Full Text Journal Articles by
Author Adam Brouwer

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Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020.

Nicola S Lewis, Ashley C Banyard, Elliot Whittard, Talgat Karibayev, Thamer Al Kafagi, Ilya Chvala, Alex Byrne, Saduakassova Meruyert Akberovna, Jacqueline King, Timm Harder, Christian Grund, Steve Essen, Scott M Reid, Adam Brouwer, Nikolay G Zinyakov, Azimkhan Tegzhanov, Victor Irza, Anne Pohlmann, Martin Beer, Ron A M Fouchier, Sultanov Akhmetzhan Akievich, Ian H Brown,

Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected maintenance of H5N8, likely in galliform poultry since 2017/18 and both H5N5 and H5N1. ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):148-151]

Cited: 9 times

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Regional Transmission and Reassortment of 2.3.4.4b Highly Pathogenic Avian Influenza (HPAI) Viruses in Bulgarian Poultry 2017/18.

Divya Venkatesh, Adam Brouwer, Gabriela Goujgoulova, Richard Ellis, James Seekings, Ian H Brown, Nicola S Lewis,

Between 2017 and 2018, several farms across Bulgaria reported outbreaks of H5 highly-pathogenic avian influenza (HPAI) viruses. In this study we used genomic and traditional epidemiological analyses to trace the origin and subsequent spread of these outbreaks within Bulgaria. Both methods indicate two separate incursions, one restricted to the northeastern ... Read more >>

Viruses (Viruses)
[2020, 12(6):]

Cited: 4 times

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Regional transmission and reassortment of 2.3.4.4b highly pathogenic avian influenza (HPAI) viruses in Bulgarian poultry 2017/18

Divya Venkatesh, Adam Brouwer, Richard Ellis, Gabriela Goujgoulova, James Seekings, Ian Brown, Nicola Lewis,

Between 2017 and 2018, several farms across Bulgaria reported outbreaks of H5 HPAI viruses. In this study we use genomic and traditional epidemiological analyses to trace the origin and subsequent spread of these outbreaks within Bulgaria. Both methods indicate two separate incursions, one restricted to the North-Eastern region of Dobrich, ... Read more >>

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Annual Report on surveillance for avian influenza in poultry and wild birds in Member States of the European Union in 2018.

, Adam Brouwer, Jose Gonzales, Adeline Huneau, Paolo Mulatti, Thijs Kuiken, Christoph Staubach, Arjan Stegeman, Sotiria-Eleni Antoniou, Francesca Baldinelli, Yves Van der Stede, Inma Aznar,

Avian influenza (AI) is a viral infectious disease that affects all species of domestic and wild birds. The viruses causing this disease can be of high (HPAI) or low (LPAI) pathogenicity and represent a continuous threat to poultry in Europe. Council Directive 2005/94/EC requests EU Member States (MSs) to carry ... Read more >>

EFSA J (EFSA journal. European Food Safety Authority)
[2019, 17(12):e05945]

Cited: 5 times

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Quantifying the spatial risk of Avian Influenza introduction into British poultry by wild birds.

Andrew Hill, Simon Gillings, Alexander Berriman, Adam Brouwer, Andrew C Breed, Lucy Snow, Adam Ashton, Charles Byrne, Richard M Irvine,

The transmission of pathogens across the interface between wildlife and livestock presents a challenge to the development of effective surveillance and control measures. Wild birds, especially waterbirds such as the Anseriformes and Charadriiformes are considered to be the natural hosts of Avian Influenza (AI), and are presumed to pose one ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):19973]

Cited: 1 time

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Assessing effects from four years of industry-led badger culling in England on the incidence of bovine tuberculosis in cattle, 2013-2017.

Sara H Downs, Alison Prosser, Adam Ashton, Stuart Ashfield, Lucy A Brunton, Adam Brouwer, Paul Upton, Andrew Robertson, Christl A Donnelly, Jessica E Parry,

The objective was to measure the association between badger culling and bovine tuberculosis (TB) incidents in cattle herds in three areas of England between 2013-2017 (Gloucestershire and Somerset) and 2015-2017 (Dorset). Farming industry-selected licensed culling areas were matched to comparison areas. A TB incident was detection of new Mycobacterium bovis ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):14666]

Cited: 6 times

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Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe.

Pablo Alarcon, Adam Brouwer, Divya Venkatesh, Daisy Duncan, Chrysostomos I Dovas, George Georgiades, Isabella Monne, Alice Fusaro, Adam Dan, Krzysztof Śmietanka, Vassilios Ragias, Andrew C Breed, Taxiarchis Chassalevris, Gabriela Goujgoulova, Charlotte Kristiane Hjulsager, Eoin Ryan, Azucena Sánchez, Eric Niqueux, Niina Tammiranta, Siamak Zohari, David A Stroud, Vladimir Savić, Nicola S Lewis, Ian H Brown,

We analyzed the highly pathogenic avian influenza (HPAI) H5 epizootic of 2016-17 in Europe by epidemiologic and genetic characteristics and compared it with 2 previous epizootics caused by the same H5 Guangdong lineage. The 2016-17 epizootic was the largest in Europe by number of countries and farms affected and greatest ... Read more >>

Emerg Infect Dis (Emerging infectious diseases)
[2018, 24(12):2270-2283]

Cited: 17 times

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Avian influenza overview August - November 2018.

, , , Cornelia Adlhoch, Adam Brouwer, Thijs Kuiken, Aleksandra Miteva, Paolo Mulatti, Krzysztof Smietanka, Christoph Staubach, Andrey Gogin, Irene Muñoz Guajardo, Francesca Baldinelli,

Between 16 August and 15 November 2018, 14 highly pathogenic avian influenza (HPAI) A(H5N8) outbreaks in poultry establishments in Bulgaria and seven HPAI A(H5N6) outbreaks, one in captive birds in Germany and six in wild birds in Denmark and the Netherlands were reported in the European Union (EU). No human ... Read more >>

EFSA J (EFSA journal. European Food Safety Authority)
[2018, 16(12):e05573]

Cited: 2 times

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Reporting Avian Influenza surveillance.

, Adam Brouwer, Adeline Huneau, Thijs Kuiken, Christoph Staubach, Arjan Stegeman, Francesca Baldinelli, Frank Verdonck, Inma Aznar,

Avian influenza viruses infect domestic poultry and wild birds as well as humans. In poultry, depending on whether these viruses are of high pathogenicity (HPAI) or low pathogenicity (LPAI), the infection can cause different clinical signs, with HPAI causing high mortality in poultry flocks. In order to ensure early detection ... Read more >>

EFSA J (EFSA journal. European Food Safety Authority)
[2018, 16(11):e05493]

Cited: 0 times

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Avian influenza overview February - May 2018.

, , , Cornelia Adlhoch, Adam Brouwer, Thijs Kuiken, Paolo Mulatti, Krzysztof Smietanka, Christoph Staubach, Irene Muñoz Guajardo, Frank Verdonck, Laura Amato, Francesca Baldinelli,

Between 16 February and 15 May 2018, three highly pathogenic avian influenza (HPAI) A(H5N6) and 11 HPAI A(H5N8) outbreaks in poultry holdings, one HPAI A(H5N6) and one HPAI A(H5N8) outbreak in captive birds, and 55 HPAI A(H5N6) wild bird events were reported in Europe. There is no evidence to date ... Read more >>

EFSA J (EFSA journal. European Food Safety Authority)
[2018, 16(6):e05358]

Cited: 2 times

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Avian influenza overview November 2017 - February 2018.

, , , Cornelia Adlhoch, Adam Brouwer, Thijs Kuiken, Paolo Mulatti, Krzysztof Smietanka, Christoph Staubach, Preben Willeberg, Federica Barrucci, Frank Verdonck, Laura Amato, Francesca Baldinelli,

Between 16 November 2017 and 15 February 2018, one highly pathogenic avian influenza (HPAI) A(H5N6) and five HPAI A(H5N8) outbreaks in poultry holdings, two HPAI A(H5N6) outbreaks in captive birds and 22 HPAI A(H5N6) wild bird events were reported within Europe. There is a lower incursion of HPAI A(H5N6) in ... Read more >>

EFSA J (EFSA journal. European Food Safety Authority)
[2018, 16(3):e05240]

Cited: 1 time

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Avian influenza.

, Simon More, Dominique Bicout, Anette Bøtner, Andrew Butterworth, Paolo Calistri, Klaus Depner, Sandra Edwards, Bruno Garin-Bastuji, Margaret Good, Christian Gortázar Schmidt, Virginie Michel, Miguel Angel Miranda, Søren Saxmose Nielsen, Mohan Raj, Liisa Sihvonen, Hans Spoolder, Hans-Hermann Thulke, Antonio Velarde, Preben Willeberg, Christoph Winckler, Andrew Breed, Adam Brouwer, Matthieu Guillemain, Timm Harder, Isabella Monne, Helen Roberts, Francesca Baldinelli, Federica Barrucci, Chiara Fabris, Laura Martino, Olaf Mosbach-Schulz, Frank Verdonck, Joana Morgado, Jan Arend Stegeman,

Previous introductions of highly pathogenic avian influenza virus (HPAIV) to the EU were most likely via migratory wild birds. A mathematical model has been developed which indicated that virus amplification and spread may take place when wild bird populations of sufficient size within EU become infected. Low pathogenic avian influenza ... Read more >>

EFSA J (EFSA journal. European Food Safety Authority)
[2017, 15(10):e04991]

Cited: 6 times

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Attribution of human VTEC O157 infection from meat products: a quantitative risk assessment approach.

Rowena D Kosmider, Pádraig Nally, Robin R L Simons, Adam Brouwer, Susan Cheung, Emma L Snary, Marion Wooldridge,

To address the risk posed to human health by the consumption of VTEC O157 within contaminated pork, lamb, and beef products within Great Britain, a quantitative risk assessment model has been developed. This model aims to simulate the prevalence and amount of VTEC O157 in different meat products at consumption ... Read more >>

Risk Anal (Risk analysis : an official publication of the Society for Risk Analysis)
[2010, 30(5):753-765]

Cited: 6 times

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Analysis of the antigen combining site: correlations between length and sequence composition of the hypervariable loops and the nature of the antigen.

Abigail V J Collis, Adam P Brouwer, Andrew C R Martin,

It has long been suggested that the overall shape of the antigen combining site (ACS) of antibodies is correlated with the nature of the antigen. For example, deep pockets are characteristic of antibodies that bind haptens, grooves indicate peptide binders, while antibodies that bind to proteins have relatively flat combining ... Read more >>

J Mol Biol (Journal of molecular biology)
[2003, 325(2):337-354]

Cited: 152 times

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