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Characteristics and Mortality Determinants of COVID-19 Patients Undergoing Haemodialysis.

PMID: 32950045 (view PubMed database entry)
DOI: 10.3906/sag-2006-54 (read at publisher's website )

SavaŞ Sİpahİ, Hamad Dheİr, Aysel ToÇoĞlu, Melİke BektaŞ, Seyyİd Bİlal AÇikgÖz, Ahmed Cİhad GenÇ, Fuldem Mutlu, Mehmet KÖroĞlu, Alİ Fuat Erdem, OĞuz Karabay,

BACKGROUND/AIM:COVID-19 infection which started in Wuhan City, China in December 2019 turned into a pandemic in a very short time, affecting mainly the elderly and those with serious chronic illnesses. COVID-19 infection has been observed with a high mortality rate especially in patients undergoing maintenance haemodialysis. MATERIALS AND METHODS:Forty-two patients over 18 years of age, who underwent a maintenance haemodialysis program at our unit, and being tested positive for COVID-19 by PCR from nasopharyngeal swabs and/or were observed to have disease-related signs in their CTs were included in the study. RESULTS:In this study, 23 of 42 patients receiving haemodialysis support in our clinic were included. The median age was 67 years (min 35; max 91 years) and all of them had primary hypertension and other comorbidities. Their clinical evaluation showed that dry cough (47.8%) and shortness of breath (47.8%) were the most common symptoms. Fever was less pronounced (30.4%). The median time from the onset of symptoms to hospitalization was 1 day (min 0; max ) and time from hospitalization to death was 18 days (min:1; max 22). Transfer from the inpatient ward to ICU took a median of 7 days (min 1; max 13). Among the 23 patients, three died during the follow-up and 20 were discharged with full recovery. Baseline ferritin, procalcitonin levels and CRP/albumin rates higher and neutrophil/lymphocyte levels lower in patient who died. In these patients, despite being non-significant, there were more diabetic patients and D-dimer levels were higher than 1000 ugFEU/L. CONCLUSION:COVID-19 infection is associated with increased mortalit in chronic kidney diseases patients. Despite being non-significant, there was a trend towards increased mortality in patient with diabetes, D-dimer levels >1000 ugFEU/L and higher ferritin, prokalsitonin levels, increased CRP/albumin raio and lower neutrophil/lymphocyte ratio.

Turk J Med Sci (Turkish journal of medical sciences)
[2020, :]

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