Full Text Journal Articles by
Author Ahmed Zaghloul

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A unique C-linked chalcone-dihydrochalcone dimer from Dracaena cinnabari resin.

Iman E Helal, Marwa Elsbaey, Ahmed M Zaghloul, El-Sayed S Mansour,

A new C-linked chalcone-dihydrochalcone dimer, named dracidione, was isolated from the ethyl acetate extract of dragon's blood resin of Dracaena cinnabari Balf. f. Structure elucidation of the new compound was carried out by means of one- and two-dimensional NMR spectroscopy in addition to high resolution mass spectrometry. The unique structure ... Read more >>

Nat. Prod. Res. (Natural product research)
[2019, :1-6]

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Non-invasive treatment of patients with upper extremity spasticity following stroke using paired trans-spinal and peripheral direct current stimulation.

Alexandra Paget-Blanc, Johanna L Chang, Maira Saul, Regina Lin, Zaghloul Ahmed, Bruce T Volpe,

Background:Muscle spasticity is a common impediment to motor recovery in patients with chronic stroke. Standard-of-care treatments such as botulinum toxin injections can temporarily relieve muscle stiffness and pain associated with spasticity, but often at the expense of increased muscle weakness. Recent preclinical investigations of a non-invasive treatment that pairs trans-spinal ... Read more >>

Bioelectron Med (Bioelectronic medicine)
[2019, 5:11]

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Methylenetetrahydrofolate Reductase Polymorphism and Premature Coronary Artery Disease.

Ahmed Zaghloul, Corina Iorgoveanu, Aakash Desai, Kathir Balakumaran, Kai Chen,

Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine re-methylation to methionine. Its deficiency leads to an increased serum level of homocysteine, which is well-known to be associated with premature coronary artery disease (CAD). Our case demonstrates the association of MTHFR polymorphism with premature CAD ... Read more >>

Cureus (Cureus)
[2019, 11(6):e5014]

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Effect of Girth Supersizing on Patient Satisfaction After Semi-Rigid Penile Implant Insertion: A Prospective Case-Control Study.

Ahmed Mahmoud Salem, Ihab Abdel Latef Osman, Ahmed Said Zaghloul, Mohamed Shokr Mohamed, Mohamed Nasreldin Sadek, Sameh Fayek GamalEl Din,

BACKGROUND:Penile length and girth have long been sources of anxiety for men. OBJECTIVES:The authors sought to measure satisfaction with intercourse and erectile function 3 and 6 months after girth augmentation in patients with semi-rigid penile implants who received autologous fat injections. METHODS:Thirty married participants in Egypt were recruited and divided ... Read more >>

Aesthet Surg J (Aesthetic surgery journal)
[2019, 39(7):NP259-NP265]

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Novel Speed-Controlled Automated Ladder Walking Device Reveals Walking Speed as a Critical Determinant of Skilled Locomotion after a Spinal Cord Injury in Adult Rats.

Tiffany M Richards, Pawan Sharma, Aaron Kuang, Douglas Whitty, Zaghloul Ahmed, Prithvi K Shah,

The horizontal ladder task is an established method to assess skilled locomotor recovery after neurological dysfunction. Walking speed is often used as a standardized measure in locomotor assessment of overground walking in human and pre-clinical studies, but the assessment of walking speed is typically ignored during skilled locomotor tasks. Ample ... Read more >>

J. Neurotrauma (Journal of neurotrauma)
[2019, 36(18):2698-2721]

Cited: 1 time

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Atypical Arrhythmia Associated with Lithium Therapy: When to Expect the Unexpected?

Corina Iorgoveanu, Ahmed Zaghloul, Teodora Donisan, Dinu Valentin Balanescu, Kathir Balakumaran, Serban Mihai Balanescu,

Acta Cardiol Sin (Acta Cardiologica Sinica)
[2019, 35(2):179-182]

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Repeated anodal trans-spinal direct current stimulation results in long-term reduction of spasticity in mice with spinal cord injury.

Wagdy Mekhael, Sultana Begum, Sreyashi Samaddar, Mazen Hassan, Pedro Toruno, Malik Ahmed, Alexis Gorin, Michael Maisano, Mark Ayad, Zaghloul Ahmed,

KEY POINTS:Spasticity is a disorder of muscle tone that is associated with lesions of the motor system. This condition involves an overactive spinal reflex loop that resists the passive lengthening of muscles. Previously, we established that application of anodal trans-spinal direct current stimulation (a-tsDCS) for short periods of time to ... Read more >>

J. Physiol. (Lond.) (The Journal of physiology)
[2019, 597(8):2201-2223]

Cited: 1 time

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Hypoglycemic, hypolipidemic and antioxidant effects of green sprouts juice and functional dairy micronutrients against streptozotocin-induced oxidative stress and diabetes in rats.

Rasha S Mohamed, Diaa A Marrez, Salah H Salem, Ahmed H Zaghloul, Ihab S Ashoush, Abdel Razik H Farrag, Ahmed M Abdel-Salam,

Hyperglycemia, the mark normal for diabetes and associated disorders are the main goals of natural diabetes therapies. In this context, the present research was designed to study the effects of fenugreek sprouts juice (FS), barley sprouts juice (BS), cell-free probiotic extract (cell-free PE), whey protein hydrolysate (WPH) and their mixture ... Read more >>

Heliyon (Heliyon)
[2019, 5(2):e01197]

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Hyaluronic acid injection in glans penis for treatment of premature ejaculation: a randomized controlled cross-over study.

Amr Alahwany, Mohamed W Ragab, Ahmed Zaghloul, Hamed Abdallah, Taymour Mostafa,

This randomized controlled cross-over study aimed to assess the efficacy and safety of glans penis injection with hyaluronic acid (HA) in treating premature ejaculation (PE). A total of 30 patients with PE were randomly allocated into two groups: group 1 (n = 15) which was subjected to glans penis HA injection and ... Read more >>

Int. J. Impot. Res. (International journal of impotence research)
[2019, 31(5):348-355]

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Active sero-survey for European bat lyssavirus type-1 circulation in North African insectivorous bats.

Jordi Serra-Cobo, Marc López-Roig, Rachel Lavenir, Elbia Abdelatif, Wahida Boucekkine, Mehdi Elharrak, Bachir Harif, Sehhar El Ayachi, Akram Ahmed Salama, Mohamed A Nayel, Ahmed Elsify, Sameh G El Rashedy, Paola De Benedictis, Franco Mutinelli, Barbara Zecchin, Dino Scaravelli, Chokri Balhoul, Ahmed Zaghawa, Hany Youssef Hassan, Ahmed Hamed Zaghloul, Hervé Bourhy,

Emerg Microbes Infect (Emerging microbes & infections)
[2018, 7(1):213]

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Calvarial osteomyelitis and intracranial extension post-Mohs micrographic surgery.

Aakash Desai, Anand Krishnan, Ahmed Zaghloul, Mitchell McClure,

Mohs micrographic surgery (MMS) is a specialised micrographic technique used for the treatment of locally invasive skin cancers. Despite being a relatively low risk surgery, the overall complication rates range between 1.6% and 3%. Common complications include postoperative haemorrhage, haematoma formation, wound infection, wound dehiscence and flap/graft necrosis. Osteomyelitis after ... Read more >>

BMJ Case Rep (BMJ case reports)
[2018, 2018:]

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Limitations of Coronary Computed Tomography Angiography in Predicting Acute Coronary Syndrome in a Low to Intermediate-risk Patient with Chest Pain.

Ahmed Zaghloul, Corina Iorgoveanu, Kathir Balakumaran, Dinu V Balanescu, Teodora Donisan,

The optimal management of patients with chest pain relies on the prognostic information provided by noninvasive cardiovascular testing. Coronary computed tomography angiography (CCTA) is an increasingly utilized, highly accurate noninvasive test for diagnosing coronary artery disease. We illustrate an exceptional limitation of the prognostic information provided by CCTA. A 46-year-old ... Read more >>

Cureus (Cureus)
[2018, 10(5):e2649]

Cited: 1 time

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Prosthetic Tricuspid Valve Thrombosis.

Ahmed Zaghloul, Corina Iorgoveanu, Aakash Desai, Molly Silkowski, Kathir Balakumaran,

Prosthetic valve thrombosis, a serious complication of prosthetic valve replacement, can be lethal without proper treatment. Right-sided valve thrombosis is rare but several therapeutic modalities can be considered: anticoagulation therapy, fibrinolysis, or surgery. Here, we report a case of significant tricuspid valve thrombosis which failed fibrinolytic therapy requiring repeat sternotomy with repeat ... Read more >>

Cureus (Cureus)
[2018, 10(7):e2928]

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Hypertensive Crisis in Cardiac Tamponade.

Corina Iorgoveanu, Ahmed Zaghloul, Aakash Desai, Kathir Balakumaran, Kai Chen,

Cardiac tamponade is a potentially life-threatening disorder believed to be commonly associated with hypotension and even shock. However, many patients with subacute tamponade are indeed hypertensive at initial presentation. We present a case of a 76-year-old female with hypertensive crisis in the settings of cardiac tamponade whose blood pressure normalized after ... Read more >>

Cureus (Cureus)
[2018, 10(6):e2873]

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A Case of Brugada Pattern Associated with Adrenal Insufficiency.

Corina Iorgoveanu, Ahmed Zaghloul, Aakash Desai, Kathir Balakumaran, Muhammad Y Adeel,

Brugada syndrome (BrS) is an inherited channelopathy disease, caused by genetic changes in transmembrane ion channels. It has an increased risk of sudden cardiac death (SCD) in the absence of a structural heart disease. We report a case in which the presenting electrocardiogram (EKG) exhibited a type 1 Brugada-like pattern ... Read more >>

Cureus (Cureus)
[2018, 10(6):e2752]

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Bilateral Earlobe Crease as a Marker of Premature Coronary Artery Disease.

Corina Iorgoveanu, Ahmed Zaghloul, Aakash Desai, Anand M Krishnan, Kathir Balakumaran,

Cardiovascular diseases, including heart disease and stroke, are the world's largest killers. More than 800,000 people die from cardiovascular disease each year in the United States (US). Heart disease is estimated to cost 200 billion US Dollars (USD) annually. Early identification of an inexpensive marker which allows for early intervention ... Read more >>

Cureus (Cureus)
[2018, 10(5):e2616]

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Unresponsive Intractable Chronic Headache With Sitagliptin.

Ahmed Zaghloul, Corina Iorgoveanu, Andrew Polio, Aakash Desai,

Sitagliptin is an anti-diabetic medication within the dipeptidyl peptidase 4 (DPP4) inhibitor class used as a single agent or in combination therapy. It is a well-studied and well-tolerated medication with commonly reported adverse events of upper respiratory tract infections, nasopharyngitis, headache, and gastrointestinal (GI) upset. Post-marketing reports have also identified associations ... Read more >>

Cureus (Cureus)
[2018, 10(4):e2537]

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Kikuchi-Fujimoto Disease in a Young African American Male.

Ahmed Zaghloul, Corina Iorgoveanu, Andrew Polio, Aakash Desai,

Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is an extremely rare, self-limiting disorder which typically presents with fever and painful, unilateral cervical lymphadenopathy in previously healthy individuals. Here, we describe a case of KFD which initially presented with fever of unknown origin. Due to its non-specific symptoms and ... Read more >>

Cureus (Cureus)
[2018, 10(4):e2508]

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Lyme Meningoencephalitis Masquerading as Normal Pressure Hydrocephalus.

Aakash Desai, Gaurav Manek, Anand M Krishnan, Corina Iorgoveanu, Ahmed Zaghloul,

Lyme disease is a tick-borne illness caused primarily by the spirochete Borrelia burgdorferi. The disease is most prevalent in forested areas endemic for Ixodes tick, which transmits the spirochete. Here, we describe a case of Lyme meningoencephalitis masquerading as normal pressure hydrocephalus (NPH) which initially presented with urinary incontinence, gait ... Read more >>

Cureus (Cureus)
[2018, 10(4):e2417]

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Case Report: A rare case of prosthetic valve infective endocarditis caused by Aerococcus urinae

Muhammad Adeel, Saman Tariq, Hisham Akthar, Ahmed Zaghloul, Corina Iorgoveanu, Carina Dehner,

Infective endocarditis (IE) is a serious and life-threatening cardiac condition, most commonly caused by staphylococci, Streptococcus viridans, and enterococci. However, in special settings, IE can be caused by rare organisms. Here we present a case of IE caused by Aerococcus urinae in a 75-year-old man with a bioprosthetic aortic valve.  ... Read more >>

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A proinflammatory response of bovine endometrial epithelial cells to active sperm in vitro.

Ahmed E Elweza, Mohamed A Ezz, Tomas J Acosta, Anup K Talukder, Takashi Shimizu, Hiroyuki Hayakawa, Masayuki Shimada, Kazuhiko Imakawa, Ahmed H Zaghloul, Akio Miyamoto,

In the cow, cryopreserved semen is inseminated into the uterus, and most of sperm are removed by backflow and phagocytes. Nevertheless, the mechanism responsible for sperm phagocytosis is unclear. Here, we used cultured bovine uterine epithelial cells (BUECs) to investigate the uterine response to sperm and the mechanism that activates ... Read more >>

Mol. Reprod. Dev. (Molecular reproduction and development)
[2018, 85(3):215-226]

Cited: 1 time

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Case Report: A rare case of prosthetic valve infective endocarditis caused by Aerococcus urinae.

Muhammad Adeel, Saman Tariq, Hisham Akthar, Ahmed Zaghloul, Corina Iorgoveanu, Carina Dehner,

Infective endocarditis (IE) is a serious and life-threatening cardiac condition, most commonly caused by staphylococci, Streptococcus viridans, and enterococci. However, in special settings, IE can be caused by rare organisms. Here we present a case of IE caused by Aerococcus urinae in a 75-year-old man with a bioprosthetic aortic valve.  ... Read more >>

F1000Res (F1000Research)
[2017, 6:1998]

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Randomized, double-blind, placebo-controlled, interventional phase IV investigation to assess the efficacy and safety of r-hirudin gel (1120I.U) in patients with hematomas.

Hani El-Mowafi, Ahmed El Araby, Yasser Kandil, Ahmed Zaghloul,

Background:Hirudin is the most potent direct thrombin inhibitor, and recombinant forms are routinely used in anticoagulation therapy. Recombinant hirudin gels are commercially available for the treatment of hematomas and associated symptoms. Objectives:To assess the efficacy and safety of a topically administered recombinant hirudin gel in patients with hematomas. Patients/Methods:This double-blind, ... Read more >>

Res Pract Thromb Haemost (Research and practice in thrombosis and haemostasis)
[2018, 2(1):139-146]

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Effects of cathodal trans-spinal direct current stimulation on lower urinary tract function in normal and spinal cord injury mice with overactive bladder.

Zaghloul Ahmed,

OBJECTIVE:Lower urinary tract (LUT) dysfunction is a monumental problem affecting quality of life following neurotrauma, such as spinal cord injury (SCI). Proper function of the bladder and its associated structures depends on coordinated activity of the neuronal circuitry in the spinal cord and brain. Disconnection between the spinal and brain ... Read more >>

J Neural Eng (Journal of neural engineering)
[2017, 14(5):056002]

Cited: 2 times

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Cytotoxic constituents of Alocasia macrorrhiza.

Marwa Elsbaey, Kadria F M Ahmed, Mahmoud F Elsebai, Ahmed Zaghloul, Mohamed M A Amer, Mohamed-Farid I Lahloub,

An indole alkaloid, 2-(5-hydroxy-1H-indol-3-yl)-2-oxo-acetic acid (1) isolated for the first time from nature, in addition to the nine known compounds 5-hydroxy-1H-indole-3-carboxylic acid methyl ester (2), alocasin B (3), hyrtiosin B (4), α-monopalmitin (5), 1-O-β-D-glucopyranosyl-(2S, 3R, 4E, 8Z)-2-[(2(R)-hydroctadecanoyl) amido]-4,8-octadecadiene-1,3-diol (6), 3-epi-betulinic acid (7), 3-epi-ursolic acid (8), β-sitosterol (9) and β-sitosterol 3-O-β-D-glucoside ... Read more >>

Z. Naturforsch., C, J. Biosci. (Zeitschrift fur Naturforschung. C, Journal of biosciences)
[2017, 72(1-2):21-25]

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