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Anemia of Prematurity

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Preterm birth determinants among newborns at six public hospitals in Northeast Amhara, Ethiopia: unmatched case-control study

Habtamu Mekonnen, Mesfin Shiferaw, Nigusie Tebeje,

<title>Abstract</title> <p> Background Preterm birth is a global public health problem. Worldwide, every year about 15 million newborns are born preterm and about 1.1 million of them die due to complications related to prematurity. More than 81% of preterm births were in Asia and Sub-Saharan Africa. Nowadays, preterm ... Read more >>

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Effectiveness of Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria and Adverse Birth Outcomes in Pregnant Women.

Eulambius M Mlugu, Omary Minzi, Muhammad Asghar, Anna Färnert, Appolinary A R Kamuhabwa, Eleni Aklillu,

Effectiveness of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) for prevention of malaria and adverse birth outcomes can be compromised by parasites-resistance to sulfadoxine-pyrimethamine. This study prospectively evaluated the effectiveness of IPTp-SP in Southeast Tanzania. From January 2017 to May 2019, HIV-negative and malaria-negative (mRDT) pregnant women attending their ... Read more >>

Pathogens (Pathogens (Basel, Switzerland))
[2020, 9(3):]

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Post-traumatic stress disorder and association with low birth weight in displaced population following conflict in Malakand division, Pakistan: a case control study.

Haroon Ur Rashid, Muhammad Naseem Khan, Ayesha Imtiaz, Naeem Ullah, Mukesh Dherani, Atif Rahman,

BACKGROUND:The northern part of the province of Khyber Pakhtunkhwa in Pakistan experienced armed conflict since September 2007 till the autumn of 2011. Conflict involved widespread insurgency activity and military intervention including in 2009 internally displacing the 2.5 million people of the valley of Swat to live in camps, with relatives, ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2020, 20(1):166]

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PDGFR-β and kidney fibrosis.

Alberto Ortiz,

Chronic kidney disease (CKD) is one of the fastest growing global causes of death, estimated to rank among the top five by 2040 (Foreman et al, 2018). This illustrates current pitfalls in diagnosis and management of CKD. Advanced CKD requires renal function replacement by dialysis or transplantation. However, earlier CKD stages, ... Read more >>

EMBO Mol Med (EMBO molecular medicine)
[2020, 12(3):e11729]

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Maternal Characteristics and Obstetric and Neonatal Outcomes of Singleton Pregnancies Among Adolescents.

Evrim Kiray Baş, Ali Bülbül, Sinan Uslu, Vedat Baş, Gizem Kara Elitok, Umut Zubarioğlu,

BACKGROUND Adolescent pregnancy remains a global public health issue with serious implications on maternal and child health, particularly in developing countries The aim of this study was to investigate maternal characteristics and obstetric and neonatal outcomes of singleton pregnancies among adolescents. MATERIAL AND METHODS A total of 241 adolescent women ... Read more >>

Med. Sci. Monit. (Medical science monitor : international medical journal of experimental and clinical research)
[2020, 26:e919922]

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Hemoglobin levels and anemia evaluation among pregnant women in the remote and rural high lands of mid-western Nepal: a hospital based study.

Deepak Sharma, Kapil Amgain, Prem Prasad Panta, Bishal Pokhrel,

BACKGROUND:Anemia though is a major risk factor for unfavorable pregnancy outcomes; no previous studies have yet described the hemoglobin (Hb) concentrations and anemia prevalence among pregnant women of remote mid western highlands of Nepal where the aggravating factors that increase the risk of anemia are very common. In addition, the ... Read more >>

BMC Pregnancy Childbirth (BMC Pregnancy and Childbirth)
[2020, 20(1):182]

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Impact of the volume of blood collected by phlebotomy on transfusion requirements in preterm infants with birth weight of less than 1500 g. A quasi-experimental study.

Pablo H Brener Dik, María F Galletti, María P Carrascal, Alejandra De Gregorio, Leandro Burgos Pratx, Ana M Gómez Saldaño, Gonzalo L Mariani,

INTRODUCTION:Anemia is a complication in very low birth weight (VLBW) infants, and lab tests are a predominant risk factor. At least one red blood cell transfusion is given in more than 50 % of cases. Transfusions are associated with a higher risk for infections, intracranial hemorrhage, necrotizing enterocolitis, and bronchopulmonary ... Read more >>

Arch Argent Pediatr (Archivos argentinos de pediatria)
[2020, 118(2):109-116]

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Potential new tool for anemia screening: An evaluation of the performance and usability of the TrueHb Hemometer.

Megan Parker, Kelsey Barrett, Maria Kahn, Dominira Saul, Pooja Bansil, Charlotte Tawiah, Nicole Advani, Stephanie Zobrist, Tala de Los Santos, Emily Gerth-Guyette,

In low- and middle-income countries, many women experience anemia during pregnancy due to insufficient dietary intake of key micronutrients, parasitic infections, hemoglobinopathies, and chronic infections. Maternal anemia increases perinatal risks for both mothers and infants, and slow progress to reduce the prevalence may be due in part to the lack ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0230333]

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Disability and Pregnancy: A Cross-Federal Agency Collaboration to Collect Population-Based Data About Experiences Around the Time of Pregnancy.

Denise V D'Angelo, Alison Cernich, Leslie Harrison, Katie Kortsmit, JoAnn M Thierry, Suzanne Folger, Lee Warner,

Many reproductive-aged women with a disability can achieve successful healthy pregnancies; however, they may face challenges accessing prenatal and postpartum care and finding providers who are knowledgeable about their specific condition. Depending on the nature of the disability, some women may also be at increased risk for adverse maternal and ... Read more >>

J Womens Health (Larchmt) (Journal of women's health (2002))
[2020, 29(3):291-296]

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FANCL gene mutations in premature ovarian insufficiency.

Yajuan Yang, Ting Guo, Ran Liu, Hanni Ke, Weiwei Xu, Shidou Zhao, Yingying Qin,

The Fanconi anemia (FA) pathway is mainly involved in DNA interstrand crosslinks (ICLs) repair in the genome. Several FA genes, including FANCD1/BRCA2, FANCM, and FANCU/XRCC2, have been identified as causative genes for premature ovary insufficiency (POI). Fanconi anemia group L protein (FANCL) cooperates with FANCT/UBE2T to ubiquitinate the FANCI-D2 dimer, ... Read more >>

Hum. Mutat. (Human mutation)
[2020, :]

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Vitamin and Mineral Supplementation During Pregnancy on Maternal, Birth, Child Health and Development Outcomes in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis.

Christina Oh, Emily C Keats, Zulfiqar A Bhutta,

Almost two billion people are deficient in key vitamins and minerals, mostly women and children in low- and middle-income countries (LMICs). Deficiencies worsen during pregnancy due to increased energy and nutritional demands, causing adverse outcomes in mother and child, but could be mitigated by interventions like micronutrient supplementation. To our ... Read more >>

Nutrients (Nutrients)
[2020, 12(2):]

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Should young children with human leukocyte antigen identical sibling donor be offered hematopoietic cell transplantation?

Lakshmanan Krishnamurti,

Availability of an HLA-identical sibling donor raises the question "should young children with an HLA identical sibling donor be considered for hematopoietic cell transplantation (HCT) even before they manifest severe clinical presentations of sickle cell disease (SCD)?" The overall survival (OS) and event free survival (EFS) following HCT from an ... Read more >>

Hematol Oncol Stem Cell Ther (Hematology/oncology and stem cell therapy)
[2020, :]

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Incidence, risk factors and consequences of preterm birth – findings from a multicentric observational study in Nepal

Ashish Kc, Abhishek Gurung, Johan Wrammert, Avinash Sunny, Rejina Gurung, Netra Rana, Yuba Basaula, Prajwal Paudel, Amrit Pokhrel,

<title>Abstract</title> <p> Background: Preterm birth is a worldwide epidemic and a leading cause of neonatal mortality. In this study, we aimed to evaluate the incidence, risk factors and consequences of preterm birth in Nepal. Methods: This was an observational study conducted in 12 public hospitals of Nepal. All ... Read more >>

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Adherence level of Health care Providers to first visit antenatal care guideline and its effect on perinatal outcome in Tigray public Health institutions, 2017/18: Cohort study

Abera Melkamu, Tesfay Hailu, Brhane G/micheal, Hadgay Adhanu, Mhiret-AB Reda, Assefa Kebede, Tsige Hailu, Hailemaryam Kahsa, Haftu Gebru, Alemayehu Kahsay,

<title>Abstract</title> <p> Background: Antenatal care is one of the medical services delivered to pregnant women for the safety of the mother and the neonate. Guidelines are developed to ensure quality, uniformity and consistency of care for clients. One of the guidelines is focused antenatal care. Despite this fact, ... Read more >>

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Impact of Dietary Interventions during Pregnancy on Maternal, Neonatal, and Child Outcomes in Low- and Middle-Income Countries.

Zohra S Lassi, Zahra A Padhani, Amna Rabbani, Fahad Rind, Rehana A Salam, Jai K Das, Zulfiqar A Bhutta,

Optimal nutrition plays a crucial role in pregnancy. Maternal malnutrition is a risk factor for maternal, fetal, and neonatal complications and is more prevalent in low and middle-income countries (LMICs). This review aims to study the effectiveness of antenatal macronutrient nutritional interventions on maternal, neonatal, and child outcomes. We searched ... Read more >>

Nutrients (Nutrients)
[2020, 12(2):]

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Determinants of Preterm Birth among Women Who Gave Birth in Amhara Region Referral Hospitals, Northern Ethiopia, 2018: Institutional Based Case Control Study.

Abebayehu Melesew Mekuriyaw, Muhabaw Shumye Mihret, Ayenew Engida Yismaw,

Background:Preterm birth refers to a birth of a baby before 37 completed weeks of gestation and after fetal viability. It is now the leading cause of new born deaths. Although identifying its common risk factors is mandatory to decrease preterm birth and thereby neonatal deaths, there was a dearth of ... Read more >>

Int J Pediatr (International Journal of Pediatrics)
[2020, 2020:1854073]

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Epidemiology, treatment and outcomes of anemia in premature newborn babies in Centre Hospitalierd’Essos, Yaounde, Cameroon.

Anne NjomNlend, Larissa Ahanda, Arsene Sandie, Paul Ndombo,

<title>Abstract</title> <p> <bold>Introduction</bold> At birth, all newborns experience a decrease in hemoglobin levels; this decrease is more emphasized in premature babies. The objective of this work was to study the epidemiological, therapeutic and outcomesof anemia amongst preterm birthsin a reference hospital in Cameroon. <bold>Methodology</bold> This was a two-year ... Read more >>

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Determinants of preterm birth among mothers who gave birth in East Africa: systematic review and meta-analysis.

Tariku Laelago, Tadele Yohannes, Gulima Tsige,

BACKGROUND:Preterm birth (PTB) can be caused by different factors. The factors can be classified into different categories: socio demographic, obstetric, reproductive health, medical, behavioral and nutritional related. The objective of this review was identifying determinants of PTB among mothers who gave birth in East African countries. METHODS:We have searched the ... Read more >>

Ital J Pediatr (Italian journal of pediatrics)
[2020, 46(1):10]

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Perinatal Management of Bart's Hemoglobinopathy: Paradoxical Effects of Intrauterine, Transplacental, and Partial Exchange Transfusions.

Mark Curran, Michel Mikhael, Wang-Dar Sun, Jina Lim, Anna Leung, Gira Morchi, Ramen H Chmait,

We describe a fetus at 24 3/7 weeks' gestation that showed ultrasound evidence of anemia, hydrops, and severe growth restriction. Both parents were known to be cis heterozygous carriers for SEA α-thalassemia deletion (αα/-). Cordocentesis confirmed fetal anemia and homozygous α-thalassemia (-/-) in the fetus. Fetal intrauterine transfusions corrected the ... Read more >>

AJP Rep (AJP reports)
[2020, 10(1):e11-e14]

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Adherence level of Health care Providers to first visit antenatal care guideline and its effect on perinatal outcome in Tigray public Health institutions, 2017/18: Cohort study

Abera Melkamu, Tesfay Hailu, Brhane G/micheal, Hadgay Adhanu, Mhiret-AB Reda, Assefa Kebede, Tsige Hailu, Hailemaryam Kahsa, Haftu Gebru, Alemayehu Kahsay,

<title>Abstract</title> <p> <bold>Background:</bold> Antenatal care is one of the medical services delivered to pregnant women for the safety of the mother and the neonate. Guidelines are developed to ensure quality, uniformity and consistency of care for clients. One of the guidelines is focused antenatal care. Despite this fact, ... Read more >>

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Multiple Chorangioma Following Long-Term Secondary Infertility: A Rare Case Report and Review of Pathologic Differential Diagnosis.

Mojgan Akbarzadeh-Jahromi, Neda Soleimani, Sahand Mohammadzadeh,

Chorangioma (placental hemangioma) is a benign non-trophoblastic neoplasm of the placenta. Small chorangiomas are usually asymptomatic, but the giant and multiple ones rarely have a favorable outcome. We report a case of 29 weeks of gestational age (after long-term secondary infertility) with premature labor pain and undiagnosed multiple chorangioma leading ... Read more >>

Int Med Case Rep J (International medical case reports journal)
[2019, 12:383-387]

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Child development, physiological stress and survival expectancy in prehistoric fisher-hunter-gatherers from the Jabuticabeira II shell mound, South Coast of Brazil.

Luis Pezo-Lanfranco, José Filippini, Marina Di Giusto, Cecília Petronilho, Veronica Wesolowski, Paulo DeBlasis, Sabine Eggers,

In this study, we shed light on the interdependency of child growth, morbidity and life expectancy in the fisher-hunter-gatherers of the Jabuticabeira II shell mound (1214-830 cal B.C.E. - 118-413 cal C.E.) located at the South Coast of Brazil. We test the underlying causes of heterogeneity in frailty and selective ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0229684]

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Maternal and Perinatal Morbidity and Mortality Associated With Anemia in Pregnancy.

Catherine Smith, Flora Teng, Emma Branch, Scally Chu, K S Joseph,

OBJECTIVE:To estimate the incidence of anemia in pregnancy and compare the maternal and perinatal outcomes of women with and without anemia. METHODS:We conducted a population-based retrospective cohort study on all pregnant women in British Columbia who had a live birth or stillbirth at or after 20 weeks of gestation between ... Read more >>

Obstet Gynecol (Obstetrics and gynecology)
[2019, 134(6):1234-1244]

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Iron Deficiency in Pregnancy.

Michael K Georgieff,

Iron is essential for the function of all cells through its roles in oxygen delivery, electron transport, and enzymatic activity. Cells with high metabolic rates require more iron and are at greater risk for dysfunction during iron deficiency. Iron requirements during pregnancy increase dramatically as the mother's blood volume expands ... Read more >>

Am. J. Obstet. Gynecol. (American journal of obstetrics and gynecology)
[2020, :]

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Management of Restless Legs Syndrome in Pregnancy and Lactation.

Marjan Jahani Kondori, Bhanu Prakash Kolla, Katherine M Moore, Meghna P Mansukhani,

Restless legs syndrome (RLS) affects about 20% of all pregnant women. RLS symptoms are usually moderate to severe in intensity during pregnancy and can result in insomnia, depression, and other adverse outcomes. Although iron deficiency has been implicated as a potential etiological factor, other mechanisms can also play a role. ... Read more >>

J Prim Care Community Health (Journal of primary care & community health)
[2020, 11:2150132720905950]

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