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Full Text Journal Articles about
Asthma in Older Adults

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Adult outcomes of childhood bronchiectasis.

Dawn Sibanda, Rosalyn Singleton, John Clark, Christine Desnoyers, Ellen Hodges, Gretchen Day, Gregory Redding,

Recent literature has highlighted the importance of transition from paediatric to adult care for children with chronic conditions. Non-cystic fibrosis bronchiectasis is an important cause of respiratory morbidity in low-income countries and in indigenous children from affluent countries; however, there is little information about adult outcomes of childhood bronchiectasis. We ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2020, 79(1):1731059]

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Risk Factors for Acute Exacerbations in Elderly Asthma: What Makes Asthma in Older Adults Distinctive?

Kyoung Hee Sohn, Woo Jung Song, Jong Sook Park, Heung Woo Park, Tae Bum Kim, Choon Sik Park, Sang Heon Cho, ,

PURPOSE:Asthma in the elderly (EA; ≥ 65 years of age) is increasing, adding a heavy socioeconomic burden to the healthcare system. However, little is known about risk factors associated with acute exacerbations in EA patients. The objective of this study was to investigate risk factors for acute exacerbation in EA ... Read more >>

Allergy Asthma Immunol Res (Allergy, asthma & immunology research)
[2020, 12(3):443-453]

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Pre-Transition Readiness in Adolescents and Young Adults with Four Chronic Medical Conditions in South East Nigeria - An African Perspective to Adolescent Transition.

Adaeze C Ayuk, Vivian O Onukwuli, Ijeoma N Obumneme-Anyim, Joy N Eze, Uzoamaka C Akubuilo, Ngozi R Mbanefo, Kenechukwu K Iloh, Osita U Ezenwosu, Israel O Odetunde, Henrietta U Okafor, Ifeoma J Emodi, Tagbo Oguonu,

Introduction:When a child reaches a certain age, he or she moves over to the adult physician. For this to maximally benefit the child, there has to be a process of equipping the child with skills required for taking on more responsibilities. Transitioning involves a process in which the adolescent with ... Read more >>

Adolesc Health Med Ther (Adolescent health, medicine and therapeutics)
[2020, 11:29-38]

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Ketofol performance to reduce postoperative emergence agitation in children undergoing adenotonsillectomy.

Idress Ali, Murad Alahdal, Haifa Xia, Arafa S El Moughrabi, Huang Shiqian, Shanglong Yao,

Background: Emergence agitation is a reformed state of mindfulness, which starts with a sudden form of anesthesia and progresses through the early repossession age. Thus, the purpose of this study is to evaluate 1:3 ketofol performance on children 3-15 years old undergoing adenotonsillectomy.Methods: A total of 60 children aged 3-15 ... Read more >>

Libyan J Med (The Libyan journal of medicine)
[2020, 15(1):1688450]

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Current Bronchodilator Responsiveness Criteria Underestimate Asthma in Older Adults.

Rodrigo S Cavallazzi, Barbara J Polivka, Bryan L Beatty, Demetra E Antimisiaris, Rangaraj K Gopalraj, Rachel A Vickers-Smith, Rodney J Folz,

BACKGROUND:Asthma is common in older adults and is confirmed by demonstration of variable expiratory air-flow limitations, typically evaluated by spirometric assessment of bronchodilator responsiveness. However, many patients with clinically suspected asthma and documented air-flow obstruction do not exhibit a post-bronchodilator response that meets or exceeds current established guidelines. We investigated ... Read more >>

Respir Care (Respiratory care)
[2020, :]

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High healthcare resource utilisation due to pertussis in Australian adults aged 65 years and over.

Robert Neil F Leong, James G Wood, Bette Liu, Peter B McIntyre, Anthony T Newall,

BACKGROUND:In the context of co-morbid illness and increasing age, data on excess morbidity from pertussis in older adults is crucial for immunisation policy but has been largely limited to case-series. METHODS:We designed a matched case-control study nested within a population-based cohort of 267,153 adults aged ≥45 years in New South Wales, ... Read more >>

Vaccine (Vaccine)
[2020, :]

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Correlates of depressive disorders and quality of life among older adults in six low and middle-income countries: WHO country-wide study on global ageing and adult health

Duah Dwomoh, Susan Amuasi, Gabriel Incoom, Alfred Yawson, Emmanuel Asampong, Samuel Bosomprah,

<title>Abstract</title> <p> Background The diagnosis and treatment of Depressive Disorders (DD) remain a challenge in low and middle-income countries (LMICs). Identifying the most important correlate of DD would serve as a guide in the design and implementation of targeted intervention in resource-constrained LMICs. This study determined whether there ... Read more >>

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Dynamics of human monocytes and airway macrophages during healthy aging and after transplant.

Adam J Byrne, Joseph E Powell, Brendan J O'Sullivan, Patricia P Ogger, Ashley Hoffland, James Cook, Katie L Bonner, Richard J Hewitt, Simone Wolf, Poonam Ghai, Simone A Walker, Samuel W Lukowski, Philip L Molyneaux, Sejal Saglani, Daniel C Chambers, Toby M Maher, Clare M Lloyd,

The ontogeny of airway macrophages (AMs) in human lung and their contribution to disease are poorly mapped out. In mice, aging is associated with an increasing proportion of peripherally, as opposed to perinatally derived AMs. We sought to understand AM ontogeny in human lung during healthy aging and after transplant. ... Read more >>

J. Exp. Med. (The Journal of experimental medicine)
[2020, 217(3):]

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Reply to Liu and Zhou: Association of Sex Steroid Hormones with Adult Asthma in the United States, 2013-2016.

Yueh-Ying Han, Erick Forno, Juan C Celedón,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, 201(5):619-620]

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Relationship between chronic diseases and sleep duration among older adults in Ghana.

Jonathan Aseye Nutakor, Baozhen Dai, Alexander Kwame Gavu, Osei-Asibey Antwi,

PURPOSE:Aging increases the prevalence of health problems that are often chronic, resulting in more sleep problems for people with poor health or chronic conditions. Relatively fewer studies have been conducted on the relationship between sleep duration and chronic conditions in Sub-Saharan Africa compared to Western or Asian populations. This study ... Read more >>

Qual Life Res (Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation)
[2020, :]

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Pharmacokinetics and Clinical Pharmacology of Monoclonal Antibodies in Pediatric Patients.

Zaid H Temrikar, Satyendra Suryawanshi, Bernd Meibohm,

Monoclonal antibodies (mAbs) and their derivatives are increasingly used in pediatric pharmacotherapy, and the number of antibody-based drug products with approved pediatric indications is continuously growing. In most instances, pediatric use is being pursued after the efficacy and safety of novel antibody medications have been established in adult indications. The ... Read more >>

Paediatr Drugs (Paediatric drugs)
[2020, 22(2):199-216]

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Adults With Asthma Experience No Increase in Asthma-related Exacerbations When Digital Communication Technology Tools Are Employed to Offset Provider Workload: A Pragmatic Randomized Trial.

Bruce G Bender, Nicole M Wagner, Jo A Shoup, Glenn K Goodrich, Susan M Shetterly, Peter J Cvietusa, Courtney B Anderson, Stan Xu, Debra P Ritzwoller, Cathy Tacinas, Diane K King, Marsha A Raebel,

BACKGROUND:Challenges to health care efficiency are increasingly addressed with the help of digital communication technology tools (DCTs). OBJECTIVE:The objective of this study was to test whether DCT, compared with Usual Care, can reduce health care clinician burden without increasing asthma-related exacerbations among patients with asthma in a large integrated health ... Read more >>

Med Care (Medical care)
[2020, 58(4):352-359]

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Understanding Patient Perspectives on Medication Adherence in Asthma: A Targeted Review of Qualitative Studies.

Suvina Amin, Mena Soliman, Andrew McIvor, Andrew Cave, Claudia Cabrera,

Adherence to asthma medications is generally poor and undermines clinical outcomes. Poor adherence is characterized by underuse of inhaled corticosteroids (ICS), often accompanied by over-reliance on short-acting β2-agonists for symptom relief. To identify drivers of poor medication adherence, a targeted literature search was performed in MEDLINE and EMBASE for articles ... Read more >>

Patient Prefer Adherence (Patient preference and adherence)
[2020, 14:541-551]

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Direct and lost productivity costs associated with avoidable hospital admissions.

João Victor Muniz Rocha, Ana Patrícia Marques, Bruno Moita, Rui Santana,

BACKGROUND:Hospitalizations for ambulatory care sensitive conditions are commonly used to evaluate primary health care performance, as the hospital admission could be avoided if care was timely and adequate. Previous evidence indicates that avoidable hospitalizations carry a substantial direct financial burden in some countries. However, no attention has been given to ... Read more >>

BMC Health Serv Res (BMC health services research)
[2020, 20(1):210]

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Asthma-chronic obstructive pulmonary disease overlap in China: prevalence, associated factors and comorbidities in middle-aged and older adults.

Peige Song, Mingming Zha, Wei Xia, Chunxian Zeng, Yajie Zhu,

Background: Asthma-COPD overlap (ACO) is a persistent airflow limitation with features of both asthma and chronic obstructive pulmonary disease (COPD). No studies have explored the prevalence of ACO at the national level in China.Objective: In this study, we aimed to estimate the prevalence of ACO and to assess the associated ... Read more >>

Curr Med Res Opin (Current medical research and opinion)
[2020, :1-9]

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Race and Asthma Outcomes in Older Adults: Results from the National Asthma Survey.

Nicole M Cremer, Alan P Baptist,

BACKGROUND:The number of older adults with asthma continues to rise, yet the effects of race and ethnicity on asthma outcomes in this population are unknown. OBJECTIVE:To characterize the effect of race and ethnicity on asthma outcomes in a large national sample of older adults and to identify factors that are ... Read more >>

J Allergy Clin Immunol Pract (The journal of allergy and clinical immunology. In practice)
[2020, :]

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Readmission and Ambulatory Health Care Use After Asthma Hospitalization Among Urban Minority Children.

Kaitlyn S Philips, Daniel E Reiss, Ellen J Silver, Deepa Rastogi,

OBJECTIVES:The role of ambulatory follow-up after pediatric asthma hospitalization in preventing long-term readmissions is not well studied among hospitalized minority children. We sought to examine the association of ambulatory visit attendance with long-term readmission as well as identify predictors of attendance at these visits among urban, minority children with asthma. ... Read more >>

Hosp Pediatr (Hospital pediatrics)
[2020, :]

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Race, Ethnicity, Socioeconomic Status, and Chronic Lung Disease in the U.S.

Shervin Assari, Hamid Chalian, Mohsen Bazargan,

BackgroundHigher socioeconomic status (SES) indicators such as educational attainment and income reduce the risk of chronic lung diseases (CLDs) such as Chronic Obstructive Pulmonary Disease (COPD), emphysema, chronic bronchitis, and asthma. Marginalization-related Diminished Returns (MDRs) refer to smaller health benefits of high SES for marginalized populations such as racial and ... Read more >>

Res Health Sci (Research in health science)
[2020, 5(1):48-63]

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Cetirizine use in childhood: an update of a friendly 30-year drug.

Giuseppe Fabio Parisi, Salvatore Leonardi, Giorgio Ciprandi, Angelo Corsico, Amelia Licari, Michele Miraglia Del Giudice, Diego Peroni, Carmelo Salpietro, Gian Luigi Marseglia,

Cetirizine is a second-generation antihistamine, derived from the metabolism of hydroxyzine, highly specific for the H1 receptors, and with marked antiallergic properties. Although its history began more than 30 years ago, it remains one of the most used drugs in children with a leading role in the medical care of children ... Read more >>

Clin Mol Allergy (Clinical and Molecular Allergy : CMA)
[2020, 18:2]

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Osteopontin contributes to late-onset asthma phenotypes in adult asthma patients.

Hoang Kim Tu Trinh, Thuy Van Thao Nguyen, Seo-Hee Kim, Thi Bich Tra Cao, Quoc Quang Luu, Seung-Hyun Kim, Hae-Sim Park,

Patients with late-onset asthma (LOA) have poor clinical outcomes. Osteopontin (OPN) is associated with airway inflammation and remodeling. To investigate the role of OPN in LOA compared to early-onset asthma (EOA), serum OPN levels were compared between 131 adult asthma patients (48 LOA and 83 EOA patients) and 226 healthy ... Read more >>

Exp. Mol. Med. (Experimental & molecular medicine)
[2020, 52(2):253-265]

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Rare case of vascular ring with Kommerell diverticulum mimicking uncontrolled asthma.

Ahmed Ben Saad, Nesrine Fahem, Houda Ben Saad, Asma Migaou, Chokri Kortas, Samah Joobeur,

Anomalies of the aortic arch associated with Kommerell diverticulum (KD) are rare congenital malformations. Symptomatic thoracic vascular rings presenting in adults are rare. We report a case of a 39-year-old woman who was diagnosed with uncontrolled asthma. She was complaining of worsening respiratory symptoms with dysphagia. Imaging studies and preoperative ... Read more >>

Respirol Case Rep (Respirology case reports)
[2020, 8(3):e00535]

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Recommendations for 24-Hour Movement Behaviours in Adults with Asthma: A Review of Current Guidelines.

Shilpa Dogra, Ilana Patlan, Carley O'Neill, Hayley Lewthwaite,

Background: Many countries have clinical practice guidelines (CPG) for asthma that serve as an important resource for healthcare professionals and inform the development of policies and practices relevant to asthma care. The purpose of this scoping review was to search for CPGs related to asthma to determine what recommendations related ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(5):]

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Development of a fall-risk assessment profile for community-dwelling older adults by using the National Health Interview Survey in Taiwan.

Ping-Ling Chen, Hsiao-Yu Lin, Jiann Ruey Ong, Hon-Ping Ma,

BACKGROUND:Falls represent a global health issue among older adults and cause a considerable burden on medical systems. In this study, a fall-risk assessment profile was developed for community-dwelling older adults. METHOD:The data of survey participants aged > 65 years were obtained from three rounds (2005, 2009, and 2013) of the National Health ... Read more >>

BMC Public Health (BMC public health)
[2020, 20(1):234]

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Association of Sex Steroid Hormones with Adult Asthma in the United States, 2013-2016.

Yuewei Liu, Yun Zhou,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, 201(5):618-619]

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Omalizumab as add-on therapy in a patient with severe asthma and OSA.

Giulia Scioscia, Enrico Buonamico, Maria Pia Foschino Barbaro, Donato Lacedonia, Roberto Sabato, Giovanna Elisiana Carpagnano,

Obstructive sleep apnoea (OSA) syndrome, the most frequent sleep-disordered breathing, is a comorbidity of asthma, whose prevalence covers about 49.5% of asthmatic adult patients. A 61-year-old female patient, affected by severe allergic asthma and obesity, started treatment with omalizumab and underwent polysomnography showing a severe OSA pattern (apnoea/hypopnoea index (AHI): ... Read more >>

Respirol Case Rep (Respirology case reports)
[2020, 8(2):e0518]

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