Full Text Journal Articles by
Author Adrian Jonas

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Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource.

Angela Wood, Rachel Denholm, Sam Hollings, Jennifer Cooper, Samantha Ip, Venexia Walker, Spiros Denaxas, Ashley Akbari, Amitava Banerjee, William Whiteley, Alvina Lai, Jonathan Sterne, Cathie Sudlow, ,

<h4>Objective</h4>To describe a novel England-wide electronic health record (EHR) resource enabling whole population research on covid-19 and cardiovascular disease while ensuring data security and privacy and maintaining public trust.<h4>Design</h4>Data resource comprising linked person level records from national healthcare settings for the English population, accessible within NHS Digital's new trusted research ... Read more >>

BMJ (BMJ (Clinical research ed.))
[2021, 373:n826]

Cited: 4 times

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Laboratory quick near edge x-ray absorption fine structure spectroscopy in the soft x-ray range with 100 Hz frame rate using CMOS technology.

Adrian Jonas, Steffen Staeck, Birgit Kanngießer, Holger Stiel, Ioanna Mantouvalou,

In laboratory based x-ray absorption fine structure (XAFS) spectroscopy, the slow readout speed of conventional CCD cameras can prolong the measuring times by multiple orders of magnitude. Using pulsed sources, e.g., laser-based x-ray sources, the pulse repetition rate often exceeds the frame rate of the CCD camera. We report the ... Read more >>

Rev Sci Instrum (The Review of scientific instruments)
[2021, 92(2):023102]

Cited: 0 times

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Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension.

Samantha Cruz Rivera, Xiaoxuan Liu, An-Wen Chan, Alastair K Denniston, Melanie J Calvert, ,

The SPIRIT 2013 statement aims to improve the completeness of clinical trial protocol reporting by providing evidence-based recommendations for the minimum set of items to be addressed. This guidance has been instrumental in promoting transparent evaluation of new interventions. More recently, there has been a growing recognition that interventions involving ... Read more >>

Lancet Digit Health (The Lancet. Digital health)
[2020, 2(10):e549-e560]

Cited: 9 times

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Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI Extension.

Xiaoxuan Liu, Samantha Cruz Rivera, David Moher, Melanie J Calvert, Alastair K Denniston, ,

The CONSORT 2010 (Consolidated Standards of Reporting Trials) statement provides minimum guidelines for reporting randomised trials. Its widespread use has been instrumental in ensuring transparency when evaluating new interventions. More recently, there has been a growing recognition that interventions involving artificial intelligence (AI) need to undergo rigorous, prospective evaluation to ... Read more >>

BMJ (BMJ (Clinical research ed.))
[2020, 370:m3164]

Cited: 14 times

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Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension.

Xiaoxuan Liu, Samantha Cruz Rivera, David Moher, Melanie J Calvert, Alastair K Denniston, ,

The CONSORT 2010 statement provides minimum guidelines for reporting randomized trials. Its widespread use has been instrumental in ensuring transparency in the evaluation of new interventions. More recently, there has been a growing recognition that interventions involving artificial intelligence (AI) need to undergo rigorous, prospective evaluation to demonstrate impact on ... Read more >>

Nat Med (Nature medicine)
[2020, 26(9):1364-1374]

Cited: 41 times

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Transient Sub-nanosecond Soft X-ray NEXAFS Spectroscopy on Organic Thin Films.

Adrian Jonas, Katharina Dammer, Holger Stiel, Birgit Kanngiesser, Rocío Sánchez-de-Armas, Ioanna Mantouvalou,

We demonstrate visible pump soft X-ray probe near-edge X-ray absorption fine structure (NEXAFS) spectroscopy measurements at the carbon K edge on thin molecular films in the laboratory. This opens new opportunities through the use of laboratory equipment for chemical speciation. We investigate the metal-free porphyrin derivative tetra(<i>tert</i>-butyl)porphyrazine as an ideal ... Read more >>

Anal Chem (Analytical chemistry)
[2020, 92(23):15611-15615]

Cited: 0 times

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Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI Extension.

Samantha Cruz Rivera, Xiaoxuan Liu, An-Wen Chan, Alastair K Denniston, Melanie J Calvert, ,

The SPIRIT 2013 (The Standard Protocol Items: Recommendations for Interventional Trials) statement aims to improve the completeness of clinical trial protocol reporting, by providing evidence-based recommendations for the minimum set of items to be addressed. This guidance has been instrumental in promoting transparent evaluation of new interventions. More recently, there ... Read more >>

BMJ (BMJ (Clinical research ed.))
[2020, 370:m3210]

Cited: 16 times

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Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension.

Xiaoxuan Liu, Samantha Cruz Rivera, David Moher, Melanie J Calvert, Alastair K Denniston, ,

The CONSORT 2010 statement provides minimum guidelines for reporting randomised trials. Its widespread use has been instrumental in ensuring transparency in the evaluation of new interventions. More recently, there has been a growing recognition that interventions involving artificial intelligence (AI) need to undergo rigorous, prospective evaluation to demonstrate impact on ... Read more >>

Lancet Digit Health (The Lancet. Digital health)
[2020, 2(10):e537-e548]

Cited: 7 times

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Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension.

Samantha Cruz Rivera, Xiaoxuan Liu, An-Wen Chan, Alastair K Denniston, Melanie J Calvert, , , ,

The SPIRIT 2013 statement aims to improve the completeness of clinical trial protocol reporting by providing evidence-based recommendations for the minimum set of items to be addressed. This guidance has been instrumental in promoting transparent evaluation of new interventions. More recently, there has been a growing recognition that interventions involving ... Read more >>

Nat Med (Nature medicine)
[2020, 26(9):1351-1363]

Cited: 33 times

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Bringing NHS data analysis into the 21st century.

Ben Goldacre, Martin Bardsley, Tim Benson, Kate Cheema, Roger Chinn, Ellen Coughlan, Sarah Dougan, Marc Farr, Loraine Hawkins, Adrian Jonas, Andy Kinnear, Morag Mcinnes, Mohammed Amin Mohammed, Caroline Morton, Rahul Pasumarthy, Neil Pettinger, Ben Rowland, Neil Sebire, Paul Stroner, Jeni Tennison, Samantha Warnakula, Oliver Watson, Emma Wright, Hamish Young, Jessica Morley,

J R Soc Med (Journal of the Royal Society of Medicine)
[2020, 113(10):383-388]

Cited: 2 times

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Machine learning and artificial intelligence research for patient benefit: 20 critical questions on transparency, replicability, ethics, and effectiveness.

Sebastian Vollmer, Bilal A Mateen, Gergo Bohner, Franz J Király, Rayid Ghani, Pall Jonsson, Sarah Cumbers, Adrian Jonas, Katherine S L McAllister, Puja Myles, David Granger, Mark Birse, Richard Branson, Karel G M Moons, Gary S Collins, John P A Ioannidis, Chris Holmes, Harry Hemingway,

BMJ (BMJ (Clinical research ed.))
[2020, 368:l6927]

Cited: 29 times

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Toroidal multilayer mirrors for laboratory soft X-ray grazing emission X-ray fluorescence.

Jonas Baumann, Adrian Jonas, Ruth Reusch, Veronika Szwedowski-Rammert, Malte Spanier, Daniel Grötzsch, Kevin Bethke, Beatrix Pollakowski-Herrmann, Markus Krämer, Thomas Holz, Reiner Dietsch, Ioanna Mantouvalou, Birgit Kanngießer,

Efficient soft X-ray spectroscopy in the laboratory is still a challenging task. Here, we report on new toroidal multilayer optics designed and applied with the laser-produced plasma (LPP) source of the Berlin Laboratory for innovative X-ray technologies. The optics are described and characterized, and the application of the updated source ... Read more >>

Rev Sci Instrum (The Review of scientific instruments)
[2020, 91(1):016102]

Cited: 0 times

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Towards Poisson noise limited optical pump soft X-ray probe NEXAFS spectroscopy using a laser-produced plasma source.

Adrian Jonas, Holger Stiel, Lisa Glöggler, Diana Dahm, Katharina Dammer, Birgit Kanngießer, Ioanna Mantouvalou,

We present a laboratory setup for near edge X-ray absorption spectroscopy (NEXAFS) in the soft X-ray regime between 284 eV to 1303 eV with a resolving power of up to 1370. Based on a laser-produced plasma source, a pair of identical reflection zone plates and an X-ray CCD camera, the ... Read more >>

Opt Express (Optics express)
[2019, 27(25):36524-36537]

Cited: 0 times

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Adaptation to Host-Specific Bacterial Pathogens Drives Rapid Evolution of a Human Innate Immune Receptor.

Jonas Adrian, Patrizia Bonsignore, Sebastian Hammer, Tancred Frickey, Christof R Hauck,

The selective pressure by infectious agents is a major driving force in the evolution of humans and other mammals. Members of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family serve as receptors for bacterial pathogens of the genera Haemophilus, Helicobacter, Neisseria, and Moraxella, which engage CEACAMs via distinct surface adhesins. While ... Read more >>

Curr Biol (Current biology : CB)
[2019, 29(4):616-630.e5]

Cited: 16 times

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On the Electronic Structure of Cu Chlorophyllin and Its Breakdown Products: A Carbon K-Edge X-ray Absorption Spectroscopy Study.

Katharina Witte, Ioanna Mantouvalou, Rocío Sánchez-de-Armas, Heiko Lokstein, Janina Lebendig-Kuhla, Adrian Jonas, Friedrich Roth, Birgit Kanngießer, Holger Stiel,

Using near-edge X-ray absorption fine structure (NEXAFS) spectroscopy, the carbon backbone of sodium copper chlorophyllin (SCC), a widely used chlorophyll derivative, and its breakdown products are analyzed to elucidate their electronic structure and physicochemical properties. Using various sample preparation methods and complementary spectroscopic methods (including UV/Vis, X-ray photoelectron spectroscopy), a ... Read more >>

J Phys Chem B (The journal of physical chemistry. B)
[2018, 122(6):1846-1851]

Cited: 1 time

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