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Paraneoplastic Limbic Encephalitis Secondary to SCLC on 18F-FDG PET/CT.

PMID: 33939650 (view PubMed database entry)
DOI: 10.1097/rlu.0000000000003628 (read at publisher's website )

Alinne Fernanda Amaral Verçosa, Isabella Araújo Mota, Maria Eduarda Duarte de Mello Flamini, Rodrigo de Carvalho Flamini,

<h4>Abstract</h4>A 67-year-old man with rapidly neurologic deterioration and 15 kg weight loss in 2 months was extensively evaluated by several medical specialties and conventional image examinations, with no diagnostic definition. 18F-FDG PET/CT was performed, showing glycolytic hypermetabolism in the hippocampus, cerebral hypometabolism with posterior temporoparietal pattern, multiple cervical and supraclavicular lymph nodes, and mediastinal hypermetabolic and enlarged lymph nodes, suggesting paraneoplastic limbic encephalitis, Alzheimer dementia, and lymphoma. Lymph node biopsy resulted in small cell lung carcinoma. The patient presented rapid clinical deterioration and died.

Clin Nucl Med (Clinical nuclear medicine)
[2021, 46(6):494-496]

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