Full Text Journal Articles about
Altitude Illness Cerebral Syndromes

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Health, income and poverty: evidence from China's rural household survey.

Yang Zhou, Yuanzhi Guo, Yansui Liu,

BACKGROUND:Understanding the health status of the poor households and the influence of unhealthy on their income can provide some vital insights into the effectiveness and appropriateness of poverty reduction solutions. METHODS:Based on a nationwide cross-sectional survey of 29,712 rural poor households, this study systematically investigated the causes of poverty and ... Read more >>

Int J Equity Health (International journal for equity in health)
[2020, 19(1):36]

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Pediatric critical illness associated cerebral microhemorrhages.

Anna Misyail Abdul Rashid, Norafida Bahari, Mohamad Syafeeq Faeez Md Noh,

eNeurologicalSci (eNeurologicalSci)
[2020, 18:100221]

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Association of EPAS1 and PPARA Gene Polymorphisms with High-Altitude Headache in Chinese Han Population.

Yang Shen, Jihang Zhang, Jie Yang, Chuan Liu, Shizhu Bian, Chen Zhang, Jie Yu, Xubin Gao, Lan Huang,

Background:High-altitude headache (HAH) is the most common complication after high-altitude exposure. Hypoxia-inducible factor- (HIF-) related genes have been confirmed to contribute to high-altitude acclimatization. We aim to investigate a possible association between HIF-related genes and HAH in the Chinese Han population. Methods:In total, 580 healthy Chinese Han volunteers were recruited ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:1593068]

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The prevalence of hypoxemia among pediatric and adult patients presenting to healthcare facilities in low- and middle-income countries: protocol for a systematic review and meta-analysis.

Felix Lam, Rami Subhi, Jason Houdek, Kate Schroder, Audrey Battu, Hamish Graham,

BackgroundHypoxemia is a severe condition associated with high rates of mortality, particularly in low- and middle-income countries (LMICs) with poor access to oxygen therapy. Despite its clinical significance, there have been few studies to describe the burden of hypoxemia. Thus, the primary objective of this study is to systematically describe ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9:]

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Metabolic syndrome in native populations living at high altitude: a cross-sectional survey in Derong, China.

Xiaofei Huang, Yongbo Hu, Longqi Du, Xiaolong Lin, Wenli Wu, Lijun Fan, Libo Li, Xiaowei Zhong, Qiyong Gong, Li Gao, Weihong Kuang,

OBJECTIVE:The metabolic syndrome is a major risk factor for cardiovascular disease. Little information exists on the prevalence of the metabolic syndrome at high-altitude areas in China. We aimed to estimate the prevalence of metabolic syndrome and its individual components at high altitude. METHODS:A cross-sectional survey of 5053 adults living in ... Read more >>

BMJ Open (BMJ open)
[2020, 10(1):e032840]

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Brain functional changes in tibetan with obstructive sleep apnea hypopnea syndrome: A resting state fMRI study.

Dongjie Kang, Zongyuan Qin, Wen Wang, Yun Zheng, Huiying Hu, Yuanyuan Bao, Haihua Bao,

Tibetan is a major ethnic group living on the Qinghai-Tibet Plateau in China. Due to their high-altitude hypoxia environment, sleeping disorder and obstructive sleep apnea hypopnea syndrome (OSAHS) are more prone to occur. In this study, we investigated the brain structural and functional differences between Tibetans OSAHS patients and Tibetans ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(7):e18957]

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High-altitude illness: Management approach.

Gökhan Aksel, Şeref Kerem Çorbacıoğlu, Can Özen,

In high altitudes, usually above 2500 m, travelers are faced with decreased partial pressure of oxygen along with decreased barometric pressure. High-altitude illness, a syndrome of acute mountain sickness, high-altitude cerebral edema and high-altitude pulmonary edema, occurs due to the hypobaric hypoxia when there is inadequate acclimatization. This review provides detailed ... Read more >>

Turk J Emerg Med (Turkish journal of emergency medicine)
[2019, 19(4):121-126]

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Optic nerve sheath diameter: present and future perspectives for neurologists and critical care physicians.

Piergiorgio Lochner, Marek Czosnyka, Andrea Naldi, Epameinondas Lyros, Paolo Pelosi, Shrey Mathur, Klaus Fassbender, Chiara Robba,

BACKGROUND:Estimation of intracranial pressure (ICP) may be helpful in the management of neurological critically ill patients. It has been shown that ultrasonography of the optic nerve sheath diameter (ONSD) is a reliable tool for non-invasive estimation of increased intracranial pressure (ICP) at hospital admission or in intensive care. Less is ... Read more >>

Neurol. Sci. (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology)
[2019, 40(12):2447-2457]

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Recurrent Stroke-Like Symptoms After Cesarean Section Deliveries in a Female Patient With X-Linked Charcot-Marie-Tooth Type 1.

Qu Li, Chen Chen, Yan Ren, Xu Liu,

Background: X-linked Charcot-Marie-Tooth type 1 (CMTX1) is the second most frequent form of CMT, which is caused by mutations in the gap junction beta 1 gene (GJB1) coding for connexin 32 protein. In addition to typical peripheral neuropathy, central nervous system (CNS) involvement in patients with CMTX1 has been reported ... Read more >>

Front Neurol (Frontiers in neurology)
[2020, 11:8]

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Mountain sickness with delayed signal changes in the corpus callosum on magnetic resonance imaging: a case report.

Youichi Yanagawa, Shunsuke Madokoro, Tamaki Matsunami, Hiroki Nagasawa, Ikuto Takeuchi, Kei Jitsuiki, Norihito Takahashi, Hiromichi Ohsaka, Kouhei Ishikawa, Kazuhiko Omori,

A 32-year-old man started building a wooden desk atop Mount Fuji at an altitude of 3,776 m. Over the course of the second day, he developed lassitude and cough and experienced a headache that night; however, he continued to work. He was transported to our hospital with an altered level ... Read more >>

J Rural Med (Journal of rural medicine : JRM)
[2019, 14(2):253-257]

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Mild encephalitis/encephalopathy with a reversible splenial lesion secondary to encephalitis complicated by hyponatremia: A case report and literature review.

Bi-Chuan Shi, Jiao Li, Ji-Wei Jiang, Mei-Xin Li, Jian Zhang, Xiu-Li Shang,

RATIONALE:Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is an infection-associated encephalitis/encephalopathy syndrome that is predominately caused by a virus. MERS has no direct association with central nervous system (CNS) infections or inflammation. Non-CNS infections may cause reversible lesion in the splenium of corpus callosum. Recently, there have been reports ... Read more >>

Medicine (Baltimore) (Medicine)
[2019, 98(47):e17982]

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Intraocular Pressure Changes of Healthy Lowlanders at Different Altitude Levels: A Systematic Review and Meta-Analysis.

Yiquan Yang, Yuan Xie, Yunxiao Sun, Kai Cao, Shuning Li, Sujie Fan, Lu Huang, Shizheng Wu, Ningli Wang,

Background: High altitude, characterized by hypobaric hypoxia, low temperature, and intensive ultraviolet radiation, is identifiably one of the examples of scientific enquiry into aviation and space analogs. However, little is known about the ocular physiological response, especially intraocular pressure (IOP) changes at high altitude. Objectives: This study aimed to systematically ... Read more >>

Front Physiol (Frontiers in Physiology)
[2019, 10:1366]

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Continuous professional development: elevating sleep andbreathing disorder education in Europe.

Sophia E Schiza, Winfried Randerath, Manuel Sánchez-de-la-Torre, Andrea Aliverti, MariaR Bonsignore, Anita K Simonds, Pierantonio Laveneziana,

The @EuroRespSoc launches a new sleep and breathing disorders continuous professional development programme http://bit.ly/30PU01P. ... Read more >>

Breathe (Sheff) (Breathe (Sheffield, England))
[2020, 16(1):190336]

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A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease.

Gustavo Provensi, Fabrizio Carta, Alessio Nocentini, Claudiu T Supuran, Fiorella Casamenti, M Beatrice Passani, Silvia Fossati,

The increase in the incidence of neurodegenerative diseases, in particular Alzheimer's Disease (AD), is a consequence of the world's population aging but unfortunately, existing treatments are only effective at delaying some of the symptoms and for a limited time. Despite huge efforts by both academic researchers and pharmaceutical companies, no ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2019, 20(19):]

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Grief-induced reversible cerebral vasoconstriction syndrome (RCVS).

Pooja Rao, Michael Francis McCullough, Jessica Stevens, Matthew A Edwardson,

Stress is under-recognised as a potential causative factor for reversible cerebral vasoconstriction syndrome (RCVS). Here we present a case of RCVS occurring during a time of extreme emotional duress. A 46-year-old female patient with medical history of bipolar disorder developed a severe headache during her father's funeral. The following day ... Read more >>

BMJ Case Rep (BMJ case reports)
[2020, 13(1):]

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Assessing the Microcirculation With Handheld Vital Microscopy in Critically Ill Neonates and Children: Evolution of the Technique and Its Potential for Critical Care.

Özge Erdem, Can Ince, Dick Tibboel, Jan Willem Kuiper,

Assuring adequate tissue oxygenation in the critically ill, but still developing child is challenging. Conventional hemodynamic monitoring techniques fall short in assessing tissue oxygenation as these are directed at the macrocirculation and indirect surrogates of tissue oxygenation. The introduction of handheld vital microscopy (HVM) has allowed for the direct visualization ... Read more >>

Front Pediatr (Frontiers in Pediatrics)
[2019, 7:273]

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Interventions for preventing high altitude illness: Part 3. Miscellaneous and non-pharmacological interventions.

Daniel Molano Franco, Víctor H Nieto Estrada, Alejandro G Gonzalez Garay, Arturo J Martí-Carvajal, Ingrid Arevalo-Rodriguez,

BACKGROUND:High altitude illness (HAI) is a term used to describe a group of mainly cerebral and pulmonary syndromes that can occur during travel to elevations above 2500 metres (˜ 8200 feet). Acute mountain sickness (AMS), high altitude cerebral oedema (HACE), and high altitude pulmonary oedema (HAPE) are reported as potential ... Read more >>

Cochrane Database Syst Rev (The Cochrane database of systematic reviews)
[2019, 4:CD013315]

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Sex-based differences in the prevalence of acute mountain sickness: a meta-analysis.

Yun-Peng Hou, Jia-Lin Wu, Chao Tan, Yu Chen, Rui Guo, Yong-Jun Luo,

BACKGROUND:When lowlanders rapidly ascend to altitudes > 2500 m, they may develop acute mountain sickness (AMS). The individual susceptibility, ascending velocity, time spent at altitude, activity levels and altitude reached are considered risk factors for AMS. However, it is not clear whether sex is a risk factor. The results have been inconclusive. ... Read more >>

Mil Med Res (Military Medical Research)
[2019, 6(1):38]

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Acute normobaric hypoxia does not affect the simultaneous exercise-induced increase in circulating BDNF and GDNF in young healthy men: A feasibility study.

Zofia Piotrowicz, Małgorzata Chalimoniuk, Kamila Płoszczyca K, Miłosz Czuba, Józef Langfort,

Physical exercise has a neuromodulatory effect on the central nervous system (CNS) partially by modifying expression of neuropeptides produced and secreted by neurons and glial cells, among which the best examined are brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF). Because both neurotrophins can cross the brain-blood ... Read more >>

PLoS ONE (PloS one)
[2019, 14(10):e0224207]

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Iron and Sphingolipids as Common Players of (Mal)Adaptation to Hypoxia in Pulmonary Diseases.

Sara Ottolenghi, Aida Zulueta, Anna Caretti,

Hypoxia, or lack of oxygen, can occur in both physiological (high altitude) and pathological conditions (respiratory diseases). In this narrative review, we introduce high altitude pulmonary edema (HAPE), acute respiratory distress syndrome (ARDS), Chronic Obstructive Pulmonary Disease (COPD), and Cystic Fibrosis (CF) as examples of maladaptation to hypoxia, and highlight ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(1):]

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Traveling With Cancer: A Guide for Oncologists in the Modern World.

Sharon Heng, Brett Hughes, Michael Hibbert, Mustafa Khasraw, Zarnie Lwin,

PURPOSE:Travel for patients with cancer has become more achievable because of gains in quality of life and overall survival. The risk assessment of these patients is complex, and there is a paucity of data to which clinicians can refer. We present the challenges of traveling with cancer and a review ... Read more >>

J Glob Oncol (Journal of global oncology)
[2019, 5:1-10]

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Hypoxaemia in hospitalised children and neonates: A prospective cohort study in Nigerian secondary-level hospitals.

Hamish Graham, Ayobami A Bakare, Adejumoke I Ayede, Oladapo B Oyewole, Amy Gray, David Peel, Barbara McPake, Eleanor Neal, Shamim A Qazi, Rasa Izadnegahdar, Trevor Duke, Adegoke G Falade,

Background:Hypoxaemia is a common complication of pneumonia and a major risk factor for death, but less is known about hypoxaemia in other common conditions. We evaluated the epidemiology of hypoxaemia and oxygen use in hospitalised neonates and children in Nigeria. Methods:We conducted a prospective cohort study among neonates and children ... Read more >>

EClinicalMedicine (EClinicalMedicine)
[2019, 16:51-63]

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Changes in Heart Rate and Rhythm During a Crossover Study of Simulated Commercial Flight in Older and Vulnerable Participants.

Mark J Meyer, Irina Mordukhovich, Gregory A Wellenius, Murray A Mittleman, John P McCracken, Brent A Coull, Eileen McNeely,

Objectives: Elderly passengers and those with preexisting disease are flying with increasing frequency and in-flight cardiac emergencies are a more frequent occurrence. We conducted a study of the physiological effects of simulated cabin altitudes and resulting lower oxygen levels among such passengers. Methods: We monitored 41 participants in a hypobaric ... Read more >>

Front Physiol (Frontiers in Physiology)
[2019, 10:1339]

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Factors associated with cerebral edema in children under 5 years of age admitted in an intensive care unit and their outcome.

Shamin Islam, Monira Sarmin, Tahmeed Ahmed, Farzana Afroze, Mohammod Jobayer Chisti,

Objective:We aimed to evaluate risk factors and outcome of cerebral edema in children with diarrhea. Methods:In this retrospective chart analysis, data of all diarrheal children under 5 years of age having convulsion and admitted in intensive care unit were retrieved from an electronic medical record system of Dhaka Hospital of ... Read more >>

SAGE Open Med (SAGE Open Medicine)
[2019, 7:2050312119874622]

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New metric of hypoxic dose predicts altitude acclimatization status following various ascent profiles.

Beth A Beidleman, Charles S Fulco, Allen Cymerman, Janet E Staab, Mark J Buller, Stephen R Muza,

Medical personnel need practical guidelines on how to construct high altitude ascents to induce altitude acclimatization and avoid acute mountain sickness (AMS) following the first night of sleep at high altitude. Using multiple logistic regression and a comprehensive database, we developed a quantitative prediction model using ascent profile as the independent ... Read more >>

Physiol Rep (Physiological reports)
[2019, 7(20):e14263]

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