<h4>Objective</h4>to evaluate the role of Contrast-Enhanced Ultrasound (CEUS) of the Simple Rules (SR) from the International Ovarian Tumor Analysis group for the differential diagnosis of benign and malignant adnexal tumors.<h4>Methods</h4>A total of 180 patients with suspected malignant adnexal masses admitted to Lanzhou University Second Hospital were included, all of whom received conventional ultrasound (US) and CEUS examination before surgery. All masses were assessed using SR in US and SR in CEUS respectively. To compare the diagnostic performance , the sensitivity, specificity, negative and positive predictive values , Youden index and area under the curves values of SR in US and SR in CEUS were obtained.<h4>Results</h4>SR in CEUS was better than SR in US with its sensitivity, negative predictive values , Youden index and area under the curves . The specificity and negative predictive value of SR in CEUS were lower than that of SR in US. Compared with SR in US, SR in CEUS significantly reduced the number of uncertain masses(21, 36.7% vs 66, 11.7%).<h4>Conclusion</h4>We concluded that SR in CEUS performed well in the diagnosis of malignant adnexal masses. SR in CEUS is a supplement to SR in US.
Int J Gynaecol Obstet (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics)
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