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Persistence of Hepatitis B Immune Memory Until 6 Years of Age Following Hexavalent DTaP-IPV-HB-PRP~T Vaccination in a 3-, 5- and 11- to 12-month Schedule and Response to a Subsequent Hepatitis B Challenge Vaccination.

PMID: 33284254 (view PubMed database entry)
DOI: 10.1097/inf.0000000000002954 (read at publisher's website )

Miia Virta, Anu Soininen, Dhaval M Patel, Céline Petit, Cynthia Tabar, Olga Lyabis,

Anti-hepatitis B (HBs) antibody persistence and hepatitis B challenge were evaluated at 6 years of age following vaccination of fully liquid DTaP-IPV-HB-PRP~T or reconstituted DTaP-IPV-HB//PRP~T at 3, 5, 11-12 months of age. At 6 years, 53.8% and 73.5% had seroprotective anti-HBs antibodies (≥10 mIU/mL), increasing to 96.7% and 95.9% postchallenge, confirming a strong anamnestic response in primed vaccinees.

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(1):e28-e30]

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