Full Text Journal Articles about
Angiogenesis

Advertisement

Find full text journal articles






Leukoaraiosis is associated with clinical symptom severity, poor neurological function prognosis and stroke recurrence in mild intracerebral hemorrhage: a prospective multi-center cohort study.

Tian-Qi Xu, Wei-Zhi Lin, Yu-Lan Feng, Fan-Xia Shen, Jie Chen, Wei-Wen Wu, Xiao-Dong Zhu, Lin Gu, Yi Fu,

Leukoaraiosis (LA) results from ischemic injury in small cerebral vessels, which may be attributable to decreased vascular density, reduced cerebrovascular angiogenesis, decreased cerebral blood flow, or microcirculatory dysfunction in the brain. In this study, we enrolled 357 patients with mild intracerebral hemorrhage (ICH) from five hospitals in China and analyzed ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(4):819-823]

Cited: 0 times

View full text PDF listing >>



Fat grafting and platelet-rich plasma in wound healing: a review of histology from animal studies.

Grant S Nolan, Oliver J Smith, Gavin Jell, Afshin Mosahebi,

Stem cells could form the basis of a novel, autologous treatment for chronic wounds like diabetic foot ulcers. Fat grafts contain adipose-derived stem cells (ADSC) but low survival of cells within the grafts is a major limitation. Platelet-rich plasma (PRP) may increase graft survival. This review examines the histology from ... Read more >>

Adipocyte (Adipocyte)
[2021, 10(1):80-90]

Cited: 0 times

View full text PDF listing >>



Advertisement

Myrtenol improves brain damage and promotes angiogenesis in rats with cerebral infarction by activating the ERK1/2 signalling pathway.

Shengming Huang, Zhanguo Tan, Jirui Cai, Zhiping Wang, Yuejun Tian,

<h4>Context</h4>Cerebral ischaemia/reperfusion (I/R) injury has a high disability and fatality worldwide. Myrtenol has protective effects on myocardial I/R injury through antioxidant and anti-apoptotic effects.<h4>Objective</h4>This study investigated the effect of myrtenol on cerebral ischaemia/reperfusion (I/R) injury and the underlying mechanism.<h4>Materials and methods</h4>Cerebral I/R injury was induced in adult Sprague-Dawley rats by ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):584-593]

Cited: 0 times

View full text PDF listing >>



The up-regulation of miR-21 by gastrodin to promote the angiogenesis ability of human umbilical vein endothelial cells by activating the signaling pathway of PI3K/Akt.

Jianli Wang, Minghua Wu,

Studies have shown that gastrodin has a protective effect on blood vessels. The purpose of this study was to investigate the influence of gastrodin on the angiogenesis ability of human umbilical vein endothelial cells (HUVECs) and its mechanism. We found that treatment of HUVECs with 10 µM and 25 µM gastrodin, and ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):5402-5410]

Cited: 0 times

View full text PDF listing >>



Exosomal circular RNA circ_0074673 regulates the proliferation, migration, and angiogenesis of human umbilical vein endothelial cells via the microRNA-1200/MEOX2 axis.

Yan Huang, Bo Liang, Xiangjuan Chen,

Circular RNAs (circRNAs) are implicated in the pathogenesis of gestational diabetes mellitus (GDM). The aim of this study was to investigate the roles and molecular mechanism underlying the effects of circ_0074673 in GDM. Exosomal morphology was visualized by transmission electron microscopy (TEM), while exosomal size and concentration were determined by ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):6782-6792]

Cited: 0 times

View full text PDF listing >>



Trimetazidine ameliorates hindlimb ischaemic damage in type 2 diabetic mice.

Yan Yang, Qinqin Xu, Tao Li, Shiying Shao,

<h4>Background</h4>Ischaemia caused by lower extremity artery stenosis is the main cause of peripheral artery disease (PAD) in patients with diabetes. Trimetazidine (TMZ) has traditionally been used as an anti-ischaemic drug for coronary artery disease. The effect of TMZ on PAD in a diabetic animal model and the underlying molecular mechanisms ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1099-1107]

Cited: 0 times

View full text PDF listing >>



F4, a collagen XIX-derived peptide, inhibits tumor angiogenesis through αvβ3 and α5β1 integrin interaction.

Jean-Baptiste Oudart, Matthieu Villemin, Bertrand Brassart, Christèle Sellier, Christine Terryn, Aurélie Dupont-Deshorgue, Jean Claude Monboisse, François-Xavier Maquart, Laurent Ramont, Sylvie Brassart-Pasco,

We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migration<i>in vitro</i> and cancer progression in a mouse melanoma model. The aim of the present work was to study the anti-angiogenic properties of F4 peptide. We demonstrated that F4 peptide inhibited VEGF-induced pseudo-tube formation on Matrigel by endothelial cells and endothelial ... Read more >>

Cell Adh Migr (Cell adhesion & migration)
[2021, 15(1):215-223]

Cited: 0 times

View full text PDF listing >>



Accelerative effect of topical Zataria multiflora essential oil against infected wound model by modulating inflammation, angiogenesis, and collagen biosynthesis.

Mohammad Reza Farahpour, Sara Sheikh, Elham Kafshdooz, Ali Sonboli,

<h4>Context</h4><i>Zataria multiflora</i> Boiss (Lamiaceae) essential oil (ZME) is believed to be a bactericide herbal medicine and might alleviate negative effects of infection.<h4>Objective</h4>This study evaluates the effects of an ointment prepared from ZME (ZMEO) on infected wounds.<h4>Materials and methods</h4>A full-thickness excisional skin wound was surgically created in each mouse and inoculated ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):1-10]

Cited: 0 times

View full text PDF listing >>



Ultrasound-Stimulated Microbubbles Inhibit Aggressive Phenotypes and Promotes Radiosensitivity of esophageal squamous cell carcinoma.

Jinjun Shi, Chenchun Fu, Xiangyu Su, Shicheng Feng, Sheng Wang,

Ultrasound (US) is reported to improve the delivery efficiency of drugs loading onto large nanoparticles due to the sonoporation effect. Microbubbles (MBs) can be used as contrast agents of US expanding and contracting under low-amplitude US pressure waves. Ultrasound-stimulated microbubbles (USMBs) therapy is a promising option for the treatment of ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):3000-3013]

Cited: 0 times

View full text PDF listing >>



Potential effects of mesenchymal stem cell derived extracellular vesicles and exosomal miRNAs in neurological disorders.

Masako Nakano, Mineko Fujimiya,

Mesenchymal stem cells are multipotent cells that possess anti-inflammatory, anti-apoptotic and immunomodulatory properties. The effects of existing drugs for neurodegenerative disorders such as Alzheimer's disease are limited, thus mesenchymal stem cell therapy has been anticipated as a means of ameliorating neuronal dysfunction. Since mesenchymal stem cells are known to scarcely ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(12):2359-2366]

Cited: 2 times

View full text PDF listing >>



MAGI1 localizes to mature focal adhesion and modulates endothelial cell adhesion, migration and angiogenesis.

Begoña Alday-Parejo, Kedar Ghimire, Oriana Coquoz, Gioele W Albisetti, Luca Tamò, Jelena Zaric, Jimmy Stalin, Curzio Rüegg,

MAGI1 is an intracellular adaptor protein that stabilizes cell junctions and regulates epithelial and endothelial integrity. Here, we report that that in endothelial cells MAGI1 colocalizes with paxillin, β3-integrin, talin 1, tensin 3 and α-4-actinin at mature focal adhesions and actin stress fibers, and regulates their dynamics. Downregulation of MAGI1 ... Read more >>

Cell Adh Migr (Cell adhesion & migration)
[2021, 15(1):126-139]

Cited: 1 time

View full text PDF listing >>



The Inhibitory Effect of Icariin Nanoparticles on Angiogenesis in Pulmonary Fibrosis.

Jiahao Wang, Yuying Sun, Xiangtong Tian,

This study investigated icariin (ICA) nanoparticles on angiogenesis in rats with pulmonary fibrosis and its mechanism. First, icariin solid nanoliposomes (ICA-SLN) were prepared. The <i>in vitro</i>release of icariin nanoparticles was determined using a UV-Vis spectrophotometer, after which the plasma concentration of icariin nanoparticles in rats was determined. The bioavailability of ... Read more >>

J Nanosci Nanotechnol (Journal of nanoscience and nanotechnology)
[2021, 21(11):5429-5435]

Cited: 0 times

View full text PDF listing >>



miR-152-3p aggravates vascular endothelial cell dysfunction by targeting DEAD-box helicase 6 (DDX6) under hypoxia.

Zhongyan Zhao, Chanji Wu, Xiangying He, Eryi Zhao, Shijun Hu, Yeguang Han, Ting Wang, Yanquan Chen, Tao Liu, Shixiong Huang,

Stroke is a main cause of disability and death worldwide, and ischemic stroke accounts for most stroke cases. Recently, microRNAs (miRNAs) have been verified to play critical roles in the development of stroke. Herein, we explored effects of miR-152-3p on vascular endothelial cell functions under hypoxia. Human umbilical vein endothelial ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):4899-4910]

Cited: 0 times

View full text PDF listing >>



δ-tocotrienol suppresses the migration and angiogenesis of trophoblasts in preeclampsia and promotes their apoptosis via miR-429/ ZEB1 axis.

Mei Shi, Xiuyun Chen, Hui Li, Lixia Zheng,

Preeclampsia (PE) is a severe medical disorder during pregnancy and there has been controversy about the effects of vitamin E on PE. This research intended to explore if δ-tocotrienol (δ-TT), an isomer of vitamin E, could impact PE. Preeclamptic and normal placentas were obtained and total RNA was extracted. The ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1861-1873]

Cited: 0 times

View full text PDF listing >>



Oral squamous cell carcinoma (OSCC)-derived exosomal MiR-221 targets and regulates phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1) to promote human umbilical vein endothelial cells migration and tube formation.

Shuqi He, Wu Zhang, Xian Li, Junjie Wang, Xufeng Chen, Yu Chen, Renfa Lai,

Oral squamous cell carcinoma (OSCC) is the most common tumor of the oral cavity. Studies have shown that exosomal miRNAs from cancer cells play an important role in mediating the cellular environment. The objective was to investigate the effect of OSCC-derived exosomes microRNA-221 (miR-221) in OSCC. We used quantitative real-time ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):2164-2174]

Cited: 0 times

View full text PDF listing >>



Vinegar-processed Curcuma phaeocaulis promotes anti-angiogenic activity and reduces toxicity in zebrafish and rat models.

Wan Liao, Yi Chen, Zongping Zhu, Jiao Chen, Tianhui Gao, Boonjai Limsila, Yenchit Techadamrongsin, Lei Wang, Jiali Yu, Chaomei Fu, Rui Li,

<h4>Context</h4>Processing with vinegar could enhance the efficacy and reduce the toxicity of <i>Curcuma phaeocaulis</i> Valeton. (Zingiberaceae), a Chinese herbal medicine with anti-inflammatory and antitumor activities.<h4>Objective</h4>This study investigated the vinegar processing effects by evaluating anti-angiogenic effect and toxicity of <i>C. phaeocaulis</i> through zebrafish and rat models.<h4>Materials and methods</h4>Zebrafish embryos (AB and ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):410-417]

Cited: 0 times

View full text PDF listing >>



All-trans retinoic acid regulating angiopoietins-1 and alleviating extracellular matrix accumulation in interstitial fibrosis rats.

Zhiqing Zhong, Hong-Yan Li, Hongzhen Zhong, Wenshan Lin, Shujun Lin, Tianbiao Zhou,

All-trans retinoic acid (ATRA) is one of essentially active metabolite of vitamin A, and plays an important role in diverse physiological processes, such as cellular growth and function. Renal interstitial fibrosis (RIF) is a common pathological characteristic of chronic renal disease causing end-stage renal disease currently lacking effective treatment. Low ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):658-663]

Cited: 0 times

View full text PDF listing >>



Circular RNA circ_0003028 contributes to tumorigenesis by regulating GOT2 via miR-1298-5p in non-small cell lung cancer.

Hongjun Guan, Changpeng Sun, Yinfeng Gu, Jinjin Li, Jie Ji, Yongxian Zhu,

Non-small cell lung cancer (NSCLC) is a common malignant tumor, with high morbidity and mortality. Circular RNA (circRNA) circ_0003028 was reported to be upregulated in NSCLC. This study is designed to explore the role and mechanism of circ_0003028 on NSCLC progression. In this work, circ_0003028, microRNA-1298-5p (miR-1298-5p), and glutamic oxaloacetic ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):2326-2340]

Cited: 0 times

View full text PDF listing >>



The Role of MiRNA in Cancer: Pathogenesis, Diagnosis, and Treatment.

Erez Uzuner, Gizem Tugçe Ulu, Sevim Beyza Gürler, Yusuf Baran,

Cancer is also determined by the alterations of oncogenes and tumor suppressor genes. These gene expressions can be regulated by microRNAs (miRNA). At this point, researchers focus on addressing two main questions: "How are oncogenes and/or tumor suppressor genes regulated by miRNAs?" and "Which other mechanisms in cancer cells are ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2022, 2257:375-422]

Cited: 0 times

View full text PDF listing >>



PGK1 : An Essential Player in Modulating Tumor Metabolism.

Leslie Duncan, Chloe Shay, Yong Teng,

Phosphoglycerate kinase 1 (PGK1) is the first enzyme in glycolysis to generate a molecule of ATP in the conversion of 1,3-bisphosphoglycerate (1,3-BPG) to 3-phosphoglycerate (3-PG). In addition to the role of glycolysis, PGK-1 acts as a polymerase alpha cofactor protein, with effects on the tricarboxylic acid cycle, DNA replication and ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2022, 2343:57-70]

Cited: 0 times

View full text PDF listing >>



A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts.

Lumin Liao, Bohong Cen, Guoxian Li, Yuanyi Wei, Zhen Wang, Wen Huang, Shuai He, Yawei Yuan, Aimin Ji,

The vascular endothelial growth factor receptor 2 (VEGFR2) is considered to be a pivotal target for anti-tumor therapy against angiogenesis of non-small cell lung cancer (NSCLC). However, effective and low-toxicity targeted therapies to inhibit VEGFR2 are still lacking. Here, biRGD-siVEGFR2 conjugate comprising murine VEGFR2 siRNA and [cyclo(Arg-Gly-Asp-D-Phe-Lys)-Ahx]<sub>2</sub>-Glu-PEG-MAL (biRGD) peptide which ... Read more >>

Drug Deliv (Drug delivery)
[2021, 28(1):1432-1442]

Cited: 0 times

View full text PDF listing >>



The anti-tumor effects of evodiamine on oral squamous cell carcinoma (OSCC) through regulating advanced glycation end products (AGE) / receptor for advanced glycation end products (RAGE) pathway.

Liuyang Ren, Ying Lou, Mingyu Sun,

Evodiamine (EVO) is emerging as a novel anti-tumor drug, which is involved in the inhibition of cell proliferation and apoptosis. High-Mobility Group Box 1 (HMGB1)/RAGE is involved in invasive behavior of OSCC cells and angiogenesis. In this study, we evaluated the potential of EVO in OSCC <i>in vitro</i> and <i>in ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):5985-5995]

Cited: 0 times

View full text PDF listing >>



Comprehensive analysis of angiogenesis subtype of squamous cell carcinoma.

Fanglu Qin, Shenghua Lin, Kun Deng, Junqi Qin, Zhanyu Xu, Liqiang Yuan, Jiangbo Wei, Yu Sun, Tiaozhan Zheng, Shikang Li,

<h4>Background</h4>Squamous cell carcinoma (SCC) is a disease with distinct management complexities as it displays a remarkably heterogeneous molecular subtype. However, the landscape of angiogenesis for SCC is not fully investigated.<h4>Method and materials</h4>The angiogenesis-related subtypes of SCC were established by using the ConsensusClusterPlus package based on angiogenesis-related genes and TCGA data. ... Read more >>

World J Surg Oncol (World journal of surgical oncology)
[2021, 19(1):275]

Cited: 0 times

View full text PDF listing >>



The Role of Venous Endothelial Cells in Developmental and Pathologic Angiogenesis.

Heon-Woo Lee, Yanying Xu, Liqun He, Woosoung Choi, David Gonzalez, Suk-Won Jin, Michael Simons,

<b>Background:</b> Angiogenesis is a dynamic process that involves expansion of a pre-existing vascular network that can occur in a number of physiologic and pathologic settings. Despite its importance, the origin of the new angiogenic vasculature is poorly defined. In particular, the primary subtype of endothelial cells (capillary, venous, arterial) driving ... Read more >>

Circulation (Circulation)
[2021, :]

Cited: 0 times

View full text PDF listing >>



Complement Factor B Mediates Ocular Angiogenesis through Regulating the VEGF Signaling Pathway.

Hannah Murray, Beiying Qiu, Sze Yuan Ho, Xiaomeng Wang,

Complement factor B (CFB), a 95-kDa protein, is a crucial catalytic element of the alternative pathway (AP) of complement. After binding of CFB to C3b, activation of the AP depends on the proteolytic cleavage of CFB by factor D to generate the C3 convertase (C3bBb). The C3 convertase contains the ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2021, 22(17):]

Cited: 0 times

View full text PDF listing >>



Advertisement


Disclaimer

1.3331 s