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Author A Parodi

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THE HISTORY OF SYPHILIS IN THE XVI CENTURY AND THE PIVOTAL ROLE OF LUIGI LUIGINI IN THE RENAISSANCE

Mariano Martini, Emanuele Armocida, Luca Lo Basso, Emiliano Beri, Nicola Luigi Bragazzi, Alessandra Parodi,

Syphilis is the prime example of a "new disease" which triggered a transnational (European) discussion among physicians. It appeared between the end of the Middle Ages and the beginning of the Modern Times (at the beginning of the sixteenth century), a time in which medicine was changing from a dogmatic ... Read more >>

Acta Med Hist Adriat (Acta medico-historica adriatica : AMHA)
[2021, 18(2):375-397]

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Correction to: Venous thromboembolism and COVID-19: a single center experience from an academic tertiary referral hospital of Northern Italy.

Federica Melazzini, Marta Colaneri, Federica Fumoso, Giulia Freddi, Marco Vincenzo Lenti, Teresa Chiara Pieri, Davide Piloni, Patrizia Noris, Carla Pieresca, Paola Stefania Preti, Mariaconcetta Russo, Angelo Corsico, Guido Tavazzi, Fausto Baldanti, Antonio Triarico, Francesco Mojoli, Raffaele Bruno, Antonio Di Sabatino, ,

Intern Emerg Med (Internal and emergency medicine)
[2021, 16(5):1153]

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Updates on lymphogranuloma venereum.

G Ciccarese, F Drago, A Rebora, A Parodi,

J Eur Acad Dermatol Venereol (Journal of the European Academy of Dermatology and Venereology : JEADV)
[2021, 35(8):1606-1607]

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Efficacy and safety of Dimethylfumarate in elderly psoriasis patients: a multicentric Italian study.

F Ricceri, F Bardazzi, G Buggiani, M Burlando, E Campione, M Corazza, A Cuccia, P Dapavo, F Filippi, L Zichichi, A Parodi, F Prignano,

The number of psoriatic elderly patients is steadily increasing in the Western world, nevertheless they are frequently excluded from clinical trials and described as a high-risk group for adverse events.We conducted a retrospective multicentric study of DMF use in elderly (>65 years) psoriatic patients. DMF efficacy was evaluated up to ... Read more >>

J Dermatolog Treat (The Journal of dermatological treatment)
[2021, :1-11]

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Pruritic Erythematous Macules in a Patient with Systemic Sarcoidosis: A Quiz.

Astrid Herzum, Mattia Fabio Molle, Emanuele Cozzani, Martina Burlando, Pietro Paolo Tavilla, Claudia Micalizzi, Ilaria Trave, Aurora Parodi,

Acta Derm Venereol (Acta dermato-venereologica)
[2021, :]

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Correction to: Comorbidities and treatment patterns in adult patients with atopic dermatitis: results from a nationwide multicenter study.

A Campanati, T Bianchelli, R Gesuita, C Foti, G Malara, G Micali, P Amerio, F Rongioletti, M Corazza, A Patrizi, K Peris, N Pimpinelli, A Parodi, M C Fargnoli, S P Cannavo, P Pigatto, G Pellacani, S M Ferrucci, G Argenziano, F Cusano, G Fabbrocini, L Stingeni, M C Potenza, M Romanelli, L Bianchi, A Offidani, ,

Arch Dermatol Res (Archives of dermatological research)
[2021, :]

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Cathepsin D-Managing the Delicate Balance.

Olja Mijanovic, Anastasiia I Petushkova, Ana Brankovic, Boris Turk, Anna B Solovieva, Angelina I Nikitkina, Sergey Bolevich, Peter S Timashev, Alessandro Parodi, Andrey A Zamyatnin,

Lysosomal proteases play a crucial role in maintaining cell homeostasis. Human cathepsin D manages protein turnover degrading misfolded and aggregated proteins and favors apoptosis in the case of proteostasis disruption. However, when cathepsin D regulation is affected, it can contribute to numerous disorders. The down-regulation of human cathepsin D is ... Read more >>

Pharmaceutics (Pharmaceutics)
[2021, 13(6):]

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Comorbidities and treatment patterns in adult patients with atopic dermatitis: results from a nationwide multicenter study.

A Campanati, T Bianchelli, R Gesuita, C Foti, G Malara, G Micali, P Amerio, F Rongioletti, M Corazza, A Patrizi, K Peris, N Pimpinelli, A Parodi, M C Fargnoli, S P Cannavo, P Pigatto, G Pellacani, S M Ferrucci, G Argenziano, F Cusano, G Fabbrocini, L Stingeni, M C Potenza, M Romanelli, L Bianchi, A Offidani, ,

Adult atopic dermatitis (adult AD) is a systemic inflammatory disorder, whose relationship with immune-allergic and metabolic comorbidities is not well established yet. Moreover, treatment of mild-to-moderate and severe atopic dermatitis needs standardization among clinicians. The aim of this study was to evaluate the distribution of comorbidities, including metabolic abnormalities, rhinitis, ... Read more >>

Arch Dermatol Res (Archives of dermatological research)
[2021, :]

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Atypical and Rare Forms of Cutaneous Lupus Erythematosus: The Importance of the Diagnosis for the Best Management of Patients.

Astrid Herzum, Giulia Gasparini, Emanuele Cozzani, Martina Burlando, Aurora Parodi,

Lupus erythematosus (LE) is an autoimmune disease with a wide range of clinical and cutaneous manifestations. Along with the well-known typical cutaneous manifestations of LE, some cutaneous manifestations are rarer, but still characteristic, enabling the dermatologist and the general practitioner who know them to suspect cutaneous LE (CLE) and investigate ... Read more >>

Dermatology (Dermatology (Basel, Switzerland))
[2021, :1-10]

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Correlation Between Skin and Affected Organs in 52 Sclerodermic Patients Followed in a Diseases Management Team: Development of a Risk Prediction Model of Organ-Specific Complications.

Emanuele Cozzani, Andrea Muracchioli, Giuseppe Murdaca, Mirko Beccalli, Simone Caprioli, Patrizia Zentilin, Pietro Ameri, Marco Grosso, Rodolfo Russo, Luca Carmisciano, Aurora Parodi,

<h4>Objective</h4>To identify the existence of a correlation among the various organs affected, focusing primarily on immuno-dermatological aspects, and to create a risk prediction model of organ-specific complications.<h4>Material and methods</h4>Fifty-two patients with stable scleroderma, followed between 2015 and 2019, were investigated through an extensive multidisciplinary evaluation in the last year.<h4>Results</h4>Patients with ... Read more >>

Front Immunol (Frontiers in immunology)
[2021, 12:588753]

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Considerations on SARS-Cov-2 vaccines in patients with autoimmune blistering diseases.

Emanuele Cozzani, Giulia Gasparini, Laura Sticchi, Roberto Russo, Giancarlo Icardi, Aurora Parodi,

Eur J Dermatol (European journal of dermatology : EJD)
[2021, 31(3):415-417]

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Treatment of moderate-to-severe plaque psoriasis with tildrakizumab in the real-life setting.

Martina Burlando, Riccardo Castelli, Emanuele Cozzani, Aurora Parodi,

<h4>Background</h4>Tildrakizumab is a high-affinity, humanized IgG1κ monoclonal antibody targeting the p19 subunit of IL-23, which is a key regulatory cytokine in psoriasis. Based on evidence from clinical trials, tildrakizumab is approved for the treatment of moderate-to-severe plaque psoriasis in patients eligible for systemic therapy.<h4>Methods</h4>We report our clinical experience with 26 ... Read more >>

Drugs Context (Drugs in context)
[2021, 10:]

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[The ``One health'' concept: reality and future prospect].

A L Parodi,

Bull Acad Natl Med (Bulletin de l'Academie nationale de medecine)
[2021, 205(7):659-661]

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Giant nevus comedonicus of the entire lower left limb protecting from the associated bullous pemphigoid: A hypothetical role of NEK9 mutation?

Astrid Herzum, Emanuele Cozzani, Claudia Micalizzi, Roberto Russo, Riccardo Castelli, Aurora Parodi,

We present the case of a 92-year-old woman, with bullous pemphigoid (BP) and a concomitant nevus comedonicus (NC) presenting as an asymptomatic, linear lesion of the entire lower left limb, formed by multiple comedones. Dermoscopy of the NC and histopathology confirmed the clinical and dermoscopic suspect of giant congenital nevus ... Read more >>

J Dermatol (The Journal of dermatology)
[2021, :]

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Dermoscopy of papulopustular rosacea and comparison of dermoscopic features in patients with or without concomitant Demodex folliculorum.

I Trave, C Micalizzi, G Gasparini, E Cozzani, A Parodi,

<h4>Background</h4>Dermoscopic findings of papulopustular rosacea include follicular plugs, white scales and follicle dilatation. Demodex tails and Demodex follicular openings are dermoscopic indicators mainly found in primary demodicosis and, less frequently, in rosacea.<h4>Aim</h4>The aim of this study was to describe the dermoscopic features of papulopustular rosacea and investigate the differential dermoscopic ... Read more >>

Clin Exp Dermatol (Clinical and experimental dermatology)
[2021, :]

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Consensus on the place in therapy of biologics in the treatment of patients with chronic plaque psoriasis.

Martina Burlando, Manuela Baldari, Alexandra M Brunasso Vernetti, Giuseppe Cannata, Cesare Massone, Andrea Pestarino, Daniela Stradini, Aurora Parodi,

Ital J Dermatol Venerol (Italian journal of dermatology and venereology)
[2021, :]

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Development of Exhaustion and Acquisition of Regulatory Function by Infiltrating CD8+CD28- T Lymphocytes Dictate Clinical Outcome in Head and Neck Cancer.

Daniela Fenoglio, Liliana Belgioia, Alessia Parodi, Francesco Missale, Almalina Bacigalupo, Alison Tarke, Fabiola Incandela, Simone Negrini, Stefania Vecchio, Tiziana Altosole, Sara Vlah, Giuseppina Astone, Francesca Costabile, Alessandro Ascoli, Francesca Ferrera, Guido Schenone, Raffaele De Palma, Alessio Signori, Giorgio Peretti, Renzo Corvò, Gilberto Filaci,

Head and neck squamous cell carcinoma (HNSCC) has a poor clinical outcome despite the presence of a rich CD8+ T cell tumor infiltrate in the majority of patients. This may be due to alterations of tumor infiltrating CD8+ T cells. Here, we performed a characterization of HNSCC infiltrating CD8+ T ... Read more >>

Cancers (Basel) (Cancers)
[2021, 13(9):]

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Correction to: Anemia in patients with Covid-19: pathogenesis and clinical significance.

Gaetano Bergamaschi, Federica Borrelli de Andreis, Nicola Aronico, Marco Vincenzo Lenti, Chiara Barteselli, Stefania Merli, Ivan Pellegrino, Luigi Coppola, Elisa Maria Cremonte, Gabriele Croce, Francesco Mordà, Francesco Lapia, Sara Ferrari, Alessia Ballesio, Alessandro Parodi, Francesca Calabretta, Maria Giovanna Ferrari, Federica Fumoso, Antonella Gentile, Federica Melazzini, Antonio Di Sabatino, ,

Clin Exp Med (Clinical and experimental medicine)
[2021, 21(2):247]

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Characterization of T lymphocytes in severe COVID-19 patients.

Daniela Fenoglio, Chiara Dentone, Alessia Parodi, Antonio Di Biagio, Federica Bozzano, Antonio Vena, Marina Fabbi, Francesca Ferrera, Tiziana Altosole, Bianca Bruzzone, Mauro Giacomini, Paolo Pelosi, Andrea De Maria, Matteo Bassetti, Raffaele De Palma, Gilberto Filaci,

In this observational study, 13 patients with severe COVID-19 and 10 healthy controls were enrolled. The data concerning the analysis of circulating T cells show that, in severe COVID-19 patients, the expansion of these cell compartments is prone to induce antibody response, inflammation (CCR4+ and CCR6+ TFH) and regulation (CD8+ Treg). This pathogenic ... Read more >>

J Med Virol (Journal of medical virology)
[2021, 93(9):5608-5613]

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Ulcer of the penis due to mycoplasma hominis infection: an example of pseudo-chancre.

Francesco Drago, Giulia Ciccarese, Mattia F Molle, Aurora Parodi,

Ital J Dermatol Venerol (Italian journal of dermatology and venereology)
[2021, :]

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Nosological Differences in the Nature of Punctate White Matter Lesions in Preterm Infants.

Mariya Malova, Elena Morelli, Valentina Cardiello, Domenico Tortora, Mariasavina Severino, Maria Grazia Calevo, Alessandro Parodi, Laura Costanza De Angelis, Diego Minghetti, Andrea Rossi, Luca Antonio Ramenghi,

<b>Background:</b> The pathogenesis of punctuate white matter lesions (PWMLs), a mild form of white matter damage observed in preterm infants, is still a matter of debate. Susceptibility-weighted imaging (SWI) allows to differentiate PWMLs based on the presence (SWI+) or absence (SWI-) of hemosiderin, but little is known about the significance ... Read more >>

Front Neurol (Frontiers in neurology)
[2021, 12:657461]

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The longest persistence of viable SARS-CoV-2 with recurrence of viremia and relapsing symptomatic COVID-19 in an immunocompromised patient – a case study

Chiara Sepulcri, Chiara Dentone, Malgorzata Mikulska, Bianca Bruzzone, Alessia Lai, Daniela Fenoglio, Federica Bozzano, Annalisa Bergna, Alessia Parodi, Tiziana Altosole, Emanuele Delfino, Giulia Bartalucci, Andrea Orsi, Antonio Di Biagio, Gianguglielmo Zehender, Filippo Ballerini, Stefano Bonora, Alessandro Sette, Raffaele De Palma, Guido Silvestri, Andrea De Maria, Matteo Bassetti,

Abstract <h4>Background</h4> Immunocompromised patients show prolonged shedding of SARS-CoV-2 in nasopharyngeal swabs. We report a case of a prolonged persistence of viable SARS-CoV-2 associated with clinical relapses of COVID-19 in a patient with mantle-cell lymphoma who underwent treatment with R-BAC (rituximab, bendamustine, cytarabine) with consequent lymphopenia and hypogammaglobulinemia. <h4>Methods</h4> Nasopharyngeal ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2021, :]

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Black soldier fly reared on pig manure: Bioconversion efficiencies, nutrients in the residual material, greenhouse gas and ammonia emissions.

Alejandro Parodi, Walter J J Gerrits, Joop J A Van Loon, Imke J M De Boer, André J A Aarnink, Hannah H E Van Zanten,

There is an increased interest for using insects, such as the black soldier fly, to treat surplus manure and upcycle nutrients into the food system. Understanding the influence that BSFL have on nutrient flows and nutrient losses during manure bioconversion is key for sustainability assessments. Here we quantified and compared ... Read more >>

Waste Manag (Waste management (New York, N.Y.))
[2021, 126:674-683]

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Extensive activation, tissue trafficking, turnover and functional impairment of NK cells in COVID-19 patients at disease onset associates with subsequent disease severity.

Federica Bozzano, Chiara Dentone, Carola Perrone, Antonio Di Biagio, Daniela Fenoglio, Alessia Parodi, Malgorzata Mikulska, Bianca Bruzzone, Daniele Roberto Giacobbe, Antonio Vena, Lucia Taramasso, Laura Nicolini, Nicolò Patroniti, Paolo Pelosi, Angelo Gratarola, Raffaele De Palma, Gilberto Filaci, Matteo Bassetti, Andrea De Maria, ,

The SARS-CoV-2 infection causes severe respiratory involvement (COVID-19) in 5-20% of patients through initial immune derangement, followed by intense cytokine production and vascular leakage. Evidence of immune involvement point to the participation of T, B, and NK cells in the lack of control of virus replication leading to COVID-19. NK ... Read more >>

PLoS Pathog (PLoS pathogens)
[2021, 17(4):e1009448]

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Long Non-Coding PROX1-AS1 Expression Correlates with Renal Cell Carcinoma Metastasis and Aggressiveness.

Magdalena Rudzinska, Karolina H Czarnecka-Chrebelska, Ekaterina B Kuznetsova, Sofya V Maryanchik, Alessandro Parodi, Dmitry O Korolev, Nataliya Potoldykova, Yulia Svetikova, Andrey Z Vinarov, Marina V Nemtsova, Andrey A Zamyatnin,

Long non-coding RNAs (lncRNAs) can be specifically expressed in different tissues and cancers. By controlling the gene expression at the transcriptional and translational levels, lncRNAs have been reported to be involved in tumor growth and metastasis. Recent data demonstrated that multiple lncRNAs have a crucial role in renal cell carcinoma ... Read more >>

Noncoding RNA (Non-coding RNA)
[2021, 7(2):]

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