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Prenatal genetic diagnosis of omphalocele by karyotyping, chromosomal microarray analysis and exome sequencing.

Xiaomei Shi, Hui Tang, Jian Lu, Xiue Yang, Hongke Ding, Jing Wu,

<h4>Objectives</h4>The aim of this study is to share our experience in the prenatal diagnosis of omphalocele by karyotyping, chromosomal microarray analysis (CMA) and whole exome sequencing (WES).<h4>Methods</h4>In this retrospective study, 81 cases of omphalocele were identified from 2015 to 2020. Associated anomalies and prenatal diagnosis based on karyotyping, CMA and ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1285-1291]

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Understanding empowerment for a healthy dietary intake during pregnancy.

Sabina Super, Annemarie Wagemakers,

<b>Purpose</b>: In order for health professionals to encourage pregnant women with a low socioeconomic status (SES) to move towards empowerment for a healthy dietary intake, crucial steps are to understand the perspectives of pregnant women of food and eating and to identify opportunities for empowerment. This study aimed to examine ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2021, 16(1):1857550]

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Four specific biomarkers associated with the progression of glioblastoma multiforme in older adults identified using weighted gene co-expression network analysis.

Yushi Yang, Liangzhao Chu, Zhirui Zeng, Shu Xu, Hua Yang, Xuelin Zhang, Jun Jia, Niya Long, Yaxin Hu, Jian Liu,

Glioblastoma multiforme (GBM) is the most common primary intracranial malignancy in adults. Owing to individual tolerance and tumor heterogeneity, the therapy methods for young adults do not apply to older adults. The present study aimed to identify specific biomarkers for GBM in older adults using weighted gene co-expression network analysis ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):6643-6654]

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"When I think of mental healthcare, I think of no care." Mental Health Services as a Vital Component of Prenatal Care for Black Women.

Shakkaura Kemet, Yihui Yang, Onouwem Nseyo, Felicha Bell, Anastasia Yinpa-Ala Gordon, Markita Mays, Melinda Fowler, Andrea Jackson,

<h4>Purpose</h4>Black people give birth joyously despite disproportionate rates of adverse perinatal outcomes. Given that group prenatal care shows promise in mitigating these inequities, we sought to solicit the opinions of Black peripartum women on how group prenatal care could be tailored to fit their specific needs. In this study, we ... Read more >>

Matern Child Health J (Maternal and child health journal)
[2021, :]

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Direct PCR assays without DNA extraction for rapid detection of hemoglobin Constant Spring and Pakse' genes: application for carrier screening and prenatal diagnosis.

Phongsathorn Wichian, Supawadee Yamsri, Attawut Chaibunruang, Cholthicha KerdKaew, Dhanawan Thongsee, Hataichanok Srivorakun, Supan Fucharoen,

Hemoglobin Constant Spring (Hb CS) and Hb Pakse' (PS) are the common non-deletional α<sup>+</sup>-thalassemia found in Thailand. These two variants can cause severe thalassemia syndromes, especially in fetus and neonate. Molecular diagnosis is the only confirmatory method because Hb CS and Hb PS are usually missed by routine screening and ... Read more >>

Scand J Clin Lab Invest (Scandinavian journal of clinical and laboratory investigation)
[2021, :1-7]

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Changes in the birth prevalence of orofacial clefts in Japan: Has the birth prevalence of orofacial clefts been affected by improved accuracy of prenatal diagnosis?

Nagato Natsume, Hiroo Furukawa, Teruyuki Niimi, Kazuo Takeuchi, Waka Yoshida, Chisato Sakuma, Hideto Imura, Kumiko Fujiwara, Junko Akashi, Kayo Hayami, Nagana Natsume,

We have been conducting a survey on the birth prevalence of orofacial clefts, including cleft lip with or without cleft palate and cleft palate, in the Tokai area in central Japan every year for 37 years. Along with the yearly trends in the birth prevalence of orofacial clefts in that area ... Read more >>

Congenit Anom (Kyoto) (Congenital anomalies)
[2021, :]

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Antenatal care dropout and associated factors among mothers delivering in public health facilities of Dire Dawa Town, Eastern Ethiopia.

Dereje Worku, Daniel Teshome, Chalachew Tiruneh, Alemtsehay Teshome, Gete Berihun, Leykun Berhanu, Zebader Walle,

<h4>Introduction</h4>More than two-thirds of the pregnant women in Africa have at least one antenatal care contact with a health care provider. However, to achieve the full life-saving potential that antenatal care promises for women and babies, four visits providing essential evidence-based interventions - a package often called focused antenatal care ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2021, 21(1):623]

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Interventions to treat fear of childbirth in pregnancy: a systematic review and meta-analysis

Rebecca Webb, Rod Bond, Borja Romero-Gonzalez, Rachel Mycroft, Susan Ayers,

<h4>Background</h4> Between 5% and 14% of women suffer from fear of childbirth (FOC) which is associated with difficulties during birth and in postnatal psychological adjustment. Therefore, effective interventions are needed to improve outcomes for women. A systematic review and meta-analysis was used to identify effective interventions for treating women with ... Read more >>

Psychol Med (Psychological medicine)
[0, 51(12):1964-1977]

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Prenatal diagnosis in Nevada for patients undergoing cardiovascular surgery in the first six months.

William N Evans, Ruben J Acherman, Michael L Ciccolo, Juan Lehoux, Humberto Restrepo,

<h4>Objective</h4>We reviewed our center's experience with prenatal detection in Nevada's general population for young infants undergoing cardiovascular surgery.<h4>Methods</h4>We identified patients born in Nevada that underwent an initial cardiovascular surgery between 0 and 6 months old with birth dates between August 2012 and July 2021. Additionally, we calculated prenatal congenital cardiovascular ... Read more >>

J Card Surg (Journal of cardiac surgery)
[2021, :]

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Prenatal Diagnosis Leads to Early Diagnosis of Transfusion-Dependent Thalassemia and Better Growth Outcomes.

Natthida Asawasudsakorn, Supanun Lauhasurayotin, Hansamon Poparn, Kanhatai Chiengthong, Darintr Sosothikul, Noppadol Chaiyasit, Piti Techavichit,

Thalassemia is the most common hematological transfusion-dependent disease in Thailand. Even though prenatal diagnosis (PND) can detect the condition, many new cases are diagnosed in pediatric practice. This study assessed the clinical outcome of patients with thalassemia who did PND. One hundred and six participants (53 female, 50%), with a ... Read more >>

Glob Pediatr Health (Global pediatric health)
[2021, 8:2333794X211046104]

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STIC-HD live flow in antenatal diagnosis of double vascular rings: case of right aortic arch with aberrant left subclavian artery and concurrent complete pulmonary artery sling.

L Chen, L Zhou, Y Guo, C Liu, J Xi,

Ultrasound Obstet Gynecol (Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology)
[2021, :]

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Prenatal diagnosis of thalassemia in 695 pedigrees from southeastern China: a 10-year follow-up study.

Hailong Huang, Meihuan Chen, Lingji Chen, Min Zhang, Yan Wang, Na Lin, Liangpu Xu,

Thalassaemia is highly prevalent in southeastern China. This 10-year follow-up study aimed to characterize the genotype and karyotype of thalassaemia in fetal samples derived from thalassemia carriers in Fujian province, southeastern China. A total of 476 prenatal samples from 472 couples carrying α-thalassaemia traits and 224 samples from 223 couples carrying ... Read more >>

J Clin Lab Anal (Journal of clinical laboratory analysis)
[2021, :e23982]

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Prenatal diagnosis and planned peripartum care improve perinatal outcome of fetuses with transposition of the great arteries and intact ventricular septum in low-resource settings.

F Kunde, S Thomas, A Sudhakar, R Kunjikutty, R K Kumar, B Vaidyanathan,

<h4>Objective</h4>To report on the feasibility of establishing a regional prenatal referral network for critical congenital heart defects (CHDs) and its impact on perinatal outcome of fetuses with transposition of the great arteries and intact ventricular septum (TGA-IVS) in low-resource settings.<h4>Methods</h4>This was a retrospective study of consecutive fetuses with a diagnosis ... Read more >>

Ultrasound Obstet Gynecol (Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology)
[2021, 58(3):398-404]

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Microcephaly primary hereditary (MCPH): Report of novel ASPM variants and prenatal diagnosis in a Vietnamese family.

Thinh Huy Tran, Quang Minh Diep, My Ha Cao, Long Hoang Luong, Van Anh Pham, Oanh Thi Lan Dinh, The-Hung Bui, Thanh Van Ta, Van Khanh Tran,

<h4>Objective</h4>MCPH (microcephaly primary hereditary) is a group of autosomal recessive developmental disorders with microcephaly present at birth and intellectual disability. Since a second trimester ultrasound is not able to detect subtypes with minimal prenatal presentations, only prenatal diagnosis by genetic testing can confirm these cases and allow for effective genetic ... Read more >>

Taiwan J Obstet Gynecol (Taiwanese journal of obstetrics & gynecology)
[2021, 60(5):907-910]

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Antenatal care policy in high-income countries with a universal health system: a scoping review

Andreia Soares Goncalves, Isabel Maria Ferreira, Márcia Pestana-Santos, Christine McCourt, Ana Paula Prata,

The availability, effectiveness, and access to antenatal care are directly linked with good maternal and neonatal outcomes, making antenatal care an important determinant in health. But to be effective, care must always be appropriate, not excessive, not insufficient. Perinatal outcomes vary within and between countries, raising questions about practices, the ... Read more >>

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A systematic review of providers' experiences of facilitating group antenatal care.

Jalana Lazar, Laura Boned-Rico, Ellinor K Olander, Christine McCourt,

<h4>Background</h4>Group antenatal care is a rapidly expanding alternative antenatal care delivery model. Research has shown it to be a safe and effective care model for women, but less is known about the perspectives of the providers leading this care. This systematic review examined published literature that considered health care professionals' ... Read more >>

Reprod Health (Reproductive health)
[2021, 18(1):180]

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Truncus arteriosus with absent semilunar valve: Prenatal diagnosis and morphology.

Lihong Pu, Jiao Chen,

Prenat Diagn (Prenatal diagnosis)
[2021, :]

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Mothers' perception of prenatal counseling following diagnosis of congenital anomalies of the urinary tract.

Dheidan M Alshammari, Eric Dobremez, Alizée Froeliger, Frédéric Coatleven, Luke Harper,

Congenital abnormalities of the genitourinary tract are the most common sonographically identified malformations. Although prenatal diagnosis seldom modifies perinatal management, it can cause significant anxiety in parents. We aimed to assess how parents perceived the prenatal counseling they had received in our institution. Using a questionnaire, we evaluated by phone ... Read more >>

Arch Pediatr (Archives de pediatrie : organe officiel de la Societe francaise de pediatrie)
[2021, :]

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Giant intrathoracic foregut duplication cyst: from prenatal diagnosis to therapeutic management.

T Raia-Barjat, A Scalabre, A Giraud, F Varlet, L Guibaud, M Massoud,

Ultrasound Obstet Gynecol (Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology)
[2021, :]

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Association between maternal antenatal care visits and newborn low birth weight in Bangladesh: a national representative survey

Md. Sabbir Ahmed, Sumaia Sahrin, Fakir Md Yunus,

<ns3:p> <h4>Background: </h4>  Low Birth Weight (LBW) is a global health concern for childhood mortality and morbidity. The objectives of this study were to assess the association between the number of Antenatal Care Visits (ANC) and LBW among Bangladeshi newborns, and to identify the demographic and socio-economic predictors of LBW.  </ns3:p><ns3:p> <h4>Methods: </h4>:</ns3:bold> Our present cross-sectional study is based on the secondary data of the Bangladesh Demography and Health Survey ... Read more >>

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Prenatal diagnosis of a familial 9p12 amplification inherited from a father carrier.

Chih-Ping Chen, Chen-Yu Chen, Schu-Rern Chern, Peih-Shan Wu, Shin-Wen Chen, Fang-Tzu Wu, Yun-Yi Chen, Chen-Chi Lee, Chen-Wen Pan, Wayseen Wang,

<h4>Objective</h4>We present prenatal diagnosis of a familial 9p12 amplification inherited from a father carrier.<h4>Case report</h4>A 38-year-old, gravida 3, para 2, woman underwent amniocentesis at 17 weeks of gestation because of advanced maternal age. Amniocentesis revealed a heteromorphic variant of chromosome 9 with a 9p12 amplification on G-band preparations, but it ... Read more >>

Taiwan J Obstet Gynecol (Taiwanese journal of obstetrics & gynecology)
[2021, 60(5):905-906]

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Effectiveness of multimodal nutrition interventions during pregnancy to achieve 2009 Institute of Medicine gestational weight gain guidelines: a systematic review and meta-analysis.

Andrew R Beauchesne, Kelly Copeland Cara, Jiawen Chen, Qisi Yao, Laura Paige Penkert, Wenfang Yang, Mei Chung,

<h4>Background</h4>In 2009, the Institute of Medicine (IOM) published a revision to its 1990 recommendations on gestational weight gain (GWG). The objective of this review is to update a previous systematic review and meta-analysis to evaluate the effectiveness of nutrition interventions in achieving recommended GWG.<h4>Methods</h4>We conducted updated literature searches in MEDLINE<sup>®</sup> ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1179-1197]

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Congenital syphilis: Need for intensification of antenatal screening and clinician awareness.

Minu P Sunny, C Krishnan, Pr Sabeel Abdulla, M G Geeta,

Congenital syphilis occurs due to trans-placental transmission of <i>Treponema pallidum</i> or rarely, intrapartum contact with infectious lesions. Even though preventable, congenital syphilis occurs sporadically in India, owing to lack of antenatal screening as well as the lack of awareness among clinicians about the burden of syphilis in the community. Since ... Read more >>

Trop Doct (Tropical doctor)
[2021, :494755211041297]

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Prenatal diagnosis, associated findings and postnatal outcome of fetuses with truncus arteriosus communis (TAC).

J S Abel, C Berg, A Geipel, U Gembruch, U Herberg, J Breuer, K Brockmeier, I Gottschalk,

<h4>Purpose</h4>To assess the spectrum of associated anomalies, the intrauterine course, postnatal outcome and management of fetuses with truncus arteriosus communis (TAC) METHODS: All cases of TAC diagnosed prenatally over a period of 8 years were retrospectively collected in two tertiary referral centers. All additional prenatal findings were assessed and correlated with ... Read more >>

Arch Gynecol Obstet (Archives of gynecology and obstetrics)
[2021, :]

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Application of Chromosome Microarray Analysis and Karyotype Analysis in Diagnostic Assessment of Abnormal Down's Syndrome Screening Results

Han Kang, Lingxi Wang, Xingyu Li, Chonglan Gao, Yamei Xie, Yu Hu,

<h4>Background: </h4> Although screening for fetal aneuploidy with the use of cell-free DNA obtained from maternal plasma is highly effective, biomarkers screening is in extensive use in economically underdeveloped areas and poor population. This study aims to explore the application value of chromosomal microarray analysis (CMA) and karyotype analysis in ... Read more >>

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