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Author Aditya Gupta

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How good is artificial intelligence (AI) at solving hairy problems? A review of AI applications in hair restoration and hair disorders.

Aditya K Gupta, Iordanka A Ivanova, Helen J Renaud,

Artificial intelligence (AI) applications in medicine are rapidly evolving. Deep learning diagnostic models that can accurately classify skin lesions have been developed. New AI applications are also starting to emerge in the hair restoration field. Our objective was to review the current and future clinical applications of AI in hair ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2021, :e14811]

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Exploring the Therapeutic Potential of the Bioinspired Reconstituted High Density Lipoprotein Nanostructures.

Aditya Gupta, Reena Sharma, Kaushik Kuche, Sanyog Jain,

Lipoproteins are endogenously present nanocarriers and are the primary commuters of cholesterol within the body. Among lipoproteins, HDL inherits size in nm range with anti-oxidant potential and receptor affinity which makes them an attractive candidate for drug delivery. Hence, in this review, we glance across the biosynthesis, architecture, and methods ... Read more >>

Int J Pharm (International journal of pharmaceutics)
[2021, :120272]

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Shorter Duration of Antibiotics in Low-Risk Febrile Neutropenia in Children with Malignancy.

Jagdish Prasad Meena, Aditya Kumar Gupta,

Indian J Pediatr (Indian journal of pediatrics)
[2021, :]

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The Growing Problem of Antifungal Resistance in Onychomycosis and Other Superficial Mycoses.

Aditya K Gupta, Helen J Renaud, Emma M Quinlan, Neil H Shear, Vincent Piguet,

Superficial mycoses are becoming increasingly resistant to current antifungal medications. As alternative therapeutic options are limited, the increasing frequency of reports of antifungal resistance is alarming. This epidemic parallels the rise of antibiotic resistance; however, the significance of this problem has yet to gain global attention. Here, we discuss the ... Read more >>

Am J Clin Dermatol (American journal of clinical dermatology)
[2020, :]

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Robust and sustained antibody response to SARS-CoV-2 in a child pre and post autologous hematopoietic stem cell transplant.

Aditya Kumar Gupta, Mohanraj Ramachandran, Jagdish Prasad Meena, Tanima Dwivedi, Urvashi Singh, Ritu Gupta, Rachna Seth,

Pediatr Blood Cancer (Pediatric blood & cancer)
[2020, :e28848]

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Molecular phylogenetics reveals a species complex pattern of closely related members of genus Thelohanellus (Cnidaria: Myxosporea) from the Indian subcontinent.

Harpreet Kaur, Aditya Gupta, Rajni Attri,

Out of the total 2600 myxozoan species reported so far, Thelohanellus Kudo, 1933 is the second most prevalent genus comprising of about 150 species after Myxobolus Butschli, 1882 infecting both freshwater and marine fishes. In general, these are mostly histozoic (within the tissues) and sometimes coelozoic (in body cavities). The ... Read more >>

Microb Pathog (Microbial pathogenesis)
[2020, 150:104690]

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Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency.

Sujal Ghosh, Sevgi Köstel Bal, Emily S J Edwards, Bethany Pillay, Raúl Jiménez Heredia, Funda Erol Cipe, Geetha Rao, Elisabeth Salzer, Samaneh Zoghi, Hassan Abolhassani, Tooba Momen, Emma Gostick, David A Price, Yu Zhang, Andrew J Oler, Claudia Gonzaga-Jauregui, Baran Erman, Ayse Metin, Inci Ilhan, Sule Haskologlu, Candan Islamoglu, Kubra Baskin, Serdar Ceylaner, Ebru Yilmaz, Ekrem Unal, Musa Karakukcu, Dagmar Berghuis, Theresa Cole, Aditya K Gupta, Fabian Hauck, Hubert Kogler, Andy I M Hoepelman, Safa Baris, Elif Karakoc-Aydiner, Ahmet Ozen, Leo Kager, Dirk Holzinger, Michael Paulussen, Renate Krüger, Roland Meisel, Prasad T Oommen, Emma Morris, Benedicte Neven, Austen Worth, Joris van Montfrans, Pieter L A Fraaij, Sharon Choo, Figen Dogu, E Graham Davies, Siobhan Burns, Gregor Dückers, Ruy Perez Becker, Horst von Bernuth, Sylvain Latour, Maura Faraci, Marco Gattorno, Helen C Su, Qiang Pan-Hammarström, Lennart Hammarström, Michael J Lenardo, Cindy S Ma, Tim Niehues, Asghar Aghamohammadi, Nima Rezaei, Aydan Ikinciogullari, Stuart G Tangye, Arjan C Lankester, Kaan Boztug,

Biallelic mutations in the genes encoding CD27 or its ligand CD70 underlie inborn errors of immunity (IEIs) characterized predominantly by Epstein-Barr virus (EBV)-associated immune dysregulation, such as chronic viremia, severe infectious mononucleosis, hemophagocytic lymphohistiocytosis (HLH), lymphoproliferation, and malignancy. A comprehensive understanding of the natural history, immune characteristics, and transplant outcomes ... Read more >>

Blood (Blood)
[2020, 136(23):2638-2655]

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Amzeeq (minocycline foam 4%) for topical treatment of acne vulgaris.

Aditya K Gupta, Anthony Bruce, Kimberly Dawn Vincent, William Abramovits,

Skinmed (Skinmed)
[2020, 18(6):354-357]

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Cytotoxic T-lymphocyte elicited therapeutic vaccine candidate targeting cancer against MAGE-A11 carcinogenic protein.

Neeraj Kumar, Damini Sood, Aditya Gupta, Niraj Kumar Jha, Pallavi Jain, Ramesh Chandra,

Immunotherapy is a breakthrough approach for cancer treatment and prevention. By exploiting the fact that cancer cells have overexpression of tumor antigens responsible for its growth and progression, which can be identified and removed by boosting the immune system. In silico techniques have provided efficient ways for developing preventive measures ... Read more >>

Biosci Rep (Bioscience reports)
[2020, 40(12):]

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Follicular Unit Excision Punches and Devices.

Aditya K Gupta, Robin P Love, Robert H True, James A Harris,

<h4>Background</h4>Follicular unit excision (FUE) is used to harvest follicular units for hair transplantation using trephine punches. The characteristics of FUE punches can impact the success of this technique; thus, many innovative punch designs and devices have been developed. With many options available, it can be difficult for the hair restoration ... Read more >>

Dermatol Surg (Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.])
[2020, 46(12):1705-1711]

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Hair loss treatment information on Facebook: Content analysis and comparison with other online sources.

Aditya K Gupta, Iordanka A Ivanova,

<h4>Background</h4>Facebook is the biggest online social networking platform, and it is being utilized by patients for peer support as well as to explore treatment options. Hair loss patients can experience negative psychological effects and are likely to turn to social networking platforms for support and treatment information.<h4>Aims</h4>To evaluate the type ... Read more >>

J Cosmet Dermatol (Journal of cosmetic dermatology)
[2021, 20(2):577-583]

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Outcomes of Febrile Neutropenia in Children With Cancer Managed on an Outpatient Basis: A Report From Tertiary Care Hospital From a Resource-limited Setting.

Jagdish P Meena, Aditya K Gupta, Rachna Seth,

In low-risk febrile neutropenia (FN) patients, outpatient management is now an accepted treatment, but there is a scarcity of data on high-risk patients. The aim of our study was to describe the outcome of FN treated primarily in an outpatient setting on the basis of the severity of illness at ... Read more >>

J Pediatr Hematol Oncol (Journal of pediatric hematology/oncology)
[2020, 42(8):467-473]

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A review of the clinical applications of ketamine in pediatric oncology.

Satya Prakash, Aditya Kumar Gupta, Jagdish Prasad Meena, Rachna Seth,

Ketamine is a dissociative anesthetic agent with excellent analgesic properties and a favorable safety profile. The feasibility and efficacy of various routes of administration have been established, including intravenous (IV), intramuscular (IM), oral, intranasal, rectal, and transdermal routes. The advent of newer anesthetic agents has led to a decline in ... Read more >>

Pediatr Blood Cancer (Pediatric blood & cancer)
[2021, 68(1):e28785]

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Changing trends in surgical hair restoration: Use of Google Trends and the ISHRS practice census survey.

Aditya K Gupta, Emma M Quinlan,

<h4>Background</h4>Hair loss affects most people at some point in their lifetime, causing anxiety and decreased self-esteem. There are multiple surgical and nonsurgical treatments available, with the surgical options having greater and longer-lasting effects. Such treatments have evolved over time with advances in technology and research, with numerous patients researching these ... Read more >>

J Cosmet Dermatol (Journal of cosmetic dermatology)
[2020, 19(11):2974-2981]

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A rare presentation of Erdheim Chester disease in a pediatric patient subsequently cured on the LCH III protocol.

Aditya Kumar Gupta, Abdul Wajid M, Jagdish P Meena, Sreedharan T ArunRaj, Asit Mridha, Priyanka Naranje, Rakesh Kumar, Rachna Seth,

<h4>Background</h4>Erdheim Chester disease (ECD) is very rare in pediatrics with no standard treatment guidelines. Here we present the case of a pediatric ECD patient who was cured with a Langerhan cell histiocytosis (LCH) directed chemotherapy protocol.<h4>Aim</h4>The aim of the report was to publish this rare presentation of ECD in pediatrics ... Read more >>

Cancer Rep (Hoboken) (Cancer reports (Hoboken, N.J.))
[2020, :e1304]

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High prevalence of mixed infections in global onychomycosis.

Aditya K Gupta, Valeria B A Taborda, Paulo R O Taborda, Avner Shemer, Richard C Summerbell, Kerry-Ann Nakrieko,

Onychomycosis is estimated at a prevalence of 10% worldwide with the infecting organism most commonly Trichophyton rubrum (T. rubrum). Traditional culture identification of causative organisms has inherent risks of overestimating dermatophytes, like T. rubrum, by inhibiting the growth of possible nondermatophyte mould (NDM) environmental contaminants which could be causative agents. ... Read more >>

PLoS One (PloS one)
[2020, 15(9):e0239648]

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Factors influencing the effect of photobiomodulation in the treatment of androgenetic alopecia: A systematic review and analyses of summary-level data.

Aditya K Gupta, Mary A Bamimore,

Low-level laser therapy (LLLT) is used to treat androgenetic alopecia (AGA). The therapeutic effect of LLLT on AGA has been evaluated; however, there is a paucity of studies that investigated device- and usage-related factors that may influence the effect of LLLT on hair regrowth. The literature was systematically searched to ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2020, 33(6):e14191]

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Analysis of YouTube hair loss treatment information: What makes for engaging content?

Aditya K Gupta, Iordanka A Ivanova,

Patients are increasingly seeking effective hair loss treatments. The internet and social media are popular sources of health information, but the quality and reliability of the content available to patients is highly variable. More than two thirds of American adults reported using YouTube in 2019. We investigated public interest in ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2020, 33(6):e14244]

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A network meta-analysis on the efficacy and safety of monotherapies for tinea capitis, and an assessment of evidence quality.

Aditya K Gupta, Mary A Bamimore, Helen J Renaud, Neil H Shear, Vincent Piguet,

Various monotherapies exist for tinea capitis; however, their relative efficacies have never been determined using a statistical approach which compares treatments' efficacy simultaneously. The goal of this study was to determine the relative efficacy (mycologic and complete cure rates) of monotherapies for the treatment of tinea capitis. On October 5, ... Read more >>

Pediatr Dermatol (Pediatric dermatology)
[2020, 37(6):1014-1022]

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The shifting preferences of patients and physicians in nonsurgical hair loss treatment.

Aditya K Gupta, Emma M Quinlan, Ken L Williams,

<h4>Background</h4>There are multiple etiologies for hair thinning and loss, including genetic, hormonal, immune, scaring, and infectious. Hair loss treatment involves both surgical intervention and nonsurgical therapies such as pharmaceuticals, haircare products, vitamins, and low-level laser therapy (LLLT). While pharmaceuticals have been extensively researched, the efficacy of other therapies remains inconclusive. ... Read more >>

J Cosmet Dermatol (Journal of cosmetic dermatology)
[2020, :]

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Platelet-rich plasma for androgenetic alopecia: Efficacy differences between men and women.

Aditya K Gupta, Helen J Renaud, Mary Bamimore,

Platelet-rich plasma (PRP) may be effective for treating androgenetic alopecia (AGA); albeit, its efficacy in men and women is still debated. We conducted meta-analyses to determine PRP efficacy in men and women separately. Studies were identified after systematically searching for trials that investigated PRP monotherapy for AGA in men and ... Read more >>

Dermatol Ther (Dermatologic therapy)
[2020, 33(6):e14143]

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Safety, Pharmacokinetics, and Efficacy of Efinaconazole 10% Topical Solution for Onychomycosis Treatment in Pediatric Patients.

Lawrence F Eichenfield, Boni Elewski, Jeffrey L Sugarman, Ted Rosen, Tracey C Vlahovic, Aditya K Gupta, Linda Stein Gold, Radhakrishnan Pillai, Eric Guenin,

<h4>Background</h4>Pediatric onychomycosis management is challenging as there are limited treatment options. The objective of this study was to evaluate efinaconazole 10% topical solution in children with onychomycosis.<h4>Methods</h4>This phase 4, multicenter, open-label study (NCT02812771) evaluated safety, pharmacokinetics (PK), and efficacy of efinaconazole 10% topical solution in pediatric participants (6-16 years). Efinaconazole ... Read more >>

J Drugs Dermatol (Journal of drugs in dermatology : JDD)
[2020, 19(9):867-872]

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Reasons for missed chemotherapy appointments in retinoblastoma patients undergoing chemotherapy: A report from a Tertiary Care Hospital from India.

Aditya Kumar Gupta, Jagdish Prasad Meena, Rachna Seth,

<h4>Background</h4>Delays in chemotherapy due to missed-appointments can lead to sub-optimal outcomes in any cancer. Missed appointments or delayed follow up are an important concern in the treatment of pediatric cancers as it compromises the patient's health and overall outcomes.<h4>Aim</h4>This study was conducted to understand the reasons responsible for missed-appointments in ... Read more >>

Cancer Rep (Hoboken) (Cancer reports (Hoboken, N.J.))
[2020, 3(6):e1279]

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Communicating Calf Swelling in Systemic-Onset Juvenile Idiopathic Arthritis.

Dulasi Durga K, Aditya Gupta, Devasenathipathy Kandasamy, Narendra Kumar Bagri,

J Clin Rheumatol (Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases)
[2020, :]

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Onychomycosis in children - review on treatment and management strategies.

Aditya K Gupta, Maanasa Venkataraman, Neil H Shear, Vincent Piguet,

BACKGROUND:Onychomycosis is an uncommon condition in children with increasing global prevalence. Health practitioners should confirm the diagnosis through mycology examination and examine family members of affected individuals for onychomycosis and tinea pedis. OBJECTIVE:To comprehensively summarize the treatment and management strategies for pediatric onychomycosis. METHODS:We performed a comprehensive literature search in ... Read more >>

J Dermatolog Treat (The Journal of dermatological treatment)
[2020, :1-12]

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