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Aneurysm

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Identification of potential key pathways, genes and circulating markers in the development of intracranial aneurysm based on weighted gene co-expression network analysis.

Guojia Du, Dangmurenjiafu Geng, Kai Zhou, Yandong Fan, Riqing Su, Qingjiu Zhou, Bo Liu, Serick Duysenbi,

Background: Intracranial aneurysm (IA) is a disease resulted from weak brain control, characterized by local expansion or dilation of brain artery. This study aimed to construct a gene co-expression network by Weighted Gene Correlation Network Analysis (WGCNA) to explore the potential key pathways and genes for the development of IA.Method: ... Read more >>

Artif Cells Nanomed Biotechnol (Artificial cells, nanomedicine, and biotechnology)
[2020, 48(1):999-1007]

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TRPV1 inhibits smooth muscle cell phenotype switching in a mouse model of abdominal aortic aneurysm.

Shuo Wang, Chenhong Jia,

The natural outcome of abdominal aortic aneurysm (AAA) is that of slow progression and ultimate rupture, then a life-threatening hemorrhage consequently. Ruptured AAA is a dramatic catastrophe and constitutes one of the leading causes of acute death in elderly men. However, the mechanism of AAA is still unclear. Transient receptor ... Read more >>

Channels (Austin) (Channels (Austin, Tex.))
[2020, 14(1):59-68]

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Serious cardiovascular adverse events with fluoroquinolones versus other antibiotics: A self-controlled case series analysis.

Sherrie L Aspinall, Nathan P Sylvain, Xinhua Zhao, Rongping Zhang, Diane Dong, Kelly Echevarria, Peter A Glassman, Matthew Bidwell Goetz, Donald R Miller, Francesca E Cunningham,

The objective of this study was to evaluate the association between fluoroquinolone (FQ) use and the occurrence of aortic aneurysm/dissection (AA/AD), acute myocardial infarction (AMI), ventricular arrhythmias (VenA), and all-cause mortality vs other commonly used antibiotics. We conducted a self-controlled case series analysis of patients who experienced the outcomes of ... Read more >>

Pharmacol Res Perspect (Pharmacology research & perspectives)
[2020, 8(6):e00664]

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Clinical factors that influence the occurrence of symptomatic pseudoaneurysms and arteriovenous fistulas after partial nephrectomy: multi-institutional study of renal function outcomes after one year of selective arterial embolization.

Chan Ho Lee, Hong Koo Ha, Ja Yoon Ku, Won Ik Seo, Seock Hwan Choi,

PURPOSE:Renal artery pseudoaneurysms (RAPs) and arteriovenous fistulas (AVFs) are rare but potentially life-threatening complications after partial nephrectomy (PN). Selective arterial embolization (SAE) is an effective method for controlling RAPs/AVFs. We assessed the clinical factors affecting the occurrence of RAPs/AVFs after PN and the effects of SAE on postsurgical renal function. ... Read more >>

Int Braz J Urol (International braz j urol : official journal of the Brazilian Society of Urology)
[2021, 47(1):149-158]

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Bell-bottom technique in iliac branch era: mid-term single stent graft performance.

Gabriele Pagliariccio, Emanuele Gatta, Sara Schiavon, Carlo Grilli Cicilioni, Simona Lattanzi, Elisa Dimitri, Luciano Carbonari,

BACKGROUND:Endovascular abdominal aortic aneurysm repair (EVAR) is considered the primary option for abdominal aortic aneurysm but the management of concomitant wide or aneurysmal iliac arteries (CIAs) is still controversial. METHODS:We retrospectively evaluated mid-term results of patients receiving standard EVAR combined with bell-bottom technique (BBT) using Medtronic Endurant endograft between January ... Read more >>

CVIR Endovasc (CVIR endovascular)
[2020, 3(1):57]

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Endovascular treatment for mycotic aneurysm using pyoktanin- applied devices.

Kei Kazuno, Hajime Kinoshita, Mariko Hori, Takamichi Yosizaki, Atsusi Tamura, Hiroshige Sato, Seiichiro Murata,

BACKGROUND:Mycotic thoracic aortic aneurysm is an extremely rare but serious disease because it can easily rupture and has a high mortality rate. The standard therapy for it comprises graft replacement and debridement using systemic antibiotics; nonetheless, this has a high mortality rate and complications. Endovascular aortic repair is considered a ... Read more >>

CVIR Endovasc (CVIR endovascular)
[2020, 3(1):55]

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Hybrid repair of extensive thoracic aortic aneurysms.

Gabriele Piffaretti, Santi Trimarchi, Guido Gelpi, Claudia Romagnoni, Sandro Ferrarese, Matteo Tozzi, Ruth L Bush, Chiara Lomazzi,

OBJECTIVES:Our goal was to report the midterm results of hybrid treatment of extensive thoracic aortic aneurysm (ETAA) with the completion of thoracic endovascular aortic repair after proximal ascending-arch graft replacement. METHODS:This was a multicentre, observational study. Data were collected prospectively between January 2002 and March 2019 and analysed retrospectively. Inclusion ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2020, 58(5):940-948]

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Significance of aneurysm wall enhancement on high-resolution vessel wall magnetic resonance imaging in clinical management of patients with intracranial aneurysms.

Łukasz Zwarzany, Marcin Sawicki, Wojciech Poncyljusz,

INTRODUCTION:The prevalence of intracranial aneurysms is estimated to be around 3% in the general population. Although these are often incidental findings, they potentially carry the risk of rupture, with all of the devastating consequences of SAH. STATE OF THE ART:Several risk factors of aneurysm rupture have been identified, including aneurysm ... Read more >>

Neurol Neurochir Pol (Neurologia i neurochirurgia polska)
[2020, :]

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Endothelialized silicone aneurysm models for in vitro evaluation of flow diverters.

Alyssa McCulloch, Ashley Turcott, Gabriella Graham, Sergey Frenklakh, Kristen O'Halloran Cardinal,

OBJECTIVE:The goal of this work was to endothelialize silicone aneurysm tubes for use as in vitro models for evaluating endothelial cell interactions with neurovascular devices. The first objective was to establish consistent and confluent endothelial cell linings and to evaluate the silicone vessels over time. The second objective was to ... Read more >>

J Neurointerv Surg (Journal of neurointerventional surgery)
[2020, :]

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Nivolumab-Induced Periaortitis Demonstrated by FDG PET/CT.

Masatoshi Hotta, Go Naka, Ryogo Minamimoto, Yuichiro Takeda, Masayuki Hojo,

A 66-year-old man with a history of non-small cell lung cancer treated with nivolumab underwent contrast-enhanced CT and FDG PET/CT. No recurrence was demonstrated; however, soft-tissue thickening that showed delayed contrast enhancement and FDG uptake was detected around an abdominal aortic aneurysm. After discontinuation of nivolumab, the periaortic lesion disappeared ... Read more >>

Clin Nucl Med (Clinical nuclear medicine)
[2020, 45(11):910-912]

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Comaneci device-assisted embolization of wide-necked carotid aneurysms with an unfavorable ratio.

Juan David Molina-Nuevo, Lorena López-Martínez, María José Pedrosa-Jiménez, Enrique Juliá-Molla, Francisco Hernández-Fernández,

BACKGROUND:Endovascular treatment is the technique of choice for most intracranial aneurysms. However, the treatment of morphologically complex wide-necked aneurysms with an unfavorable anatomy is still a therapeutic challenge. The purpose of the study is to describe the initial experience with the Comaneci embolization assist device for the treatment of wide-necked ... Read more >>

BMC Neurol (BMC neurology)
[2020, 20(1):384]

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Long-term Prognosis After Elective Abdominal Aortic Aneurysm Repair is Poor in Women and Men: The Challenges Remain.

Ruth M A Bulder, Mareia Talvitie, Esther Bastiaannet, Jaap F Hamming, Rebecka Hultgren, Jan H N Lindeman,

OBJECTIVE:To evaluate the impact of changes in elective Abdominal Aortic Aneurysm (AAA) management on life-expectancy of AAA patients. BACKGROUND:Over the past decades AAA repair underwent substantial changes, that is, the introduction of EVAR and implementation of intensified cardiovascular risk management. The question rises to what extent these changes improved longevity ... Read more >>

Ann Surg (Annals of surgery)
[2020, 272(5):773-778]

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Characteristics of patients with ruptured very small intracranial aneurysm sized less than 3 mm.

Gwang-Tae Park, Jong-Hoon Kim, Young-Jin Jung, Chul-Hoon Chang,

Objective:If the size of an intracranial aneurysm is below 3 mm, clinicians rarely treat them because of the low risk of rupture. But subarachnoid hemorrhage (SAH) due to the rupture of very small intracranial aneurysm (VSIA) (saccular aneurysm sized less than 3 mm) may lead to many critical neurological complications. ... Read more >>

J Cerebrovasc Endovasc Neurosurg (Journal of cerebrovascular and endovascular neurosurgery)
[2020, :]

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Surrounding vascular geometry associated with basilar tip aneurysm formation.

Jian Zhang, Anil Can, Pui Man Rosalind Lai, Srinivasan Mukundan, Victor M Castro, Dmitriy Dligach, Sean Finan, Vivian S Gainer, Nancy A Shadick, Guergana Savova, Shawn N Murphy, Tianxi Cai, Scott T Weiss, Rose Du,

Hemodynamic stress is thought to play an important role in the formation of intracranial aneurysms, which is conditioned by the geometry of the surrounding vasculature. Our goal was to identify image-based morphological parameters that were associated with basilar artery tip aneurysms (BTA) in a location-specific manner. Three-dimensional morphological parameters obtained ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):17928]

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Aortic Arch Aneurysm

Samdish Sethi, Utsav Parekh,

An isolated aortic arch aneurysm is an uncommon disease entity and often remains clinically silent, given its indolent growth pattern. Aneurysms of the aortic arch are commonly found in association with aneurysms of the adjacent ascending or descending aorta. The true incidence and natural course are still relatively unknown; however, aneurysms involving ... Read more >>

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Reassessing the Operative Threshold for Abdominal Aortic Aneurysm Repair in the Context of Coronavirus Disease 2019

Brandon McGuinness, Michael Troncone, Lyndon P. James, Steve Bisch, Vikram Iyer,

J Vasc Surg (Journal of vascular surgery)
[2020, 72(5):e345-e345]

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Rupture of sinus of Valsalva aneurysm: case report and review of contemporary literature.

Jean-Luc Duval, Richard Ae Ramsingh, Natasha C Rahaman, Risshi D Rampersad, Gianni D Angelini, Giovanni Teodori,

Sinus of Valsalva aneurysm rupture is a rare condition with a great potential for morbidity and mortality if not promptly diagnosed and managed. We present an unusual non-infected sinus of Valsalva aneurysm rupture in a 47-year-old female. This case report, a likely presentation of a late congenital heart defect, highlights ... Read more >>

Perfusion (Perfusion)
[2020, :267659120966915]

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Embolization with Stent-Assisted Technique for Wide-Necked Extremely Small Intracranial Aneurysm with Diameter no more than 2 mm.

Qi Tian, Wei Dong, Wei Zhang, Zhou Xu, Junmin Wang, Qianxue Chen, Mingchang Li,

OBJECTIVE:To investigate the safety and efficacy of embolization with stent-assisted technique for wide-necked extremely small intracranial aneurysms (ESIAs) with diameter no more than 2 mm. METHODS:From May 2015 through January 2019, 20 wide-necked ESIAs in 19 patients (6 males and 13 females, aged from 38 to 72 years old, average ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2020, 29(12):105388]

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Scoring of Growth of Unruptured Intracranial Aneurysms.

Seppo Juvela,

The purpose was to obtain a reliable scoring for growth of unruptured intracranial aneurysms (UIAs) in a long-term follow-up study from variables known at baseline and to compare it with the ELAPSS (Earlier subarachnoid hemorrhage, Location of the aneurysm, Age > 60 years, Population, Size of the aneurysm, and Shape ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(10):]

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Early major recurrence of cerebral aneurysms after satisfactory initial coiling.

Mohamad Abdalkader, Jean Raymond, Asim Mian, Varun Naragum, Katharine Cronk, Daniel Roy, Alain Weill, Thanh N Nguyen,

BACKGROUND AND PURPOSE:Early major recurrence (EMR) of cerebral aneurysms treated by coiling has not been investigated. The purpose of this study is to characterize the frequency and risk factors of this phenomenon. MATERIALS AND METHODS:A retrospective review was performed of consecutive patients who presented with ruptured and unruptured cerebral aneurysms ... Read more >>

Interv Neuroradiol (Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences)
[2020, :1591019920968370]

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Pseudoaneurysm following hamstring tendon harvest in arthroscopic anterior cruciate ligament reconstruction: a case report.

Chung-Wei Ho, Shih-Han Lee, Shen-Han Wu, Chun-Yu Lin, Chian-Her Lee, Jia-Lin Wu,

BACKGROUND:Vascular injury is a very rare complication following arthroscopic knee surgery. This is the first report of pseudoaneurysm at the saphenous branch of the descending genicular artery complicating semitendinosus tendon harvest in arthroscopic anterior cruciate ligament reconstruction. CASE PRESENTATION:A 19-year-old male had developed large ecchymosis, focal swelling and tenderness around ... Read more >>

BMC Musculoskelet Disord (BMC musculoskeletal disorders)
[2020, 21(1):697]

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The Association Between Thoracoabdominal Aneurysm Extent and Mortality after Complex Endovascular Repair.

Ryan T Heslin, Danielle C Sutzko, John Axley, Zdenek Novak, Victoria J Aucoin, Mark A Patterson, Benjamin J Pearce, Marc A Passman, Salvatore T Scali, Graeme E McFarland, Adam W Beck,

OBJECTIVE:Traditional open surgical repair of thoracoabdominal aneurysms (TAAA) historically carries 30-day mortality rates from 6% to 20%, depending on Crawford anatomic extent. While short-term survival is important, long-term survival is essential for patients to benefit from these often elective and potentially morbid procedures. Aneurysm extent impacts the long-term survival after ... Read more >>

J Vasc Surg (Journal of vascular surgery)
[2020, :]

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Survival, Dependency, and Health-Related Quality of Life in Patients With Ruptured Intracranial Aneurysm: 10-Year Follow-up of the United Kingdom Cohort of the International Subarachnoid Aneurysm Trial.

Xinyang Hua, Alastair Gray, Jane Wolstenholme, Philip Clarke, Andrew J Molyneux, Richard S C Kerr, Alison Clarke, Mary Sneade, Oliver Rivero-Arias,

BACKGROUND:Previous analyses of the International Subarachnoid Aneurysm Trial (ISAT) cohort have reported on clinical outcomes after treatment of a ruptured intracranial aneurysm with either neurosurgical clipping or endovascular coiling. OBJECTIVE:To evaluate the long-term quality-adjusted life years (QALYs) gained of endovascular coiling compare to neurosurgical clipping in the UK cohort of ... Read more >>

Neurosurgery (Neurosurgery)
[2020, :]

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Diffuse cerebral angiomatosis associated to basilar apex aneurysm.

Giuseppe Emmanuele Umana, Angelo Spitaleri, Marco Fricia, Ignazio Indorato, Giovanni Federico Nicoletti, Salvatore Cicero, Gianluca Scalia,

BACKGROUND:Diffuse cerebral angiomatosis (DCA) is a diffuse infiltration of normal brain by complex vascular structures. It differs from arteriovenous malformations (AVMs) that are composed of a nidus of vessels through which arteriovenous shunting occurs without interposed functional brain parenchyma. A rare subgroup of AVMs is diffuse with no recognizable nidus ... Read more >>

Br J Neurosurg (British journal of neurosurgery)
[2020, :1-5]

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Variants of Focal Adhesion Scaffold Genes Cause Thoracic Aortic Aneurysm.

Yang Li, Shijuan Gao, Yingchun Han, Li Song, Yu Kong, Yao Jiao, Shan Huang, Jie Du, Yulin Li,

Rationale: Thoracic aortic aneurysm (TAA) leads to substantial mortality worldwide. Familial and syndromic TAAs are highly correlated with genetics. However, the incidence of sporadic isolated TAA (iTAA) is much higher, and the genetic contribution is not yet clear. Objective: Here, we examined the genetic characteristics of sporadic iTAA. Methods and ... Read more >>

Circ Res (Circulation research)
[2020, :]

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