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Author Ahmet Soysal

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Impact of the 13-valent pneumococcal conjugate vaccine on the incidences of community-acquired pneumonia and pneumonia-related hospitalizations in children ≤5 years after its implementation into the national immunization program of Turkey.

Erdem Gönüllü, Ahmet Soysal, Ismail Yıldız, Gökhan Aydemir, Turan Tunç, Metin Karaböcüoğlu,

The aim of the study was to investigate changes in the incidences of community-acquired pneumonia (CAP) and CAP-related hospitalizations following introduction of 13-valent pneumococcal conjugate vaccine (PCV13) in children ≤5 years of age into the national immunization programme (NIP) of Turkey. PCV7 was included in the NIP of Turkey in November ... Read more >>

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2020, :1-5]

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The impact of vitamin B12 deficiency on infant gut microbiota.

Perran Boran, Hatice Ezgi Baris, Eda Kepenekli, Can Erzik, Ahmet Soysal, Duy M Dinh,

Although physiologic and neurologic consequences of micronutrient deficiencies have been addressed extensively, less is known about their impact on developing gut microbiota. Vitamin B12 deficiency is a common micronutrient deficiency in infants. We aimed to analyze the gut microbial composition of exclusively breastfed infants aged between 4 and 6 months ... Read more >>

Eur. J. Pediatr. (European journal of pediatrics)
[2020, 179(3):385-393]

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Knowledge and acceptance of influenza and pertussis vaccinations among pregnant women of low socioeconomic status in Turkey.

Nurhayat Yakut, Sunullah Soysal, Ahmet Soysal, Mustafa Bakir,

Pregnant women and infants are at relatively high risk for influenza- and pertussis-related morbidity and mortality. Vaccination is the most important prevention strategy for both diseases. We evaluated knowledge and acceptance of influenza and pertussis vaccinations among pregnant women. We performed a cross-sectional survey of 465 pregnant women receiving prenatal ... Read more >>

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2020, 16(5):1101-1108]

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Fever-Associated Supraventricular Tachycardia after 4CMenB Vaccination in an Infant.

Erdem Gönüllü, Burcu Topçu, Naci Öner, Ahmet Soysal, Metin Karaböcüoğlu,

Meningococcal serogroup B vaccine 4CMenB (Bexsero) is a new four-component protein vaccine developed to prevent Neisseria meningitidis serogroup B infections. Case. We report a girl with fever and supraventricular tachycardia (SVT) 6-8 hours after the second dose of 4CMenB. SVT was unresponsive to the first dose of adenosine but terminated ... Read more >>

Case Rep Pediatr (Case reports in pediatrics)
[2019, 2019:4591964]

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Impact of the 13-valent pneumococcal conjugate vaccine on the incidences of acute otitis media, recurrent otitis media and tympanostomy tube insertion in children after its implementation into the national immunization program in Turkey.

Ahmet Soysal, Erdem Gönüllü, Ismail Yıldız, Gökhan Aydemir, Turan Tunç, Yezdan Fırat, Burak Erdamar, Metin Karaböcüoğlu,

The aim of this study was to investigate changes in the incidences of acute otitis media (AOM), recurrent AOM (rAOM) and tympanostomy tube (TT) insertion in children following the introduction of 13-valent pneumococcal conjugate vaccine (PCV13) into the national immunization program (NIP) of Turkey in April 2011. National coverage for ... Read more >>

Hum Vaccin Immunother (Human vaccines & immunotherapeutics)
[2020, 16(2):445-451]

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Influenza A (H1N1)-associated severe complications; hemolytic uremic syndrome, myocarditis, acute necrotizing encephalopathy.

Sevliya Öcal Demir, Serkan Atıcı, Eda Kepenekli Kadayifci, Gülşen Akkoç, Nurhayat Yakut, Feyza İnceköy Girgin, Nilüfer Yalındağ Öztürk, Ahmet Soysal,

Influenza is a generally self-limited infection agent that only rarely causes severe complications. To increase awareness about its serious complications, we report three cases of influenza A (H1N1) infection complicated with hemolytic uremic syndrome, myocarditis and acute necrotizing encephalopathy. In all three cases, nasopharyngeal samples confirmed influenza A (H1N1) infection ... Read more >>

J Infect Dev Ctries (Journal of infection in developing countries)
[2019, 13(1):83-86]

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Socioeconomic factors associated with tobacco smoking in Turkey: a cross-sectional, population-based study.

Ceyda Sahan, Turkan Gunay, Hatice Simsek, Ahmet Soysal, Gul Ergor,

Background:Gender and lower socioeconomic status are associated with smoking. Aims:This study aimed to determine the association between socioeconomic factors and cigarette tobacco smoking in Balcova, Izmir, Turkey, with a focus on gender differences. Methods:The study population was all men and women (36 187) aged over 30 years living in Balcova ... Read more >>

East. Mediterr. Health J. (Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit)
[2018, 24(8):705-713]

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Prevalence of Nasopharyngeal Carriage, Serotype Distribution, and Antimicrobial Resistance of Streptococcus pneumoniae among Children with Chronic Diseases.

Serdar Pekuz, Ahmet Soysal, Gulsen Akkoc, Serkan Atıcı, Nurhayat Yakut, Gulsen Altınkanat Gelmez, Eda Kepenekli Kadayifci, Deniz Güneser, Sevliya Ocal Demir, Guner Söyletir, Mustafa Bakır,

The aim of this study was to evaluate the prevalence of nasopharyngeal (NP) carriage and the serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in children with chronic diseases, which predisposes them to invasive pneumococcal disease in comparison with that in healthy children. A cross-sectional prevalence study was performed between ... Read more >>

Jpn. J. Infect. Dis. (Japanese journal of infectious diseases)
[2019, 72(1):7-13]

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Ventriculoperitoneal shunt infections and re-infections in children: a multicentre retrospective study.

Nurhayat Yakut, Ahmet Soysal, Eda Kepenekli Kadayifci, Nazan Dalgic, Dilek Yılmaz Ciftdogan, Ayse Karaaslan, Gulsen Akkoc, Sevliya Ocal Demir, Eren Cagan, Ezgi Celikboya, Ali Kanik, Adnan Dagcinar, Adem Yilmaz, Fusun Ozer, Mahmut Camlar, Ozden Turel, Mustafa Bakir,

PURPOSE:Ventriculoperitoneal shunt (VPS) is the most common treatment modality for hydrocephalus. However, VPS infection is a common and serious complication with high rates of mortality and morbidity. The objective of this study was to investigate causative agents and the management of VPS infections and to identify risk factors for re-infection ... Read more >>

Br J Neurosurg (British journal of neurosurgery)
[2018, 32(2):196-200]

Cited: 1 time

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IL12Rβ1 defect presenting with massive intra-abdominal lymphadenopathy due to Mycobacterium intracellulare infection.

Eda Kepenekli Kadayifci, Ayşe Karaaslan, Serkan Atici, Gülşen Akkoç, Safa Bariş, Nurhayat Yakut, Sevliya Öcal Demir, Orhan Kaya KÖksalan, Ahmet Soysal, Caroline Deswarte, Jacinta Bustamante, Jean-Laurent Casanova, Mustafa Bakir,

Infections due to non-tuberculous mycobacteria species are problematic for immunodeficient individuals. Mendelian susceptibility to mycobacterial diseases (MSMD) defines a group of genetic defects affecting cellular interactions and the interferon (IFN)-γ pathway. Patients with MSMD may present with a disseminated infection resulting from the Bacillus Calmette-Guerin vaccine, Mycobacterium tuberculosis complex, environmental ... Read more >>

Asian Pac. J. Allergy Immunol. (Asian Pacific journal of allergy and immunology)
[2017, 35(3):161-165]

Cited: 1 time

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A rare and emerging pathogen: Raoultella planticola identification based on 16S rRNA in an infant.

Serkan Atıcı, Zeynep Alp Ünkar, Sevliya Öcal Demir, Gülşen Akkoç, Nurhayat Yakut, Şerife Yılmaz, Kübra Erdem, Aslı Çınar Memişoğlu, Nurver Ülger, Ahmet Soysal, Eren Özek, Mustafa Bakır,

Raoultella planticola is rarely associated with clinical infection, and a limited number of pediatric cases have been reported. Herein we report a case of bacteremia presumptively secondary to bilateral conjunctivitis in an infant caused by R. planticola which was successfully treated with piperacillin-tazobactam. It should be kept in mind that ... Read more >>

J Infect Public Health (Journal of infection and public health)
[2018, 11(1):130-132]

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Catheter-related Saccharomyces cerevisiae Fungemia Following Saccharomyces boulardii Probiotic Treatment: In a child in intensive care unit and review of the literature.

Serkan Atıcı, Ahmet Soysal, Kıvılcım Karadeniz Cerit, Şerife Yılmaz, Burak Aksu, Gürsu Kıyan, Mustafa Bakır,

Although Saccharomyces boulardii is usually a non-pathogenic fungus, in rare occasions it can cause invasive infection in children. We present the case of an 8-year-old patient in pediatric surgical intensive care unit who developed S. cerevisiae fungemia following probiotic treatment containing S. boulardii. Caspofungin was not effective in this case ... Read more >>

Med Mycol Case Rep (Medical mycology case reports)
[2017, 15:33-35]

Cited: 7 times

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Evaluation of the line probe assay for the rapid detection of bacterial meningitis pathogens in cerebrospinal fluid samples from children.

Ahmet Soysal, Demet Gedikbasi Toprak, Salih Türkoğlu, Mustafa Bakir,

The aim of this study is to compare the diagnostic performance of the line probe assay (LPA) with conventional multiplex polymerase chain reaction (PCR) for Streptococcus pneumoniae as well as real-time PCR for Neisseria meningitidis and Haemophilus influenzae type b (Hib) in cerebrospinal fluid (CSF) samples from children during the ... Read more >>

BMC Microbiol. (BMC microbiology)
[2017, 17(1):14]

Cited: 1 time

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Myiasis of the Toe as a Complication of a Neglected Wound: A Case Report.

Sevliya Öcal Demir, Ahmet Soysal, Gülşen Akkoç, Eda Kepenekli Kadayifci, Nurhayat Yakut, Nilgün Çerikçioğlu, Mustafa Bakir,

Wounds (Wounds : a compendium of clinical research and practice)
[2016, 28(11):E44-E46]

Cited: 0 times

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The diagnostic value of soluble urokinase plasminogen activator receptor (suPAR) compared to C-reactive protein (CRP) and procalcitonin (PCT) in children with systemic inflammatory response syndrome (SIRS).

Melis Şirinoğlu, Ahmet Soysal, Ayşe Karaaslan, Eda Kepenekli Kadayifci, Nilüfer Yalındağ-Öztürk, İsmail Cinel, Ali Yaman, Goncagül Haklar, Önder Şirikci, Serap Turan, Gülşen Altınkanat Gelmez, Güner Söyletir, Mustafa Bakır,

The aim of the present study was to determine the diagnostic and prognostic values of suPAR and to compare them to CRP and PCT in pediatric patients with systemic inflammatory response syndrome (SIRS).A prospective case-control study was performed.The study was performed in a tertiary university hospital which has a 649-bed ... Read more >>

J. Infect. Chemother. (Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy)
[2017, 23(1):17-22]

Cited: 5 times

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Intravenous Colistin Use for Multidrug-Resistant Gram-Negative Infections in Pediatric Patients.

Ayşe Karaaslan, Eren Çağan, Eda Kepenekli Kadayifci, Serkan Atıcı, Gülşen Akkoç, Nurhayat Yakut, Sevliya Öcal Demir, Ahmet Soysal, Mustafa Bakır,

The emergence of infections due to multidrug-resistant Gram-negative bacilli (MDR-GNB) has led to the resurrection of colistin use. The data on colistin use and drug-related adverse effects in children are scarce.In this study, we aimed to evaluate the clinical efficacy and safety of colistin use in critically ill pediatric patients.This ... Read more >>

Balkan Med J (Balkan medical journal)
[2016, 33(6):627-632]

Cited: 2 times

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Ventilator-associated pneumonia caused by Chryseobacterium indologenes: a rare infant case and review of the literature.

Serkan Atıcı, Zeynep Alp Ünkar, Kübra Erdem, Eda Kepenekli Kadayifci, Ayşe Karaaslan, Aslı Çınar Memişoğlu, Ahmet Soysal, Nurver Ülger Toprak, Güner Söyletir, Eren Özek, Mustafa Bakır,

Chryseobacterium indologenes is an uncommon organism that has been documented to cause a variety of invasive infections mostly in hospitalized patients with severe underlying diseases.A three-month-old female infant born at term by caesarean section with meningomyelocele and congenital diaphragmatic hernia had two surgeries for the repair of meningomyelocele and diaphragmatic ... Read more >>

Springerplus (SpringerPlus)
[2016, 5(1):1741]

Cited: 1 time

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First HIV-2 infection in a child in Turkey.

Eda Kepenekli Kadayifci, Ayşe Karaaslan, Kenan Midilli, Ahmet Soysal, Mustafa Bakır,

J Infect Dev Ctries (Journal of infection in developing countries)
[2016, 10(9):1042-1044]

Cited: 0 times

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Postoperative keratitis due to Paecilomyces: a rare pediatric case.

Ebru Toker, Nihan Ziyade, Serkan Atici, Kepenekli Kadayifçi Eda, Özden Türel, Demet Toprak, Merih Oray, Nilgün Cerikcioglu, Ahmet Soysal, Mustafa Bakir,

Fungal infections like Paecilomyces keratitis have emerged in childhood recently. The diagnosis and treatment of Paecilomyces keratitis is difficult and the outcome is usually poor. Corneal culture should be performed on fungal media such as Sabouraud glucose neopeptone agar (SDA) as soon as possible for diagnosis. We report a rare ... Read more >>

Pan Afr Med J (The Pan African medical journal)
[2016, 24:317]

Cited: 0 times

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Hospital acquired Clostridium difficile infection in pediatric wards: a retrospective case-control study.

Ayse Karaaslan, Ahmet Soysal, Nurhayat Yakut, Gulsen Akkoç, Sevliya Ocal Demir, Serkan Atıcı, Nurver Ulger Toprak, Guner Söyletir, Mustafa Bakır,

Clostridium difficile is a major cause of antibiotic-associated diarrhea and frequently results in healthcare-associated infections. The aim of this study was to determine the incidence and potential risk factors for C. difficile infection (CDI) in hospitalized children who developed diarrhea. A retrospective study was performed at a university hospital in ... Read more >>

Springerplus (SpringerPlus)
[2016, 5(1):1329]

Cited: 2 times

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Cutaneous Tuberculosis Occurring After a Skin Cut in a Child.

Gulsen Akkoc, Eda Kepenekli Kadayifci, Ayse Karaaslan, Serkan Atici, Nurhayat Yakut, Sevilya Ocal Demir, Gamze Akbas, Leyla Zeliha Cinel, Ahmet Soysal, Mustafa Bakir,

Tuberculosis is a common problem in Turkey, and cutaneous tuberculosis is a rare form of extrapulmonary tuberculosis. Herein, the authors describe a case of cutaneous tuberculosis (lupus vulgaris) occurring after contact with a sheep.A 15-year-old boy was admitted to Marmara University School of Medicine Pendik Training and Research Hospital (Istanbul, ... Read more >>

Wounds (Wounds : a compendium of clinical research and practice)
[2016, 28(8):E31-4]

Cited: 1 time

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The impact of a pneumococcal conjugate vaccination program on the nasopharyngeal carriage, serotype distribution and antimicrobial resistance of Streptococcus pneumoniae among healthy children in Turkey.

Ahmet Soysal, Esra Karabağ-Yılmaz, Eda Kepenekli, Ayşe Karaaslan, Eren Cagan, Serkan Atıcı, Gülşen Atınkanat-Gelmez, Peran Boran, Selim Merdan, Ufuk Hasdemir, Güner Söyletir, Mustafa Bakır,

The 7-valent conjugate pneumococcal vaccine (PCV7) was introduced by the Turkey National Immunization Program in 2008 and replaced by the PCV13 in 2011. We assessed the impact of PCV vaccination on the nasopharyngeal (NP) carriage, serotype distribution and antimicrobial resistance of Streptococcus pneumoniae (SP) among healthy Turkish children.A prospective surveillance ... Read more >>

Vaccine (Vaccine)
[2016, 34(33):3894-3900]

Cited: 9 times

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Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis.

Gulsen Akkoc, Eda Kepenekli Kadayifci, Ayse Karaaslan, Serkan Atici, Nurhayat Yakut, Sevliya Ocal Demir, Ahmet Soysal, Mustafa Bakir,

Epstein-Barr virus (EBV) usually causes mild, asymptomatic, and self-limited infections in children and adults; however, it may occasionally lead to severe conditions such as neurological diseases, malignant diseases, hepatic failure, and myocarditis. Epstein-Barr virus-related neurological disorders include meningitis, encephalitis, and cranial or peripheral neuritis, which are mostly seen in immunocompromised ... Read more >>

Case Rep Infect Dis (Case reports in infectious diseases)
[2016, 2016:7549252]

Cited: 1 time

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Neurologic Adverse Events Associated with Voriconazole Therapy: Report of Two Pediatric Cases.

Sevliya Öcal Demir, Serkan Atici, Gülşen Akkoç, Nurhayat Yakut, Nilay Baş İkizoğlu, Ela Erdem Eralp, Ahmet Soysal, Mustafa Bakir,

Although voriconazole, a triazole antifungal, is a safe drug, treatment with this agent is associated with certain adverse events such as hepatic, neurologic, and visual disturbances. The current report presents two cases, one a 9-year-old boy and the other a 17-year-old girl, who experienced neurologic side effects associated with voriconazole ... Read more >>

Case Rep Infect Dis (Case reports in infectious diseases)
[2016, 2016:3989070]

Cited: 0 times

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Prevalence of Metabolic Syndrome and Affecting Factors among Individuals Aged 30 and over in Balçova District of İzmir.

Ahmet Soysal, Hatice Şimşek, Sinem Doğanay, Türkan Günay,

The studies have shown that metabolic syndrome (MetS) leads to an increase twice as much in cardiovascular diseases (CVD) and four times as much in diabetes mellitus (DM) prevalence since the second half of the 20(th) century.This study aims to determine and discuss the prevalence of the MetS and co- ... Read more >>

Balkan Med J (Balkan medical journal)
[2016, 33(3):331-338]

Cited: 0 times

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