Full Text Journal Articles by
Author Ahmad Majzoub

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Predictive model to estimate the chances of successful sperm retrieval by testicular sperm aspiration in patients with nonobstructive azoospermia.

Ahmad Majzoub, Mohamed Arafa, Kareim Khalafalla, Sami AlSaid, Hasan Burjaq, Moza Albader, Thoraya Al-Marzooqi, Sandro C Esteves, Haitham Elbardisi,

OBJECTIVE:To explore predictors of successful sperm retrieval (SR) and to identify potentially suitable candidates for testicular sperm aspiration (TESA), a more straightforward, less traumatic, and less costly procedure than open surgical SR methods. DESIGN:Retrospective chart review. SETTING:Academic tertiary medical center. PATIENTS:A total of 297 patients with nonobstructive azoospermia. INTERVENTIONS:All patients ... Read more >>

Fertil Steril (Fertility and sterility)
[2020, :]

Cited: 0 times

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Sperm DNA Fragmentation: A New Guideline for Clinicians.

Ashok Agarwal, Ahmad Majzoub, Saradha Baskaran, Manesh Kumar Panner Selvam, Chak Lam Cho, Ralf Henkel, Renata Finelli, Kristian Leisegang, Pallav Sengupta, Catalina Barbarosie, Neel Parekh, Marco G Alves, Edmund Ko, Mohamed Arafa, Nicholas Tadros, Ranjith Ramasamy, Parviz Kavoussi, Rafael Ambar, Manish Kuchakulla, Kathy Amy Robert, Concetta Iovine, Damayanthi Durairajanayagam, Sunil Jindal, Rupin Shah,

Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic content. Testicular (defective maturation and abortive apoptosis) and post-testicular (oxidative stress) mechanisms are implicated in the etiology ... Read more >>

World J Mens Health (The world journal of men's health)
[2020, 38(4):412-471]

Cited: 0 times

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Best laboratory practices and therapeutic interventions to reduce sperm DNA damage.

Marlon Martinez, Ahmad Majzoub,

Conventional semen analysis is considered the cornerstone investigation for infertile men. Nonetheless, this routine test does not provide information on important sperm functions like sperm DNA fragmentation (SDF). Abnormalities of human spermatozoal nucleus and chromatin have a detrimental impact on both natural and assisted reproductive outcomes. In vivo, SDF results ... Read more >>

Andrologia (Andrologia)
[2020, :e13736]

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The Use of Testicular Sperm for Intracytoplasmic Sperm Injection in Patients with High Sperm DNA Damage: A Systematic Review.

Rafael F Ambar, Ashok Agarwal, Ahmad Majzoub, Sarah Vij, Nicholas N Tadros, Chak Lam Cho, Neel Parekh, Edson Borges, Sidney Glina,

The advent of intracytoplasmic sperm injection (ICSI) has changed the human reproduction landscape by overcoming several limitations related to both male and female infertility factors. However, despite the development of new technologies, the live-birth rate with ICSI has not exceeded 30%. In order to improve assisted reproductive technology outcomes, advanced ... Read more >>

World J Mens Health (The world journal of men's health)
[2020, :]

Cited: 0 times

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Predictors of surgical sperm retrieval in non-obstructive azoospermia: summary of current literature.

Muhammad A Arshad, Ahmad Majzoub, Sandro C Esteves,

Intracytoplasmic sperm injection (ICSI), combined with surgical sperm retrieval (SR) techniques, is the sole option for patients with non-obstructive azoospermia to achieve fertility; however, with suboptimal results. Given the variability in clinical presentation, the potential role of factors that can predict the likelihood of successful testicular SR needs to be ... Read more >>

Int Urol Nephrol (International urology and nephrology)
[2020, 52(11):2015-2038]

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Seminal oxidation-reduction potential levels are not influenced by the presence of leucocytospermia.

Mohamed Arafa, Ralf Henkel, Ashok Agarwal, Kathy Robert, Renata Finelli, Ahmad Majzoub, Haitham ElBardisi,

Oxidative stress (OS) is characterised by an excessive amount of reactive oxygen species (ROS) which negatively affect sperm functions. In this study, the influence of leucocytes on seminal oxidation-reduction potential (ORP) and sperm DNA fragmentation (SDF) was investigated in 1,068 men. Seminal leucocyte concentration did not correlate with SDF, unadjusted ... Read more >>

Andrologia (Andrologia)
[2020, 52(7):e13609]

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SARS-CoV-2 pandemic and repercussions for male infertility patients: A proposal for the individualized provision of andrological services.

Sandro C Esteves, Francesco Lombardo, Nicolás Garrido, Juan Alvarez, Armand Zini, Giovanni M Colpi, Jackson Kirkman-Brown, Sheena E M Lewis, Lars Björndahl, Ahmad Majzoub, Chak-Lam Cho, Pedro Vendeira, Jorge Hallak, Edouard Amar, Marcello Cocuzza, Fabiola C Bento, Rita C Figueira, Romualdo Sciorio, Rita J Laursen, Ahmad M Metwalley, Sunil K Jindal, Sijo Parekattil, Ranjith Ramasamy, Carlo Alviggi, Peter Humaidan, John L Yovich, Ashok Agarwal,

The prolonged lockdown of health facilities providing non-urgent gamete cryopreservation-as currently recommended by many reproductive medicine entities and regulatory authorities due to the SARS-CoV-2 pandemic will be detrimental for subgroups of male infertility patients. We believe the existing recommendations should be promptly modified and propose that the same permissive approach ... Read more >>

Andrology (Andrology)
[2020, :]

Cited: 4 times

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Correlation of oxidation reduction potential and total motile sperm count: its utility in the evaluation of male fertility potential.

Ahmad Majzoub, Mohamed Arafa, Walid El Ansari, Mohammed Mahdi, Ashok Agarwal, Sami Al-Said, Haitham Elbardisi,

Oxidative stress (OS) is detrimental to sperm functions, and the oxidation reduction potential (ORP) is a good measure of OS as it considers the balance between oxidants and reductants. Total motile sperm count (TMSC) is viewed as the single most important semen analysis parameter that can predict male infertility severity, ... Read more >>

Asian J. Androl. (Asian journal of andrology)
[2020, 22(3):317-322]

Cited: 2 times

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Serum testosterone status in men with penile corporoveno-occlusive dysfunction.

Onder Canguven, Ahmad H Al-Malki, Ahmad Majzoub,

Background and objectives: Vascular abnormalities are the most common factors in patients with erectile dysfunction (ED). There are limited number of case series investigating the etiology of corporoveno-occlusive dysfunction (CVOD). In this study, we evaluated ED patients with vascular etiologies and their serum biomarkers from a large database.Materials and methods: ... Read more >>

Aging Male (The aging male : the official journal of the International Society for the Study of the Aging Male)
[2020, :1-5]

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Efficacy of Antioxidant Supplementation on Conventional and Advanced Sperm Function Tests in Patients with Idiopathic Male Infertility.

Mohamed Arafa, Ashok Agarwal, Ahmad Majzoub, Manesh Kumar Panner Selvam, Saradha Baskaran, Ralf Henkel, Haitham Elbardisi,

Antioxidants are used in the empirical treatment of infertile men. The aim of this study was to evaluate the effects of antioxidant therapy on conventional semen parameters and advanced sperm function tests in men seeking fertility treatment. A total of 148 infertile men of unknown etiology were divided into idiopathic ... Read more >>

Antioxidants (Basel) (Antioxidants (Basel, Switzerland))
[2020, 9(3):]

Cited: 1 time

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Predictive value of oxidative stress testing in semen for sperm DNA fragmentation assessed by sperm chromatin dispersion test.

Haitham Elbardisi, Renata Finelli, Ashok Agarwal, Ahmad Majzoub, Ralf Henkel, Mohamed Arafa,

BACKGROUND:Although standard semen analysis is a cornerstone of male infertility investiation, it has significant limitations. Seminal oxidative stress and DNA damage have shown potential to better predict male fertility potential and provide improved diagnostic and management strategies. OBJECTIVE:The aim of this study was to investigate whether seminal oxidation-reduction potential (ORP), ... Read more >>

Andrology (Andrology)
[2020, 8(3):610-617]

Cited: 1 time

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Does varicocelectomy improve semen in men with azoospermia and clinically palpable varicocele?

Haitham Elbardisi, Walid El Ansari, Ahmad Majzoub, Mohamad Arafa,

The effectiveness of varicocelectomy in nonobstructive azoospermia is controversial. The current study assessed the efficacy of microsurgical subinguinal varicocelectomy in nonobstructive azoospermic men with palpable varicocele and to evaluate predictive parameters of outcome. We reviewed the records of 723 patients who had microsurgical varicocelectomy and diagnostic testicular biopsy between 2012 ... Read more >>

Andrologia (Andrologia)
[2020, 52(2):e13486]

Cited: 1 time

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Is there plagiarism in the most influential publications in the field of andrology?

Saradha Baskaran, Ashok Agarwal, Manesh Kumar Panner Selvam, Ralf Henkel, Damayanthi Durairajanayagam, Kristian Leisegang, Ahmad Majzoub, Dipty Singh, Kareim Khalafalla,

Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology articles. A total of 77 highly cited andrology articles were analysed for their similarity index using iThenticate ... Read more >>

Andrologia (Andrologia)
[2019, 51(10):e13405]

Cited: 0 times

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Premature ejaculation: an update on definition and pathophysiology.

Mohammed Abu El-Hamd, Ramadan Saleh, Ahmad Majzoub,

Premature ejaculation (PE) is the most common male sexual dysfunction, which represents a diagnostic as well as a therapeutic challenge for physicians. However, no universally accepted definition is currently available for PE. As a result, physicians continue to diagnose patients with PE according to major guidelines set by the professional ... Read more >>

Asian J Androl (Asian journal of andrology)
[2019, 21(5):425-432]

Cited: 1 time

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A Schematic Overview of the Current Status of Male Infertility Practice.

Ashok Agarwal, Ahmad Majzoub, Neel Parekh, Ralf Henkel,

The practice of male infertility has dramatically evolved over the past few decades. This has been achieved after the realization of the important contribution the male counterpart holds in the couple's infertility. It is also supported by a number of breakthroughs in the diagnosis and treatment of this medical condition. ... Read more >>

World J Mens Health (The world journal of men's health)
[2020, 38(3):308-322]

Cited: 1 time

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Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility.

Ashok Agarwal, Neel Parekh, Manesh Kumar Panner Selvam, Ralf Henkel, Rupin Shah, Sheryl T Homa, Ranjith Ramasamy, Edmund Ko, Kelton Tremellen, Sandro Esteves, Ahmad Majzoub, Juan G Alvarez, David K Gardner, Channa N Jayasena, Jonathan W Ramsay, Chak Lam Cho, Ramadan Saleh, Denny Sakkas, James M Hotaling, Scott D Lundy, Sarah Vij, Joel Marmar, Jaime Gosalvez, Edmund Sabanegh, Hyun Jun Park, Armand Zini, Parviz Kavoussi, Sava Micic, Ryan Smith, Gian Maria Busetto, Mustafa Emre Bakırcıoğlu, Gerhard Haidl, Giancarlo Balercia, Nicolás Garrido Puchalt, Moncef Ben-Khalifa, Nicholas Tadros, Jackson Kirkman-Browne, Sergey Moskovtsev, Xuefeng Huang, Edson Borges, Daniel Franken, Natan Bar-Chama, Yoshiharu Morimoto, Kazuhisa Tomita, Vasan Satya Srini, Willem Ombelet, Elisabetta Baldi, Monica Muratori, Yasushi Yumura, Sandro La Vignera, Raghavender Kosgi, Marlon P Martinez, Donald P Evenson, Daniel Suslik Zylbersztejn, Matheus Roque, Marcello Cocuzza, Marcelo Vieira, Assaf Ben-Meir, Raoul Orvieto, Eliahu Levitas, Amir Wiser, Mohamed Arafa, Vineet Malhotra, Sijo Joseph Parekattil, Haitham Elbardisi, Luiz Carvalho, Rima Dada, Christophe Sifer, Pankaj Talwar, Ahmet Gudeloglu, Ahmed M A Mahmoud, Khaled Terras, Chadi Yazbeck, Bojanic Nebojsa, Damayanthi Durairajanayagam, Ajina Mounir, Linda G Kahn, Saradha Baskaran, Rishma Dhillon Pai, Donatella Paoli, Kristian Leisegang, Mohamed Reza Moein, Sonia Malik, Onder Yaman, Onder Yaman, Luna Samanta, Fouad Bayane, Sunil K Jindal, Muammer Kendirci, Baris Altay, Dragoljub Perovic, Avi Harlev,

Despite advances in the field of male reproductive health, idiopathic male infertility, in which a man has altered semen characteristics without an identifiable cause and there is no female factor infertility, remains a challenging condition to diagnose and manage. Increasing evidence suggests that oxidative stress (OS) plays an independent role ... Read more >>

World J Mens Health (The world journal of men's health)
[2019, 37(3):296-312]

Cited: 10 times

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Clinical utility of sperm DNA damage in male infertility.

Ahmad Majzoub, Ashok Agarwal, Sandro C Esteves,

Sperm DNA fragmentation (SDF) is an advanced test of sperm function that is utilized during male fertility evaluation. Recently, a guideline was published highlighting the detrimental impact of SDF on sperm function identifying practice-based clinical indications for SDF testing. This review illustrates the commonly utilized SDF measurement techniques and explores ... Read more >>

Panminerva Med (Panminerva medica)
[2019, 61(2):118-127]

Cited: 1 time

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Oxidative stress and sperm function: A systematic review on evaluation and management.

Sulagna Dutta, Ahmad Majzoub, Ashok Agarwal,

Objective: To review and present the most distinct concepts on the association of reactive oxygen species (ROS) with male reproduction. Methods: The Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) guidelines were used to search PubMed, Medline, EMBASE, and the Cochrane electronic databases for studies investigating the role ... Read more >>

(Arab journal of urology)
[2019, 17(2):87-97]

Cited: 6 times

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Correlation of oxidation-reduction potential with hormones, semen parameters and testicular volume.

Mohamed Arafa, Ralf Henkel, Ashok Agarwal, Ahmad Majzoub, Haitham Elbardisi,

Seminal oxidative stress (OS) is a major cause of male factor infertility and can be measured as oxidation-reduction potential (ORP). Studies showed significant negative relationships of ORP with sperm count, motility or DNA integrity. Since these parameters are also positively or negatively associated with reproductive hormones follicle-stimulating hormone (FSH), luteinising ... Read more >>

Andrologia (Andrologia)
[2019, 51(5):e13258]

Cited: 1 time

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Metabolic Syndrome and Male Fertility.

Ana Dias Martins, Ahmad Majzoub, Ashok Agawal,

Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through studying the relationship between MetS ... Read more >>

World J Mens Health (The world journal of men's health)
[2019, 37(2):113-127]

Cited: 4 times

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Management and outcomes of hyperparathyroidism: a case series from a single institution over two decades.

Hassan Al-Thani, Moamena El-Matbouly, Maryam Al-Sulaiti, Mohammad Asim, Ahmad Majzoub, Abdelhakem Tabeb, Ayman El-Menyar,

Background:Hyperparathyroidism is a frequent endocrine disorder with variable clinical manifestations and outcomes. We aimed to evaluate clinical presentations, management and outcomes of hyperparathyroidism. Methods:A retrospective study was conducted to include all patients presented with hyperparathyroidism between 1995 and 2014 at a single tertiary hospital with an average follow-up period of ... Read more >>

Ther Clin Risk Manag (Therapeutics and clinical risk management)
[2018, 14:1337-1345]

Cited: 0 times

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Geographical differences in semen characteristics of 13 892 infertile men.

Haitham Elbardisi, Ahmad Majzoub, Sami Al Said, Khalid Al Rumaihi, Walid El Ansari, Alia Alattar, Mohamed Arafa,

Objective:To assess the relationship between geographical differences and all semen parameters, across 13,892 infertile men of 84 diverse nationalities, recruited at a specialised tertiary hospital that represents the main healthcare provider in Qatar. Male infertility is an important and global public health problem. Despite this, there is a significant scarcity ... Read more >>

Arab J Urol (Arab journal of urology)
[2018, 16(1):3-9]

Cited: 1 time

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Oxidation-reduction potential and sperm DNA fragmentation, and their associations with sperm morphological anomalies amongst fertile and infertile men.

Ahmad Majzoub, Mohamad Arafa, Mohamed Mahdi, Ashok Agarwal, Sami Al Said, Ibrahim Al-Emadi, Walid El Ansari, Alia Alattar, Khalid Al Rumaihi, Haitham Elbardisi,

Objective:To assess seminal oxidation-reduction potential (ORP) and sperm DNA fragmentation (SDF) in male infertility and their relationships with sperm morphology in fertile and infertile men. Patients and methods:Prospective case-control study comparing the findings of infertile men (n = 1168) to those of men with confirmed fertility (n = 100) regarding demographics and semen characteristics ... Read more >>

Arab J Urol (Arab journal of urology)
[2018, 16(1):87-95]

Cited: 9 times

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Arab J Urol.

Ashok Agarwal, Ahmad Majzoub, Mohamed Arafa, Haitham Elbardisi,

Arab J Urol (Arab journal of urology)
[2018, 16(1):1-2]

Cited: 0 times

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Systematic review of antioxidant types and doses in male infertility: Benefits on semen parameters, advanced sperm function, assisted reproduction and live-birth rate.

Ahmad Majzoub, Ashok Agarwal,

Objective:To explore the current evidence concerning the effect of oral antioxidant supplementation on various male fertility outcomes, as antioxidants are widely available compounds that are commonly used for the treatment of male infertility. Materials and methods:PubMed, Medline and Cochrane electronic databases were searched according to a modified Preferred Reporting Items ... Read more >>

(Arab journal of urology)
[2018, 16(1):113-124]

Cited: 15 times

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