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Asbestosis

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[Sustainability in Outpatient Pulmonary Rehabilitation in Patients with Asbestosis - Results of an 8-Year Follow Up].

S Dalichau, T Möller,

BACKGROUND: The aim of this study was to evaluate the effects of an outpatient medical rehabilitation (OMR) mainly composed of exercise therapy and sports for patients with asbestosis and focused on keeping up sustainability effects. METHODS: 157 male patients aged 65.2 ± 5.7 years suffering from asbestosis carried out over a period of three ... Read more >>

Pneumologie (Pneumologie (Stuttgart, Germany))
[2020, :]

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Evaluation of soluble mesothelin-related peptides and MSLN genetic variability in asbestos-related diseases.

Katja Goricar, Viljem Kovac, Metoda Dodic-Fikfak, Vita Dolzan, Alenka Franko,

Background Asbestos exposure is associated with increased risk of several diseases, including malignant mesothelioma (MM). Cell surface glycoprotein mesothelin is overexpressed in MM and serum soluble mesothelin-related peptides (SMRP) were already proposed as a diagnostic or prognostic biomarker in MM. However, interindividual variability in serum SMRP levels limits the clinical ... Read more >>

Radiol Oncol (Radiology and oncology)
[2020, 54(1):86-95]

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Trends in global, regional and national incidence of pneumoconiosis caused by different aetiologies: an analysis from the Global Burden of Disease Study 2017.

Peng Shi, Xiaoyue Xing, Shuhua Xi, Hongmei Jing, Jiamei Yuan, Zhushan Fu, Hanqing Zhao,

OBJECTIVES:Pneumoconiosis remains a major global occupational health hazard and illness. Accurate data on the incidence of pneumoconiosis are critical for health resource planning and development of health policy. METHODS:We collected data for the period between 1990 and 2017 on the annual incident cases and the age-standardised incidence rates (ASIR) of ... Read more >>

Occup Environ Med (Occupational and environmental medicine)
[2020, :]

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Malignant Diffuse Mesothelioma in Women: A Study of 354 Cases.

Elizabeth N Pavlisko, Beiyu Liu, Cindy Green, Thomas A Sporn, Victor L Roggli,

We reviewed 354 cases of malignant diffuse mesothelioma (MM) in women from a database of 2858 histologically confirmed MM cases. There was a pleural predominance with 78% pleural MM and 22% peritoneal MM. The pleural tumors consisted of 72% epithelioid, 19% biphasic, and 9% sarcomatoid variant. The peritoneal tumors consisted ... Read more >>

Am. J. Surg. Pathol. (The American journal of surgical pathology)
[2020, 44(3):293-304]

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Asbestos, Smoking and Lung Cancer: An Update.

Sonja Klebe, James Leigh, Douglas W Henderson, Markku Nurminen,

This review updates the scientific literature concerning asbestos and lung cancer, emphasizing cumulative exposure and synergism between asbestos exposure and tobacco smoke, and proposes an evidence-based and equitable approach to compensation for asbestos-related lung cancer cases. This update is based on several earlier reviews written by the second and third ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2019, 17(1):]

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[Diagnostic Challenges of Mixed Dust Silicosis (Mixed Dust Pneumoconiosis) - 5 Case Reports].

X Baur,

Exposure to granular or fibrous inorganic dusts of the alveolar dust fraction initiates inflammatory and fibrotic lung processes. Furthermore, such exposures are associated with an increased risk for lung cancer. By taking a detailed occupational history into consideration the diagnosis of relatively frequent pneumoconioses such as silicosis or asbestosis with ... Read more >>

Pneumologie (Pneumologie (Stuttgart, Germany))
[2020, 74(3):159-172]

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Pleural Plaques and the Risk of Lung Cancer in Asbestos-exposed Subjects.

Fraser J H Brims, Karen Kong, Ed J A Harris, Nita Sodhi-Berry, Alison Reid, Conor P Murray, Peter J Franklin, A Bill Musk, Nicholas H de Klerk,

Rationale: Asbestos exposure is associated with a dose-dependent risk of lung cancer. The association between lung cancer and the presence of pleural plaques remains controversial.Objectives: To define the relationship between pleural plaques and lung cancer risk.Methods: Subjects were from two cohorts: 1) crocidolite mine and mill workers and Wittenoom Township ... Read more >>

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, 201(1):57-62]

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[Diffuse Intraparenchymal Mesothelioma: An Atypical Presentation].

Ana Pais, Nicole Pinto, João Cardoso, Manuel Fernandes, Ana Isabel Coutinho, Ana Sofia Oliveira, Lurdes Carvalho, Cristina Bárbara,

Pleural mesothelioma is a disease associated with exposure to asbestos. Although rare, it is the most common malignant pleural neoplasm. It is difficult to diagnose and it has a poor prognosis. We report the case of a 62-year-old male patient with a history of prolonged occupational exposure to asbestos, with ... Read more >>

Acta Med Port (Acta medica portuguesa)
[2020, 33(2):143-146]

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Asbestos, Pleural Plaques, and Lung Cancer: Untangling the Relationships.

Philip Harber,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, 201(1):4-6]

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Position Paper on Asbestos of the Italian Society of Occupational Medicine.

Pietro Apostoli, Paolo Boffetta, Massimo Bovenzi, Pier Luigi Cocco, Dario Consonni, Alfonso Cristaudo, Gianluigi Discalzi, Andrea Farioli, Maurizio Manno, Stefano Mattioli, Enrico Pira, Leonardo Soleo, Giuseppe Taino, Francesco Saverio Violante, Carlo Zocchetti,

The Position Paper (PP) on asbestos of the Italian Society of Occupational Medicine (SIML) aims at providing a tool to the occupational physician to address current diagnostic criteria and results of epidemiological studies, and their consequences in terms of preventive and evaluation actions for insurance, compensation and litigation. The PP ... Read more >>

Med Lav (La Medicina del lavoro)
[2019, 110(6):459-485]

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The MUC5B promoter risk allele for idiopathic pulmonary fibrosis predisposes to asbestosis.

Mark G J P Platenburg, Ivo A Wiertz, Joanne J van der Vis, Bruno Crestani, Raphael Borie, Philippe Dieude, Caroline Kannengiesser, Jacobus A Burgers, Jan C Grutters, Coline H M van Moorsel,

Eur. Respir. J. (The European respiratory journal)
[2020, :]

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Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study.

Theodore C Larson, Laura Williamson, Vinicius C Antao,

OBJECTIVE:To evaluate mortality patterns among participants in a community-based screening program for asbestos-related disease. METHODS:We calculated standardized mortality ratios (SMRs) and stratified results by exposure group (three occupational exposure groups, household contacts and residents without occupational asbestos exposure) and by radiographic abnormality presence. RESULTS:All-cause mortality (15.8%; 1,429/8,043) was statistically lower ... Read more >>

J. Occup. Environ. Med. (Journal of occupational and environmental medicine)
[2020, 62(1):e1-e6]

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Mortality and mesothelioma incidence among chrysotile asbestos miners in Balangero, Italy: A cohort study.

Daniela Ferrante, Dario Mirabelli, Stefano Silvestri, Danila Azzolina, Andrea Giovannini, Patrizia Tribaudino, Corrado Magnani,

BACKGROUND:We studied cancer mortality and mesothelioma incidence in 974 male workers employed at least 6 months at the Balangero mine (Italy), the largest chrysotile mine in Western Europe, active from 1917 to 1985. METHODS:Vital status as of 31 May 2013, causes of deaths and mesothelioma incidence from 1990 were ascertained. ... Read more >>

Am. J. Ind. Med. (American journal of industrial medicine)
[2020, 63(2):135-145]

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The trends in global, regional, and national incidence of pneumoconiosis caused by different etiologies: an analysis from the Global Burden of Disease Study 2017

Shuhua Xi, Peng Shi, Xiaoyue Xing, Hongmei Jing, Jiamei Yuan, Zhushan Fu, Hanqing Zhao,

<title>Abstract</title> <p> Pneumoconiosis has the potential to cause progressive and permanent physical disability. And continues to be one of major public health concern across the world. However, our literature searches identified a scarcity of data about global prevalence of pneumoconiosis. Accurate data on the incidence of pneumoconiosis is ... Read more >>

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[The occurrence of asbestos-related diseases among former employees of asbestos processing plants in Poland].

Beata Świątkowska,

BACKGROUND:Despite the fact that asbestos is no longer used in production in Poland, there are still new cases of asbestos-related diseases among workers previously exposed to asbestos dust. This situation is related to the specificity of the biological activity of this mineral; the health consequences of asbestos can manifest not ... Read more >>

Med Pr (Medycyna pracy)
[2019, 70(6):723-731]

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Asbestosis and silicosis hospitalizations in Italy (2001-2015): results from the National Hospital Discharge Registry.

Pierpaolo Ferrante,

BACKGROUND:This work is aimed at evaluating the quality of Italian hospitalizations data about asbestosis and silicosis, assessing the impact of these diseases on the national health system and providing advice related to public health. METHODS:Italian hospital discharge data (2001-15) with diagnosis of asbestosis or silicosis were analysed by the multiple ... Read more >>

Eur J Public Health (European journal of public health)
[2019, 29(5):876-882]

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Relationship between pleural plaques and biomarkers of cumulative asbestos dose. A necropsy study.

Pietro Gino Barbieri, Dario Consonni, Anna Somigliana,

BACKGROUND:The relationship between pleural plaques and cumulative asbestos exposure is controversial. OBJECTIVES:To evaluate the relationship between lung asbestos bodies (AB) and fibres (AF) and plaques presence and extension. METHODS:In a necropsy series of shipyard workers with asbestos-related diseases, we measured counts (per g of dry lung tissue) of AB (thousands) ... Read more >>

Med Lav (La Medicina del lavoro)
[2019, 110(5):353-362]

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[Incidence and yrend of occupational pneumoconiosis in Ankang city from 1974 to 2017].

X Y Yang, G Y Liu, H M Wang,

Objective: To understand the epidemiological feature and prevalent trend of pneumoconiosis in Ankang City, pertinently put forward the prevention and control strategy, and provide the basis for comprehensive prevention and treatment of pneumoconiosis. Methods: China Information System for Disease Control and Prevention has exported the network report data of "occupational ... Read more >>

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi (Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases)
[2019, 37(12):918-920]

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SURVEILLANCE PROGRAM IDENTIFIES HEALTH OUTCOMES FOR FORMER WORKERS.

Ashley Golden, Jeffery Miller, Zachariah Hubbell, Sara Howard, Donna Cragle,

AbstractAccording to the US Bureau of Labor Statistics, the average age of retirement is 62. While many retirees may have employer-provided or other access to healthcare, others have limited access to affordable care until full Medicare eligibility at 65. Regardless of access, retirees with toxic occupational exposures may not have ... Read more >>

Innov Aging (Innovation in aging)
[2019, 3(Suppl 1):S950-S950]

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Pleural plaques: only an imagiologic finding?

Paulo Almeida, Ana Araújo,

Pan Afr Med J (The Pan African medical journal)
[2019, 34:156]

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Occurrence, behaviour, and human exposure pathways and health risks of toxic geogenic contaminants in serpentinitic ultramafic geological environments (SUGEs): A medical geology perspective.

Willis Gwenzi,

Serpentinitic ultramafic geological environments (SUGEs) contain toxic geogenic contaminants (TGCs). Yet comprehensive reviews on the medical geology of SUGEs are still lacking. The current paper posits that TGCs occur widely in SUGEs, and pose human health risks. The objectives of the review are to: (1) highlight the nature, occurrence and ... Read more >>

Sci. Total Environ. (The Science of the total environment)
[2020, 700:134622]

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The Wittenoom legacy.

Arthur W Bill Musk, Alison Reid, Nola Olsen, Michael Hobbs, Bruce Armstrong, Peter Franklin, Jennie Hui, Lenore Layman, Enzo Merler, Fraser Brims, Helman Alfonso, Keith Shilkin, Nita Sodhi-Berry, Nicholas de Klerk,

The Wittenoom crocidolite (blue asbestos) mine and mill ceased operating in 1966. The impact of this industry on asbestos-related disease in Western Australia has been immense. Use of the employment records of the Australian Blue Asbestos Company and records of the Wittenoom township residents has permitted two cohorts of people ... Read more >>

Int J Epidemiol (International journal of epidemiology)
[2019, :]

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A case of hypersensitivity pneumonitis in a worker exposed to terephthalic acid in the production of polyethylene terephthalate.

Pietro Sartorelli, Gabriele d'Hauw, Donatella Spina, Luca Volterrani, Maria Antonietta Mazzei,

Occupational hypersensitivity pneumonitis (OHP) is an interstitial lung disease caused by sensitization to an inhaled antigen. Polyethylene terephthalate (PET) is mainly used for disposable beverage bottles. A clinical case of hypersensitivity pneumonitis (HP) in a 66-year-old patient in the follow-up as a worker formerly exposed to asbestos is presented. At ... Read more >>

Int J Occup Med Environ Health (International journal of occupational medicine and environmental health)
[2020, 33(1):119-123]

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Current Asbestos Exposure and Future Need for Palliative Care in India.

Abhijeet Vasant Jadhav, Nilesh C Gawde,

Asbestos-related diseases (ARDs) are incurable but entirely preventable. Due to India's continuing use of asbestos, ARD patients will increase to a high number in the next three to four decades. This will increase the burden on palliative care system which is in nascent stage presently. Palliative care is the mainstay ... Read more >>

Indian J Palliat Care (Indian journal of palliative care)
[2019, 25(4):587-591]

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NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis.

Chao He, Jennifer L Larson-Casey, Dana Davis, Vidya Sagar Hanumanthu, Ana Leda F Longhini, Victor J Thannickal, Linlin Gu, A Brent Carter,

Macrophage activation is implicated in the development of pulmonary fibrosis by generation of profibrotic molecules. Although NADPH oxidase 4 (NOX4) is known to contribute to pulmonary fibrosis, its effects on macrophage activation and mitochondrial redox signaling are unclear. Here, we show that NOX4 is crucial for lung macrophage profibrotic polarization ... Read more >>

JCI Insight (JCI insight)
[2019, 4(16):]

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