Jain, Alexander Mietke, Anastasios Pavlopoulos, Stephan W Grill, Pavel Tomancak,

In this Letter, the sentence starting: 'For instance, Tribolium and Drosophila inflated are direct targets of the mesoderm…' has been corrected online; see accompanying Amendment. ... Read more >>

Nature (Nature)
[2019, 568(7753):E14]

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Content-aware image restoration: pushing the limits of fluorescence microscopy.

Martin Weigert, Uwe Schmidt, Tobias Boothe, Andreas Müller, Alexandr Dibrov, Akanksha Jain, Benjamin Wilhelm, Deborah Schmidt, Coleman Broaddus, Siân Culley, Mauricio Rocha-Martins, Fabián Segovia-Miranda, Caren Norden, Ricardo Henriques, Marino Zerial, Michele Solimena, Jochen Rink, Pavel Tomancak, Loic Royer, Florian Jug, Eugene W Myers,

Fluorescence microscopy is a key driver of discoveries in the life sciences, with observable phenomena being limited by the optics of the microscope, the chemistry of the fluorophores, and the maximum photon exposure tolerated by the sample. These limits necessitate trade-offs between imaging speed, spatial resolution, light exposure, and imaging ... Read more >>

Nat. Methods (Nature methods)
[2018, 15(12):1090-1097]

Cited: 11 times

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Understanding Patient Preferences and Unmet Needs in Non-alcoholic Steatohepatitis (NASH): Insights from a Qualitative Online Bulletin Board Study.

Nigel S Cook, Sarthak H Nagar, Akanksha Jain, Maria-Magdalena Balp, Miriam Mayländer, Olivia Weiss, Satabdi Chatterjee,

INTRODUCTION:The aim of this work was to understand how patients with non-alcoholic steatohepatitis (NASH) perceive their disease, unmet needs, and expectations regarding future treatment through online bulletin board (OBB) qualitative research. METHODS:OBB is an asynchronous online qualitative market research tool that provides an open forum for interactive discussion among participants. ... Read more >>

Adv Ther (Advances in therapy)
[2019, 36(2):478-491]

Cited: 3 times

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Predictors and outcome of early extubation in infants postcardiac surgery: A single-center observational study.

Shahzad Alam, Akunuri Shalini, Rajesh G Hegde, Rufaida Mazahir, Akanksha Jain,

Objective:The objective of the current study was to evaluate the timing of first extubation and compare the outcome of patient extubated early with others; we also evaluated the predictors of early extubation in our cohort. Materials and Methods:This prospective cohort study included children <1 year of age undergoing surgery for ... Read more >>

Ann Card Anaesth (Annals of cardiac anaesthesia)
[2018, 21(4):402-406]

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Integrin-mediated attachment of the blastoderm to the vitelline envelope impacts gastrulation of insects

Stefan Münster, Akanksha Jain, Alexander Mietke, Anastasios Pavlopoulos, Stephan Grill, Pavel Tomancak,

Abstract During gastrulation, physical forces reshape the simple embryonic tissue to form a complex body plan of multicellular organisms 1 . These forces often cause large-scale asymmetric movements of the embryonic tissue 2,3 . In many embryos, the tissue undergoing gastrulation movements is surrounded by a rigid protective shell 4,5 ... Read more >>

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Synthesis and evaluation of 68Ga labeled palmitic acid for cardiac metabolic imaging.

Akanksha Jain, Anupam Mathur, Usha Pandey, Haladhar Dev Sarma, Ashutosh Dash,

This work evaluates the potential of a 68Ga labeled long chain 16C fatty acid for cardiac metabolic imaging. For radiolabeling with 68Ga, hexadecanedioic acid was coupled with the chelator p-NH2-Bn-NOTA. Under the optimized conditions, NOTA-hexadecanoic acid could be radiolabeled with 68Ga in ≥95% yields. In biodistribution studies carried out in ... Read more >>

Appl Radiat Isot (Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine)
[2018, 140:35-40]

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Vasoactive-ventilation-renal score in predicting outcome postcardiac surgery in children.

Shahzad Alam, Shalini Akunuri, Akanksha Jain, Rufaida Mazahir, Rajesh Hegde,

The objective of this study was to evaluate vasoactive-ventilation-renal (VVR) score to predict outcome postcardiac surgery in children and establish the time at which the score is best to predict outcome.This prospective cohort included children ≤18 years recovering from cardiac surgery for congenital heart disease. Data were collected from the ... Read more >>

Int J Crit Illn Inj Sci (International journal of critical illness and injury science)
[2018, 8(3):143-148]

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A Systematic Comparative Evaluation of 68Ga-Labeled RGD Peptides Conjugated with Different Chelators.

Akanksha Jain, Sudipta Chakraborty, H D Sarma, Ashutosh Dash,

Purpose:The present paper reports a systematic study on the effect of bifunctional chelators (BFC) namely, NOTA, DOTA, and DTPA, on the radiochemical formulation, in vitro stability, and in vivo biological properties of 68Ga-labeled RGD peptide derivatives. Methods:The three RGD conjugates namely, NOTA-Bn-E-[c(RGDfk)]2, DOTA-Bn-E-[c(RGDfk)]2, and DTPA-Bn-E-[c(RGDfk)]2 were radiolabeled with 68Ga and ... Read more >>

Nucl Med Mol Imaging (Nuclear medicine and molecular imaging)
[2018, 52(2):125-134]

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A 26-year-old man with dyspnea and chest pain.

Saurabh Mittal, Akanksha Jain, Sudheer Arava, Vijay Hadda, Anant Mohan, Randeep Guleria, Karan Madan,

A 26-year-old smoker male presented with a history of sudden onset dyspnea and right-sided chest pain. Chest radiograph revealed large right-sided pneumothorax which was managed with tube thoracostomy. High-resolution computed tomography thorax revealed multiple lung cysts, and for a definite diagnosis, a video-assisted thoracoscopic surgery-guided lung biopsy was performed followed ... Read more >>

Lung India (Lung India : official organ of Indian Chest Society)
[2017, 34(6):562-566]

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Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy

Martin Weigert, Uwe Schmidt, Tobias Boothe, Andreas Müller, Alexandr Dibrov, Akanksha Jain, Benjamin Wilhelm, Deborah Schmidt, Coleman Broaddus, Siân Culley, Mauricio Rocha-Martins, Fabián Segovia-Miranda, Caren Norden, Ricardo Henriques, Marino Zerial, Michele Solimena, Jochen Rink, Pavel Tomancak, Loic Royer, Florian Jug, Eugene Myers,

Fluorescence microscopy is a key driver of discoveries in the life-sciences, with observable phenomena being limited by the optics of the microscope, the chemistry of the fluorophores, and the maximum photon exposure tolerated by the sample. These limits necessitate trade-offs between imaging speed, spatial resolution, light exposure, and imaging depth. ... Read more >>

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68Ga labeled Erlotinib: A novel PET probe for imaging EGFR over-expressing tumors.

Akanksha Jain, Mythili Kameswaran, Usha Pandey, Kumar Prabhash, Haladhar Dev Sarma, Ashutosh Dash,

Molecular imaging using radiolabeled Tyrosine Kinase Inhibitors (TKI) is a promising strategy for detection and staging of EGFR-positive cancers. A novel analogue of one such TKI, Erlotinib has been developed for PET imaging by derivatizing the parent Erlotinib molecule for conjugation with the bifunctional chelator p-SCN-Bn-NOTA towards radiolabeling with 68Ga. ... Read more >>

Bioorg. Med. Chem. Lett. (Bioorganic & medicinal chemistry letters)
[2017, 27(19):4552-4557]

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Chondroid syringoma with extensive cystic change and focal syringometaplasia: A rare histomorphological finding.

Akanksha Jain, Sudheer Arava,

Indian J Pathol Microbiol (Indian journal of pathology & microbiology)
[2018, 61(1):143-144]

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Tracheobronchopathia osteochondroplastica following laryngeal tuberculosis.

Saurabh Mittal, Akanksha Jain, Sudheer Arava, Randeep Guleria, Karan Madan,

Lung India (Lung India : official organ of Indian Chest Society)
[2017, 34(5):483-485]

Cited: 1 time

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Effect of phytosanitary irradiation on the postharvest quality of Seedless Kishu mandarins (Citrus kinokuni mukakukishu).

José de Jesús Ornelas-Paz, María Belén Meza, David Obenland, Karina Rodríguez Friscia, Akanksha Jain, Shantaè Thornton, Anuradha Prakash,

Transnational trade of 'Seedless Kishu' mandarins (Citrus kinokuni mukakukishu) would require them to be subjected to a suitable phytosanitary treatment. Irradiation is used as an effective treatment for many fruit, but the effect on quality of kishu mandarins is unknown. 'Seedless Kishu' mandarins were treated with gamma irradiation (150, 400, ... Read more >>

Food Chem (Food chemistry)
[2017, 230:712-720]

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Coexistence of Both Bronchogenic and Esophageal Duplication Cyst in a Single Mass: An Interesting Coincidence.

Akanksha Jain, Shilpi Agarwal, Anamika Kashyap, Anu Beniwal,

J Indian Assoc Pediatr Surg (Journal of Indian Association of Pediatric Surgeons)
[2017, 22(3):193-195]

Cited: 0 times

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The C-terminal tails of heterotrimeric kinesin-2 motor subunits directly bind to α-tubulin1: Possible implications for cilia-specific tubulin entry.

Mukul Girotra, Shalini Srivastava, Anuttama Kulkarni, Ayan Barbora, Kratika Bobra, Debnath Ghosal, Pavithra Devan, Amol Aher, Akanksha Jain, Dulal Panda, Krishanu Ray,

The assembly of microtubule-based cytoskeleton propels the cilia and flagella growth. Previous studies have indicated that the kinesin-2 family motors transport tubulin into the cilia through intraflagellar transport. Here, we report a direct interaction between the C-terminal tail fragments of heterotrimeric kinesin-2 and α-tubulin1 isoforms in vitro. Blot overlay screen, ... Read more >>

Traffic (Traffic (Copenhagen, Denmark))
[2017, 18(2):123-133]

Cited: 4 times

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68Ga labeled fatty acids for cardiac metabolic imaging: Influence of different bifunctional chelators.

Akanksha Jain, Anupam Mathur, Usha Pandey, Haladhar Dev Sarma, Ashutosh Dash,

Development of 68Ga labeled fatty acids is of immense interest due to the availability of 68Ga through a generator and its superiority over SPECT based tracers in carrying out dynamic imaging on a PET scanner. Our present work explores the influence of different chelators on the cardiac uptake and pharmacokinetics ... Read more >>

Bioorg. Med. Chem. Lett. (Bioorganic & medicinal chemistry letters)
[2016, 26(23):5785-5791]

Cited: 2 times

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Synthesis and evaluation of a (68)Ga labeled folic acid derivative for targeting folate receptors.

Akanksha Jain, Anupam Mathur, Usha Pandey, Jyotsna Bhatt, Archana Mukherjee, Ramu Ram, Haladhar Dev Sarma, Ashutosh Dash,

Present work evaluates the potential of a newly synthesized (68)Ga-NOTA-folic acid conjugate for PET imaging of tumors over-expressing folate receptors (FRs). NOTA-folic acid conjugate was synthesized and characterized. It was radiolabeled with (68)Ga in ≥ 95% radiolabeling yields. In vitro cell binding studies showed a maximum cell uptake of 1.7±0.4% ... Read more >>

Appl Radiat Isot (Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine)
[2016, 116:77-84]

Cited: 1 time

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Delayed diagnosis of endobronchial mucoepidermoid carcinoma in a 29-year-old male.

Akanksha Jain, Neha Kawatra Madan, Sudheer Arava, Durgatosh Pandey, Karan Madan,

Mucoepidermoid carcinoma (MEC) is an uncommon primary lung tumor. It usually involves large airways and presents clinically and radiologically with nonspecific features. Because of nonspecific presentation diagnosis is frequently delayed. We report the case of a 29-year-old male patient wherein a clinico-radiological consideration of tuberculosis (TB) led to a prolonged ... Read more >>

Lung India (Lung India : official organ of Indian Chest Society)
[2016, 33(3):323-325]

Cited: 0 times

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