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Apraxia of Lid Opening

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Myotomy In Situ for Essential Blepharospasm Refractory to Botulinum Toxin.

Hsin-Ti Lai, Austin D Chen, Su-Shin Lee, Yi-Hui Lin, Chung-Sheng Lai,

BACKGROUND:Full myectomy is recommended for benign essential blepharospasm (BEB) refractory to botulinum toxin (BT) treatment, but long-term swelling, scar contracture, hollow appearance, and unnatural contour of the eyelids are common postoperative complications. We present myotomy in situ to minimize these adverse outcomes. METHODS:The redundant eyelid skin with its underlying muscle ... Read more >>

Ann Plast Surg (Annals of plastic surgery)
[2020, 84(1S Suppl 1):S74-S79]

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Mini-incisional entropion repair for correcting involutional entropion: Full description and surgical outcome.

Jisang Han, Shin-Hyo Lee, Hyun Jin Shin,

The aim of the study was to report the surgical outcome of mini-incisional correction method to treat involutional entropion.This is a retrospective interventional case series of 46 eyelids in 31 patients with involutional entropion and significant ocular irritation. In this technique, after turning the lower eyelid inside out, threads are ... Read more >>

Medicine (Baltimore) (Medicine)
[2019, 98(33):e16731]

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"Feasibility and utility of a simple computerized test for measuring saccade latency in progressive supranuclear palsy- a proof-of-concept study".

Marian L Dale, Emmi P Scott, Saher Khalid, Andrew S Eiseman, Travis H Turner,

Background:Reliable detection of slowed vertical saccades may help discriminate progressive supranuclear palsy (PSP) from the subset of Parkinson's disease patients who lack tremor (akinetic-rigid or PD-postural instability and gait disorder PIGD subtype), and from age-related oculomotor changes. We investigated the feasibility of a camera-less computerized behavioral saccade latency paradigm previously ... Read more >>

J Clin Mov Disord (Journal of clinical movement disorders)
[2019, 6:6]

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Abnormal Eye Movements in Parkinsonism and Movement Disorders.

Ileok Jung, Ji-Soo Kim,

Abnormal eye movements are commonly observed in movement disorders. Ocular motility examination should include bedside evaluation and laboratory recording of ocular misalignment, involuntary eye movements, including nystagmus and saccadic intrusions/oscillations, triggered nystagmus, saccades, smooth pursuit (SP), and the vestibulo-ocular reflex. Patients with Parkinson's disease (PD) mostly show hypometric saccades, especially ... Read more >>

J Mov Disord (Journal of movement disorders)
[2019, 12(1):1-13]

Cited: 1 time

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Awakening Ptosis: A Clinical Review.

Abidemi Idowu Otaiku,

A rare condition characterized by a transient inability to open one or both eyes upon awakening from sleep was first described in 1897. Although less than a handful of papers have been written about this condition since its initial description, a well-defined clinical entity emerges from the available literature. This ... Read more >>

Neuroophthalmology (Neuro-ophthalmology (Aeolus Press))
[2019, 43(1):26-31]

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An augmented reality approach for ADL support in Alzheimer's disease: a crossover trial.

Nina Rohrbach, Philipp Gulde, Alan Robert Armstrong, Linda Hartig, Anas Abdelrazeq, Stefan Schröder, Johanne Neuse, Timo Grimmer, Janine Diehl-Schmid, Joachim Hermsdörfer,

BACKGROUND:Dementia of the Alzheimer's type can impair the performance of activities of daily living and therefore severely impact independent living. Assistive technologies can support such patients when carrying out daily tasks. METHODS:In this crossover study, we used an augmented reality approach using a Microsoft HoloLens to support patients in a ... Read more >>

J Neuroeng Rehabil (Journal of neuroengineering and rehabilitation)
[2019, 16(1):66]

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Oxybuprocaine for apraxia of lid opening in Parkinson's disease: A placebo-controlled pilot trial.

Masayuki Kohsaka, Tomoko Oeda, Atsushi Umemura, Satoshi Tomita, Kwiyoung Park, Kenji Yamamoto, Hiroshi Sugiyama, Hideyuki Sawada,

Mov. Disord. (Movement disorders : official journal of the Movement Disorder Society)
[2018, 33(3):494-495]

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Botulinum toxin for treating unilateral apraxia of eyelid opening in a patient with congenital myotonia.

Estrella Fernández, Marta Latasiewicz, Laura Pelegrin, Manuel Romera, Silvana Schellini, Alicia Galindo-Ferreiro,

A 37-year-old female presented with severe apraxia of lid opening (ALO) affecting the right upper lid associated with Becker congenital myotonia (MC). The patient had a history of right upper lid ptosis for 25 years that was exacerbated over the previous month with severe incapacity to open her right eye. ... Read more >>

Arq Bras Oftalmol (Arquivos brasileiros de oftalmologia)
[2017, 80(5):330-331]

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Characteristics of care methods for daily life disabilities in Alzheimer's type dementia that respect autonomy and independence.

Sayuri Suwa, Akiyo Yumoto, Mari Ueno, Tomoko Yamabe, Yumiko Hoshishiba, Mihoko Sato,

Aim:To clarify the characteristics of appropriate care methods for people with daily life disabilities due to Alzheimer's type dementia. Design:A cross-sectional survey study. Methods:A survey was implemented targeting 2,156 advanced care practitioners for dementia. The postal, self-administered anonymous questionnaire was rated on a 4-point Likert scale to assess the benefits ... Read more >>

Nurs Open (Nursing open)
[2019, 6(3):930-941]

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Eyelid Dysfunction in Neurodegenerative, Neurogenetic, and Neurometabolic Disease.

Ali G Hamedani, Daniel R Gold,

Eye movement abnormalities are among the earliest clinical manifestations of inherited and acquired neurodegenerative diseases and play an integral role in their diagnosis. Eyelid movement is neuroanatomically linked to eye movement, and thus eyelid dysfunction can also be a distinguishing feature of neurodegenerative disease and complements eye movement abnormalities in ... Read more >>

Front Neurol (Frontiers in neurology)
[2017, 8:329]

Cited: 2 times

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123I-FP-CIT SPECT imaging in blepharospasm.

M De Verdal, D Renard, L Collombier, G Castelnovo,

Blepharospasm is a focal dystonia characterized by involuntary cocontraction of the eyelid protractors, causing spasmodic closure of the eyelids. Apraxia of eyelid opening is caused by an inability to initiate lid opening without paralytic abnormality. Some studies suggest that patients with either pure blepharospasm or blepharospasm associated with apraxia of ... Read more >>

Rev. Neurol. (Paris) (Revue neurologique)
[2017, 173(10):645-649]

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Frontalis suspension surgery to treat patients with blepharospasm and eyelid opening apraxia: long-term results.

Dirk Dressler, Chrisanthi Karapantzou, Saskia Rohrbach, Simon Schneider, Rainer Laskawi,

Blepharospasm may be accompanied by eyelid opening apraxia (EOA) reducing the efficacy of botulinum toxin (BT) therapy. The frontalis suspension operation (FSO) is then the only effective treatment option available. We want to report the first long-term results with FSO. We studied 15 patients with blepharospasm and EAO unresponsive to ... Read more >>

J Neural Transm (Vienna) (Journal of neural transmission (Vienna, Austria : 1996))
[2017, 124(2):253-257]

Cited: 3 times

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Successful treatment of anti-NMDA receptor encephalitis with early teratoma removal and plasmapheresis: A case report.

Monica Gomes Ferreira, Victoria Lapresa Alcalde, María Helena García Sánchez, Lourdes Hernández Hernández, María José Doyague Sánchez,

This report describes a Successful treatment of anti-NMDA receptor encephalitis with early teratoma removal and plasmapheresis.We present a 31-year-old Caucasian nulliparous patient who was admitted as an emergency with general illness status accompanied by holocranial cephalalgia and fever.The previous symptoms were followed by disorientation, persecutory delusion, incoherent language, and tonic-clonic ... Read more >>

Medicine (Baltimore) (Medicine)
[2018, 97(31):e11325]

Cited: 2 times

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Blepharospasm 40 years later.

Giovanni Defazio, Mark Hallett, Hyder A Jinnah, Antonella Conte, Alfredo Berardelli,

Forty years ago, C.D. Marsden proposed that blepharospasm should be considered a form of adult-onset focal dystonia. In the present paper, we provide a comprehensive overview of the findings regarding blepharospasm reported in the past 40 years. Although prolonged spasms of the orbicularis oculi muscles remain the clinical hallmark of ... Read more >>

Mov. Disord. (Movement disorders : official journal of the Movement Disorder Society)
[2017, 32(4):498-509]

Cited: 10 times

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Are visual functions diagnostic signs of the minimally conscious state? an integrative review.

Berno U H Overbeek, Henk J Eilander, Jan C M Lavrijsen, Raymond T C M Koopmans,

Visual pursuit (VP) and visual fixation (VF) have been recognized as the first signs of emerging consciousness and, therefore, are considered indicative of the minimally conscious state (MCS). However, debate exists about their status as they are considered either conscious reactions or reflexes. The aim of this study is to ... Read more >>

J. Neurol. (Journal of neurology)
[2018, 265(9):1957-1975]

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Familial atypical parkinsonism with rare variant in VPS35 and FBXO7 genes: A case report.

Tereza Bartonikova, Katerina Mensikova, Lenka Mikulicova, Radek Vodicka, Radek Vrtel, Marek Godava, Miroslav Vastik, Michaela Kaiserova, Pavel Otruba, Iva Dolinova, Martin Nevrly, Petr Kanovsky,

A higher prevalence of parkinsonism was recently identified in southeastern Moravia (Czech Republic). Further research confirmed 3 large pedigrees with familial autosomal-dominant parkinsonism spanning 5 generations.This case report concerns a patient belonging to one of these 3 pedigrees, in whom motor and oculomotor symptoms were accompanied by frontal-type dementia, who ... Read more >>

Medicine (Baltimore) (Medicine)
[2016, 95(46):e5398]

Cited: 3 times

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Movement disorders with neuronal antibodies: syndromic approach, genetic parallels and pathophysiology.

Bettina Balint, Angela Vincent, Hans-Michael Meinck, Sarosh R Irani, Kailash P Bhatia,

Movement disorders are a prominent and common feature in many autoantibody-associated neurological diseases, a group of potentially treatable conditions that can mimic infectious, metabolic or neurodegenerative disease. Certain movement disorders are likely to associate with certain autoantibodies; for example, the characteristic dyskinesias, chorea and dystonia associated with NMDAR antibodies, stiff ... Read more >>

Brain (Brain : a journal of neurology)
[2018, 141(1):13-36]

Cited: 14 times

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Blepharospasm: Update on Epidemiology, Clinical Aspects, and Pathophysiology.

Josep Valls-Sole, Giovanni Defazio,

Blepharospasm (BSP) is a rather distressing form of focal dystonia. Although many aspects of its pathophysiological mechanisms are already known, we lack fundamental evidence on etiology, prevention, and treatment. To advance in our knowledge, we need to review what is already known in various aspects of the disorder and use ... Read more >>

Front Neurol (Frontiers in neurology)
[2016, 7:45]

Cited: 13 times

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Frontalis suspension surgery to treat patients with essential blepharospasm and apraxia of eyelid opening-technique and results.

Chrisanthi Karapantzou, Dirk Dressler, Saskia Rohrbach, Rainer Laskawi,

INTRODUCTION: We describe the results of 15 patients suffering from essential blepharospasm with apraxia of eyelid opening who underwent frontalis suspension surgery. MATERIAL AND METHODS: Patients with apraxia of eyelid opening and unresponsive to botulinum toxin injections were studied. Bilateral frontalis suspension surgery was performed (sling operation) using polytetrafluoroethylene (Gore-Tex®) ... Read more >>

Head Face Med (Head & face medicine)
[2014, 10:44]

Cited: 4 times

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A Dynamic Circuit Hypothesis for the Pathogenesis of Blepharospasm.

David A Peterson, Terrence J Sejnowski,

Blepharospasm (sometimes called "benign essential blepharospasm," BEB) is one of the most common focal dystonias. It involves involuntary eyelid spasms, eye closure, and increased blinking. Despite the success of botulinum toxin injections and, in some cases, pharmacologic or surgical interventions, BEB treatments are not completely efficacious and only symptomatic. We ... Read more >>

Front Comput Neurosci (Frontiers in computational neuroscience)
[2017, 11:11]

Cited: 3 times

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PLA2G6-associated Dystonia-Parkinsonism: Case Report and Literature Review.

Siamak Karkheiran, Gholam Ali Shahidi, Ruth H Walker, Coro Paisán-Ruiz,

Phospholipase-associated neurodegeneration (PLAN) caused by PLA2G6 mutations is a recessively inherited disorder with three known phenotypes: the typical infantile onset neuroaxonal dystrophy (INAD); an atypical later onset form (atypical NAD); and the more recently recognized young-onset dystonia-parkinsonism (PLAN-DP).We report the clinical, radiological, and genetic findings of a young Pakistani male ... Read more >>

Tremor Other Hyperkinet Mov (N Y) (Tremor and other hyperkinetic movements (New York, N.Y.))
[2015, 5:317]

Cited: 8 times

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Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria.

Günter U Höglinger, Gesine Respondek, Maria Stamelou, Carolin Kurz, Keith A Josephs, Anthony E Lang, Brit Mollenhauer, Ulrich Müller, Christer Nilsson, Jennifer L Whitwell, Thomas Arzberger, Elisabet Englund, Ellen Gelpi, Armin Giese, David J Irwin, Wassilios G Meissner, Alexander Pantelyat, Alex Rajput, John C van Swieten, Claire Troakes, Angelo Antonini, Kailash P Bhatia, Yvette Bordelon, Yaroslau Compta, Jean-Christophe Corvol, Carlo Colosimo, Dennis W Dickson, Richard Dodel, Leslie Ferguson, Murray Grossman, Jan Kassubek, Florian Krismer, Johannes Levin, Stefan Lorenzl, Huw R Morris, Peter Nestor, Wolfgang H Oertel, Werner Poewe, Gil Rabinovici, James B Rowe, Gerard D Schellenberg, Klaus Seppi, Thilo van Eimeren, Gregor K Wenning, Adam L Boxer, Lawrence I Golbe, Irene Litvan, ,

BACKGROUND:PSP is a neuropathologically defined disease entity. Clinical diagnostic criteria, published in 1996 by the National Institute of Neurological Disorders and Stroke/Society for PSP, have excellent specificity, but their sensitivity is limited for variant PSP syndromes with presentations other than Richardson's syndrome. OBJECTIVE:We aimed to provide an evidence- and consensus-based ... Read more >>

Mov. Disord. (Movement disorders : official journal of the Movement Disorder Society)
[2017, 32(6):853-864]

Cited: 146 times

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Bilateral ptosis: Lesion in the oculomotor nuclei or supranuclear lesion?

Julien Dimitriou, Timothy Montoute, Marc Levivier, François-Xavier Borruat, Karin Diserens,

Bilateral ptosis is a very interesting clinical challenge for doctors because of the multiple possible localizations of a lesion which can lead to this neurological sign.Through this case report, we aim to determine the difference between an apraxia of lid opening (ALO) with difficulty in initiating the act of lid ... Read more >>

NeuroRehabilitation (NeuroRehabilitation)
[2015, 36(3):323-327]

Cited: 1 time

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Comparison of Two Botulinum Neurotoxin A Injection Patterns with or without the Medial Lower Eyelid in the Treatment of Blepharospasm.

Hui Yang, Jing Lu, Xiujuan Zhao, Xiaohu Ding, Zhonghao Wang, Xiaoyu Cai, Yan Luo, Lin Lu,

The aim of this study was to evaluate the efficacy of two botulinum toxin A (BoNT-A) injection patterns with or without the medial lower eyelid (MLE) in treating benign essential blepharospasm (BEB) and influencing lacrimal drainage. Two different injection patterns of BoNT-A were randomly applied to 98 eyes of 49 ... Read more >>

J Ophthalmol (Journal of ophthalmology)
[2016, 2016:5957812]

Cited: 2 times

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An autopsy-confirmed case of progressive supranuclear palsy with predominant postural instability.

Carolin Kurz, Georg Ebersbach, Gesine Respondek, Armin Giese, Thomas Arzberger, Günter Ulrich Höglinger,

Postural instability and supranuclear gaze palsy represent the key symptoms of Richardson's syndrome, the most frequent clinical manifestation of progressive supranuclear palsy (PSP). However, a proportion of PSP patients never develops ocular motor symptoms, which prevents clinicians from establishing the diagnosis during lifetime according to current diagnostic criteria. We present ... Read more >>

Acta Neuropathol Commun (Acta neuropathologica communications)
[2016, 4(1):120]

Cited: 4 times

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